LeishMANIAdb
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Ubiquitin hydrolase, putative

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Ubiquitin hydrolase, putative
Gene product:
ubiquitin hydrolase, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IJ46_LEIDO
TriTrypDb:
LdBPK_300250.1 , LdCL_300007600 , LDHU3_30.0390
Length:
1132

Annotations

Annotations by Jardim et al.

Protein modification, ubiquitin hydrolase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0000932 P-body 5 1
GO:0031251 PAN complex 2 1
GO:0032991 protein-containing complex 1 1
GO:0035770 ribonucleoprotein granule 3 1
GO:0036464 cytoplasmic ribonucleoprotein granule 4 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0099080 supramolecular complex 2 1
GO:0110165 cellular anatomical entity 1 1

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A0A3Q8IJ46
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJ46

Function

Biological processes
Term Name Level Count
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 8 1
GO:0000956 nuclear-transcribed mRNA catabolic process 7 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006401 RNA catabolic process 5 1
GO:0006402 mRNA catabolic process 6 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009056 catabolic process 2 1
GO:0009057 macromolecule catabolic process 4 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0009987 cellular process 1 1
GO:0010468 regulation of gene expression 5 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0010629 negative regulation of gene expression 6 1
GO:0016070 RNA metabolic process 5 1
GO:0016071 mRNA metabolic process 6 1
GO:0019222 regulation of metabolic process 3 1
GO:0019439 aromatic compound catabolic process 4 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034655 nucleobase-containing compound catabolic process 4 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044248 cellular catabolic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044265 obsolete cellular macromolecule catabolic process 4 1
GO:0044270 cellular nitrogen compound catabolic process 4 1
GO:0046483 heterocycle metabolic process 3 1
GO:0046700 heterocycle catabolic process 4 1
GO:0048519 negative regulation of biological process 3 1
GO:0050789 regulation of biological process 2 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071704 organic substance metabolic process 2 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1901361 organic cyclic compound catabolic process 4 1
