Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IJG2_LEIDO

TriTrypDb:

LdBPK_322660.1 , LdCL_320032400 , LDHU3_32.3330

Length:

920

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJG2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJG2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	265	269	PF00656	0.676
CLV_C14_Caspase3-7	639	643	PF00656	0.718
CLV_C14_Caspase3-7	708	712	PF00656	0.708
CLV_NRD_NRD_1	179	181	PF00675	0.688
CLV_NRD_NRD_1	211	213	PF00675	0.735
CLV_NRD_NRD_1	280	282	PF00675	0.739
CLV_NRD_NRD_1	290	292	PF00675	0.624
CLV_NRD_NRD_1	313	315	PF00675	0.711
CLV_NRD_NRD_1	455	457	PF00675	0.740
CLV_NRD_NRD_1	461	463	PF00675	0.700
CLV_NRD_NRD_1	513	515	PF00675	0.742
CLV_NRD_NRD_1	516	518	PF00675	0.728
CLV_NRD_NRD_1	519	521	PF00675	0.695
CLV_NRD_NRD_1	523	525	PF00675	0.635
CLV_NRD_NRD_1	574	576	PF00675	0.711
CLV_NRD_NRD_1	647	649	PF00675	0.675
CLV_NRD_NRD_1	704	706	PF00675	0.658
CLV_NRD_NRD_1	796	798	PF00675	0.628
CLV_NRD_NRD_1	841	843	PF00675	0.686
CLV_NRD_NRD_1	873	875	PF00675	0.692
CLV_PCSK_FUR_1	177	181	PF00082	0.693
CLV_PCSK_FUR_1	275	279	PF00082	0.751
CLV_PCSK_FUR_1	506	510	PF00082	0.724
CLV_PCSK_FUR_1	511	515	PF00082	0.706
CLV_PCSK_FUR_1	517	521	PF00082	0.657
CLV_PCSK_FUR_1	838	842	PF00082	0.637
CLV_PCSK_FUR_1	870	874	PF00082	0.724
CLV_PCSK_KEX2_1	179	181	PF00082	0.688
CLV_PCSK_KEX2_1	210	212	PF00082	0.735
CLV_PCSK_KEX2_1	275	277	PF00082	0.777
CLV_PCSK_KEX2_1	278	280	PF00082	0.759
CLV_PCSK_KEX2_1	289	291	PF00082	0.697
CLV_PCSK_KEX2_1	312	314	PF00082	0.716
CLV_PCSK_KEX2_1	455	457	PF00082	0.737
CLV_PCSK_KEX2_1	461	463	PF00082	0.697
CLV_PCSK_KEX2_1	508	510	PF00082	0.729
CLV_PCSK_KEX2_1	511	513	PF00082	0.723
CLV_PCSK_KEX2_1	516	518	PF00082	0.689
CLV_PCSK_KEX2_1	519	521	PF00082	0.655
CLV_PCSK_KEX2_1	522	524	PF00082	0.608
CLV_PCSK_KEX2_1	574	576	PF00082	0.687
CLV_PCSK_KEX2_1	647	649	PF00082	0.676
CLV_PCSK_KEX2_1	704	706	PF00082	0.658
CLV_PCSK_KEX2_1	796	798	PF00082	0.712
CLV_PCSK_KEX2_1	840	842	PF00082	0.688
CLV_PCSK_KEX2_1	872	874	PF00082	0.704
CLV_PCSK_KEX2_1	899	901	PF00082	0.684
CLV_PCSK_PC1ET2_1	899	901	PF00082	0.696
CLV_PCSK_PC7_1	275	281	PF00082	0.744
CLV_PCSK_PC7_1	506	512	PF00082	0.696
CLV_PCSK_PC7_1	519	525	PF00082	0.605
CLV_PCSK_PC7_1	868	874	PF00082	0.633
CLV_PCSK_SKI1_1	45	49	PF00082	0.616
CLV_PCSK_SKI1_1	696	700	PF00082	0.698
CLV_PCSK_SKI1_1	750	754	PF00082	0.680
DEG_Nend_Nbox_1	1	3	PF02207	0.655
DEG_SPOP_SBC_1	132	136	PF00917	0.583
DEG_SPOP_SBC_1	241	245	PF00917	0.586
DEG_SPOP_SBC_1	374	378	PF00917	0.669
DEG_SPOP_SBC_1	446	450	PF00917	0.688
DEG_SPOP_SBC_1	887	891	PF00917	0.688
DOC_ANK_TNKS_1	279	286	PF00023	0.677
DOC_CKS1_1	393	398	PF01111	0.629
DOC_PP2B_LxvP_1	604	607	PF13499	0.675
DOC_PP4_FxxP_1	108	111	PF00568	0.636
DOC_USP7_MATH_1	11	15	PF00917	0.686
DOC_USP7_MATH_1	130	134	PF00917	0.699
DOC_USP7_MATH_1	147	151	PF00917	0.741
DOC_USP7_MATH_1	159	163	PF00917	0.700
DOC_USP7_MATH_1	193	197	PF00917	0.785
DOC_USP7_MATH_1	242	246	PF00917	0.718
DOC_USP7_MATH_1	29	33	PF00917	0.612
DOC_USP7_MATH_1	293	297	PF00917	0.674
DOC_USP7_MATH_1	347	351	PF00917	0.759
DOC_USP7_MATH_1	372	376	PF00917	0.721
DOC_USP7_MATH_1	381	385	PF00917	0.682
DOC_USP7_MATH_1	464	468	PF00917	0.694
DOC_USP7_MATH_1	501	505	PF00917	0.755
DOC_USP7_MATH_1	529	533	PF00917	0.800
DOC_USP7_MATH_1	542	546	PF00917	0.640
DOC_USP7_MATH_1	63	67	PF00917	0.701
DOC_USP7_MATH_1	653	657	PF00917	0.747
DOC_USP7_MATH_1	659	663	PF00917	0.737
DOC_USP7_MATH_1	718	722	PF00917	0.673
DOC_USP7_MATH_1	738	742	PF00917	0.539
DOC_USP7_MATH_1	787	791	PF00917	0.724
DOC_USP7_MATH_2	816	822	PF00917	0.578
DOC_USP7_UBL2_3	895	899	PF12436	0.670
DOC_WW_Pin1_4	148	153	PF00397	0.651
DOC_WW_Pin1_4	169	174	PF00397	0.607
DOC_WW_Pin1_4	185	190	PF00397	0.742
DOC_WW_Pin1_4	194	199	PF00397	0.647
DOC_WW_Pin1_4	291	296	PF00397	0.746
DOC_WW_Pin1_4	362	367	PF00397	0.778
DOC_WW_Pin1_4	392	397	PF00397	0.710
DOC_WW_Pin1_4	411	416	PF00397	0.611
DOC_WW_Pin1_4	427	432	PF00397	0.671
DOC_WW_Pin1_4	437	442	PF00397	0.696
DOC_WW_Pin1_4	460	465	PF00397	0.699
DOC_WW_Pin1_4	481	486	PF00397	0.543
DOC_WW_Pin1_4	522	527	PF00397	0.682
DOC_WW_Pin1_4	545	550	PF00397	0.681
DOC_WW_Pin1_4	58	63	PF00397	0.688
DOC_WW_Pin1_4	649	654	PF00397	0.696
DOC_WW_Pin1_4	66	71	PF00397	0.653
DOC_WW_Pin1_4	730	735	PF00397	0.661
DOC_WW_Pin1_4	759	764	PF00397	0.718
DOC_WW_Pin1_4	847	852	PF00397	0.748
DOC_WW_Pin1_4	872	877	PF00397	0.714
LIG_14-3-3_CanoR_1	289	298	PF00244	0.694
LIG_14-3-3_CanoR_1	455	464	PF00244	0.699
LIG_14-3-3_CanoR_1	756	764	PF00244	0.616
LIG_BIR_III_4	642	646	PF00653	0.666
LIG_CtBP_PxDLS_1	777	781	PF00389	0.680
LIG_EVH1_1	731	735	PF00568	0.587
LIG_FHA_1	133	139	PF00498	0.660
LIG_FHA_1	389	395	PF00498	0.695
LIG_FHA_1	752	758	PF00498	0.658
LIG_FHA_2	233	239	PF00498	0.698
LIG_GSK3_LRP6_1	411	416	PF00069	0.573
LIG_Integrin_RGD_1	180	182	PF01839	0.742
LIG_LIR_Apic_2	85	89	PF02991	0.639
LIG_LIR_Nem_3	233	239	PF02991	0.818
LIG_MYND_1	396	400	PF01753	0.607
LIG_Pex14_2	236	240	PF04695	0.728
