Chaperone protein DNAj, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IIN7_LEIDO

TriTrypDb:

LdBPK_354090.1 , LdCL_350046000 , LDHU3_35.5310

Length:

386

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IIN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IIN7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	46	50	PF00656	0.647
CLV_NRD_NRD_1	101	103	PF00675	0.448
CLV_NRD_NRD_1	123	125	PF00675	0.514
CLV_NRD_NRD_1	21	23	PF00675	0.379
CLV_NRD_NRD_1	213	215	PF00675	0.729
CLV_NRD_NRD_1	291	293	PF00675	0.686
CLV_PCSK_FUR_1	270	274	PF00082	0.676
CLV_PCSK_KEX2_1	101	103	PF00082	0.448
CLV_PCSK_KEX2_1	125	127	PF00082	0.589
CLV_PCSK_KEX2_1	21	23	PF00082	0.370
CLV_PCSK_KEX2_1	213	215	PF00082	0.759
CLV_PCSK_KEX2_1	25	27	PF00082	0.331
CLV_PCSK_KEX2_1	272	274	PF00082	0.684
CLV_PCSK_KEX2_1	291	293	PF00082	0.498
CLV_PCSK_KEX2_1	58	60	PF00082	0.700
CLV_PCSK_PC1ET2_1	125	127	PF00082	0.598
CLV_PCSK_PC1ET2_1	25	27	PF00082	0.441
CLV_PCSK_PC1ET2_1	272	274	PF00082	0.713
CLV_PCSK_PC1ET2_1	58	60	PF00082	0.700
CLV_PCSK_PC7_1	21	27	PF00082	0.332
CLV_PCSK_PC7_1	54	60	PF00082	0.637
CLV_PCSK_SKI1_1	21	25	PF00082	0.371
CLV_PCSK_SKI1_1	26	30	PF00082	0.317
CLV_PCSK_SKI1_1	377	381	PF00082	0.527
CLV_PCSK_SKI1_1	84	88	PF00082	0.453
DEG_APCC_DBOX_1	100	108	PF00400	0.429
DEG_Nend_Nbox_1	1	3	PF02207	0.453
DEG_SPOP_SBC_1	314	318	PF00917	0.705
DOC_ANK_TNKS_1	173	180	PF00023	0.616
DOC_MAPK_gen_1	21	31	PF00069	0.495
DOC_MAPK_MEF2A_6	22	31	PF00069	0.441
DOC_PP1_RVXF_1	375	381	PF00149	0.514
DOC_PP4_FxxP_1	253	256	PF00568	0.772
DOC_PP4_FxxP_1	380	383	PF00568	0.597
DOC_USP7_MATH_1	13	17	PF00917	0.441
DOC_USP7_MATH_1	337	341	PF00917	0.723
DOC_USP7_MATH_1	65	69	PF00917	0.590
DOC_USP7_MATH_1	75	79	PF00917	0.626
DOC_USP7_MATH_2	259	265	PF00917	0.648
DOC_WW_Pin1_4	150	155	PF00397	0.571
DOC_WW_Pin1_4	178	183	PF00397	0.711
DOC_WW_Pin1_4	199	204	PF00397	0.641
LIG_14-3-3_CanoR_1	157	163	PF00244	0.631
LIG_14-3-3_CanoR_1	250	256	PF00244	0.670
LIG_14-3-3_CanoR_1	283	293	PF00244	0.678
LIG_14-3-3_CanoR_1	347	351	PF00244	0.756
LIG_14-3-3_CanoR_1	377	383	PF00244	0.554
LIG_BIR_III_4	239	243	PF00653	0.602
LIG_BRCT_BRCA1_1	317	321	PF00533	0.706
LIG_BRCT_BRCA1_1	82	86	PF00533	0.681
LIG_FHA_1	373	379	PF00498	0.498
LIG_FHA_1	43	49	PF00498	0.705
LIG_LIR_Gen_1	106	115	PF02991	0.521
LIG_LIR_Gen_1	161	170	PF02991	0.579
LIG_LIR_Gen_1	4	13	PF02991	0.346
LIG_LIR_Gen_1	83	93	PF02991	0.467
LIG_LIR_Nem_3	106	112	PF02991	0.452
LIG_LIR_Nem_3	4	9	PF02991	0.346
LIG_LIR_Nem_3	83	89	PF02991	0.480
LIG_LIR_Nem_3	91	96	PF02991	0.350
LIG_MYND_1	203	207	PF01753	0.678
LIG_SH2_STAP1	105	109	PF00017	0.422
LIG_SH2_STAT3	366	369	PF00017	0.501
LIG_SH2_STAT5	103	106	PF00017	0.424
LIG_SH3_3	200	206	PF00018	0.684
LIG_SH3_3	253	259	PF00018	0.632
LIG_SH3_3	331	337	PF00018	0.732
LIG_SH3_3	357	363	PF00018	0.683
LIG_TRAF2_1	16	19	PF00917	0.441
LIG_WRC_WIRS_1	159	164	PF05994	0.549
MOD_CDK_SPxxK_3	150	157	PF00069	0.578
MOD_CK1_1	286	292	PF00069	0.708
MOD_CK1_1	327	333	PF00069	0.772
MOD_CK2_1	13	19	PF00069	0.332
MOD_CK2_1	160	166	PF00069	0.670
MOD_CK2_1	319	325	PF00069	0.775
MOD_CK2_1	330	336	PF00069	0.650
MOD_GlcNHglycan	15	18	PF01048	0.441
MOD_GlcNHglycan	325	329	PF01048	0.583
MOD_GlcNHglycan	336	340	PF01048	0.549
MOD_GlcNHglycan	37	40	PF01048	0.502
MOD_GlcNHglycan	63	66	PF01048	0.686
MOD_GSK3_1	160	167	PF00069	0.692
MOD_GSK3_1	282	289	PF00069	0.734
MOD_GSK3_1	291	298	PF00069	0.678
MOD_GSK3_1	315	322	PF00069	0.653
MOD_GSK3_1	323	330	PF00069	0.751
MOD_GSK3_1	35	42	PF00069	0.642
MOD_GSK3_1	368	375	PF00069	0.484
MOD_GSK3_1	61	68	PF00069	0.567
MOD_GSK3_1	80	87	PF00069	0.539
MOD_N-GLC_1	61	66	PF02516	0.592
MOD_NEK2_1	284	289	PF00069	0.646
MOD_NEK2_1	305	310	PF00069	0.626
MOD_NEK2_1	313	318	PF00069	0.661
MOD_NEK2_2	229	234	PF00069	0.661
MOD_PIKK_1	244	250	PF00454	0.730
MOD_PIKK_1	286	292	PF00454	0.728
MOD_PKA_1	291	297	PF00069	0.743
MOD_PKA_2	277	283	PF00069	0.698
MOD_PKA_2	291	297	PF00069	0.584
MOD_PKA_2	346	352	PF00069	0.736
MOD_PKB_1	124	132	PF00069	0.441
MOD_Plk_1	229	235	PF00069	0.720
MOD_Plk_1	372	378	PF00069	0.488
MOD_Plk_1	65	71	PF00069	0.581
MOD_Plk_2-3	354	360	PF00069	0.550
MOD_Plk_4	330	336	PF00069	0.611
MOD_ProDKin_1	150	156	PF00069	0.575
MOD_ProDKin_1	178	184	PF00069	0.713
MOD_ProDKin_1	199	205	PF00069	0.642
MOD_SUMO_rev_2	294	301	PF00179	0.707
TRG_ENDOCYTIC_2	109	112	PF00928	0.465
TRG_ENDOCYTIC_2	5	8	PF00928	0.334
TRG_ENDOCYTIC_2	93	96	PF00928	0.404
TRG_ER_diArg_1	101	103	PF00400	0.448
TRG_ER_diArg_1	20	22	PF00400	0.366
TRG_ER_diArg_1	291	293	PF00400	0.744
TRG_ER_diArg_1	52	55	PF00400	0.557
TRG_NES_CRM1_1	18	30	PF08389	0.451
TRG_Pf-PMV_PEXEL_1	102	106	PF00026	0.418
TRG_Pf-PMV_PEXEL_1	234	239	PF00026	0.682

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBL0	Leptomonas seymouri	30%	100%
A4HN74	Leishmania braziliensis	64%	100%
A4IBU2	Leishmania infantum	99%	100%
E9AFM9	Leishmania major	85%	100%
E9B6T2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%