LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IJD6_LEIDO
TriTrypDb:
LdBPK_353940.1 , LdCL_350044500 , LDHU3_35.5110
Length:
341

Annotations

LeishMANIAdb annotations

A conserved tail-anchored protein of unclear function. Kinetoplastid-specicic protein

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 2
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Expansion

Sequence features

A0A3Q8IJD6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJD6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_MEL_PAP_1 216 222 PF00089 0.445
CLV_NRD_NRD_1 160 162 PF00675 0.495
CLV_NRD_NRD_1 238 240 PF00675 0.410
CLV_NRD_NRD_1 321 323 PF00675 0.417
CLV_PCSK_KEX2_1 100 102 PF00082 0.407
CLV_PCSK_KEX2_1 160 162 PF00082 0.488
CLV_PCSK_KEX2_1 238 240 PF00082 0.393
CLV_PCSK_KEX2_1 321 323 PF00082 0.381
CLV_PCSK_KEX2_1 70 72 PF00082 0.393
CLV_PCSK_KEX2_1 75 77 PF00082 0.425
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HTX3 Leptomonas seymouri 75% 95%
A0A0S4J079 Bodo saltans 49% 95%
A0A1X0P567 Trypanosomatidae 58% 96%
A0A422N430 Trypanosoma rangeli 55% 96%
A4HN61 Leishmania braziliensis 87% 100%
A4IBS8 Leishmania infantum 100% 100%
C9ZYU4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 51% 96%
E9AFL4 Leishmania major 96% 100%
E9B6R8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
V5BCU0 Trypanosoma cruzi 56% 96%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS