Complex 1 protein (LYR family)/Complex1 LYR-like, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Complex 1 protein (LYR family), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJR9_LEIDO

TriTrypDb:

LdBPK_181210.1 , LdCL_180017300 , LDHU3_18.1530

Length:

270

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005739	mitochondrion	5	4
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043231	intracellular membrane-bounded organelle	4	4
GO:0110165	cellular anatomical entity	1	4

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Expansion

Sequence features

A0A3Q8IJR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJR9

Function

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Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	4
GO:0016043	cellular component organization	3	4
GO:0022607	cellular component assembly	4	4
GO:0033108	mitochondrial respiratory chain complex assembly	6	4
GO:0034552	respiratory chain complex II assembly	6	4
GO:0034553	mitochondrial respiratory chain complex II assembly	7	4
GO:0043933	protein-containing complex organization	4	4
GO:0065003	protein-containing complex assembly	5	4
GO:0071840	cellular component organization or biogenesis	2	4

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	158	160	PF00675	0.621
CLV_NRD_NRD_1	190	192	PF00675	0.580
CLV_NRD_NRD_1	218	220	PF00675	0.446
CLV_NRD_NRD_1	236	238	PF00675	0.334
CLV_NRD_NRD_1	251	253	PF00675	0.334
CLV_NRD_NRD_1	46	48	PF00675	0.672
CLV_NRD_NRD_1	56	58	PF00675	0.562
CLV_PCSK_FUR_1	12	16	PF00082	0.728
CLV_PCSK_FUR_1	54	58	PF00082	0.585
CLV_PCSK_KEX2_1	14	16	PF00082	0.612

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8U5	Leptomonas seymouri	49%	98%
A4H9N0	Leishmania braziliensis	67%	100%
A4HXZ4	Leishmania infantum	99%	100%
E9ARQ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4QDS2	Leishmania major	89%	100%

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