LIG_Pex14_2	699	703	PF04695	0.699
LIG_REV1ctd_RIR_1	570	579	PF16727	0.709
LIG_SH2_CRK	100	104	PF00017	0.560
LIG_SH2_CRK	86	90	PF00017	0.628
LIG_SH2_NCK_1	224	228	PF00017	0.693
LIG_SH2_STAP1	612	616	PF00017	0.665
LIG_SH2_STAT5	224	227	PF00017	0.674
LIG_SH3_1	810	816	PF00018	0.643
LIG_SH3_2	195	200	PF14604	0.665
LIG_SH3_3	118	124	PF00018	0.664
LIG_SH3_3	192	198	PF00018	0.672
LIG_SH3_3	236	242	PF00018	0.586
LIG_SH3_3	250	256	PF00018	0.839
LIG_SH3_3	292	298	PF00018	0.853
LIG_SH3_3	394	400	PF00018	0.745
LIG_SH3_3	406	412	PF00018	0.633
LIG_SH3_3	416	422	PF00018	0.702
LIG_SH3_3	425	431	PF00018	0.695
LIG_SH3_3	436	442	PF00018	0.745
LIG_SH3_3	53	59	PF00018	0.630
LIG_SH3_3	544	550	PF00018	0.685
LIG_SH3_3	597	603	PF00018	0.614
LIG_SH3_3	729	735	PF00018	0.590
LIG_SH3_3	77	83	PF00018	0.596
LIG_SH3_3	810	816	PF00018	0.643
LIG_SUMO_SIM_par_1	399	405	PF11976	0.761
LIG_TRAF2_1	594	597	PF00917	0.657
LIG_UBA3_1	601	609	PF00899	0.574
LIG_UBA3_1	698	707	PF00899	0.653
LIG_WRC_WIRS_1	569	574	PF05994	0.635
LIG_WW_3	767	771	PF00397	0.661
MOD_CDC14_SPxK_1	197	200	PF00782	0.666
MOD_CDC14_SPxK_1	365	368	PF00782	0.727
MOD_CDK_SPK_2	169	174	PF00069	0.688
MOD_CDK_SPK_2	522	527	PF00069	0.670
MOD_CDK_SPxK_1	194	200	PF00069	0.668
MOD_CDK_SPxK_1	362	368	PF00069	0.731
MOD_CDK_SPxK_1	649	655	PF00069	0.699
MOD_CDK_SPxK_1	759	765	PF00069	0.650
MOD_CDK_SPxxK_3	527	534	PF00069	0.621
MOD_CK1_1	133	139	PF00069	0.594
MOD_CK1_1	150	156	PF00069	0.672
MOD_CK1_1	158	164	PF00069	0.640
MOD_CK1_1	172	178	PF00069	0.634
MOD_CK1_1	220	226	PF00069	0.695
MOD_CK1_1	294	300	PF00069	0.702
MOD_CK1_1	375	381	PF00069	0.672
MOD_CK1_1	467	473	PF00069	0.723
MOD_CK1_1	489	495	PF00069	0.730
MOD_CK1_1	502	508	PF00069	0.650
MOD_CK1_1	530	536	PF00069	0.732
MOD_CK1_1	545	551	PF00069	0.564
MOD_CK1_1	638	644	PF00069	0.779
MOD_CK1_1	66	72	PF00069	0.655
MOD_CK1_1	662	668	PF00069	0.726
MOD_CK1_1	692	698	PF00069	0.733
MOD_CK1_1	733	739	PF00069	0.668
MOD_CK1_1	741	747	PF00069	0.599
MOD_CK1_1	779	785	PF00069	0.616
MOD_CK1_1	882	888	PF00069	0.718
MOD_CK1_1	889	895	PF00069	0.686
MOD_CK2_1	232	238	PF00069	0.715
MOD_CK2_1	294	300	PF00069	0.694
MOD_CK2_1	489	495	PF00069	0.680
MOD_CK2_1	522	528	PF00069	0.670
MOD_CK2_1	553	559	PF00069	0.702
MOD_Cter_Amidation	273	276	PF01082	0.750
MOD_Cter_Amidation	517	520	PF01082	0.746
MOD_Cter_Amidation	838	841	PF01082	0.588
MOD_Cter_Amidation	870	873	PF01082	0.679
MOD_DYRK1A_RPxSP_1	58	62	PF00069	0.589
MOD_GlcNHglycan	13	16	PF01048	0.630
