Kinesin motor domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IJF9_LEIDO

TriTrypDb:

LdBPK_354290.1 , LdCL_350048000 , LDHU3_35.5680

Length:

599

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJF9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	229	233	PF00656	0.717
CLV_NRD_NRD_1	273	275	PF00675	0.762
CLV_NRD_NRD_1	36	38	PF00675	0.828
CLV_NRD_NRD_1	578	580	PF00675	0.670
CLV_NRD_NRD_1	591	593	PF00675	0.657
CLV_PCSK_KEX2_1	216	218	PF00082	0.840
CLV_PCSK_KEX2_1	36	38	PF00082	0.828
CLV_PCSK_KEX2_1	586	588	PF00082	0.709
CLV_PCSK_KEX2_1	590	592	PF00082	0.733
CLV_PCSK_PC1ET2_1	216	218	PF00082	0.840
CLV_PCSK_PC1ET2_1	586	588	PF00082	0.716
CLV_PCSK_PC7_1	587	593	PF00082	0.787
CLV_PCSK_SKI1_1	216	220	PF00082	0.841
CLV_PCSK_SKI1_1	24	28	PF00082	0.762
CLV_PCSK_SKI1_1	387	391	PF00082	0.759
CLV_PCSK_SKI1_1	497	501	PF00082	0.630
DEG_SPOP_SBC_1	160	164	PF00917	0.640
DEG_SPOP_SBC_1	435	439	PF00917	0.776
DOC_CKS1_1	125	130	PF01111	0.684
DOC_CYCLIN_yCln2_LP_2	250	256	PF00134	0.834
DOC_CYCLIN_yCln2_LP_2	273	279	PF00134	0.735
DOC_MAPK_HePTP_8	72	84	PF00069	0.588
DOC_MAPK_MEF2A_6	325	333	PF00069	0.610
DOC_MAPK_MEF2A_6	75	84	PF00069	0.726
DOC_PP2B_LxvP_1	250	253	PF13499	0.829
DOC_USP7_MATH_1	111	115	PF00917	0.857
DOC_USP7_MATH_1	118	122	PF00917	0.739
DOC_USP7_MATH_1	138	142	PF00917	0.526
DOC_USP7_MATH_1	206	210	PF00917	0.749
DOC_USP7_MATH_1	226	230	PF00917	0.788
DOC_USP7_MATH_1	231	235	PF00917	0.714
DOC_USP7_MATH_1	254	258	PF00917	0.838
DOC_USP7_MATH_1	321	325	PF00917	0.790
DOC_USP7_MATH_1	337	341	PF00917	0.544
DOC_USP7_MATH_1	348	352	PF00917	0.554
DOC_USP7_MATH_1	360	364	PF00917	0.617
DOC_USP7_MATH_1	373	377	PF00917	0.630
DOC_USP7_MATH_1	396	400	PF00917	0.738
DOC_USP7_MATH_1	435	439	PF00917	0.631
DOC_USP7_MATH_1	470	474	PF00917	0.637
DOC_USP7_MATH_1	510	514	PF00917	0.660
DOC_USP7_MATH_1	550	554	PF00917	0.770
DOC_USP7_UBL2_3	30	34	PF12436	0.725
DOC_WW_Pin1_4	120	125	PF00397	0.805
DOC_WW_Pin1_4	278	283	PF00397	0.778
DOC_WW_Pin1_4	49	54	PF00397	0.794
DOC_WW_Pin1_4	92	97	PF00397	0.773
LIG_14-3-3_CanoR_1	161	169	PF00244	0.748
LIG_14-3-3_CanoR_1	220	228	PF00244	0.772
LIG_14-3-3_CanoR_1	267	276	PF00244	0.761
LIG_14-3-3_CanoR_1	362	369	PF00244	0.762
LIG_14-3-3_CanoR_1	381	386	PF00244	0.525
LIG_14-3-3_CanoR_1	511	521	PF00244	0.793
LIG_14-3-3_CanoR_1	522	527	PF00244	0.703
LIG_Actin_WH2_2	464	481	PF00022	0.638
LIG_BIR_II_1	1	5	PF00653	0.713
LIG_BRCT_BRCA1_1	568	572	PF00533	0.653
LIG_FHA_1	125	131	PF00498	0.701
LIG_FHA_1	135	141	PF00498	0.628
