Glyceraldehyde-3-phosphate dehydrogenase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glyceraldehyde 3-phosphate dehydrogenase, cytosolic

Species:

Leishmania donovani

UniProt:

A0A3Q8IJ37_LEIDO

TriTrypDb:

LdBPK_362480.1 , LdCL_360030500 , LDHU3_36.3310

Length:

331

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 9

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJ37

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJ37

Function

Biological processes
Term	Name	Level	Count
GO:0005975	carbohydrate metabolic process	3	8
GO:0005996	monosaccharide metabolic process	3	8
GO:0006006	glucose metabolic process	5	8
GO:0006082	organic acid metabolic process	3	8
GO:0006090	pyruvate metabolic process	7	8
GO:0006091	generation of precursor metabolites and energy	3	8
GO:0006096	glycolytic process	5	8
GO:0006139	nucleobase-containing compound metabolic process	3	8
GO:0006163	purine nucleotide metabolic process	5	8
GO:0006165	obsolete nucleoside diphosphate phosphorylation	6	8
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006753	nucleoside phosphate metabolic process	4	8
GO:0006757	obsolete ATP generation from ADP	4	8
GO:0006793	phosphorus metabolic process	3	8
GO:0006796	phosphate-containing compound metabolic process	4	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0008152	metabolic process	1	8
GO:0009056	catabolic process	2	8
GO:0009117	nucleotide metabolic process	5	8
GO:0009132	nucleoside diphosphate metabolic process	5	8
GO:0009135	purine nucleoside diphosphate metabolic process	6	8
GO:0009141	nucleoside triphosphate metabolic process	5	8
GO:0009144	purine nucleoside triphosphate metabolic process	6	8
GO:0009150	purine ribonucleotide metabolic process	6	8
GO:0009179	purine ribonucleoside diphosphate metabolic process	7	8
GO:0009185	ribonucleoside diphosphate metabolic process	6	8
GO:0009199	ribonucleoside triphosphate metabolic process	6	8
GO:0009205	purine ribonucleoside triphosphate metabolic process	7	8
GO:0009259	ribonucleotide metabolic process	5	8
GO:0009987	cellular process	1	8
GO:0016052	carbohydrate catabolic process	4	8
GO:0016310	phosphorylation	5	8
GO:0019318	hexose metabolic process	4	8
GO:0019637	organophosphate metabolic process	3	8
GO:0019693	ribose phosphate metabolic process	4	8
GO:0019752	carboxylic acid metabolic process	5	8
GO:0032787	monocarboxylic acid metabolic process	6	8
GO:0034641	cellular nitrogen compound metabolic process	3	8
GO:0043436	oxoacid metabolic process	4	8
GO:0044237	cellular metabolic process	2	8
GO:0044238	primary metabolic process	2	8
GO:0044281	small molecule metabolic process	2	8
GO:0046031	ADP metabolic process	7	8
GO:0046034	ATP metabolic process	7	8
GO:0046483	heterocycle metabolic process	3	8
GO:0046939	obsolete nucleotide phosphorylation	6	8
GO:0055086	nucleobase-containing small molecule metabolic process	3	8
GO:0071704	organic substance metabolic process	2	8
GO:0072521	purine-containing compound metabolic process	4	8
GO:1901135	carbohydrate derivative metabolic process	3	8
GO:1901360	organic cyclic compound metabolic process	3	8
GO:1901564	organonitrogen compound metabolic process	3	8
GO:1901575	organic substance catabolic process	3	8

