Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IIW8_LEIDO

TriTrypDb:

LdBPK_160140.1 , LdCL_160006300 , LDHU3_16.0150

Length:

208

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IIW8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IIW8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.626
CLV_NRD_NRD_1	121	123	PF00675	0.421
CLV_NRD_NRD_1	37	39	PF00675	0.463
CLV_NRD_NRD_1	68	70	PF00675	0.666
CLV_PCSK_KEX2_1	63	65	PF00082	0.577
CLV_PCSK_KEX2_1	67	69	PF00082	0.572
CLV_PCSK_PC1ET2_1	63	65	PF00082	0.567
CLV_PCSK_PC1ET2_1	67	69	PF00082	0.557
CLV_PCSK_PC7_1	64	70	PF00082	0.563
CLV_PCSK_SKI1_1	104	108	PF00082	0.571
CLV_PCSK_SKI1_1	122	126	PF00082	0.404
DEG_APCC_DBOX_1	114	122	PF00400	0.507
DEG_APCC_DBOX_1	68	76	PF00400	0.631
DEG_SCF_FBW7_1	161	168	PF00400	0.556
DOC_CYCLIN_RxL_1	116	130	PF00134	0.502
DOC_MAPK_gen_1	117	126	PF00069	0.500
DOC_MAPK_MEF2A_6	120	128	PF00069	0.504
DOC_USP7_MATH_1	163	167	PF00917	0.562
DOC_USP7_MATH_1	44	48	PF00917	0.573
DOC_USP7_UBL2_3	39	43	PF12436	0.565
DOC_USP7_UBL2_3	63	67	PF12436	0.485
DOC_WW_Pin1_4	140	145	PF00397	0.617
DOC_WW_Pin1_4	161	166	PF00397	0.554
LIG_14-3-3_CanoR_1	38	43	PF00244	0.457
LIG_14-3-3_CterR_2	204	208	PF00244	0.496
LIG_Actin_WH2_2	191	208	PF00022	0.450
LIG_deltaCOP1_diTrp_1	182	191	PF00928	0.547
LIG_FHA_1	165	171	PF00498	0.801
LIG_FHA_1	48	54	PF00498	0.559
LIG_FHA_1	94	100	PF00498	0.478
LIG_FHA_2	166	172	PF00498	0.605
LIG_FHA_2	2	8	PF00498	0.628
LIG_MYND_1	140	144	PF01753	0.617
LIG_SH2_NCK_1	30	34	PF00017	0.446
LIG_SH2_SRC	30	33	PF00017	0.491
LIG_SH3_3	76	82	PF00018	0.602
LIG_TRAF2_1	132	135	PF00917	0.576
LIG_TRAF2_1	180	183	PF00917	0.478
MOD_CK1_1	143	149	PF00069	0.631
MOD_CK1_1	47	53	PF00069	0.560
MOD_CK2_1	128	134	PF00069	0.470
MOD_CK2_1	15	21	PF00069	0.529
MOD_GlcNHglycan	130	133	PF01048	0.524
MOD_GlcNHglycan	155	159	PF01048	0.668
MOD_GlcNHglycan	96	99	PF01048	0.496
MOD_GSK3_1	161	168	PF00069	0.664
MOD_GSK3_1	174	181	PF00069	0.581
MOD_NEK2_1	1	6	PF00069	0.640
MOD_NEK2_1	198	203	PF00069	0.610
MOD_NEK2_1	94	99	PF00069	0.402
MOD_PK_1	80	86	PF00069	0.589
MOD_PKA_1	38	44	PF00069	0.404
MOD_PKA_1	63	69	PF00069	0.560
MOD_PKA_2	174	180	PF00069	0.618
MOD_PKA_2	63	69	PF00069	0.560
MOD_Plk_1	134	140	PF00069	0.552
MOD_Plk_4	165	171	PF00069	0.667
MOD_Plk_4	198	204	PF00069	0.506
MOD_ProDKin_1	140	146	PF00069	0.620
MOD_ProDKin_1	161	167	PF00069	0.555
TRG_ER_diArg_1	115	118	PF00400	0.642
TRG_ER_diArg_1	203	206	PF00400	0.465
TRG_NLS_MonoExtC_3	66	71	PF00514	0.500
TRG_NLS_MonoExtN_4	120	126	PF00514	0.438
TRG_NLS_MonoExtN_4	64	71	PF00514	0.498
TRG_Pf-PMV_PEXEL_1	10	14	PF00026	0.468
TRG_Pf-PMV_PEXEL_1	122	127	PF00026	0.464

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0H3	Leptomonas seymouri	33%	100%
A4HWR2	Leishmania infantum	97%	100%
E9AQG9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4QF07	Leishmania major	80%	100%