GO:1901575 organic substance catabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 11
GO:0003824 catalytic activity 1 11
GO:0004518 nuclease activity 4 11
GO:0004527 exonuclease activity 5 11
GO:0005488 binding 1 11
GO:0016787 hydrolase activity 2 11
GO:0016788 hydrolase activity, acting on ester bonds 3 11
GO:0097159 organic cyclic compound binding 2 11
GO:1901363 heterocyclic compound binding 2 11
GO:0000175 3'-5'-RNA exonuclease activity 7 1
GO:0004532 RNA exonuclease activity 5 1
GO:0004535 poly(A)-specific ribonuclease activity 8 1
GO:0004540 RNA nuclease activity 4 1
GO:0008408 3'-5' exonuclease activity 6 1
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 1
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6 1
GO:0140098 catalytic activity, acting on RNA 3 1
GO:0140640 catalytic activity, acting on a nucleic acid 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 886 890 PF00656 0.442
CLV_NRD_NRD_1 1018 1020 PF00675 0.307
CLV_NRD_NRD_1 1126 1128 PF00675 0.557
CLV_NRD_NRD_1 228 230 PF00675 0.330
CLV_NRD_NRD_1 250 252 PF00675 0.308
CLV_NRD_NRD_1 441 443 PF00675 0.481
CLV_NRD_NRD_1 446 448 PF00675 0.459
CLV_NRD_NRD_1 517 519 PF00675 0.189
CLV_NRD_NRD_1 871 873 PF00675 0.553
CLV_NRD_NRD_1 967 969 PF00675 0.281
CLV_PCSK_KEX2_1 100 102 PF00082 0.339
CLV_PCSK_KEX2_1 250 252 PF00082 0.308
CLV_PCSK_KEX2_1 446 448 PF00082 0.455
CLV_PCSK_KEX2_1 527 529 PF00082 0.249
CLV_PCSK_KEX2_1 684 686 PF00082 0.349
CLV_PCSK_PC1ET2_1 100 102 PF00082 0.318
CLV_PCSK_PC1ET2_1 446 448 PF00082 0.455
CLV_PCSK_PC1ET2_1 527 529 PF00082 0.288
CLV_PCSK_PC1ET2_1 684 686 PF00082 0.321
CLV_PCSK_PC7_1 442 448 PF00082 0.574
CLV_PCSK_PC7_1 523 529 PF00082 0.281
CLV_PCSK_SKI1_1 1052 1056 PF00082 0.530
CLV_PCSK_SKI1_1 1074 1078 PF00082 0.605
CLV_PCSK_SKI1_1 141 145 PF00082 0.419
CLV_PCSK_SKI1_1 217 221 PF00082 0.389
CLV_PCSK_SKI1_1 262 266 PF00082 0.399
CLV_PCSK_SKI1_1 280 284 PF00082 0.477
CLV_PCSK_SKI1_1 443 447 PF00082 0.577
CLV_PCSK_SKI1_1 519 523 PF00082 0.201
CLV_PCSK_SKI1_1 601 605 PF00082 0.281
CLV_PCSK_SKI1_1 72 76 PF00082 0.409
CLV_PCSK_SKI1_1 819 823 PF00082 0.495
CLV_PCSK_SKI1_1 827 831 PF00082 0.489
CLV_PCSK_SKI1_1 86 90 PF00082 0.188
CLV_PCSK_SKI1_1 928 932 PF00082 0.187
DEG_APCC_DBOX_1 600 608 PF00400 0.481
DEG_SCF_FBW7_1 1059 1065 PF00400 0.655
DEG_SPOP_SBC_1 282 286 PF00917 0.431
DOC_ANK_TNKS_1 940 947 PF00023 0.481
DOC_CKS1_1 1059 1064 PF01111 0.615
DOC_CKS1_1 192 197 PF01111 0.431
DOC_CKS1_1 499 504 PF01111 0.481
DOC_CKS1_1 788 793 PF01111 0.428
DOC_CYCLIN_RxL_1 816 824 PF00134 0.458
DOC_CYCLIN_yClb5_NLxxxL_5 800 808 PF00134 0.445
DOC_CYCLIN_yCln2_LP_2 152 158 PF00134 0.368
DOC_CYCLIN_yCln2_LP_2 265 271 PF00134 0.397
DOC_CYCLIN_yCln2_LP_2 417 423 PF00134 0.481
DOC_MAPK_DCC_7 554 564 PF00069 0.481
DOC_MAPK_DCC_7 684 692 PF00069 0.303
DOC_MAPK_gen_1 197 205 PF00069 0.505
DOC_MAPK_gen_1 684 692 PF00069 0.287
DOC_MAPK_gen_1 872 878 PF00069 0.402
DOC_MAPK_HePTP_8 681 693 PF00069 0.425
DOC_MAPK_MEF2A_6 197 205 PF00069 0.390
DOC_MAPK_MEF2A_6 684 693 PF00069 0.283
DOC_PP1_RVXF_1 473 479 PF00149 0.511
DOC_PP2B_LxvP_1 152 155 PF13499 0.450
DOC_PP2B_LxvP_1 376 379 PF13499 0.511
DOC_PP2B_LxvP_1 701 704 PF13499 0.346
DOC_PP4_FxxP_1 331 334 PF00568 0.428
DOC_PP4_FxxP_1 583 586 PF00568 0.481
DOC_PP4_FxxP_1 830 833 PF00568 0.339
DOC_PP4_FxxP_1 978 981 PF00568 0.387
DOC_USP7_MATH_1 1011 1015 PF00917 0.387
DOC_USP7_MATH_1 1042 1046 PF00917 0.392
DOC_USP7_MATH_1 1117 1121 PF00917 0.576
DOC_USP7_MATH_1 17 21 PF00917 0.418
DOC_USP7_MATH_1 171 175 PF00917 0.408
DOC_USP7_MATH_1 193 197 PF00917 0.437
DOC_USP7_MATH_1 696 700 PF00917 0.510
DOC_USP7_MATH_1 772 776 PF00917 0.380
DOC_USP7_MATH_1 833 837 PF00917 0.325
DOC_USP7_MATH_1 879 883 PF00917 0.464
DOC_USP7_MATH_1 923 927 PF00917 0.387
DOC_USP7_UBL2_3 446 450 PF12436 0.496
DOC_WW_Pin1_4 1055 1060 PF00397 0.523
DOC_WW_Pin1_4 1066 1071 PF00397 0.517
DOC_WW_Pin1_4 191 196 PF00397 0.472
DOC_WW_Pin1_4 264 269 PF00397 0.349
DOC_WW_Pin1_4 283 288 PF00397 0.265
DOC_WW_Pin1_4 296 301 PF00397 0.279
DOC_WW_Pin1_4 457 462 PF00397 0.607
DOC_WW_Pin1_4 498 503 PF00397 0.481
DOC_WW_Pin1_4 6 11 PF00397 0.441
DOC_WW_Pin1_4 787 792 PF00397 0.448
DOC_WW_Pin1_4 798 803 PF00397 0.436
DOC_WW_Pin1_4 829 834 PF00397 0.329
LIG_14-3-3_CanoR_1 1012 1016 PF00244 0.387
LIG_14-3-3_CanoR_1 1127 1131 PF00244 0.620
LIG_14-3-3_CanoR_1 182 190 PF00244 0.449
LIG_14-3-3_CanoR_1 217 223 PF00244 0.337
LIG_14-3-3_CanoR_1 756 760 PF00244 0.339
LIG_14-3-3_CanoR_1 774 783 PF00244 0.209
LIG_14-3-3_CanoR_1 831 840 PF00244 0.465
LIG_14-3-3_CanoR_1 86 91 PF00244 0.462
LIG_14-3-3_CanoR_1 984 989 PF00244 0.387
LIG_BIR_II_1 1 5 PF00653 0.608
LIG_BIR_III_4 40 44 PF00653 0.413
LIG_BRCT_BRCA1_1 986 990 PF00533 0.387
LIG_Clathr_ClatBox_1 845 849 PF01394 0.242
LIG_deltaCOP1_diTrp_1 34 42 PF00928 0.265
LIG_DLG_GKlike_1 984 991 PF00625 0.387
LIG_EH1_1 958 966 PF00400 0.442
LIG_FHA_1 1049 1055 PF00498 0.575
LIG_FHA_1 1059 1065 PF00498 0.655
LIG_FHA_1 138 144 PF00498 0.343
LIG_FHA_1 147 153 PF00498 0.347
LIG_FHA_1 218 224 PF00498 0.329
LIG_FHA_1 499 505 PF00498 0.394
LIG_FHA_1 531 537 PF00498 0.433
LIG_FHA_1 799 805 PF00498 0.507
LIG_FHA_1 811 817 PF00498 0.348
LIG_FHA_1 972 978 PF00498 0.419
LIG_FHA_2 1101 1107 PF00498 0.750
LIG_FHA_2 1116 1122 PF00498 0.535
LIG_FHA_2 23 29 PF00498 0.405
LIG_FHA_2 235 241 PF00498 0.477
LIG_FHA_2 320 326 PF00498 0.384
LIG_FHA_2 87 93 PF00498 0.345
LIG_FHA_2 892 898 PF00498 0.394
LIG_IBAR_NPY_1 419 421 PF08397 0.553
LIG_Integrin_isoDGR_2 643 645 PF01839 0.520
LIG_Integrin_RGD_1 14 16 PF01839 0.473
LIG_IRF3_LxIS_1 703 710 PF10401 0.382
LIG_LIR_Apic_2 1043 1049 PF02991 0.352
LIG_LIR_Apic_2 329 334 PF02991 0.391
LIG_LIR_Apic_2 345 349 PF02991 0.625
LIG_LIR_Apic_2 497 502 PF02991 0.481
LIG_LIR_Apic_2 580 586 PF02991 0.427
LIG_LIR_Apic_2 976 981 PF02991 0.444
LIG_LIR_Gen_1 220 228 PF02991 0.419
LIG_LIR_Gen_1 370 379 PF02991 0.554
LIG_LIR_Gen_1 480 489 PF02991 0.331
LIG_LIR_Gen_1 715 725 PF02991 0.423
LIG_LIR_Gen_1 746 757 PF02991 0.303
LIG_LIR_Gen_1 775 784 PF02991 0.393
LIG_LIR_Gen_1 790 798 PF02991 0.500
LIG_LIR_Gen_1 835 845 PF02991 0.419
LIG_LIR_Gen_1 849 858 PF02991 0.293
LIG_LIR_Gen_1 897 906 PF02991 0.481
LIG_LIR_Gen_1 935 944 PF02991 0.390
LIG_LIR_Gen_1 983 993 PF02991 0.481
LIG_LIR_Nem_3 1027 1033 PF02991 0.332
LIG_LIR_Nem_3 220 225 PF02991 0.421
LIG_LIR_Nem_3 313 317 PF02991 0.423
LIG_LIR_Nem_3 370 376 PF02991 0.552
LIG_LIR_Nem_3 40 45 PF02991 0.278
LIG_LIR_Nem_3 477 481 PF02991 0.363
LIG_LIR_Nem_3 715 720 PF02991 0.456
LIG_LIR_Nem_3 746 752 PF02991 0.304
LIG_LIR_Nem_3 775 779 PF02991 0.359
LIG_LIR_Nem_3 781 785 PF02991 0.339
LIG_LIR_Nem_3 790 796 PF02991 0.403
LIG_LIR_Nem_3 835 840 PF02991 0.339
LIG_LIR_Nem_3 849 855 PF02991 0.210
LIG_LIR_Nem_3 897 902 PF02991 0.438
LIG_LIR_Nem_3 911 916 PF02991 0.337
LIG_LIR_Nem_3 935 940 PF02991 0.390
LIG_LIR_Nem_3 983 988 PF02991 0.398
LIG_LYPXL_yS_3 617 620 PF13949 0.387
LIG_NRBOX 666 672 PF00104 0.337
LIG_NRBOX 803 809 PF00104 0.432
LIG_Pex14_2 222 226 PF04695 0.415
LIG_Pex14_2 495 499 PF04695 0.387
LIG_Pex14_2 636 640 PF04695 0.387
LIG_SH2_CRK 1021 1025 PF00017 0.328
LIG_SH2_CRK 373 377 PF00017 0.463
LIG_SH2_CRK 717 721 PF00017 0.424
LIG_SH2_CRK 776 780 PF00017 0.386
LIG_SH2_CRK 913 917 PF00017 0.387
LIG_SH2_CRK 993 997 PF00017 0.387
LIG_SH2_NCK_1 481 485 PF00017 0.347
LIG_SH2_NCK_1 622 626 PF00017 0.481
LIG_SH2_PTP2 118 121 PF00017 0.336
LIG_SH2_PTP2 852 855 PF00017 0.265
LIG_SH2_PTP2 899 902 PF00017 0.481
LIG_SH2_SRC 252 255 PF00017 0.431
LIG_SH2_SRC 899 902 PF00017 0.481
LIG_SH2_STAP1 776 780 PF00017 0.386
LIG_SH2_STAT3 470 473 PF00017 0.512
LIG_SH2_STAT3 508 511 PF00017 0.481
LIG_SH2_STAT3 677 680 PF00017 0.457
LIG_SH2_STAT3 868 871 PF00017 0.611
LIG_SH2_STAT3 909 912 PF00017 0.387
LIG_SH2_STAT5 1047 1050 PF00017 0.361
LIG_SH2_STAT5 118 121 PF00017 0.336
LIG_SH2_STAT5 133 136 PF00017 0.381
LIG_SH2_STAT5 180 183 PF00017 0.342
LIG_SH2_STAT5 326 329 PF00017 0.420
LIG_SH2_STAT5 508 511 PF00017 0.387
LIG_SH2_STAT5 719 722 PF00017 0.268
LIG_SH2_STAT5 837 840 PF00017 0.376
LIG_SH2_STAT5 852 855 PF00017 0.188
LIG_SH2_STAT5 868 871 PF00017 0.480
LIG_SH2_STAT5 899 902 PF00017 0.387
LIG_SH2_STAT5 909 912 PF00017 0.387
LIG_SH2_STAT5 937 940 PF00017 0.387
LIG_SH2_STAT5 985 988 PF00017 0.387
LIG_SH3_1 1056 1062 PF00018 0.652
LIG_SH3_2 513 518 PF14604 0.401
LIG_SH3_3 1056 1062 PF00018 0.564
LIG_SH3_3 331 337 PF00018 0.429
LIG_SH3_3 510 516 PF00018 0.401
LIG_SH3_3 557 563 PF00018 0.442
LIG_SH3_3 754 760 PF00018 0.334
LIG_SH3_3 897 903 PF00018 0.387
LIG_SH3_5 369 373 PF00018 0.582
LIG_SUMO_SIM_anti_2 185 191 PF11976 0.405
LIG_SUMO_SIM_anti_2 32 37 PF11976 0.264
LIG_SUMO_SIM_par_1 844 849 PF11976 0.247
LIG_SUMO_SIM_par_1 85 92 PF11976 0.336
LIG_TRAF2_1 345 348 PF00917 0.547
LIG_TRAF2_1 999 1002 PF00917 0.481
LIG_TRFH_1 264 268 PF08558 0.351
LIG_TYR_ITIM 991 996 PF00017 0.387
LIG_TYR_ITSM 909 916 PF00017 0.387
LIG_UBA3_1 273 280 PF00899 0.458
LIG_UBA3_1 438 446 PF00899 0.483
LIG_UBA3_1 521 527 PF00899 0.481
LIG_UBA3_1 670 678 PF00899 0.505
LIG_UBA3_1 971 980 PF00899 0.401
LIG_Vh1_VBS_1 656 674 PF01044 0.342
LIG_WRC_WIRS_1 1087 1092 PF05994 0.599
LIG_WRC_WIRS_1 328 333 PF05994 0.517
LIG_WRC_WIRS_1 45 50 PF05994 0.272
LIG_WRC_WIRS_1 64 69 PF05994 0.311
LIG_WRC_WIRS_1 779 784 PF05994 0.333
LIG_WW_1 625 628 PF00397 0.481
MOD_CDK_SPxK_1 191 197 PF00069 0.482
MOD_CDK_SPxK_1 6 12 PF00069 0.434
MOD_CK1_1 1026 1032 PF00069 0.332
MOD_CK1_1 185 191 PF00069 0.494
MOD_CK1_1 2 8 PF00069 0.611
MOD_CK1_1 215 221 PF00069 0.373
MOD_CK1_1 286 292 PF00069 0.459
MOD_CK1_1 49 55 PF00069 0.414
MOD_CK1_1 65 71 PF00069 0.417
MOD_CK1_1 832 838 PF00069 0.434
MOD_CK1_1 926 932 PF00069 0.481
MOD_CK2_1 1115 1121 PF00069 0.541
MOD_CK2_1 22 28 PF00069 0.412
MOD_CK2_1 342 348 PF00069 0.601
MOD_CK2_1 457 463 PF00069 0.571
MOD_CK2_1 477 483 PF00069 0.382
MOD_CK2_1 491 497 PF00069 0.344
MOD_CK2_1 833 839 PF00069 0.368
MOD_CK2_1 856 862 PF00069 0.500
MOD_CK2_1 996 1002 PF00069 0.481
MOD_GlcNHglycan 173 176 PF01048 0.328
MOD_GlcNHglycan 182 185 PF01048 0.343
MOD_GlcNHglycan 216 220 PF01048 0.455
MOD_GlcNHglycan 242 245 PF01048 0.489
MOD_GlcNHglycan 546 549 PF01048 0.220
MOD_GlcNHglycan 658 661 PF01048 0.459