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003824	catalytic activity	1	8
GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	6	8
GO:0005488	binding	1	8
GO:0016491	oxidoreductase activity	2	8
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4	8
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	8
GO:0036094	small molecule binding	2	8
GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	5	8
GO:0050661	NADP binding	4	8
GO:0051287	NAD binding	4	8
GO:0097159	organic cyclic compound binding	2	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	33	37	PF00656	0.522
CLV_PCSK_KEX2_1	114	116	PF00082	0.602
CLV_PCSK_PC1ET2_1	114	116	PF00082	0.602
CLV_PCSK_SKI1_1	14	18	PF00082	0.326
CLV_PCSK_SKI1_1	248	252	PF00082	0.329
CLV_PCSK_SKI1_1	268	272	PF00082	0.353
DEG_SCF_FBW7_1	232	238	PF00400	0.540
DOC_CKS1_1	232	237	PF01111	0.540
DOC_CYCLIN_yCln2_LP_2	246	252	PF00134	0.557
DOC_MAPK_MEF2A_6	231	239	PF00069	0.537
DOC_MAPK_MEF2A_6	83	91	PF00069	0.576
DOC_PP1_RVXF_1	12	18	PF00149	0.580
DOC_PP1_RVXF_1	304	311	PF00149	0.540
DOC_PP2B_PxIxI_1	23	29	PF00149	0.612
DOC_PP4_FxxP_1	230	233	PF00568	0.540
DOC_USP7_MATH_1	235	239	PF00917	0.540
DOC_USP7_MATH_1	287	291	PF00917	0.522
DOC_USP7_UBL2_3	212	216	PF12436	0.557
DOC_WW_Pin1_4	123	128	PF00397	0.501
DOC_WW_Pin1_4	231	236	PF00397	0.528
LIG_14-3-3_CanoR_1	197	205	PF00244	0.630
LIG_14-3-3_CanoR_1	72	79	PF00244	0.536
LIG_BRCT_BRCA1_1	279	283	PF00533	0.612
LIG_EH1_1	318	326	PF00400	0.473
LIG_FHA_1	149	155	PF00498	0.431
LIG_FHA_1	232	238	PF00498	0.528
LIG_FHA_1	241	247	PF00498	0.521
LIG_FHA_1	54	60	PF00498	0.564
LIG_FHA_1	68	74	PF00498	0.590
LIG_FHA_2	20	26	PF00498	0.630
LIG_FHA_2	249	255	PF00498	0.612
LIG_FHA_2	272	278	PF00498	0.557
LIG_LIR_Gen_1	302	311	PF02991	0.540
LIG_LIR_LC3C_4	61	66	PF02991	0.612
LIG_LIR_Nem_3	251	255	PF02991	0.540
LIG_LIR_Nem_3	280	286	PF02991	0.612
LIG_LIR_Nem_3	302	307	PF02991	0.540
LIG_LIR_Nem_3	36	42	PF02991	0.540
LIG_LYPXL_S_1	217	221	PF13949	0.412
LIG_LYPXL_yS_3	218	221	PF13949	0.612
LIG_PTB_Apo_2	159	166	PF02174	0.580
LIG_PTB_Phospho_1	159	165	PF10480	0.630
LIG_SH2_GRB2like	311	314	PF00017	0.411
LIG_SH2_STAP1	317	321	PF00017	0.413
LIG_SH2_STAP1	42	46	PF00017	0.630
LIG_SH2_STAT3	138	141	PF00017	0.547
LIG_SH2_STAT5	273	276	PF00017	0.557
LIG_SH2_STAT5	327	330	PF00017	0.471
LIG_SH3_3	182	188	PF00018	0.540
LIG_SH3_3	229	235	PF00018	0.529
LIG_SUMO_SIM_anti_2	25	30	PF11976	0.540
LIG_SUMO_SIM_par_1	238	243	PF11976	0.534
MOD_CK1_1	145	151	PF00069	0.439
MOD_CK2_1	271	277	PF00069	0.572
MOD_DYRK1A_RPxSP_1	231	235	PF00069	0.540
MOD_GlcNHglycan	328	331	PF01048	0.598
MOD_GSK3_1	171	178	PF00069	0.557
MOD_GSK3_1	231	238	PF00069	0.540
MOD_GSK3_1	67	74	PF00069	0.607
MOD_N-GLC_1	133	138	PF02516	0.474
MOD_N-GLC_1	145	150	PF02516	0.441
MOD_N-GLC_1	235	240	PF02516	0.336
MOD_N-GLC_1	312	317	PF02516	0.408
MOD_N-GLC_1	53	58	PF02516	0.375
MOD_NEK2_1	171	176	PF00069	0.540
MOD_NEK2_1	326	331	PF00069	0.558
MOD_NEK2_1	40	45	PF00069	0.640
MOD_NEK2_1	53	58	PF00069	0.560
MOD_NEK2_2	287	292	PF00069	0.540
MOD_PIKK_1	178	184	PF00454	0.540
MOD_PIKK_1	197	203	PF00454	0.540
MOD_PKA_2	71	77	PF00069	0.540
MOD_Plk_1	133	139	PF00069	0.482
MOD_Plk_1	235	241	PF00069	0.540
MOD_Plk_2-3	186	192	PF00069	0.612
MOD_Plk_4	235	241	PF00069	0.532
MOD_Plk_4	287	293	PF00069	0.540
MOD_Plk_4	306	312	PF00069	0.580
MOD_ProDKin_1	123	129	PF00069	0.496
MOD_ProDKin_1	231	237	PF00069	0.528
MOD_SUMO_rev_2	264	270	PF00179	0.536
MOD_SUMO_rev_2	290	296	PF00179	0.551
TRG_ENDOCYTIC_2	218	221	PF00928	0.612
TRG_ENDOCYTIC_2	252	255	PF00928	0.534

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0H3MAB5	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	51%	98%
A0A0N1PDI1	Leptomonas seymouri	88%	100%
A0A0S4IV72	Bodo saltans	54%	92%
A0A0S4JCP6	Bodo saltans	40%	98%
A0A1X0P1G4	Trypanosomatidae	53%	92%
A0A1X0P6C0	Trypanosomatidae	32%	95%
A0A1X0P8Z3	Trypanosomatidae	83%	100%
A0A3Q8IQ62	Leishmania donovani	27%	95%
A0A3R7KES2	Trypanosoma rangeli	52%	92%
A0A3R7LC67	Trypanosoma rangeli	31%	97%
A0A3R7NEP8	Trypanosoma rangeli	86%	100%
A0A3S7X3R3	Leishmania donovani	53%	92%
A0KGD2	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	38%	99%
A0L0K7	Shewanella sp. (strain ANA-3)	37%	98%
A0QWW2	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	51%	97%
A1AFB1	Escherichia coli O1:K1 / APEC	39%	98%
A1JPR1	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	36%	98%
A1RN69	Shewanella sp. (strain W3-18-1)	37%	98%
A1S9A4	Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)	38%	98%
A1SVN9	Psychromonas ingrahamii (strain 37)	35%	89%
A2YQT7	Oryza sativa subsp. indica	60%	98%
A3FKF7	Mustela putorius furo	67%	99%
A3QAX7	Shewanella loihica (strain ATCC BAA-1088 / PV-4)	36%	98%
A4HIN0	Leishmania braziliensis	52%	100%
A4HND9	Leishmania braziliensis	25%	100%
A4I5X6	Leishmania infantum	53%	100%
A4IC12	Leishmania infantum	26%	100%
A4IDK9	Leishmania infantum	99%	100%
A4SRF2	Aeromonas salmonicida (strain A449)	38%	99%
A4WE72	Enterobacter sp. (strain 638)	39%	98%
A4Y3R9	Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)	37%	98%
A5F9G1	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	36%	97%
A6TDT2	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	38%	97%
A7MJQ2	Cronobacter sakazakii (strain ATCC BAA-894)	37%	98%
A7MTQ2	Vibrio campbellii (strain ATCC BAA-1116)	35%	96%
A7ZR35	Escherichia coli O139:H28 (strain E24377A / ETEC)	40%	98%
A8A467	Escherichia coli O9:H4 (strain HS)	40%	98%
A8APE1	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	39%	98%
A8H0M9	Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)	36%	98%
A9MRF0	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	39%	97%
A9N3Q6	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	39%	95%
B0B879	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)	59%	99%
B0TUC0	Shewanella halifaxensis (strain HAW-EB4)	36%	98%
B1IT76	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	40%	98%
B1LDD2	Escherichia coli (strain SMS-3-5 / SECEC)	40%	98%
B1XEL0	Escherichia coli (strain K12 / DH10B)	40%	98%
B2U0U3	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	40%	98%
B2VF24	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	36%	95%
B4EUH7	Proteus mirabilis (strain HI4320)	37%	98%
B4RWC5	Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)	36%	99%
B4T5H2	Salmonella newport (strain SL254)	39%	95%
B4THF4	Salmonella heidelberg (strain SL476)	39%	95%
B4TV39	Salmonella schwarzengrund (strain CVM19633)	39%	95%
B5BFN5	Salmonella paratyphi A (strain AKU_12601)	39%	95%
B5F5J5	Salmonella agona (strain SL483)	39%	95%
B5F9T4	Aliivibrio fischeri (strain MJ11)	36%	98%
B5FUI3	Salmonella dublin (strain CT_02021853)	39%	95%
B5QXJ7	Salmonella enteritidis PT4 (strain P125109)	39%	95%
B5RE31	Salmonella gallinarum (strain 287/91 / NCTC 13346)	39%	95%
B5XUB7	Klebsiella pneumoniae (strain 342)	38%	97%
B5YQB9	Escherichia coli O157:H7 (strain EC4115 / EHEC)	40%	98%
B6EMW1	Aliivibrio salmonicida (strain LFI1238)	37%	98%
B6I761	Escherichia coli (strain SE11)	40%	98%
B7LFI3	Escherichia coli (strain 55989 / EAEC)	40%	98%
B7LPD5	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	40%	98%
B7LQ20	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	81%	100%
B7LYU4	Escherichia coli O8 (strain IAI1)	40%	98%
B7MMA9	Escherichia coli O45:K1 (strain S88 / ExPEC)	39%	98%
B7MZM0	Escherichia coli O81 (strain ED1a)	40%	98%
B7N7H3	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	40%	98%
B7NHY6	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	39%	98%
B7UHW9	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	40%	98%
B8CU41	Shewanella piezotolerans (strain WP3 / JCM 13877)	37%	98%
B8E5U5	Shewanella baltica (strain OS223)	37%	98%
C0PY46	Salmonella paratyphi C (strain RKS4594)	39%	95%
C4L9J3	Tolumonas auensis (strain DSM 9187 / TA4)	35%	98%
C5A0J7	Escherichia coli (strain K12 / MC4100 / BW2952)	40%	98%
C5BAU7	Edwardsiella ictaluri (strain 93-146)	34%	97%
C6DFH8	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	36%	98%
C9ZRA3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	82%
C9ZYJ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	93%
D0A3A8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	83%	100%
E3VWI2	Streptomyces arenae	48%	99%
E9AFV0	Leishmania major	26%	100%
E9AT12	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9B170	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9B703	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
I2BA89	Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74)	82%	100%
O01360	Onchocerca volvulus	63%	98%
O09452	Guillardia theta	59%	86%
O13507	Phaffia rhodozyma	66%	98%
O14556	Homo sapiens	63%	81%
O16027	Globodera rostochiensis	65%	100%
O32755	Lactobacillus delbrueckii subsp. bulgaricus	43%	98%
O34425	Bacillus subtilis (strain 168)	48%	97%
O42259	Oncorhynchus mykiss	62%	99%
O43026	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	69%	99%
O44104	Drosophila pseudoobscura pseudoobscura	65%	100%
O44105	Drosophila subobscura	66%	100%
O52631	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	48%	99%
O57479	Columba livia	66%	99%
O57672	Meleagris gallopavo	71%	100%
O59841	Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1)	67%	99%
O67161	Aquifex aeolicus (strain VF5)	49%	97%
O83816	Treponema pallidum (strain Nichols)	47%	95%
O96423	Crithidia fasciculata	53%	92%
O96425	Leptomonas seymouri	52%	92%
P00355	Sus scrofa	66%	99%
P00356	Gallus gallus	66%	99%
P00357	Homarus americanus	64%	99%
P00358	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	64%	100%
P00359	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	65%	100%
P00360	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	65%	100%
P00361	Thermus aquaticus	50%	100%
P00362	Geobacillus stearothermophilus	58%	99%
P04406	Homo sapiens	66%	99%
P04796	Sinapis alba	62%	98%
P04797	Rattus norvegicus	67%	99%
P04970	Caenorhabditis elegans	62%	97%
P07486	Drosophila melanogaster	65%	100%
P07487	Drosophila melanogaster	65%	100%
P08439	Zygosaccharomyces rouxii	65%	99%
