60S ribosomal protein L29

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L29, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJK1_LEIDO

TriTrypDb:

LdBPK_363550.1 , LdCL_360042500 , LdCL_360042600 , LDHU3_36.4830

Length:

Annotations

Annotations by Jardim et al.

Ribosomal Protein, ribosomal L29

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	9
GO:0032991	protein-containing complex	1	10
GO:0043226	organelle	2	9
GO:0043228	non-membrane-bounded organelle	3	9
GO:0043229	intracellular organelle	3	9
GO:0043232	intracellular non-membrane-bounded organelle	4	9
GO:0110165	cellular anatomical entity	1	9
GO:1990904	ribonucleoprotein complex	2	10
GO:0015934	large ribosomal subunit	4	1
GO:0022625	cytosolic large ribosomal subunit	5	1
GO:0044391	ribosomal subunit	3	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3Q8IJK1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJK1

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	10
GO:0006518	peptide metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009058	biosynthetic process	2	10
GO:0009059	macromolecule biosynthetic process	4	10
GO:0009987	cellular process	1	10
GO:0019538	protein metabolic process	3	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	10
GO:0043043	peptide biosynthetic process	5	10
GO:0043170	macromolecule metabolic process	3	10
GO:0043603	amide metabolic process	3	10
GO:0043604	amide biosynthetic process	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044249	cellular biosynthetic process	3	10
GO:0044260	obsolete cellular macromolecule metabolic process	3	10
GO:0044271	cellular nitrogen compound biosynthetic process	4	10
GO:0071704	organic substance metabolic process	2	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901566	organonitrogen compound biosynthetic process	4	10
GO:1901576	organic substance biosynthetic process	3	10
GO:0002181	cytoplasmic translation	5	1

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	10
GO:0005198	structural molecule activity	1	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	45	47	PF00675	0.441
CLV_NRD_NRD_1	59	61	PF00675	0.469
CLV_PCSK_KEX2_1	33	35	PF00082	0.474
CLV_PCSK_KEX2_1	45	47	PF00082	0.413
CLV_PCSK_KEX2_1	58	60	PF00082	0.475
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.489
CLV_PCSK_PC1ET2_1	58	60	PF00082	0.551
CLV_PCSK_SKI1_1	53	57	PF00082	0.497
DOC_MAPK_MEF2A_6	22	29	PF00069	0.282
DOC_USP7_UBL2_3	49	53	PF12436	0.471
LIG_BIR_II_1	1	5	PF00653	0.270
MOD_GSK3_1	1	8	PF00069	0.270
MOD_GSK3_1	29	36	PF00069	0.479
MOD_N-GLC_1	5	10	PF02516	0.270
MOD_NEK2_1	1	6	PF00069	0.270
MOD_NEK2_1	29	34	PF00069	0.502
MOD_PKA_1	33	39	PF00069	0.518
MOD_PKA_2	33	39	PF00069	0.459
MOD_Plk_4	33	39	PF00069	0.458
TRG_ER_diArg_1	45	48	PF00400	0.446

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5Z8	Leptomonas seymouri	96%	100%
A0A0S4JE25	Bodo saltans	78%	97%
A4HPK6	Leishmania braziliensis	94%	100%
A4ID57	Leishmania infantum	97%	100%
A4ID58	Leishmania infantum	100%	100%
D0A8K6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	99%
E9ATB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q24154	Drosophila melanogaster	49%	92%
Q4Q178	Leishmania major	99%	100%
Q84WM0	Arabidopsis thaliana	56%	100%
Q9M7X7	Arabidopsis thaliana	58%	100%