Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IIJ1_LEIDO

TriTrypDb:

LdBPK_353470.1 , LdCL_350039700 , LDHU3_35.4550

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IIJ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IIJ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	124	126	PF00675	0.567
CLV_PCSK_KEX2_1	124	126	PF00082	0.567
CLV_PCSK_PC7_1	120	126	PF00082	0.565
DEG_Nend_UBRbox_1	1	4	PF02207	0.673
DEG_SPOP_SBC_1	54	58	PF00917	0.720
DOC_PP4_FxxP_1	10	13	PF00568	0.709
DOC_PP4_FxxP_1	75	78	PF00568	0.746
DOC_USP7_MATH_1	43	47	PF00917	0.757
DOC_USP7_MATH_1	54	58	PF00917	0.534
DOC_USP7_MATH_1	6	10	PF00917	0.736
DOC_USP7_MATH_1	97	101	PF00917	0.761
DOC_WW_Pin1_4	56	61	PF00397	0.755
DOC_WW_Pin1_4	85	90	PF00397	0.692
LIG_14-3-3_CanoR_1	145	151	PF00244	0.388
LIG_14-3-3_CanoR_1	2	10	PF00244	0.667
LIG_14-3-3_CanoR_1	52	62	PF00244	0.605
LIG_14-3-3_CanoR_1	91	97	PF00244	0.731
LIG_BRCT_BRCA1_1	35	39	PF00533	0.683
LIG_BRCT_BRCA1_1	71	75	PF00533	0.757
LIG_FHA_1	24	30	PF00498	0.616
LIG_FHA_1	93	99	PF00498	0.808
LIG_FHA_2	78	84	PF00498	0.727
LIG_FHA_2	99	105	PF00498	0.709
LIG_LIR_Apic_2	72	78	PF02991	0.750
LIG_LIR_Apic_2	9	13	PF02991	0.707
LIG_LIR_Gen_1	140	151	PF02991	0.537
LIG_LIR_Nem_3	140	146	PF02991	0.542
LIG_Pex14_2	10	14	PF04695	0.707
LIG_SH3_3	48	54	PF00018	0.595
LIG_SH3_3	59	65	PF00018	0.623
LIG_SH3_3	84	90	PF00018	0.603
LIG_SUMO_SIM_anti_2	173	180	PF11976	0.400
LIG_TRAF2_1	180	183	PF00917	0.671
LIG_WW_3	88	92	PF00397	0.677
MOD_CDK_SPxK_1	85	91	PF00069	0.674
MOD_CK1_1	100	106	PF00069	0.685
MOD_CK2_1	177	183	PF00069	0.622
MOD_CK2_1	77	83	PF00069	0.720
MOD_GlcNHglycan	179	182	PF01048	0.413
MOD_GSK3_1	14	21	PF00069	0.594
MOD_GSK3_1	173	180	PF00069	0.575
MOD_GSK3_1	65	72	PF00069	0.736
MOD_GSK3_1	73	80	PF00069	0.704
MOD_N-GLC_1	54	59	PF02516	0.720
MOD_NEK2_1	1	6	PF00069	0.701
MOD_NEK2_1	14	19	PF00069	0.587
MOD_NEK2_1	154	159	PF00069	0.378
MOD_NEK2_1	33	38	PF00069	0.715
MOD_NEK2_2	6	11	PF00069	0.719
MOD_PIKK_1	144	150	PF00454	0.565
MOD_PIKK_1	33	39	PF00454	0.715
MOD_PKA_2	1	7	PF00069	0.678
MOD_PKA_2	110	116	PF00069	0.586
MOD_PKA_2	144	150	PF00069	0.390
MOD_Plk_1	65	71	PF00069	0.601
MOD_Plk_4	137	143	PF00069	0.507
MOD_Plk_4	173	179	PF00069	0.578
MOD_ProDKin_1	56	62	PF00069	0.753
MOD_ProDKin_1	85	91	PF00069	0.696
TRG_ER_diArg_1	109	112	PF00400	0.579

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HN09	Leishmania braziliensis	68%	100%
A4IBN2	Leishmania infantum	99%	100%
E9AFG6	Leishmania major	89%	100%
E9B6M1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%