P08477	Hordeum vulgare	62%	100%
P08735	Zea mays	62%	98%
P09043	Nicotiana tabacum	48%	84%
P09044	Nicotiana tabacum	48%	76%
P09094	Nicotiana tabacum	62%	100%
P09124	Bacillus subtilis (strain 168)	55%	99%
P09315	Zea mays	50%	82%
P09316	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	48%	98%
P09317	Ustilago maydis (strain 521 / FGSC 9021)	65%	98%
P09672	Sinapis alba	52%	100%
P0A036	Staphylococcus aureus (strain Mu50 / ATCC 700699)	47%	99%
P0A037	Staphylococcus aureus (strain MW2)	47%	99%
P0A038	Staphylococcus aureus	47%	99%
P0A1P0	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	81%	100%
P0A1P1	Salmonella typhi	81%	100%
P0A9B2	Escherichia coli (strain K12)	82%	100%
P0A9B3	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	82%	100%
P0A9B4	Escherichia coli O157:H7	82%	100%
P0A9B5	Shigella flexneri	82%	100%
P0A9B6	Escherichia coli (strain K12)	40%	98%
P0A9B7	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	40%	98%
P0A9B8	Escherichia coli O157:H7	40%	98%
P0A9B9	Shigella flexneri	40%	98%
P0C0G6	Streptococcus pyogenes	49%	99%
P0C0G7	Streptococcus pyogenes serotype M1	50%	99%
P0C6C2	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	36%	97%
P0C8Z1	Escherichia fergusonii	81%	100%
P0CE13	Chlamydia trachomatis (strain D/UW-3/Cx)	58%	99%
P0CN74	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	66%	98%
P0CN75	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	66%	98%
P0DB18	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	49%	99%
P0DB19	Streptococcus pyogenes serotype M3 (strain SSI-1)	49%	99%
P0DJO7	Shimwellia blattae	82%	100%
P10096	Bos taurus	67%	99%
P10097	Trypanosoma brucei brucei	82%	100%
P12858	Pisum sativum	48%	82%
P12859	Pisum sativum	48%	73%
P12860	Spinacia oleracea	48%	73%
P15115	Weizmannia coagulans	52%	99%
P16858	Mus musculus	67%	99%
P17244	Cricetulus griseus	67%	99%
P17329	Caenorhabditis elegans	63%	97%
P17330	Caenorhabditis elegans	63%	97%
P17331	Caenorhabditis elegans	62%	97%
P17721	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	50%	99%
P17729	Trichoderma koningii	60%	99%
P17730	Trichoderma koningii	66%	98%
P17819	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	63%	100%
P17878	Mesembryanthemum crystallinum	63%	98%
P19089	Cryphonectria parasitica	66%	98%
P19866	Spinacia oleracea	48%	83%
P20287	Schistosoma mansoni	64%	98%
P20445	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	65%	99%
P22512	Trypanosoma brucei brucei	54%	92%
P22513	Trypanosoma cruzi	52%	92%
P23722	Priestia megaterium (strain DSM 319 / IMG 1521)	55%	99%
P24163	Klebsiella aerogenes	81%	100%
P24164	Klebsiella pneumoniae	81%	100%
P24166	Serratia marcescens	81%	100%
P24748	Citrobacter freundii	81%	100%
P24750	Atlantibacter hermannii	82%	100%
P24751	Pseudescherichia vulneris	81%	100%
P24753	Serratia odorifera	82%	100%
P25856	Arabidopsis thaliana	49%	84%
P25857	Arabidopsis thaliana	48%	74%
P25858	Arabidopsis thaliana	62%	98%
P25861	Antirrhinum majus	62%	98%
P26517	Hordeum vulgare	62%	98%
P26518	Magnolia liliiflora	64%	97%
P26519	Petroselinum crispum	62%	99%
P26520	Petunia hybrida	62%	98%
P26521	Ranunculus acris	65%	98%
P26988	Phytophthora infestans	65%	100%
P27726	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	45%	99%
