Phenazine biosynthesis-like protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Phenazine biosynthesis-like protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IJD5_LEIDO

TriTrypDb:

LdBPK_170540.1 , LdCL_170010800 , LDHU3_17.0830

Length:

533

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IJD5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJD5

Function

Biological processes
Term	Name	Level	Count
GO:0008152	metabolic process	1	7
GO:0009058	biosynthetic process	2	7

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7
GO:0016853	isomerase activity	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	141	143	PF00675	0.603
CLV_NRD_NRD_1	226	228	PF00675	0.705
CLV_NRD_NRD_1	229	231	PF00675	0.592
CLV_NRD_NRD_1	305	307	PF00675	0.389
CLV_NRD_NRD_1	399	401	PF00675	0.513
CLV_NRD_NRD_1	505	507	PF00675	0.411
CLV_NRD_NRD_1	61	63	PF00675	0.707
CLV_PCSK_FUR_1	227	231	PF00082	0.635
CLV_PCSK_KEX2_1	140	142	PF00082	0.570
CLV_PCSK_KEX2_1	226	228	PF00082	0.705
CLV_PCSK_KEX2_1	229	231	PF00082	0.592
CLV_PCSK_KEX2_1	305	307	PF00082	0.389
CLV_PCSK_KEX2_1	399	401	PF00082	0.513
CLV_PCSK_KEX2_1	494	496	PF00082	0.411
CLV_PCSK_PC1ET2_1	494	496	PF00082	0.411
CLV_PCSK_SKI1_1	239	243	PF00082	0.411
CLV_PCSK_SKI1_1	399	403	PF00082	0.416
CLV_PCSK_SKI1_1	510	514	PF00082	0.411
CLV_PCSK_SKI1_1	62	66	PF00082	0.758
CLV_PCSK_SKI1_1	80	84	PF00082	0.434
DEG_Nend_UBRbox_2	1	3	PF02207	0.659
DEG_SPOP_SBC_1	401	405	PF00917	0.436
DOC_CKS1_1	240	245	PF01111	0.411
DOC_CKS1_1	382	387	PF01111	0.389
DOC_CKS1_1	8	13	PF01111	0.592
DOC_MAPK_gen_1	480	489	PF00069	0.338
DOC_MAPK_gen_1	506	513	PF00069	0.411
DOC_PP2B_LxvP_1	156	159	PF13499	0.712
DOC_PP4_FxxP_1	284	287	PF00568	0.411
DOC_PP4_FxxP_1	448	451	PF00568	0.411
DOC_SPAK_OSR1_1	480	484	PF12202	0.338
DOC_USP7_MATH_1	176	180	PF00917	0.791
DOC_USP7_MATH_1	196	200	PF00917	0.689
DOC_USP7_MATH_1	214	218	PF00917	0.692
DOC_USP7_MATH_1	401	405	PF00917	0.430
DOC_USP7_MATH_1	44	48	PF00917	0.633
DOC_USP7_UBL2_3	20	24	PF12436	0.418
DOC_USP7_UBL2_3	63	67	PF12436	0.749
DOC_WW_Pin1_4	188	193	PF00397	0.777
DOC_WW_Pin1_4	239	244	PF00397	0.411
DOC_WW_Pin1_4	322	327	PF00397	0.389
DOC_WW_Pin1_4	381	386	PF00397	0.389
DOC_WW_Pin1_4	7	12	PF00397	0.511
LIG_14-3-3_CanoR_1	161	167	PF00244	0.816
LIG_14-3-3_CanoR_1	213	219	PF00244	0.674
LIG_14-3-3_CanoR_1	229	238	PF00244	0.389
LIG_14-3-3_CanoR_1	266	276	PF00244	0.411
LIG_14-3-3_CanoR_1	381	385	PF00244	0.411
LIG_14-3-3_CanoR_1	399	408	PF00244	0.411
LIG_14-3-3_CanoR_1	522	528	PF00244	0.619
LIG_BRCT_BRCA1_1	196	200	PF00533	0.689
LIG_BRCT_BRCA1_1	403	407	PF00533	0.411
LIG_BRCT_BRCA1_1	445	449	PF00533	0.411
LIG_CSL_BTD_1	187	190	PF09270	0.632
LIG_deltaCOP1_diTrp_1	394	402	PF00928	0.436
LIG_EH1_1	261	269	PF00400	0.513
LIG_FHA_1	271	277	PF00498	0.403
LIG_FHA_1	288	294	PF00498	0.397
LIG_FHA_1	326	332	PF00498	0.436
LIG_FHA_1	334	340	PF00498	0.334
LIG_FHA_1	459	465	PF00498	0.411
LIG_FHA_1	498	504	PF00498	0.411
LIG_FHA_1	524	530	PF00498	0.640
LIG_FHA_1	98	104	PF00498	0.477
LIG_FHA_2	111	117	PF00498	0.650
LIG_FHA_2	146	152	PF00498	0.681
LIG_FHA_2	218	224	PF00498	0.747
LIG_FHA_2	63	69	PF00498	0.638
LIG_Integrin_isoDGR_2	478	480	PF01839	0.338
LIG_LIR_Apic_2	283	287	PF02991	0.411
LIG_LIR_Apic_2	446	451	PF02991	0.411
LIG_LIR_Gen_1	368	379	PF02991	0.436
LIG_LIR_Gen_1	394	402	PF02991	0.436
LIG_LIR_Gen_1	41	50	PF02991	0.629
LIG_LIR_Nem_3	233	238	PF02991	0.389
LIG_LIR_Nem_3	348	353	PF02991	0.383
LIG_LIR_Nem_3	368	374	PF02991	0.280
LIG_LIR_Nem_3	394	398	PF02991	0.436
LIG_LIR_Nem_3	41	45	PF02991	0.617
LIG_MLH1_MIPbox_1	445	449	PF16413	0.411
LIG_MYND_1	192	196	PF01753	0.695
LIG_Pex14_2	236	240	PF04695	0.411
LIG_Pex14_2	448	452	PF04695	0.411
LIG_PTB_Apo_2	475	482	PF02174	0.338
LIG_SH2_CRK	104	108	PF00017	0.521
LIG_SH2_CRK	371	375	PF00017	0.436
LIG_SH2_NCK_1	211	215	PF00017	0.766
LIG_SH2_STAP1	129	133	PF00017	0.594
LIG_SH2_STAP1	329	333	PF00017	0.411
LIG_SH2_STAT5	211	214	PF00017	0.690
LIG_SH2_STAT5	322	325	PF00017	0.513
LIG_SH2_STAT5	378	381	PF00017	0.411
LIG_SH2_STAT5	38	41	PF00017	0.530
LIG_SH3_3	151	157	PF00018	0.647
LIG_SH3_3	186	192	PF00018	0.702
LIG_SH3_3	328	334	PF00018	0.411
LIG_SH3_3	414	420	PF00018	0.375
LIG_SH3_3	5	11	PF00018	0.637
LIG_SUMO_SIM_anti_2	509	515	PF11976	0.411
LIG_TYR_ITIM	369	374	PF00017	0.436
LIG_WRC_WIRS_1	517	522	PF05994	0.402
MOD_CDK_SPxK_1	239	245	PF00069	0.411
MOD_CK1_1	198	204	PF00069	0.685
MOD_CK1_1	205	211	PF00069	0.639
MOD_CK1_1	217	223	PF00069	0.718
MOD_CK1_1	270	276	PF00069	0.411
MOD_CK1_1	325	331	PF00069	0.402
MOD_CK1_1	372	378	PF00069	0.513
MOD_CK1_1	43	49	PF00069	0.640
MOD_CK1_1	463	469	PF00069	0.436
MOD_CK2_1	110	116	PF00069	0.648
MOD_CK2_1	217	223	PF00069	0.742
MOD_CK2_1	337	343	PF00069	0.327
MOD_CK2_1	43	49	PF00069	0.640
MOD_Cter_Amidation	224	227	PF01082	0.745
MOD_Cter_Amidation	504	507	PF01082	0.411
MOD_GlcNHglycan	143	146	PF01048	0.657
MOD_GlcNHglycan	178	181	PF01048	0.791
MOD_GlcNHglycan	204	207	PF01048	0.743
MOD_GlcNHglycan	298	301	PF01048	0.389
MOD_GlcNHglycan	41	45	PF01048	0.617
MOD_GlcNHglycan	413	417	PF01048	0.524
MOD_GSK3_1	106	113	PF00069	0.545
MOD_GSK3_1	141	148	PF00069	0.640
MOD_GSK3_1	162	169	PF00069	0.786
MOD_GSK3_1	170	177	PF00069	0.699
MOD_GSK3_1	194	201	PF00069	0.672
MOD_GSK3_1	2	9	PF00069	0.504
MOD_GSK3_1	205	212	PF00069	0.640
MOD_GSK3_1	214	221	PF00069	0.475
MOD_GSK3_1	296	303	PF00069	0.343
MOD_GSK3_1	318	325	PF00069	0.400
MOD_GSK3_1	333	340	PF00069	0.407
MOD_GSK3_1	40	47	PF00069	0.608
MOD_GSK3_1	460	467	PF00069	0.299
MOD_N-GLC_1	523	528	PF02516	0.525
MOD_N-GLC_1	95	100	PF02516	0.510
MOD_NEK2_1	170	175	PF00069	0.662
MOD_NEK2_1	202	207	PF00069	0.682
MOD_NEK2_1	209	214	PF00069	0.630
MOD_NEK2_1	262	267	PF00069	0.513
MOD_NEK2_1	318	323	PF00069	0.403
MOD_NEK2_1	40	45	PF00069	0.607
MOD_NEK2_1	402	407	PF00069	0.327
MOD_NEK2_1	424	429	PF00069	0.411
MOD_NEK2_1	464	469	PF00069	0.299
MOD_NEK2_1	48	53	PF00069	0.672
MOD_NEK2_1	97	102	PF00069	0.485
MOD_NEK2_2	300	305	PF00069	0.411
MOD_PIKK_1	170	176	PF00454	0.753
MOD_PIKK_1	230	236	PF00454	0.389
MOD_PIKK_1	56	62	PF00454	0.579
MOD_PK_1	307	313	PF00069	0.397
MOD_PKA_1	141	147	PF00069	0.587
MOD_PKA_1	305	311	PF00069	0.389
MOD_PKA_1	62	68	PF00069	0.674
MOD_PKA_2	141	147	PF00069	0.587
MOD_PKA_2	212	218	PF00069	0.685
MOD_PKA_2	305	311	PF00069	0.389
MOD_PKA_2	380	386	PF00069	0.411
MOD_Plk_1	262	268	PF00069	0.411
MOD_Plk_1	40	46	PF00069	0.604
MOD_Plk_1	412	418	PF00069	0.521
MOD_Plk_1	48	54	PF00069	0.679
MOD_Plk_1	523	529	PF00069	0.527
MOD_Plk_2-3	337	343	PF00069	0.383
MOD_Plk_2-3	74	80	PF00069	0.598
MOD_Plk_4	205	211	PF00069	0.635
MOD_Plk_4	214	220	PF00069	0.709
MOD_Plk_4	313	319	PF00069	0.343
MOD_Plk_4	33	39	PF00069	0.493
MOD_Plk_4	464	470	PF00069	0.379
MOD_Plk_4	516	522	PF00069	0.411
MOD_ProDKin_1	188	194	PF00069	0.778
MOD_ProDKin_1	239	245	PF00069	0.411
MOD_ProDKin_1	322	328	PF00069	0.389
MOD_ProDKin_1	381	387	PF00069	0.389
MOD_ProDKin_1	7	13	PF00069	0.504
MOD_SUMO_rev_2	124	133	PF00179	0.563
MOD_SUMO_rev_2	56	65	PF00179	0.782
TRG_DiLeu_BaEn_1	263	268	PF01217	0.513
TRG_DiLeu_BaEn_1	509	514	PF01217	0.411
TRG_ENDOCYTIC_2	371	374	PF00928	0.418
TRG_ER_diArg_1	140	142	PF00400	0.570
TRG_ER_diArg_1	226	229	PF00400	0.679
TRG_ER_diArg_1	304	306	PF00400	0.389
TRG_ER_diArg_1	398	400	PF00400	0.513
TRG_Pf-PMV_PEXEL_1	112	116	PF00026	0.551

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCR2	Leptomonas seymouri	68%	100%
A4H8Z1	Leishmania braziliensis	79%	100%
A4HXC2	Leishmania infantum	99%	100%
E9AR17	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QEE6	Leishmania major	94%	100%