Snf7_putative/Pfam:PF03357

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Snf7, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJN8_LEIDO

TriTrypDb:

LdBPK_364040.1 , LdCL_360047400 , LDHU3_36.5420

Length:

225

Annotations

Annotations by Jardim et al.

Vesicle mediated transport, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

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Cellular components
Term	Name	Level	Count
GO:0000815	ESCRT III complex	3	2
GO:0005768	endosome	7	2
GO:0005770	late endosome	8	2
GO:0005771	multivesicular body	9	2
GO:0009898	cytoplasmic side of plasma membrane	4	1
GO:0031410	cytoplasmic vesicle	6	2
GO:0031982	vesicle	4	2
GO:0032991	protein-containing complex	1	2
GO:0036452	ESCRT complex	2	2
GO:0043226	organelle	2	2

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Phosphorylation

Amastigote: 104

Expansion

Sequence features

A0A3Q8IJN8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJN8

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	14
GO:0006900	vesicle budding from membrane	5	2
GO:0006996	organelle organization	4	2
GO:0007034	vacuolar transport	4	14
GO:0009987	cellular process	1	14
GO:0016043	cellular component organization	3	2
GO:0016050	vesicle organization	5	2
GO:0016192	vesicle-mediated transport	4	2
GO:0016197	endosomal transport	4	2
GO:0032509	endosome transport via multivesicular body sorting pathway	5	2

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	30	34	PF00656	0.413
CLV_NRD_NRD_1	74	76	PF00675	0.359
CLV_PCSK_KEX2_1	121	123	PF00082	0.437
CLV_PCSK_KEX2_1	41	43	PF00082	0.337
CLV_PCSK_KEX2_1	48	50	PF00082	0.343
CLV_PCSK_KEX2_1	74	76	PF00082	0.359
CLV_PCSK_PC1ET2_1	121	123	PF00082	0.467
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.337
CLV_PCSK_PC1ET2_1	48	50	PF00082	0.336
CLV_PCSK_PC1ET2_1	74	76	PF00082	0.372

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5W8	Leptomonas seymouri	83%	100%
A0A0N1ILA5	Leptomonas seymouri	35%	100%
A0A0S4J9L8	Bodo saltans	28%	100%
A0A0S4JI05	Bodo saltans	55%	93%
A0A1X0NJR2	Trypanosomatidae	31%	100%
A0A1X0P4I7	Trypanosomatidae	61%	99%
A0A3R7NQB4	Trypanosoma rangeli	57%	99%
A0A3S7WU01	Leishmania donovani	34%	100%
A0A3S7X8S3	Leishmania donovani	28%	100%
A0A422NAN8	Trypanosoma rangeli	31%	100%

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