C2H2 type zinc-finger (2 copies), putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

C2H2 type zinc-finger (2 copies), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJF7_LEIDO

TriTrypDb:

LdBPK_301970.1 , LdCL_300025000 , LDHU3_30.2700

Length:

341

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJF7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJF7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	164	168	PF00656	0.623
CLV_C14_Caspase3-7	279	283	PF00656	0.399
CLV_C14_Caspase3-7	90	94	PF00656	0.408
CLV_MEL_PAP_1	274	280	PF00089	0.490
CLV_NRD_NRD_1	218	220	PF00675	0.295
CLV_NRD_NRD_1	236	238	PF00675	0.140
CLV_NRD_NRD_1	276	278	PF00675	0.419
CLV_PCSK_KEX2_1	218	220	PF00082	0.305
CLV_PCSK_KEX2_1	236	238	PF00082	0.305
CLV_PCSK_KEX2_1	276	278	PF00082	0.419
CLV_PCSK_SKI1_1	10	14	PF00082	0.414
CLV_PCSK_SKI1_1	259	263	PF00082	0.309
DEG_COP1_1	309	321	PF00400	0.511
DOC_USP7_MATH_1	238	242	PF00917	0.524
DOC_USP7_MATH_1	326	330	PF00917	0.504
DOC_USP7_MATH_1	91	95	PF00917	0.423
DOC_USP7_UBL2_3	6	10	PF12436	0.484
DOC_WW_Pin1_4	147	152	PF00397	0.562
DOC_WW_Pin1_4	74	79	PF00397	0.438
LIG_14-3-3_CanoR_1	213	217	PF00244	0.454
LIG_14-3-3_CanoR_1	237	246	PF00244	0.454
LIG_14-3-3_CanoR_1	276	286	PF00244	0.502
LIG_14-3-3_CanoR_1	330	338	PF00244	0.525
LIG_APCC_ABBA_1	189	194	PF00400	0.377
LIG_APCC_ABBAyCdc20_2	219	225	PF00400	0.454
LIG_FHA_1	333	339	PF00498	0.488
LIG_FHA_2	164	170	PF00498	0.611
LIG_FHA_2	298	304	PF00498	0.469
LIG_FHA_2	318	324	PF00498	0.467
LIG_FHA_2	88	94	PF00498	0.564
LIG_Integrin_RGD_1	158	160	PF01839	0.610
LIG_LIR_Gen_1	167	178	PF02991	0.635
LIG_LIR_Gen_1	224	234	PF02991	0.423
LIG_LIR_Gen_1	292	299	PF02991	0.444
LIG_LIR_Nem_3	167	173	PF02991	0.575
LIG_LIR_Nem_3	224	229	PF02991	0.434
LIG_LIR_Nem_3	23	27	PF02991	0.354
LIG_LIR_Nem_3	312	318	PF02991	0.452
LIG_NRBOX	66	72	PF00104	0.440
LIG_PCNA_PIPBox_1	36	45	PF02747	0.440
LIG_SH2_CRK	226	230	PF00017	0.432
LIG_SH2_STAT5	192	195	PF00017	0.465
LIG_SH3_3	126	132	PF00018	0.624
LIG_SH3_3	145	151	PF00018	0.451
LIG_SH3_3	284	290	PF00018	0.419
LIG_SH3_3	310	316	PF00018	0.504
LIG_SH3_3	55	61	PF00018	0.454
LIG_SH3_3	72	78	PF00018	0.344
LIG_TRAF2_1	161	164	PF00917	0.703
LIG_TRAF2_1	308	311	PF00917	0.596
LIG_TRAF2_1	320	323	PF00917	0.490
MOD_CK1_1	127	133	PF00069	0.649
MOD_CK1_1	73	79	PF00069	0.490
MOD_CK1_1	94	100	PF00069	0.444
MOD_CK2_1	163	169	PF00069	0.555
MOD_CK2_1	297	303	PF00069	0.527
MOD_CK2_1	317	323	PF00069	0.452
MOD_GlcNHglycan	126	129	PF01048	0.576
MOD_GlcNHglycan	194	198	PF01048	0.330
MOD_GlcNHglycan	300	303	PF01048	0.474
MOD_GlcNHglycan	93	96	PF01048	0.287
MOD_GSK3_1	142	149	PF00069	0.608
MOD_GSK3_1	293	300	PF00069	0.453
MOD_GSK3_1	332	339	PF00069	0.558
MOD_GSK3_1	66	73	PF00069	0.463
MOD_GSK3_1	87	94	PF00069	0.520
MOD_NEK2_1	137	142	PF00069	0.657
MOD_NEK2_1	212	217	PF00069	0.454
MOD_NEK2_1	297	302	PF00069	0.396
MOD_NEK2_1	5	10	PF00069	0.428
MOD_NEK2_1	70	75	PF00069	0.524
MOD_PIKK_1	27	33	PF00454	0.423
MOD_PKA_1	276	282	PF00069	0.426
MOD_PKA_2	212	218	PF00069	0.454
MOD_PKA_2	276	282	PF00069	0.509
MOD_Plk_2-3	163	169	PF00069	0.759
MOD_Plk_4	212	218	PF00069	0.513
MOD_Plk_4	66	72	PF00069	0.451
MOD_Plk_4	94	100	PF00069	0.452
MOD_ProDKin_1	147	153	PF00069	0.563
MOD_ProDKin_1	74	80	PF00069	0.438
TRG_DiLeu_BaLyEn_6	59	64	PF01217	0.431
TRG_ENDOCYTIC_2	226	229	PF00928	0.433
TRG_ER_diArg_1	217	219	PF00400	0.507
TRG_ER_diArg_1	235	237	PF00400	0.484
TRG_ER_diArg_1	275	277	PF00400	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8N5	Leptomonas seymouri	55%	100%
A0A0S4JM68	Bodo saltans	30%	100%
A0A422P3H1	Trypanosoma rangeli	36%	100%
A4HID1	Leishmania braziliensis	78%	100%
A4I5M4	Leishmania infantum	99%	100%
C9ZQZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9B0W9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q797	Leishmania major	95%	100%
Q9W1V7	Drosophila melanogaster	25%	75%
V5BYU5	Trypanosoma cruzi	38%	100%