LIG_FHA_1	268	274	PF00498	0.622
LIG_FHA_1	424	430	PF00498	0.696
LIG_FHA_1	456	462	PF00498	0.605
LIG_FHA_1	480	486	PF00498	0.808
LIG_FHA_2	233	239	PF00498	0.835
LIG_FHA_2	592	598	PF00498	0.815
LIG_LIR_Apic_2	19	23	PF02991	0.698
LIG_LIR_Gen_1	438	448	PF02991	0.813
LIG_LIR_Gen_1	594	599	PF02991	0.820
LIG_LIR_Nem_3	402	408	PF02991	0.795
LIG_LIR_Nem_3	438	444	PF02991	0.812
LIG_LIR_Nem_3	447	451	PF02991	0.664
LIG_LIR_Nem_3	594	599	PF02991	0.820
LIG_MYND_1	124	128	PF01753	0.620
LIG_PDZ_Class_3	594	599	PF00595	0.820
LIG_SH2_CRK	441	445	PF00017	0.815
LIG_SH2_SRC	20	23	PF00017	0.772
LIG_SH2_SRC	403	406	PF00017	0.727
LIG_SH2_SRC	451	454	PF00017	0.704
LIG_SH2_STAP1	448	452	PF00017	0.717
LIG_SH2_STAT5	20	23	PF00017	0.772
LIG_SH3_2	211	216	PF14604	0.792
LIG_SH3_3	122	128	PF00018	0.624
LIG_SH3_3	208	214	PF00018	0.796
LIG_SH3_3	299	305	PF00018	0.759
LIG_SH3_3	315	321	PF00018	0.540
LIG_SH3_3	323	329	PF00018	0.641
LIG_SH3_3	349	355	PF00018	0.789
LIG_SH3_3	483	489	PF00018	0.789
LIG_SH3_3	501	507	PF00018	0.583
LIG_SH3_3	98	104	PF00018	0.790
LIG_WW_3	152	156	PF00397	0.620
LIG_WW_3	508	512	PF00397	0.726
MOD_CDK_SPK_2	49	54	PF00069	0.802
MOD_CK1_1	129	135	PF00069	0.669
MOD_CK1_1	163	169	PF00069	0.793
MOD_CK1_1	194	200	PF00069	0.790
MOD_CK1_1	209	215	PF00069	0.572
MOD_CK1_1	224	230	PF00069	0.634
MOD_CK1_1	234	240	PF00069	0.682
MOD_CK1_1	257	263	PF00069	0.620
MOD_CK1_1	278	284	PF00069	0.791
MOD_CK1_1	291	297	PF00069	0.643
MOD_CK1_1	377	383	PF00069	0.649
MOD_CK1_1	434	440	PF00069	0.685
MOD_CK1_1	473	479	PF00069	0.698
MOD_CK1_1	515	521	PF00069	0.822
MOD_CK1_1	544	550	PF00069	0.660
MOD_CK1_1	92	98	PF00069	0.752
MOD_CK2_1	232	238	PF00069	0.836
MOD_CK2_1	239	245	PF00069	0.725
MOD_CK2_1	391	397	PF00069	0.723
MOD_CK2_1	550	556	PF00069	0.732
MOD_GlcNHglycan	109	112	PF01048	0.770
MOD_GlcNHglycan	120	123	PF01048	0.642
MOD_GlcNHglycan	140	143	PF01048	0.657
MOD_GlcNHglycan	157	160	PF01048	0.570
MOD_GlcNHglycan	163	166	PF01048	0.700
MOD_GlcNHglycan	189	192	PF01048	0.756
MOD_GlcNHglycan	229	232	PF01048	0.723
MOD_GlcNHglycan	24	27	PF01048	0.499
MOD_GlcNHglycan	250	253	PF01048	0.767
MOD_GlcNHglycan	277	280	PF01048	0.831
MOD_GlcNHglycan	299	302	PF01048	0.842
MOD_GlcNHglycan	399	402	PF01048	0.796
MOD_GlcNHglycan	433	436	PF01048	0.667
MOD_GlcNHglycan	468	471	PF01048	0.760
MOD_GlcNHglycan	472	475	PF01048	0.733
MOD_GlcNHglycan	49	52	PF01048	0.688
MOD_GlcNHglycan	491	494	PF01048	0.613
MOD_GlcNHglycan	500	503	PF01048	0.695
MOD_GlcNHglycan	514	517	PF01048	0.588
