Splicing_factor_ptsr1_interacting_protein_putativ e/GeneDB:LmjF.34.0495

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

splicing factor ptsr1 interacting protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8II79_LEIDO

TriTrypDb:

LdBPK_340520.1 , LdCL_340010400 , LDHU3_34.0710

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8II79

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8II79

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	137	139	PF00675	0.654
CLV_NRD_NRD_1	152	154	PF00675	0.727
CLV_NRD_NRD_1	164	166	PF00675	0.641
CLV_NRD_NRD_1	173	175	PF00675	0.590
CLV_NRD_NRD_1	200	202	PF00675	0.599
CLV_NRD_NRD_1	211	213	PF00675	0.604
CLV_NRD_NRD_1	224	226	PF00675	0.653
CLV_NRD_NRD_1	227	229	PF00675	0.625
CLV_NRD_NRD_1	243	245	PF00675	0.388
CLV_NRD_NRD_1	250	252	PF00675	0.508
CLV_PCSK_FUR_1	162	166	PF00082	0.644
CLV_PCSK_FUR_1	197	201	PF00082	0.601
CLV_PCSK_FUR_1	225	229	PF00082	0.649
CLV_PCSK_KEX2_1	137	139	PF00082	0.651
CLV_PCSK_KEX2_1	152	154	PF00082	0.736
CLV_PCSK_KEX2_1	162	164	PF00082	0.638
CLV_PCSK_KEX2_1	173	175	PF00082	0.656
CLV_PCSK_KEX2_1	197	199	PF00082	0.604
CLV_PCSK_KEX2_1	200	202	PF00082	0.593
CLV_PCSK_KEX2_1	211	213	PF00082	0.604
CLV_PCSK_KEX2_1	224	226	PF00082	0.653
CLV_PCSK_KEX2_1	227	229	PF00082	0.625
CLV_PCSK_KEX2_1	243	245	PF00082	0.388
CLV_PCSK_KEX2_1	249	251	PF00082	0.501
CLV_PCSK_SKI1_1	42	46	PF00082	0.494
DEG_Nend_UBRbox_2	1	3	PF02207	0.540
DOC_MAPK_DCC_7	51	61	PF00069	0.607
DOC_PP4_MxPP_1	55	58	PF00568	0.603
DOC_USP7_MATH_1	69	73	PF00917	0.605
DOC_USP7_UBL2_3	86	90	PF12436	0.622
DOC_WW_Pin1_4	109	114	PF00397	0.647
LIG_14-3-3_CanoR_1	178	187	PF00244	0.667
LIG_14-3-3_CanoR_1	211	217	PF00244	0.551
LIG_deltaCOP1_diTrp_1	20	25	PF00928	0.366
LIG_FHA_2	110	116	PF00498	0.599
LIG_FHA_2	127	133	PF00498	0.697
LIG_FHA_2	92	98	PF00498	0.614
LIG_LIR_Gen_1	23	33	PF02991	0.371
LIG_LIR_Gen_1	95	102	PF02991	0.619
LIG_LIR_Nem_3	20	24	PF02991	0.314
LIG_LIR_Nem_3	40	44	PF02991	0.464
LIG_LIR_Nem_3	7	11	PF02991	0.666
LIG_LIR_Nem_3	95	101	PF02991	0.618
LIG_NRP_CendR_1	256	257	PF00754	0.571
LIG_Pex14_1	21	25	PF04695	0.360
LIG_SH2_CRK	41	45	PF00017	0.476
LIG_SH2_CRK	8	12	PF00017	0.649
LIG_SH2_NCK_1	8	12	PF00017	0.525
LIG_SH2_SRC	8	11	PF00017	0.530
LIG_SH2_STAT5	24	27	PF00017	0.374
LIG_SH3_3	50	56	PF00018	0.595
LIG_TRAF2_1	168	171	PF00917	0.581
LIG_TRAF2_1	218	221	PF00917	0.637
LIG_WW_1	5	8	PF00397	0.504
LIG_WW_2	57	60	PF00397	0.618
MOD_CDK_SPK_2	109	114	PF00069	0.647
MOD_CK1_1	100	106	PF00069	0.600
MOD_CK1_1	108	114	PF00069	0.632
MOD_CK1_1	182	188	PF00069	0.715
MOD_CK1_1	190	196	PF00069	0.624
MOD_CK1_1	219	225	PF00069	0.669
MOD_CK1_1	232	238	PF00069	0.513
MOD_CK2_1	165	171	PF00069	0.640
MOD_CK2_1	215	221	PF00069	0.637
MOD_CK2_1	89	95	PF00069	0.555
MOD_GlcNHglycan	107	110	PF01048	0.667
MOD_GlcNHglycan	192	195	PF01048	0.718
MOD_GlcNHglycan	201	204	PF01048	0.592
MOD_GlcNHglycan	231	234	PF01048	0.628
MOD_GlcNHglycan	71	74	PF01048	0.636
MOD_GSK3_1	104	111	PF00069	0.604
MOD_GSK3_1	133	140	PF00069	0.717
MOD_GSK3_1	178	185	PF00069	0.669
MOD_GSK3_1	188	195	PF00069	0.678
MOD_GSK3_1	211	218	PF00069	0.731
MOD_GSK3_1	227	234	PF00069	0.623
MOD_GSK3_1	63	70	PF00069	0.811
MOD_GSK3_1	96	103	PF00069	0.580
MOD_NEK2_1	101	106	PF00069	0.656
MOD_PIKK_1	63	69	PF00454	0.642
MOD_PKA_1	137	143	PF00069	0.723
MOD_PKA_1	199	205	PF00069	0.648
MOD_PKA_1	211	217	PF00069	0.639
MOD_PKA_1	227	233	PF00069	0.625
MOD_PKA_2	133	139	PF00069	0.755
MOD_PKA_2	156	162	PF00069	0.777
MOD_PKA_2	182	188	PF00069	0.660
MOD_PKA_2	199	205	PF00069	0.684
MOD_PKA_2	210	216	PF00069	0.637
MOD_PKA_2	227	233	PF00069	0.625
MOD_PKB_1	163	171	PF00069	0.732
MOD_PKB_1	176	184	PF00069	0.561
MOD_PKB_1	197	205	PF00069	0.650
MOD_PKB_1	225	233	PF00069	0.631
MOD_Plk_1	96	102	PF00069	0.597
MOD_Plk_2-3	156	162	PF00069	0.638
MOD_Plk_4	97	103	PF00069	0.625
MOD_ProDKin_1	109	115	PF00069	0.649
MOD_SUMO_rev_2	82	88	PF00179	0.616
TRG_ENDOCYTIC_2	27	30	PF00928	0.511
TRG_ENDOCYTIC_2	41	44	PF00928	0.338
TRG_ENDOCYTIC_2	8	11	PF00928	0.603
TRG_ER_diArg_1	152	155	PF00400	0.695
TRG_ER_diArg_1	162	165	PF00400	0.644
TRG_ER_diArg_1	173	176	PF00400	0.655
TRG_ER_diArg_1	197	200	PF00400	0.654
TRG_ER_diArg_1	224	226	PF00400	0.599
TRG_ER_diArg_1	248	251	PF00400	0.492
TRG_ER_diArg_1	255	257	PF00400	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HR54	Leptomonas seymouri	46%	100%
A4I9M0	Leishmania infantum	100%	100%
D0A1Y5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	67%
E9B4L8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4Q3F8	Leishmania major	94%	100%