P28844	Cochliobolus lunatus	66%	98%
P29272	Cereibacter sphaeroides	48%	99%
P29497	Cochliobolus heterostrophus	66%	98%
P30724	Gracilaria gracilis	45%	80%
P32635	Agaricus bisporus	58%	98%
P32636	Agaricus bisporus	64%	98%
P32637	Podospora anserina	70%	98%
P32638	Schizophyllum commune	63%	98%
P32809	Caenorhabditis briggsae	62%	97%
P32810	Caenorhabditis briggsae	62%	97%
P34783	Atriplex nummularia	63%	92%
P34916	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	62%	97%
P34917	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	50%	98%
P34918	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	39%	98%
P34919	Chondrus crispus	46%	80%
P34920	Chondrus crispus	64%	99%
P34921	Dianthus caryophyllus	62%	98%
P34922	Pisum sativum	62%	98%
P34923	Physcomitrium patens	64%	97%
P34924	Pinus sylvestris	66%	97%
P35143	Colletotrichum gloeosporioides	64%	98%
P44304	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	80%	98%
P46406	Oryctolagus cuniculus	66%	99%
P46713	Mycobacterium leprae (strain TN)	50%	98%
P46795	Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)	52%	99%
P46796	Borrelia hermsii	52%	100%
P47543	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	46%	98%
P48812	Brugia malayi	63%	98%
P49433	Synechocystis sp. (strain PCC 6803 / Kazusa)	62%	98%
P49644	Chlamydomonas reinhardtii	63%	97%
P50321	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	50%	99%
P50322	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	50%	99%
P50362	Chlamydomonas reinhardtii	48%	89%
P51009	Xanthobacter flavus	48%	99%
P51469	Xenopus laevis	66%	99%
P51640	Mesocricetus auratus	66%	100%
P52694	Ralstonia solanacearum (strain GMI1000)	70%	100%
P52987	Lactococcus lactis subsp. lactis (strain IL1403)	46%	98%
P53429	Giardia intestinalis	58%	98%
P53430	Monascus purpureus	66%	98%
P54117	Colletotrichum lindemuthianum	65%	98%
P54118	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	66%	98%
P54226	Streptomyces arenae	48%	99%
P54270	Gracilaria gracilis	64%	99%
P55070	Lactarius deterrimus	63%	100%
P55071	Amanita muscaria	61%	100%
P55971	Helicobacter pylori (strain ATCC 700392 / 26695)	39%	100%
P56649	Panulirus versicolor	64%	99%
P57384	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	69%	100%
P58072	Escherichia coli O157:H7	45%	99%
P58554	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	50%	98%
P58559	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	39%	98%
P64179	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	51%	98%
P64180	Staphylococcus aureus (strain Mu50 / ATCC 700699)	44%	97%
P64181	Staphylococcus aureus (strain MW2)	44%	97%
P68777	Streptococcus pyogenes serotype M18 (strain MGAS8232)	50%	99%
P75358	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	47%	98%
P78958	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	69%	99%
P80505	Synechocystis sp. (strain PCC 6803 / Kazusa)	49%	98%
P80506	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	62%	97%
P80534	Jaculus orientalis	60%	91%
P84998	Kluyveromyces marxianus	63%	100%
P84999	Kluyveromyces marxianus	64%	100%
P87197	Hypocrea atroviridis	65%	98%
P94915	Mycobacterium avium	52%	98%
P99067	Staphylococcus aureus (strain N315)	44%	97%
P99136	Staphylococcus aureus (strain N315)	47%	99%