MOD_GlcNHglycan	546	549	PF01048	0.661
MOD_GlcNHglycan	8	11	PF01048	0.786
MOD_GSK3_1	107	114	PF00069	0.768
MOD_GSK3_1	116	123	PF00069	0.671
MOD_GSK3_1	129	136	PF00069	0.664
MOD_GSK3_1	155	162	PF00069	0.702
MOD_GSK3_1	181	188	PF00069	0.796
MOD_GSK3_1	220	227	PF00069	0.810
MOD_GSK3_1	234	241	PF00069	0.604
MOD_GSK3_1	293	300	PF00069	0.816
MOD_GSK3_1	354	361	PF00069	0.728
MOD_GSK3_1	371	378	PF00069	0.656
MOD_GSK3_1	381	388	PF00069	0.616
MOD_GSK3_1	419	426	PF00069	0.831
MOD_GSK3_1	427	434	PF00069	0.695
MOD_GSK3_1	435	442	PF00069	0.549
MOD_GSK3_1	45	52	PF00069	0.733
MOD_GSK3_1	466	473	PF00069	0.712
MOD_GSK3_1	520	527	PF00069	0.654
MOD_GSK3_1	537	544	PF00069	0.589
MOD_GSK3_1	85	92	PF00069	0.734
MOD_N-GLC_1	111	116	PF02516	0.741
MOD_N-GLC_1	337	342	PF02516	0.609
MOD_N-GLC_1	566	571	PF02516	0.620
MOD_NEK2_1	219	224	PF00069	0.837
MOD_NEK2_1	385	390	PF00069	0.627
MOD_NEK2_1	423	428	PF00069	0.834
MOD_NEK2_1	478	483	PF00069	0.641
MOD_NEK2_1	535	540	PF00069	0.735
MOD_NEK2_2	239	244	PF00069	0.763
MOD_NEK2_2	329	334	PF00069	0.742
MOD_PIKK_1	116	122	PF00454	0.640
MOD_PIKK_1	423	429	PF00454	0.833
MOD_PIKK_1	99	105	PF00454	0.651
MOD_PK_1	375	381	PF00069	0.747
MOD_PK_1	541	547	PF00069	0.610
MOD_PKA_1	44	50	PF00069	0.700
MOD_PKA_1	591	597	PF00069	0.816
MOD_PKA_2	144	150	PF00069	0.807
MOD_PKA_2	154	160	PF00069	0.664
MOD_PKA_2	219	225	PF00069	0.837
MOD_PKA_2	297	303	PF00069	0.826
MOD_PKA_2	343	349	PF00069	0.826
MOD_PKA_2	361	367	PF00069	0.581
MOD_PKA_2	371	377	PF00069	0.629
MOD_PKA_2	380	386	PF00069	0.525
MOD_PKA_2	444	450	PF00069	0.696
MOD_PKA_2	478	484	PF00069	0.788
MOD_PKA_2	510	516	PF00069	0.742
MOD_PKA_2	591	597	PF00069	0.740
MOD_Plk_1	239	245	PF00069	0.782
MOD_Plk_1	329	335	PF00069	0.605
MOD_Plk_1	439	445	PF00069	0.814
MOD_Plk_1	45	51	PF00069	0.734
MOD_Plk_4	439	445	PF00069	0.728
MOD_ProDKin_1	120	126	PF00069	0.807
MOD_ProDKin_1	278	284	PF00069	0.778
MOD_ProDKin_1	49	55	PF00069	0.791
MOD_ProDKin_1	92	98	PF00069	0.776
MOD_SUMO_for_1	392	395	PF00179	0.803
MOD_SUMO_for_1	558	561	PF00179	0.840
TRG_DiLeu_BaLyEn_6	457	462	PF01217	0.605
TRG_ENDOCYTIC_2	405	408	PF00928	0.791
TRG_ENDOCYTIC_2	441	444	PF00928	0.815
TRG_ER_diArg_1	35	37	PF00400	0.827
TRG_ER_diArg_1	369	372	PF00400	0.609
TRG_ER_diArg_1	590	592	PF00400	0.741

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HN92	Leishmania braziliensis	54%	100%
A4IBW2	Leishmania infantum	99%	100%
E9AFP9	Leishmania major	85%	100%
E9B6V2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	99%