MOD_GlcNHglycan	157	160	PF01048	0.685
MOD_GlcNHglycan	161	164	PF01048	0.685
MOD_GlcNHglycan	174	177	PF01048	0.733
MOD_GlcNHglycan	219	222	PF01048	0.644
MOD_GlcNHglycan	244	247	PF01048	0.645
MOD_GlcNHglycan	31	34	PF01048	0.706
MOD_GlcNHglycan	336	339	PF01048	0.772
MOD_GlcNHglycan	358	361	PF01048	0.689
MOD_GlcNHglycan	404	407	PF01048	0.636
MOD_GlcNHglycan	434	437	PF01048	0.687
MOD_GlcNHglycan	464	467	PF01048	0.800
MOD_GlcNHglycan	470	473	PF01048	0.703
MOD_GlcNHglycan	495	498	PF01048	0.765
MOD_GlcNHglycan	501	504	PF01048	0.677
MOD_GlcNHglycan	544	547	PF01048	0.637
MOD_GlcNHglycan	577	580	PF01048	0.767
MOD_GlcNHglycan	584	587	PF01048	0.787
MOD_GlcNHglycan	65	68	PF01048	0.655
MOD_GlcNHglycan	662	665	PF01048	0.857
MOD_GlcNHglycan	686	689	PF01048	0.727
MOD_GlcNHglycan	691	694	PF01048	0.717
MOD_GlcNHglycan	719	723	PF01048	0.697
MOD_GlcNHglycan	740	743	PF01048	0.645
MOD_GlcNHglycan	765	768	PF01048	0.677
MOD_GlcNHglycan	833	836	PF01048	0.698
MOD_GlcNHglycan	859	862	PF01048	0.747
MOD_GlcNHglycan	901	904	PF01048	0.720
MOD_GlcNHglycan	906	909	PF01048	0.665
MOD_GSK3_1	128	135	PF00069	0.685
MOD_GSK3_1	155	162	PF00069	0.699
MOD_GSK3_1	185	192	PF00069	0.659
MOD_GSK3_1	222	229	PF00069	0.716
MOD_GSK3_1	242	249	PF00069	0.649
MOD_GSK3_1	289	296	PF00069	0.670
MOD_GSK3_1	352	359	PF00069	0.790
MOD_GSK3_1	362	369	PF00069	0.672
MOD_GSK3_1	388	395	PF00069	0.753
MOD_GSK3_1	456	463	PF00069	0.759
MOD_GSK3_1	464	471	PF00069	0.678
MOD_GSK3_1	472	479	PF00069	0.558
MOD_GSK3_1	489	496	PF00069	0.808
MOD_GSK3_1	649	656	PF00069	0.760
MOD_GSK3_1	65	72	PF00069	0.706
MOD_GSK3_1	675	682	PF00069	0.734
MOD_GSK3_1	733	740	PF00069	0.674
MOD_GSK3_1	741	748	PF00069	0.635
MOD_GSK3_1	759	766	PF00069	0.564
MOD_GSK3_1	795	802	PF00069	0.686
MOD_GSK3_1	877	884	PF00069	0.731
MOD_GSK3_1	885	892	PF00069	0.647
MOD_LATS_1	454	460	PF00433	0.716
MOD_N-GLC_1	372	377	PF02516	0.700
MOD_N-GLC_1	553	558	PF02516	0.761
MOD_N-GLC_1	575	580	PF02516	0.658
MOD_N-GLC_1	675	680	PF02516	0.675
MOD_N-GLC_1	723	728	PF02516	0.666
MOD_N-GLC_1	745	750	PF02516	0.681
MOD_N-GLC_1	842	847	PF02516	0.694
MOD_N-GLC_2	44	46	PF02516	0.607
MOD_N-GLC_2	881	883	PF02516	0.691
MOD_NEK2_1	346	351	PF00069	0.750
MOD_NEK2_1	468	473	PF00069	0.678
MOD_NEK2_1	488	493	PF00069	0.593
MOD_NEK2_1	611	616	PF00069	0.706
MOD_NEK2_1	757	762	PF00069	0.604
MOD_NEK2_1	778	783	PF00069	0.670
MOD_NEK2_1	795	800	PF00069	0.550
MOD_NEK2_1	877	882	PF00069	0.688
MOD_NEK2_2	568	573	PF00069	0.635
MOD_NEK2_2	612	617	PF00069	0.607