MOD_GlcNHglycan 776 779 PF01048 0.394
MOD_GlcNHglycan 913 916 PF01048 0.187
MOD_GSK3_1 1 8 PF00069 0.666
MOD_GSK3_1 1058 1065 PF00069 0.555
MOD_GSK3_1 146 153 PF00069 0.477
MOD_GSK3_1 169 176 PF00069 0.300
MOD_GSK3_1 240 247 PF00069 0.343
MOD_GSK3_1 282 289 PF00069 0.438
MOD_GSK3_1 542 549 PF00069 0.438
MOD_GSK3_1 63 70 PF00069 0.399
MOD_GSK3_1 635 642 PF00069 0.404
MOD_GSK3_1 703 710 PF00069 0.442
MOD_GSK3_1 774 781 PF00069 0.386
MOD_GSK3_1 829 836 PF00069 0.331
MOD_GSK3_1 879 886 PF00069 0.395
MOD_GSK3_1 924 931 PF00069 0.387
MOD_GSK3_1 980 987 PF00069 0.481
MOD_N-GLC_1 244 249 PF02516 0.476
MOD_N-GLC_1 62 67 PF02516 0.452
MOD_N-GLC_1 786 791 PF02516 0.484
MOD_N-GLC_2 302 304 PF02516 0.457
MOD_NEK2_1 1 6 PF00069 0.573
MOD_NEK2_1 131 136 PF00069 0.402
MOD_NEK2_1 156 161 PF00069 0.344
MOD_NEK2_1 206 211 PF00069 0.382
MOD_NEK2_1 374 379 PF00069 0.480
MOD_NEK2_1 46 51 PF00069 0.311
MOD_NEK2_1 462 467 PF00069 0.551
MOD_NEK2_1 503 508 PF00069 0.427
MOD_NEK2_1 543 548 PF00069 0.398
MOD_NEK2_1 567 572 PF00069 0.392
MOD_NEK2_1 67 72 PF00069 0.331
MOD_NEK2_1 707 712 PF00069 0.504
MOD_NEK2_1 796 801 PF00069 0.466
MOD_NEK2_1 867 872 PF00069 0.556
MOD_NEK2_1 924 929 PF00069 0.387
MOD_NEK2_1 933 938 PF00069 0.387
MOD_NEK2_1 996 1001 PF00069 0.481
MOD_NEK2_2 1011 1016 PF00069 0.387
MOD_NEK2_2 778 783 PF00069 0.330
MOD_PIKK_1 2 8 PF00454 0.612
MOD_PIKK_1 244 250 PF00454 0.339
MOD_PIKK_1 422 428 PF00454 0.548
MOD_PIKK_1 49 55 PF00454 0.413
MOD_PIKK_1 737 743 PF00454 0.447
MOD_PIKK_1 867 873 PF00454 0.517
MOD_PIKK_1 908 914 PF00454 0.387
MOD_PK_1 412 418 PF00069 0.566
MOD_PKA_2 1011 1017 PF00069 0.387
MOD_PKA_2 1126 1132 PF00069 0.624
MOD_PKA_2 755 761 PF00069 0.338
MOD_PKA_2 879 885 PF00069 0.387
MOD_Plk_1 1042 1048 PF00069 0.349
MOD_Plk_1 156 162 PF00069 0.423
MOD_Plk_1 185 191 PF00069 0.405
MOD_Plk_1 206 212 PF00069 0.286
MOD_Plk_1 244 250 PF00069 0.471
MOD_Plk_1 355 361 PF00069 0.435
MOD_Plk_1 462 468 PF00069 0.545
MOD_Plk_1 491 497 PF00069 0.416
MOD_Plk_1 62 68 PF00069 0.456
MOD_Plk_1 745 751 PF00069 0.445
MOD_Plk_1 891 897 PF00069 0.401
MOD_Plk_2-3 1004 1010 PF00069 0.387
MOD_Plk_2-3 1086 1092 PF00069 0.552
MOD_Plk_2-3 477 483 PF00069 0.414
MOD_Plk_2-3 891 897 PF00069 0.401
MOD_Plk_4 1042 1048 PF00069 0.389
MOD_Plk_4 1050 1056 PF00069 0.464
MOD_Plk_4 1062 1068 PF00069 0.398
MOD_Plk_4 156 162 PF00069 0.459
MOD_Plk_4 185 191 PF00069 0.416
MOD_Plk_4 206 212 PF00069 0.286
MOD_Plk_4 218 224 PF00069 0.317
MOD_Plk_4 310 316 PF00069 0.434
MOD_Plk_4 327 333 PF00069 0.516
