Amastin-like surface protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

tuzin-like protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IIC2_LEIDO

TriTrypDb:

LdBPK_341160.1 , LdCL_340017550

Length:

334

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IIC2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IIC2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	244	246	PF00675	0.748
CLV_PCSK_KEX2_1	244	246	PF00082	0.748
CLV_PCSK_SKI1_1	320	324	PF00082	0.794
DEG_APCC_DBOX_1	73	81	PF00400	0.790
DOC_CYCLIN_yCln2_LP_2	88	94	PF00134	0.791
DOC_PP2B_LxvP_1	88	91	PF13499	0.784
DOC_USP7_MATH_1	70	74	PF00917	0.647
DOC_USP7_MATH_1	9	13	PF00917	0.747
DOC_WW_Pin1_4	12	17	PF00397	0.749
DOC_WW_Pin1_4	314	319	PF00397	0.737
DOC_WW_Pin1_4	68	73	PF00397	0.793
LIG_14-3-3_CanoR_1	104	108	PF00244	0.788
LIG_14-3-3_CanoR_1	111	115	PF00244	0.680
LIG_14-3-3_CanoR_1	273	281	PF00244	0.674
LIG_14-3-3_CanoR_1	304	308	PF00244	0.559
LIG_14-3-3_CanoR_1	312	318	PF00244	0.606
LIG_APCC_ABBA_1	194	199	PF00400	0.801
LIG_BRCT_BRCA1_1	315	319	PF00533	0.738
LIG_FHA_1	28	34	PF00498	0.750
LIG_FHA_1	327	333	PF00498	0.737
LIG_Integrin_RGD_1	157	159	PF01839	0.776
LIG_Integrin_RGDW_4	157	160	PF00362	0.779
LIG_PDZ_Class_2	329	334	PF00595	0.737
LIG_SH2_STAP1	253	257	PF00017	0.644
LIG_SH2_STAT5	114	117	PF00017	0.690
LIG_SH2_STAT5	253	256	PF00017	0.621
LIG_SH2_STAT5	4	7	PF00017	0.738
LIG_SH3_1	13	19	PF00018	0.758
LIG_SH3_1	315	321	PF00018	0.740
LIG_SH3_2	16	21	PF14604	0.769
LIG_SH3_2	58	63	PF14604	0.800
LIG_SH3_3	13	19	PF00018	0.634
LIG_SH3_3	197	203	PF00018	0.735
LIG_SH3_3	315	321	PF00018	0.740
LIG_SH3_3	55	61	PF00018	0.802
LIG_SH3_3	75	81	PF00018	0.510
MOD_CDK_SPxK_1	314	320	PF00069	0.741
MOD_CDK_SPxK_1	68	74	PF00069	0.792
MOD_CK1_1	109	115	PF00069	0.778
MOD_CK1_1	12	18	PF00069	0.753
MOD_CK1_1	251	257	PF00069	0.737
MOD_GlcNHglycan	250	253	PF01048	0.785
MOD_GlcNHglycan	289	292	PF01048	0.636
MOD_GSK3_1	103	110	PF00069	0.785
MOD_GSK3_1	8	15	PF00069	0.721
MOD_NEK2_1	313	318	PF00069	0.763
MOD_PIKK_1	251	257	PF00454	0.737
MOD_PKA_2	100	106	PF00069	0.787
MOD_PKA_2	107	113	PF00069	0.682
MOD_PKA_2	243	249	PF00069	0.752
MOD_PKA_2	272	278	PF00069	0.669
MOD_PKA_2	287	293	PF00069	0.500
MOD_PKA_2	303	309	PF00069	0.603
MOD_Plk_4	110	116	PF00069	0.640
MOD_ProDKin_1	12	18	PF00069	0.753
MOD_ProDKin_1	314	320	PF00069	0.741
MOD_ProDKin_1	68	74	PF00069	0.792
TRG_DiLeu_BaLyEn_6	295	300	PF01217	0.671
TRG_ER_diArg_1	243	245	PF00400	0.764

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I9R8	Leishmania infantum	98%	100%