Zinc finger protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc finger protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8II84_LEIDO

TriTrypDb:

LdBPK_353550.1 , LdCL_350040500 , LDHU3_35.4650

Length:

212

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8II84

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8II84

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	3
GO:0043167	ion binding	2	3
GO:0043169	cation binding	3	3
GO:0046872	metal ion binding	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	72	76	PF00656	0.698
CLV_NRD_NRD_1	55	57	PF00675	0.625
CLV_PCSK_SKI1_1	107	111	PF00082	0.526
CLV_PCSK_SKI1_1	191	195	PF00082	0.674
CLV_PCSK_SKI1_1	96	100	PF00082	0.608
DOC_CYCLIN_yCln2_LP_2	167	173	PF00134	0.504
DOC_MAPK_DCC_7	165	173	PF00069	0.503
DOC_MAPK_MEF2A_6	107	115	PF00069	0.577
DOC_PP2B_LxvP_1	154	157	PF13499	0.651
DOC_USP7_MATH_1	30	34	PF00917	0.698
DOC_USP7_MATH_1	42	46	PF00917	0.731
DOC_WW_Pin1_4	87	92	PF00397	0.642
LIG_14-3-3_CanoR_1	102	107	PF00244	0.518
LIG_14-3-3_CanoR_1	31	38	PF00244	0.775
LIG_BIR_III_4	34	38	PF00653	0.728
LIG_BIR_III_4	77	81	PF00653	0.612
LIG_EVH1_1	154	158	PF00568	0.662
LIG_FHA_1	108	114	PF00498	0.577
LIG_FHA_1	133	139	PF00498	0.659
LIG_FHA_1	149	155	PF00498	0.623
LIG_FHA_1	196	202	PF00498	0.667
LIG_FHA_2	125	131	PF00498	0.760
LIG_FHA_2	177	183	PF00498	0.695
LIG_FHA_2	45	51	PF00498	0.694
LIG_GBD_Chelix_1	184	192	PF00786	0.562
LIG_LIR_Gen_1	110	117	PF02991	0.598
LIG_LIR_Gen_1	59	70	PF02991	0.595
LIG_LIR_Nem_3	110	115	PF02991	0.598
LIG_LIR_Nem_3	207	212	PF02991	0.594
LIG_LIR_Nem_3	59	65	PF02991	0.573
LIG_SH2_CRK	62	66	PF00017	0.724
LIG_SH2_GRB2like	62	65	PF00017	0.731
LIG_SH2_PTP2	112	115	PF00017	0.575
LIG_SH2_SRC	112	115	PF00017	0.606
LIG_SH2_STAT5	112	115	PF00017	0.575
LIG_SH2_STAT5	166	169	PF00017	0.611
LIG_SH3_1	152	158	PF00018	0.660
LIG_SH3_3	139	145	PF00018	0.632
LIG_SH3_3	152	158	PF00018	0.650
LIG_SH3_CIN85_PxpxPR_1	26	31	PF14604	0.693
LIG_SUMO_SIM_anti_2	169	175	PF11976	0.508
LIG_TYR_ITSM	108	115	PF00017	0.590
MOD_CK1_1	132	138	PF00069	0.598
MOD_CK2_1	124	130	PF00069	0.751
MOD_CK2_1	176	182	PF00069	0.602
MOD_CK2_1	44	50	PF00069	0.690
MOD_GlcNHglycan	162	165	PF01048	0.586
MOD_GlcNHglycan	26	29	PF01048	0.785
MOD_GSK3_1	132	139	PF00069	0.668
MOD_GSK3_1	191	198	PF00069	0.641
MOD_GSK3_1	81	88	PF00069	0.686
MOD_PKA_2	132	138	PF00069	0.656
MOD_PKA_2	30	36	PF00069	0.776
MOD_Plk_2-3	136	142	PF00069	0.662
MOD_Plk_4	107	113	PF00069	0.535
MOD_Plk_4	169	175	PF00069	0.537
MOD_ProDKin_1	87	93	PF00069	0.632
TRG_DiLeu_BaEn_1	95	100	PF01217	0.566
TRG_ENDOCYTIC_2	112	115	PF00928	0.606
TRG_ENDOCYTIC_2	62	65	PF00928	0.586
TRG_Pf-PMV_PEXEL_1	165	169	PF00026	0.615

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9N1	Leptomonas seymouri	50%	70%
A4HN19	Leishmania braziliensis	75%	100%
A4IBP0	Leishmania infantum	99%	100%
E9AFH4	Leishmania major	93%	100%
E9B6M9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%