MOD_NEK2_2	751	756	PF00069	0.645
MOD_PIKK_1	139	145	PF00454	0.700
MOD_PIKK_1	226	232	PF00454	0.742
MOD_PIKK_1	653	659	PF00454	0.715
MOD_PIKK_1	818	824	PF00454	0.646
MOD_PIKK_1	826	832	PF00454	0.638
MOD_PKA_1	289	295	PF00069	0.693
MOD_PKA_1	796	802	PF00069	0.604
MOD_PKA_1	899	905	PF00069	0.691
MOD_PKA_2	289	295	PF00069	0.738
MOD_PKA_2	795	801	PF00069	0.682
MOD_PKA_2	857	863	PF00069	0.701
MOD_PKA_2	899	905	PF00069	0.691
MOD_PKB_1	840	848	PF00069	0.649
MOD_Plk_1	553	559	PF00069	0.741
MOD_Plk_1	596	602	PF00069	0.601
MOD_Plk_1	612	618	PF00069	0.755
MOD_Plk_1	723	729	PF00069	0.667
MOD_Plk_4	389	395	PF00069	0.675
MOD_Plk_4	568	574	PF00069	0.637
MOD_Plk_4	596	602	PF00069	0.601
MOD_ProDKin_1	148	154	PF00069	0.653
MOD_ProDKin_1	169	175	PF00069	0.610
MOD_ProDKin_1	185	191	PF00069	0.743
MOD_ProDKin_1	194	200	PF00069	0.648
MOD_ProDKin_1	291	297	PF00069	0.747
MOD_ProDKin_1	362	368	PF00069	0.779
MOD_ProDKin_1	392	398	PF00069	0.710
MOD_ProDKin_1	411	417	PF00069	0.617
MOD_ProDKin_1	427	433	PF00069	0.670
MOD_ProDKin_1	437	443	PF00069	0.697
MOD_ProDKin_1	460	466	PF00069	0.697
MOD_ProDKin_1	481	487	PF00069	0.540
MOD_ProDKin_1	522	528	PF00069	0.682
MOD_ProDKin_1	545	551	PF00069	0.682
MOD_ProDKin_1	58	64	PF00069	0.691
MOD_ProDKin_1	649	655	PF00069	0.699
MOD_ProDKin_1	66	72	PF00069	0.651
MOD_ProDKin_1	730	736	PF00069	0.661
MOD_ProDKin_1	759	765	PF00069	0.722
MOD_ProDKin_1	847	853	PF00069	0.746
MOD_ProDKin_1	872	878	PF00069	0.713
MOD_SUMO_rev_2	14	20	PF00179	0.550
MOD_SUMO_rev_2	300	310	PF00179	0.695
TRG_ENDOCYTIC_2	100	103	PF00928	0.670
TRG_ER_diArg_1	177	180	PF00400	0.695
TRG_ER_diArg_1	210	212	PF00400	0.674
TRG_ER_diArg_1	275	278	PF00400	0.750
TRG_ER_diArg_1	279	281	PF00400	0.706
TRG_ER_diArg_1	289	291	PF00400	0.582
TRG_ER_diArg_1	312	314	PF00400	0.709
TRG_ER_diArg_1	455	458	PF00400	0.739
TRG_ER_diArg_1	508	511	PF00400	0.736
TRG_ER_diArg_1	512	514	PF00400	0.721
TRG_ER_diArg_1	516	519	PF00400	0.683
TRG_ER_diArg_1	522	524	PF00400	0.601
TRG_ER_diArg_1	534	537	PF00400	0.574
TRG_ER_diArg_1	573	575	PF00400	0.713
TRG_ER_diArg_1	703	705	PF00400	0.655
TRG_ER_diArg_1	795	797	PF00400	0.624
TRG_ER_diArg_1	838	841	PF00400	0.632
TRG_ER_diArg_1	867	870	PF00400	0.715
TRG_ER_diArg_1	872	874	PF00400	0.688
TRG_NLS_MonoExtN_4	797	804	PF00514	0.688

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HKP2	Leishmania braziliensis	52%	100%
A4I873	Leishmania infantum	99%	100%
E9B331	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4Q523	Leishmania major	85%	100%