Apolipophorin

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Apolipophorin

Gene product:

Domain of unknown function (DUF4496), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJR1_LEIDO

TriTrypDb:

LdBPK_365340.1 , LdCL_360060600 , LDHU3_36.7120

Length:

264

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005929	cilium	4	1
GO:0005930	axoneme	2	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0120025	plasma membrane bounded cell projection	3	1

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Expansion

Sequence features

A0A3Q8IJR1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJR1

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	24	28	PF00656	0.373
CLV_C14_Caspase3-7	249	253	PF00656	0.573
CLV_NRD_NRD_1	260	262	PF00675	0.625
CLV_PCSK_KEX2_1	260	262	PF00082	0.680
CLV_PCSK_KEX2_1	61	63	PF00082	0.318
CLV_PCSK_PC1ET2_1	61	63	PF00082	0.308
CLV_PCSK_SKI1_1	107	111	PF00082	0.539
CLV_PCSK_SKI1_1	186	190	PF00082	0.288
CLV_PCSK_SKI1_1	78	82	PF00082	0.312
DEG_APCC_DBOX_1	185	193	PF00400	0.288

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P360	Leptomonas seymouri	77%	100%
A0A1X0NFH5	Trypanosomatidae	53%	100%
A0A422N6F8	Trypanosoma rangeli	55%	83%
A4HQ27	Leishmania braziliensis	86%	100%
A4IDT3	Leishmania infantum	100%	100%
D0A8U1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
E9ATU5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4Q0Q1	Leishmania major	95%	100%

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