P9WN82	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	51%	98%
P9WN83	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	51%	98%
Q00301	Boletus edulis	64%	100%
Q00584	Claviceps purpurea (strain 20.1)	65%	98%
Q00640	Blumeria hordei	63%	98%
Q01077	Kluyveromyces marxianus	64%	100%
Q01558	Leishmania mexicana	95%	100%
Q01597	Drosophila hydei	65%	100%
Q01651	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	49%	99%
Q01982	Phanerodontia chrysosporium	62%	98%
Q02PG5	Pseudomonas aeruginosa (strain UCBPP-PA14)	40%	72%
Q05025	Coturnix japonica	67%	99%
Q07234	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	70%	100%
Q087Q7	Shewanella frigidimarina (strain NCIMB 400)	37%	98%
Q09054	Zea mays	61%	98%
Q0HM63	Shewanella sp. (strain MR-4)	37%	98%
Q0HRM3	Shewanella sp. (strain MR-7)	37%	98%
Q0J8A4	Oryza sativa subsp. japonica	60%	98%
Q0T0X3	Shigella flexneri serotype 5b (strain 8401)	40%	98%
Q0TDS9	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	40%	98%
Q12552	Aspergillus niger	65%	99%
Q12QA4	Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)	37%	97%
Q15QK3	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	37%	97%
Q1CB62	Yersinia pestis bv. Antiqua (strain Antiqua)	36%	98%
Q1CEY2	Yersinia pestis bv. Antiqua (strain Nepal516)	36%	98%
Q1DTF9	Coccidioides immitis (strain RS)	64%	98%
Q1R7A6	Escherichia coli (strain UTI89 / UPEC)	40%	98%
Q27652	Echinococcus multilocularis	58%	99%
Q27890	Leishmania mexicana	53%	92%
Q28259	Canis lupus familiaris	67%	99%
Q28554	Ovis aries	65%	100%
Q2KJE5	Bos taurus	63%	84%
Q2U0J7	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	60%	99%
Q31WI6	Shigella boydii serotype 4 (strain Sb227)	40%	98%
Q32BY7	Shigella dysenteriae serotype 1 (strain Sd197)	40%	98%
Q39769	Ginkgo biloba	65%	97%
Q3ILL8	Pseudoalteromonas translucida (strain TAC 125)	38%	97%
Q3YXU5	Shigella sonnei (strain Ss046)	40%	98%
Q41595	Taxus baccata	63%	97%
Q42671	Craterostigma plantagineum	61%	98%
Q43247	Zea mays	62%	98%
Q47XD5	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	36%	98%
Q48335	Haloarcula vallismortis	47%	99%
Q4KYY3	Spermophilus citellus	66%	99%
Q4MQ58	Bacillus cereus	53%	99%
Q4Q6Z4	Leishmania major	54%	100%
Q4Q6Z5	Leishmania major	54%	100%
Q4R3T1	Macaca fascicularis	63%	81%
Q4U3L0	Glossina morsitans morsitans	65%	99%
Q57K44	Salmonella choleraesuis (strain SC-B67)	39%	95%
Q59199	Bacteroides fragilis (strain YCH46)	72%	99%
Q59309	Clostridium pasteurianum	50%	99%
Q59800	Kitasatospora aureofaciens	45%	100%
Q59906	Streptococcus dysgalactiae subsp. equisimilis	48%	99%
Q5E7R0	Aliivibrio fischeri (strain ATCC 700601 / ES114)	36%	98%
Q5E924	Arabidopsis thaliana	67%	79%
Q5HF86	Staphylococcus aureus (strain COL)	44%	97%
Q5HHP5	Staphylococcus aureus (strain COL)	47%	99%
Q5HNL7	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	45%	97%
Q5HQV4	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	46%	99%
Q5MJ86	Danio rerio	63%	99%
Q5PJI5	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	39%	95%
Q5QVL6	Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)	36%	97%
Q5R2J2	Pelodiscus sinensis	68%	99%
Q5RAB4	Pongo abelii	65%	99%
Q5XDW3	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	50%	99%
Q5XJ10	Danio rerio	67%	99%
Q64467	Mus musculus	65%	75%
Q666Q0	Yersinia pseudotuberculosis serotype I (strain IP32953)	36%	98%
Q6BMK0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	65%	99%
Q6CCU7	Yarrowia lipolytica (strain CLIB 122 / E 150)	65%	98%
Q6CX23	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	65%	100%
Q6D086	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	36%	98%
Q6FPW3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	63%	100%
Q6FSM4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	64%	100%
Q6G8N9	Staphylococcus aureus (strain MSSA476)	44%	97%
Q6GB58	Staphylococcus aureus (strain MSSA476)	47%	99%
Q6GG19	Staphylococcus aureus (strain MRSA252)	44%	97%
Q6GIL8	Staphylococcus aureus (strain MRSA252)	47%	99%
Q6K5G8	Oryza sativa subsp. japonica	63%	98%
Q6LMN0	Photobacterium profundum (strain SS9)	36%	92%
Q757I2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	66%	100%
Q7CGS4	Yersinia pestis	36%	98%
Q7CPU5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	39%	95%
Q7FAH2	Oryza sativa subsp. japonica	63%	98%
Q7MHL0	Vibrio vulnificus (strain YJ016)	36%	96%
Q7N7Z6	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	36%	98%
Q829W3	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	48%	99%
Q82IZ2	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	49%	99%
Q87LL0	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	35%	96%
Q89AK1	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	69%	99%
Q8CNY0	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	45%	97%
Q8CPY5	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	46%	99%
Q8DCA1	Vibrio vulnificus (strain CMCP6)	36%	96%
Q8EIB2	Shewanella oneidensis (strain MR-1)	38%	98%
Q8J1H3	Coccidioides posadasii (strain C735)	63%	98%
Q8NK47	Rhizomucor miehei	68%	99%
Q8TFJ2	Omphalotus olearius	61%	98%
Q8VXQ8	COEVA	65%	100%
Q8VXQ9	COEVA	50%	100%
Q8WZN0	Sordaria macrospora	64%	98%
Q8X1X3	Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01)	66%	98%
Q8XGA4	Salmonella typhi	39%	95%
Q92211	Candida albicans (strain WO-1)	65%	99%
Q92243	Lyophyllum shimeji	62%	98%
Q92263	Komagataella pastoris	64%	99%
Q94469	Dictyostelium discoideum	63%	99%
Q96UF1	Mucor circinelloides f. lusitanicus	64%	98%
Q96UF2	Mucor circinelloides f. lusitanicus	68%	98%
Q96US8	Sclerotinia sclerotiorum	66%	98%
Q9C136	Mucor circinelloides f. lusitanicus	64%	98%
Q9ESV6	Rattus norvegicus	65%	77%
Q9FX54	Arabidopsis thaliana	63%	98%
Q9HFX1	Ajellomyces capsulatus	64%	98%
Q9HGY7	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	65%	98%
Q9LPW0	Arabidopsis thaliana	50%	83%
Q9N2D5	Felis catus	66%	99%
Q9N655	Mastigamoeba balamuthi	61%	98%
Q9P8C0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	66%	98%
Q9PJN6	Chlamydia muridarum (strain MoPn / Nigg)	58%	99%
Q9SAJ6	Arabidopsis thaliana	68%	78%
Q9UR38	Lentinula edodes	62%	98%
Q9UVC0	Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)	63%	99%
Q9UW96	Pleurotus sajor-caju	61%	99%
Q9Y796	Cutaneotrichosporon curvatum	66%	98%
Q9Z518	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	50%	99%
Q9Z7T0	Chlamydia pneumoniae	60%	99%
Q9ZKT0	Helicobacter pylori (strain J99 / ATCC 700824)	40%	100%
V5B797	Trypanosoma cruzi	51%	91%
V5BG34	Trypanosoma cruzi	33%	95%