MOD_Plk_4 388 394 PF00069 0.508
MOD_Plk_4 41 47 PF00069 0.406
MOD_Plk_4 412 418 PF00069 0.559
MOD_Plk_4 503 509 PF00069 0.404
MOD_Plk_4 546 552 PF00069 0.452
MOD_Plk_4 778 784 PF00069 0.331
MOD_Plk_4 933 939 PF00069 0.387
MOD_ProDKin_1 1055 1061 PF00069 0.525
MOD_ProDKin_1 1066 1072 PF00069 0.517
MOD_ProDKin_1 191 197 PF00069 0.482
MOD_ProDKin_1 264 270 PF00069 0.347
MOD_ProDKin_1 283 289 PF00069 0.274
MOD_ProDKin_1 296 302 PF00069 0.282
MOD_ProDKin_1 457 463 PF00069 0.606
MOD_ProDKin_1 498 504 PF00069 0.481
MOD_ProDKin_1 6 12 PF00069 0.434
MOD_ProDKin_1 787 793 PF00069 0.445
MOD_ProDKin_1 798 804 PF00069 0.428
MOD_ProDKin_1 829 835 PF00069 0.335
MOD_SUMO_for_1 1024 1027 PF00179 0.401
MOD_SUMO_for_1 553 556 PF00179 0.481
MOD_SUMO_rev_2 1045 1054 PF00179 0.527
MOD_SUMO_rev_2 610 616 PF00179 0.447
TRG_DiLeu_BaEn_1 765 770 PF01217 0.429
TRG_DiLeu_BaEn_3 370 376 PF01217 0.594
TRG_DiLeu_BaLyEn_6 138 143 PF01217 0.356
TRG_DiLeu_BaLyEn_6 499 504 PF01217 0.481
TRG_DiLeu_BaLyEn_6 807 812 PF01217 0.270
TRG_DiLeu_BaLyEn_6 817 822 PF01217 0.319
TRG_ENDOCYTIC_2 1021 1024 PF00928 0.302
TRG_ENDOCYTIC_2 118 121 PF00928 0.337
TRG_ENDOCYTIC_2 373 376 PF00928 0.464
TRG_ENDOCYTIC_2 459 462 PF00928 0.468
TRG_ENDOCYTIC_2 481 484 PF00928 0.372
TRG_ENDOCYTIC_2 617 620 PF00928 0.387
TRG_ENDOCYTIC_2 64 67 PF00928 0.311
TRG_ENDOCYTIC_2 653 656 PF00928 0.310
TRG_ENDOCYTIC_2 717 720 PF00928 0.432
TRG_ENDOCYTIC_2 776 779 PF00928 0.297
TRG_ENDOCYTIC_2 793 796 PF00928 0.329
TRG_ENDOCYTIC_2 837 840 PF00928 0.376
TRG_ENDOCYTIC_2 852 855 PF00928 0.188
TRG_ENDOCYTIC_2 899 902 PF00928 0.438
TRG_ENDOCYTIC_2 913 916 PF00928 0.337
TRG_ENDOCYTIC_2 937 940 PF00928 0.387
TRG_ENDOCYTIC_2 985 988 PF00928 0.387
TRG_ENDOCYTIC_2 993 996 PF00928 0.387
TRG_ER_diArg_1 197 200 PF00400 0.380
TRG_ER_diArg_1 249 251 PF00400 0.307
TRG_NLS_MonoExtC_3 445 450 PF00514 0.505
TRG_NLS_MonoExtN_4 443 450 PF00514 0.468
TRG_Pf-PMV_PEXEL_1 569 573 PF00026 0.207
TRG_Pf-PMV_PEXEL_1 819 824 PF00026 0.474
TRG_Pf-PMV_PEXEL_1 893 897 PF00026 0.187
TRG_Pf-PMV_PEXEL_1 941 945 PF00026 0.187

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P8P8 Leptomonas seymouri 89% 100%
A0A1X0P284 Trypanosomatidae 60% 100%
A0A3R7M0B3 Trypanosoma rangeli 61% 100%
A4HHW9 Leishmania braziliensis 94% 100%
A4I519 Leishmania infantum 100% 100%
C9ZQH8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 100%
E9B0E9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4Q7T4 Leishmania major 98% 100%
V5BCC5 Trypanosoma cruzi 62% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS