Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IJB3_LEIDO

TriTrypDb:

LdBPK_322100.1 , LdCL_320026400 , LDHU3_32.2610

Length:

148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJB3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJB3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	62	66	PF00656	0.716
CLV_NRD_NRD_1	103	105	PF00675	0.469
CLV_NRD_NRD_1	145	147	PF00675	0.549
CLV_NRD_NRD_1	30	32	PF00675	0.597
CLV_NRD_NRD_1	60	62	PF00675	0.640
CLV_PCSK_FUR_1	6	10	PF00082	0.466
CLV_PCSK_KEX2_1	102	104	PF00082	0.606
CLV_PCSK_KEX2_1	144	146	PF00082	0.541
CLV_PCSK_KEX2_1	29	31	PF00082	0.503
CLV_PCSK_KEX2_1	34	36	PF00082	0.564
CLV_PCSK_KEX2_1	59	61	PF00082	0.627
CLV_PCSK_KEX2_1	8	10	PF00082	0.466
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.606
CLV_PCSK_PC1ET2_1	144	146	PF00082	0.565
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.503
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.564
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.579
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.466
CLV_PCSK_PC7_1	30	36	PF00082	0.538
CLV_PCSK_SKI1_1	141	145	PF00082	0.614
DEG_SPOP_SBC_1	134	138	PF00917	0.488
DOC_USP7_MATH_1	64	68	PF00917	0.657
DOC_USP7_UBL2_3	140	144	PF12436	0.570
DOC_USP7_UBL2_3	4	8	PF12436	0.469
LIG_14-3-3_CanoR_1	103	111	PF00244	0.553
LIG_BIR_III_2	126	130	PF00653	0.595
LIG_FHA_1	130	136	PF00498	0.557
LIG_FHA_2	37	43	PF00498	0.639
LIG_FHA_2	60	66	PF00498	0.587
LIG_LIR_Gen_1	108	117	PF02991	0.559
LIG_LIR_Nem_3	108	114	PF02991	0.499
LIG_SH2_STAT5	12	15	PF00017	0.446
LIG_SH2_STAT5	26	29	PF00017	0.468
MOD_CK1_1	105	111	PF00069	0.619
MOD_CK1_1	118	124	PF00069	0.657
MOD_CK1_1	133	139	PF00069	0.485
MOD_CK1_1	36	42	PF00069	0.648
MOD_CK1_1	85	91	PF00069	0.576
MOD_CK2_1	107	113	PF00069	0.567
MOD_CK2_1	36	42	PF00069	0.629
MOD_GlcNHglycan	131	135	PF01048	0.610
MOD_GlcNHglycan	70	73	PF01048	0.685
MOD_GlcNHglycan	88	91	PF01048	0.524
MOD_GSK3_1	118	125	PF00069	0.634
MOD_GSK3_1	129	136	PF00069	0.670
MOD_GSK3_1	64	71	PF00069	0.591
MOD_GSK3_1	82	89	PF00069	0.635
MOD_NEK2_1	84	89	PF00069	0.526
MOD_NEK2_2	139	144	PF00069	0.573
MOD_PKA_1	102	108	PF00069	0.539
MOD_PKA_1	59	65	PF00069	0.623
MOD_PKA_2	102	108	PF00069	0.572
MOD_PKA_2	129	135	PF00069	0.561
MOD_PKA_2	22	28	PF00069	0.514
MOD_PKA_2	36	42	PF00069	0.634
MOD_PKA_2	59	65	PF00069	0.623
MOD_Plk_1	130	136	PF00069	0.579
MOD_Plk_4	22	28	PF00069	0.514
TRG_NLS_MonoCore_2	57	62	PF00514	0.637
TRG_NLS_MonoExtC_3	57	63	PF00514	0.636
TRG_NLS_MonoExtN_4	100	106	PF00514	0.476
TRG_NLS_MonoExtN_4	141	148	PF00514	0.576
TRG_NLS_MonoExtN_4	2	7	PF00514	0.495
TRG_NLS_MonoExtN_4	57	62	PF00514	0.621
TRG_Pf-PMV_PEXEL_1	17	22	PF00026	0.472

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXV1	Leptomonas seymouri	49%	100%
A0A422NBB5	Trypanosoma rangeli	45%	100%
A4HKI7	Leishmania braziliensis	68%	100%
A4I819	Leishmania infantum	100%	100%
E9B2X7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q579	Leishmania major	87%	100%