Zinc finger, C3HC4 type (RING finger) containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Zinc finger, C3HC4 type (RING finger), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJF1_LEIDO

TriTrypDb:

LdBPK_364020.1 , LdCL_360047200 , LDHU3_36.5390

Length:

312

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJF1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJF1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	23	25	PF00675	0.659
CLV_PCSK_KEX2_1	23	25	PF00082	0.659
CLV_PCSK_KEX2_1	293	295	PF00082	0.417
CLV_PCSK_PC1ET2_1	293	295	PF00082	0.399
CLV_PCSK_SKI1_1	76	80	PF00082	0.548
DEG_APCC_DBOX_1	148	156	PF00400	0.440
DEG_SCF_FBW7_1	239	245	PF00400	0.519
DOC_CKS1_1	239	244	PF01111	0.614
DOC_MAPK_gen_1	293	301	PF00069	0.334
DOC_MAPK_MEF2A_6	270	279	PF00069	0.281
DOC_PP2B_LxvP_1	171	174	PF13499	0.485
DOC_USP7_MATH_1	216	220	PF00917	0.673
DOC_USP7_MATH_1	257	261	PF00917	0.596
DOC_USP7_MATH_1	93	97	PF00917	0.677
DOC_USP7_UBL2_3	42	46	PF12436	0.619
DOC_WW_Pin1_4	153	158	PF00397	0.618
DOC_WW_Pin1_4	16	21	PF00397	0.626
DOC_WW_Pin1_4	230	235	PF00397	0.730
DOC_WW_Pin1_4	238	243	PF00397	0.673
LIG_14-3-3_CanoR_1	117	122	PF00244	0.403
LIG_14-3-3_CanoR_1	15	20	PF00244	0.710
LIG_14-3-3_CanoR_1	23	29	PF00244	0.591
LIG_14-3-3_CanoR_1	259	266	PF00244	0.590
LIG_14-3-3_CanoR_1	294	298	PF00244	0.305
LIG_BRCT_BRCA1_1	119	123	PF00533	0.399
LIG_BRCT_BRCA1_1	95	99	PF00533	0.641
LIG_Clathr_ClatBox_1	112	116	PF01394	0.399
LIG_DLG_GKlike_1	117	124	PF00625	0.324
LIG_FHA_1	134	140	PF00498	0.393
LIG_FHA_1	206	212	PF00498	0.598
LIG_FHA_1	256	262	PF00498	0.597
LIG_FHA_1	294	300	PF00498	0.307
LIG_FHA_1	45	51	PF00498	0.540
LIG_FHA_1	70	76	PF00498	0.491
LIG_FHA_2	173	179	PF00498	0.479
LIG_FHA_2	189	195	PF00498	0.437
LIG_FHA_2	239	245	PF00498	0.707
LIG_FHA_2	59	65	PF00498	0.566
LIG_LIR_Gen_1	120	129	PF02991	0.480
LIG_LIR_Nem_3	120	124	PF02991	0.480
LIG_LIR_Nem_3	271	275	PF02991	0.351
LIG_SH2_CRK	121	125	PF00017	0.307
LIG_SH2_CRK	272	276	PF00017	0.417
LIG_SH2_STAT5	288	291	PF00017	0.378
LIG_SH2_STAT5	49	52	PF00017	0.547
LIG_SH3_3	206	212	PF00018	0.549
LIG_SH3_3	236	242	PF00018	0.674
LIG_SH3_3	274	280	PF00018	0.373
MOD_CDK_SPxxK_3	16	23	PF00069	0.692
MOD_CK1_1	225	231	PF00069	0.721
MOD_CK1_1	245	251	PF00069	0.449
MOD_CK2_1	188	194	PF00069	0.533
MOD_CK2_1	23	29	PF00069	0.773
MOD_GlcNHglycan	104	107	PF01048	0.561
MOD_GlcNHglycan	217	221	PF01048	0.707
MOD_GlcNHglycan	247	250	PF01048	0.678
MOD_GlcNHglycan	95	98	PF01048	0.693
MOD_GSK3_1	153	160	PF00069	0.497
MOD_GSK3_1	218	225	PF00069	0.641
MOD_GSK3_1	238	245	PF00069	0.520
MOD_GSK3_1	255	262	PF00069	0.554
MOD_GSK3_1	288	295	PF00069	0.357
MOD_N-GLC_1	157	162	PF02516	0.554
MOD_N-GLC_1	223	228	PF02516	0.629
MOD_NEK2_1	286	291	PF00069	0.417
MOD_NMyristoyl	1	7	PF02799	0.549
MOD_OFUCOSY	126	131	PF10250	0.346
MOD_OFUCOSY	290	297	PF10250	0.288
MOD_PIKK_1	188	194	PF00454	0.467
MOD_PIKK_1	288	294	PF00454	0.300
MOD_PK_1	24	30	PF00069	0.653
MOD_PKA_1	23	29	PF00069	0.657
MOD_PKA_1	293	299	PF00069	0.417
MOD_PKA_2	188	194	PF00069	0.467
MOD_PKA_2	23	29	PF00069	0.639
MOD_PKA_2	293	299	PF00069	0.306
MOD_Plk_2-3	29	35	PF00069	0.647
MOD_Plk_4	172	178	PF00069	0.470
MOD_Plk_4	242	248	PF00069	0.512
MOD_Plk_4	58	64	PF00069	0.433
MOD_ProDKin_1	153	159	PF00069	0.618
MOD_ProDKin_1	16	22	PF00069	0.627
MOD_ProDKin_1	230	236	PF00069	0.733
MOD_ProDKin_1	238	244	PF00069	0.673
TRG_ENDOCYTIC_2	121	124	PF00928	0.308
TRG_ENDOCYTIC_2	272	275	PF00928	0.417
TRG_ER_diArg_1	186	189	PF00400	0.563
TRG_ER_diArg_1	23	25	PF00400	0.660
TRG_Pf-PMV_PEXEL_1	48	52	PF00026	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYK3	Leptomonas seymouri	56%	98%
A0A0S4JLL7	Bodo saltans	33%	100%
A0A1X0P3L1	Trypanosomatidae	40%	100%
A4HPQ0	Leishmania braziliensis	78%	100%
A4ID13	Leishmania infantum	100%	100%
D0A8G4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9ATG5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q132	Leishmania major	95%	100%
V5BIP2	Trypanosoma cruzi	32%	100%