Ribosomal protein L15

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L15, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IIZ6_LEIDO

TriTrypDb:

LdBPK_303710.1 , LdCL_300042500 , LdCL_350024100 , LDHU3_30.4940

Length:

204

Annotations

Annotations by Jardim et al.

Ribosomal Protein, Ribosomal L15 rpl15 PE=2 SV=1 - [Q9N9V8_LEIIN]

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 32

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 32

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	13
GO:0032991	protein-containing complex	1	15
GO:0043226	organelle	2	13
GO:0043228	non-membrane-bounded organelle	3	13
GO:0043229	intracellular organelle	3	13
GO:0043232	intracellular non-membrane-bounded organelle	4	13
GO:0110165	cellular anatomical entity	1	13
GO:1990904	ribonucleoprotein complex	2	15
GO:0015934	large ribosomal subunit	4	2
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0044391	ribosomal subunit	3	2

Expansion

Sequence features

A0A3Q8IIZ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IIZ6

PDB structure(s): 6az3_M

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	15
GO:0006518	peptide metabolic process	4	15
GO:0006807	nitrogen compound metabolic process	2	15
GO:0008152	metabolic process	1	15
GO:0009058	biosynthetic process	2	15
GO:0009059	macromolecule biosynthetic process	4	15
GO:0009987	cellular process	1	15
GO:0019538	protein metabolic process	3	15
GO:0034641	cellular nitrogen compound metabolic process	3	15
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	15
GO:0043043	peptide biosynthetic process	5	15
GO:0043170	macromolecule metabolic process	3	15
GO:0043603	amide metabolic process	3	15
GO:0043604	amide biosynthetic process	4	15
GO:0044237	cellular metabolic process	2	15
GO:0044238	primary metabolic process	2	15
GO:0044249	cellular biosynthetic process	3	15
GO:0044260	obsolete cellular macromolecule metabolic process	3	15
GO:0044271	cellular nitrogen compound biosynthetic process	4	15
GO:0071704	organic substance metabolic process	2	15
GO:1901564	organonitrogen compound metabolic process	3	15
GO:1901566	organonitrogen compound biosynthetic process	4	15
GO:1901576	organic substance biosynthetic process	3	15
GO:0002181	cytoplasmic translation	5	2

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	15
GO:0005198	structural molecule activity	1	15
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	106	112	PF00089	0.522
CLV_NRD_NRD_1	143	145	PF00675	0.417
CLV_NRD_NRD_1	168	170	PF00675	0.391
CLV_NRD_NRD_1	193	195	PF00675	0.519
CLV_NRD_NRD_1	201	203	PF00675	0.538
CLV_NRD_NRD_1	40	42	PF00675	0.401
CLV_NRD_NRD_1	67	69	PF00675	0.401
CLV_NRD_NRD_1	70	72	PF00675	0.401
CLV_PCSK_FUR_1	38	42	PF00082	0.417
CLV_PCSK_FUR_1	65	69	PF00082	0.401
CLV_PCSK_KEX2_1	108	110	PF00082	0.522
CLV_PCSK_KEX2_1	143	145	PF00082	0.417
CLV_PCSK_KEX2_1	193	195	PF00082	0.519
CLV_PCSK_KEX2_1	40	42	PF00082	0.401
CLV_PCSK_KEX2_1	67	69	PF00082	0.401
CLV_PCSK_KEX2_1	72	74	PF00082	0.401
CLV_PCSK_PC1ET2_1	108	110	PF00082	0.522
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.401
CLV_PCSK_PC7_1	189	195	PF00082	0.502
CLV_PCSK_PC7_1	63	69	PF00082	0.401
CLV_PCSK_SKI1_1	162	166	PF00082	0.401
CLV_PCSK_SKI1_1	197	201	PF00082	0.553
CLV_PCSK_SKI1_1	77	81	PF00082	0.401
DOC_MAPK_gen_1	105	115	PF00069	0.401
DOC_MAPK_gen_1	12	21	PF00069	0.401
DOC_MAPK_gen_1	193	201	PF00069	0.530
DOC_MIT_MIM_1	103	114	PF04212	0.522
DOC_PP1_RVXF_1	145	151	PF00149	0.401
DOC_PP1_RVXF_1	195	201	PF00149	0.637
DOC_USP7_MATH_1	84	88	PF00917	0.436
LIG_14-3-3_CanoR_1	114	120	PF00244	0.401
LIG_14-3-3_CanoR_1	24	29	PF00244	0.440
LIG_14-3-3_CanoR_1	31	37	PF00244	0.442
LIG_BRCT_BRCA1_1	26	30	PF00533	0.436
LIG_FHA_1	84	90	PF00498	0.401
LIG_FHA_2	41	47	PF00498	0.401
LIG_LIR_Apic_2	80	84	PF02991	0.401
LIG_LIR_Gen_1	118	127	PF02991	0.522
LIG_LIR_Nem_3	124	130	PF02991	0.401
LIG_NRP_CendR_1	202	204	PF00754	0.580
LIG_SH2_CRK	81	85	PF00017	0.401
LIG_SH2_GRB2like	6	9	PF00017	0.401
LIG_SH2_NCK_1	130	134	PF00017	0.401
LIG_SH2_STAP1	130	134	PF00017	0.401
LIG_SH2_STAT5	6	9	PF00017	0.417
LIG_SH3_2	42	47	PF14604	0.401
LIG_SH3_3	39	45	PF00018	0.401
LIG_SUMO_SIM_par_1	131	136	PF11976	0.401
MOD_CK2_1	40	46	PF00069	0.401
MOD_Cter_Amidation	106	109	PF01082	0.428
MOD_Cter_Amidation	167	170	PF01082	0.401
MOD_Cter_Amidation	69	72	PF01082	0.401
MOD_GlcNHglycan	165	168	PF01048	0.390
MOD_GlcNHglycan	86	89	PF01048	0.422
MOD_NEK2_1	123	128	PF00069	0.491
MOD_NEK2_1	138	143	PF00069	0.336
MOD_PKA_1	12	18	PF00069	0.401
MOD_PKA_1	40	46	PF00069	0.391
MOD_PKA_2	184	190	PF00069	0.391
MOD_PKA_2	40	46	PF00069	0.401
MOD_PKB_1	38	46	PF00069	0.417
MOD_Plk_1	123	129	PF00069	0.402
MOD_Plk_4	115	121	PF00069	0.401
MOD_Plk_4	32	38	PF00069	0.401
TRG_ENDOCYTIC_2	130	133	PF00928	0.487
TRG_ER_diArg_1	142	144	PF00400	0.417
TRG_ER_diArg_1	192	194	PF00400	0.509
TRG_ER_diArg_1	201	204	PF00400	0.555
TRG_ER_diArg_1	37	40	PF00400	0.403
TRG_ER_diArg_1	62	65	PF00400	0.401
TRG_ER_diArg_1	66	68	PF00400	0.401
TRG_ER_diArg_1	71	74	PF00400	0.401
TRG_NLS_MonoExtC_3	11	17	PF00514	0.401
TRG_NLS_MonoExtN_4	68	75	PF00514	0.401

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2L2	Leptomonas seymouri	99%	100%
A0A0S4JHQ9	Bodo saltans	92%	100%
A0A1X0P6Q8	Trypanosomatidae	92%	100%
A0A3R7M146	Trypanosoma rangeli	91%	100%
A2ST55	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	41%	100%
A3CW58	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	42%	100%
A3DMU2	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	43%	93%
A4FZN9	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	46%	100%
A4HIV1	Leishmania braziliensis	99%	100%
A4HML1	Leishmania braziliensis	99%	100%
A4YCU5	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	43%	94%
A6UX54	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	44%	100%
A6VIT8	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	46%	100%
A7I9D0	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	39%	100%
A9A7T0	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	46%	100%
B0R2U1	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	41%	100%
B6YSU2	Thermococcus onnurineus (strain NA1)	49%	100%
B8D6C6	Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)	45%	93%
B9LSV1	Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)	43%	100%
C3MQ39	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	42%	94%
C3MVF7	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	42%	94%
C3N5Q6	Sulfolobus islandicus (strain M.16.27)	42%	94%
C3NEC2	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	42%	94%
C3NHD0	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	42%	94%
C4KHD5	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	42%	94%
C5A1N3	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	49%	100%
C9ZRH6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	89%	100%
C9ZZL5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	88%	92%
E2QXF3	Canis lupus familiaris	59%	100%
E9AF12	Leishmania major	100%	100%
E9B1D9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
E9B668	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
O13418	Aspergillus niger	56%	100%
O17445	Drosophila melanogaster	57%	100%
O23515	Arabidopsis thaliana	63%	100%
O26786	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	40%	100%
O27965	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	44%	100%
O58706	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	49%	100%
O65050	Picea mariana	63%	100%
O65082	Picea mariana	63%	100%
O74895	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
O82528	Petunia hybrida	61%	100%
O82712	Quercus suber	39%	100%
P05748	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	100%
P30736	Chironomus tentans	59%	100%
P49403	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	41%	100%
P51417	Gallus gallus	62%	100%
P52818	Anopheles gambiae	61%	100%
P54060	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	48%	100%
P54780	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	59%	100%
P60618	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	43%	100%
P61313	Homo sapiens	59%	100%
P61314	Rattus norvegicus	59%	100%
P61367	Epinephelus coioides	59%	100%
P61368	Hydra vulgaris	57%	100%
P61369	Silurus asotus	58%	100%
P61370	Methanococcus maripaludis (strain S2 / LL)	45%	100%
P79324	Sus scrofa	59%	100%
P91374	Caenorhabditis elegans	61%	100%
Q0W2Z5	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	42%	100%
Q12ZC4	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	40%	100%
Q18K99	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	42%	100%
Q22A30	Tetrahymena thermophila (strain SB210)	60%	100%
Q2FT55	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	38%	100%
Q2NEY3	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	44%	100%
Q3IUG6	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	43%	100%
Q4JB20	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	45%	94%
Q4Q6S3	Leishmania major	100%	100%
Q4R5B2	Macaca fascicularis	59%	100%
Q5A6R1	Candida albicans (strain SC5314 / ATCC MYA-2876)	59%	100%
Q5EAD6	Bos taurus	59%	100%
Q5JH43	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	48%	100%
Q5NVE0	Pongo abelii	59%	100%
Q6L0P2	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	42%	100%
Q74MN8	Nanoarchaeum equitans (strain Kin4-M)	41%	100%
Q7T2N4	Silurus meridionalis	58%	100%
Q7T2N5	Tachysurus fulvidraco	58%	100%
Q7T3M9	Siniperca knerii	58%	100%
Q7T3N1	Mylopharyngodon piceus	57%	100%
Q7T3N2	Monopterus albus	59%	100%
Q7T3N3	Paramisgurnus dabryanus	57%	100%
Q7T3N4	Megalobrama amblycephala	57%	100%
Q7T3N6	Hypophthalmichthys molitrix	57%	100%
Q7T3N7	Cyprinus carpio	57%	100%
Q7T3N8	Ctenopharyngodon idella	58%	100%
Q7T3N9	Carassius auratus	57%	100%
Q7T3P0	Hypophthalmichthys nobilis	57%	100%
Q7T3P1	Anguilla japonica	58%	100%
Q86K01	Dictyostelium discoideum	61%	100%
Q8PTU5	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	43%	100%
Q8TPX0	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	43%	100%
Q8TYB3	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	44%	100%
Q8U2F9	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	48%	100%
Q8VYF1	Arabidopsis thaliana	64%	100%
Q8X034	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	59%	100%
Q8ZWD8	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	40%	100%
Q90YV2	Ictalurus punctatus	58%	100%
Q975G1	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	42%	95%
Q97BC1	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	42%	100%
Q9CZM2	Mus musculus	59%	100%
Q9HSL2	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	41%	100%
Q9N9V8	Leishmania infantum	100%	100%
Q9US22	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
Q9UXD0	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	39%	94%
Q9V0D2	Pyrococcus abyssi (strain GE5 / Orsay)	49%	100%
Q9XYC2	Faxonius limosus	56%	100%
Q9YBZ8	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	45%	91%