LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8II27_LEIDO
TriTrypDb:
LdBPK_131160.1 , LdCL_130017000 , LDHU3_13.1420
Length:
192

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5
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Expansion

Sequence features

A0A3Q8II27
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8II27

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 138 142 PF00656 0.755
CLV_NRD_NRD_1 135 137 PF00675 0.490
CLV_PCSK_KEX2_1 135 137 PF00082 0.487
CLV_PCSK_KEX2_1 6 8 PF00082 0.518
CLV_PCSK_PC1ET2_1 135 137 PF00082 0.507
CLV_PCSK_PC1ET2_1 6 8 PF00082 0.436
CLV_PCSK_SKI1_1 61 65 PF00082 0.356
DEG_APCC_DBOX_1 60 68 PF00400 0.272
DOC_MAPK_gen_1 95 105 PF00069 0.303
DOC_MAPK_MEF2A_6 98 106 PF00069 0.346
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Homologs

ProteinTaxonomySequence identityCoverage
A4H7A9 Leishmania braziliensis 52% 100%
A4HVQ4 Leishmania infantum 99% 100%
E9APF0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
Q4QG28 Leishmania major 83% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS