MYND finger containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IHZ5_LEIDO

TriTrypDb:

LdBPK_332550.1 , LdCL_330032600 , LDHU3_33.3640

Length:

713

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHZ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHZ5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	4
GO:0043167	ion binding	2	4
GO:0043169	cation binding	3	4
GO:0046872	metal ion binding	4	4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.581
CLV_C14_Caspase3-7	421	425	PF00656	0.825
CLV_NRD_NRD_1	190	192	PF00675	0.828
CLV_NRD_NRD_1	371	373	PF00675	0.678
CLV_NRD_NRD_1	45	47	PF00675	0.799
CLV_NRD_NRD_1	455	457	PF00675	0.860
CLV_NRD_NRD_1	55	57	PF00675	0.654
CLV_NRD_NRD_1	656	658	PF00675	0.517
CLV_NRD_NRD_1	711	713	PF00675	0.559
CLV_PCSK_FUR_1	369	373	PF00082	0.677
CLV_PCSK_KEX2_1	189	191	PF00082	0.830
CLV_PCSK_KEX2_1	371	373	PF00082	0.635
CLV_PCSK_KEX2_1	45	47	PF00082	0.799
CLV_PCSK_KEX2_1	454	456	PF00082	0.874
CLV_PCSK_KEX2_1	55	57	PF00082	0.654
CLV_PCSK_KEX2_1	673	675	PF00082	0.695
CLV_PCSK_PC1ET2_1	673	675	PF00082	0.695
CLV_PCSK_PC7_1	669	675	PF00082	0.692
CLV_PCSK_SKI1_1	130	134	PF00082	0.785
CLV_PCSK_SKI1_1	617	621	PF00082	0.652
CLV_PCSK_SKI1_1	652	656	PF00082	0.620
CLV_PCSK_SKI1_1	699	703	PF00082	0.496
CLV_PCSK_SKI1_1	86	90	PF00082	0.775
DEG_SCF_FBW7_1	132	137	PF00400	0.708
DEG_SPOP_SBC_1	135	139	PF00917	0.654
DOC_CYCLIN_yCln2_LP_2	160	166	PF00134	0.817
DOC_MAPK_gen_1	657	666	PF00069	0.473
DOC_MAPK_MEF2A_6	660	668	PF00069	0.485
DOC_MAPK_RevD_3	659	674	PF00069	0.497
DOC_PP2B_LxvP_1	6	9	PF13499	0.723
DOC_USP7_MATH_1	109	113	PF00917	0.647
DOC_USP7_MATH_1	232	236	PF00917	0.745
DOC_USP7_MATH_1	440	444	PF00917	0.660
DOC_USP7_MATH_1	99	103	PF00917	0.760
DOC_WW_Pin1_4	1	6	PF00397	0.776
DOC_WW_Pin1_4	130	135	PF00397	0.834
DOC_WW_Pin1_4	136	141	PF00397	0.727
DOC_WW_Pin1_4	27	32	PF00397	0.719
DOC_WW_Pin1_4	315	320	PF00397	0.474
DOC_WW_Pin1_4	40	45	PF00397	0.626
DOC_WW_Pin1_4	445	450	PF00397	0.676
DOC_WW_Pin1_4	47	52	PF00397	0.543
DOC_WW_Pin1_4	484	489	PF00397	0.779
DOC_WW_Pin1_4	88	93	PF00397	0.735
LIG_14-3-3_CanoR_1	205	210	PF00244	0.820
LIG_14-3-3_CanoR_1	261	267	PF00244	0.598
LIG_14-3-3_CanoR_1	436	440	PF00244	0.779
LIG_14-3-3_CanoR_1	460	469	PF00244	0.835
LIG_14-3-3_CanoR_1	500	509	PF00244	0.821
LIG_14-3-3_CanoR_1	529	533	PF00244	0.784
LIG_14-3-3_CanoR_1	56	65	PF00244	0.672
LIG_14-3-3_CanoR_1	573	577	PF00244	0.851
LIG_14-3-3_CanoR_1	604	612	PF00244	0.615
LIG_Actin_WH2_2	179	197	PF00022	0.649
LIG_BRCT_BRCA1_1	474	478	PF00533	0.851
LIG_FHA_1	108	114	PF00498	0.667
LIG_FHA_1	131	137	PF00498	0.833
LIG_FHA_1	171	177	PF00498	0.633
LIG_FHA_1	446	452	PF00498	0.668
LIG_FHA_1	536	542	PF00498	0.705
LIG_FHA_1	700	706	PF00498	0.541
LIG_FHA_2	169	175	PF00498	0.724
LIG_FHA_2	624	630	PF00498	0.748
LIG_Integrin_RGD_1	393	395	PF01839	0.825
LIG_LIR_Apic_2	270	276	PF02991	0.621
LIG_LIR_Apic_2	492	497	PF02991	0.802
LIG_LIR_Gen_1	342	349	PF02991	0.524
LIG_LIR_Gen_1	686	697	PF02991	0.624
LIG_LIR_Nem_3	250	254	PF02991	0.760
LIG_LIR_Nem_3	342	348	PF02991	0.524
LIG_LIR_Nem_3	475	481	PF02991	0.845
LIG_LIR_Nem_3	686	692	PF02991	0.674
LIG_PCNA_PIPBox_1	630	639	PF02747	0.691
LIG_PCNA_yPIPBox_3	628	637	PF02747	0.707
LIG_SH2_CRK	273	277	PF00017	0.608
LIG_SH2_CRK	345	349	PF00017	0.372
LIG_SH2_NCK_1	494	498	PF00017	0.802
LIG_SH2_SRC	494	497	PF00017	0.799
LIG_SH2_STAT5	282	285	PF00017	0.555
LIG_SH2_STAT5	333	336	PF00017	0.524
LIG_SH2_STAT5	605	608	PF00017	0.636
LIG_SH3_1	195	201	PF00018	0.769
LIG_SH3_3	195	201	PF00018	0.769
LIG_SH3_3	384	390	PF00018	0.665
LIG_SH3_3	574	580	PF00018	0.661
LIG_SH3_3	619	625	PF00018	0.574
LIG_SUMO_SIM_anti_2	610	616	PF11976	0.651
LIG_WW_3	8	12	PF00397	0.759
MOD_CDC14_SPxK_1	4	7	PF00782	0.770
MOD_CDC14_SPxK_1	452	455	PF00782	0.800
MOD_CDK_SPK_2	136	141	PF00069	0.649
MOD_CDK_SPK_2	40	45	PF00069	0.738
MOD_CDK_SPK_2	449	454	PF00069	0.792
MOD_CDK_SPK_2	47	52	PF00069	0.673
MOD_CDK_SPxK_1	1	7	PF00069	0.779
MOD_CDK_SPxK_1	40	46	PF00069	0.758
MOD_CDK_SPxK_1	449	455	PF00069	0.771
MOD_CDK_SPxK_1	484	490	PF00069	0.660
MOD_CDK_SPxxK_3	136	143	PF00069	0.830
MOD_CDK_SPxxK_3	449	456	PF00069	0.675
MOD_CK1_1	16	22	PF00069	0.791
MOD_CK1_1	193	199	PF00069	0.665
MOD_CK1_1	212	218	PF00069	0.652
MOD_CK1_1	224	230	PF00069	0.604
MOD_CK1_1	235	241	PF00069	0.681
MOD_CK1_1	247	253	PF00069	0.575
MOD_CK1_1	38	44	PF00069	0.728
MOD_CK1_1	50	56	PF00069	0.665
MOD_CK1_1	528	534	PF00069	0.826
MOD_CK1_1	57	63	PF00069	0.562
MOD_CK1_1	597	603	PF00069	0.811
MOD_CK1_1	607	613	PF00069	0.634
MOD_CK2_1	410	416	PF00069	0.708
MOD_CK2_1	420	426	PF00069	0.677
MOD_CK2_1	440	446	PF00069	0.501
MOD_CK2_1	607	613	PF00069	0.781
MOD_Cter_Amidation	187	190	PF01082	0.817
MOD_Cter_Amidation	671	674	PF01082	0.691
MOD_DYRK1A_RPxSP_1	27	31	PF00069	0.689
MOD_GlcNHglycan	150	153	PF01048	0.830
MOD_GlcNHglycan	18	21	PF01048	0.792
MOD_GlcNHglycan	186	189	PF01048	0.715
MOD_GlcNHglycan	202	205	PF01048	0.581
MOD_GlcNHglycan	218	221	PF01048	0.548
MOD_GlcNHglycan	22	25	PF01048	0.740
MOD_GlcNHglycan	223	226	PF01048	0.717
MOD_GlcNHglycan	234	237	PF01048	0.531
MOD_GlcNHglycan	246	249	PF01048	0.583
MOD_GlcNHglycan	383	386	PF01048	0.652
MOD_GlcNHglycan	406	409	PF01048	0.754
MOD_GlcNHglycan	420	423	PF01048	0.614
MOD_GlcNHglycan	430	433	PF01048	0.721
MOD_GlcNHglycan	47	50	PF01048	0.771
MOD_GlcNHglycan	472	475	PF01048	0.848
MOD_GlcNHglycan	549	552	PF01048	0.829
MOD_GlcNHglycan	56	59	PF01048	0.681
MOD_GlcNHglycan	62	65	PF01048	0.608
MOD_GlcNHglycan	647	652	PF01048	0.504
MOD_GlcNHglycan	81	84	PF01048	0.637
MOD_GSK3_1	130	137	PF00069	0.783
MOD_GSK3_1	144	151	PF00069	0.563
MOD_GSK3_1	164	171	PF00069	0.489
MOD_GSK3_1	205	212	PF00069	0.759
MOD_GSK3_1	231	238	PF00069	0.760
MOD_GSK3_1	25	32	PF00069	0.588
MOD_GSK3_1	315	322	PF00069	0.441
MOD_GSK3_1	348	355	PF00069	0.526
MOD_GSK3_1	416	423	PF00069	0.686
MOD_GSK3_1	426	433	PF00069	0.695
MOD_GSK3_1	445	452	PF00069	0.549
MOD_GSK3_1	460	467	PF00069	0.821
MOD_GSK3_1	498	505	PF00069	0.725
MOD_GSK3_1	50	57	PF00069	0.745
MOD_GSK3_1	537	544	PF00069	0.757
MOD_GSK3_1	568	575	PF00069	0.690
MOD_GSK3_1	593	600	PF00069	0.711
MOD_GSK3_1	60	67	PF00069	0.647
MOD_GSK3_1	9	16	PF00069	0.744
MOD_LATS_1	418	424	PF00433	0.842
MOD_LATS_1	458	464	PF00433	0.806
MOD_LATS_1	602	608	PF00433	0.627
MOD_N-GLC_1	107	112	PF02516	0.712
MOD_N-GLC_1	115	120	PF02516	0.638
MOD_N-GLC_1	244	249	PF02516	0.747
MOD_N-GLC_1	401	406	PF02516	0.819
MOD_N-GLC_1	535	540	PF02516	0.726
MOD_N-GLC_1	547	552	PF02516	0.740
MOD_N-GLC_2	260	262	PF02516	0.560
MOD_NEK2_1	207	212	PF00069	0.688
MOD_NEK2_1	221	226	PF00069	0.697
MOD_NEK2_1	410	415	PF00069	0.841
MOD_NEK2_1	430	435	PF00069	0.490
MOD_NEK2_1	541	546	PF00069	0.843
MOD_NEK2_1	561	566	PF00069	0.705
MOD_NEK2_1	572	577	PF00069	0.608
MOD_NEK2_1	637	642	PF00069	0.667
MOD_NEK2_2	109	114	PF00069	0.668
MOD_NEK2_2	239	244	PF00069	0.565
MOD_NEK2_2	319	324	PF00069	0.524
MOD_NEK2_2	477	482	PF00069	0.717
MOD_NEK2_2	537	542	PF00069	0.837
MOD_PIKK_1	317	323	PF00454	0.524
MOD_PIKK_1	373	379	PF00454	0.805
MOD_PIKK_1	464	470	PF00454	0.740
MOD_PIKK_1	50	56	PF00454	0.735
MOD_PIKK_1	502	508	PF00454	0.845
MOD_PIKK_1	549	555	PF00454	0.817
MOD_PIKK_1	572	578	PF00454	0.791
MOD_PIKK_1	607	613	PF00454	0.781
MOD_PIKK_1	699	705	PF00454	0.545
MOD_PIKK_1	90	96	PF00454	0.706
MOD_PK_1	205	211	PF00069	0.818
MOD_PKA_1	190	196	PF00069	0.664
MOD_PKA_1	45	51	PF00069	0.772
MOD_PKA_1	454	460	PF00069	0.865
MOD_PKA_1	699	705	PF00069	0.545
MOD_PKA_2	190	196	PF00069	0.664
MOD_PKA_2	212	218	PF00069	0.795
MOD_PKA_2	260	266	PF00069	0.557
MOD_PKA_2	388	394	PF00069	0.771
MOD_PKA_2	416	422	PF00069	0.794
MOD_PKA_2	435	441	PF00069	0.559
MOD_PKA_2	45	51	PF00069	0.772
MOD_PKA_2	454	460	PF00069	0.556
MOD_PKA_2	489	495	PF00069	0.736
MOD_PKA_2	499	505	PF00069	0.619
MOD_PKA_2	528	534	PF00069	0.780
MOD_PKA_2	54	60	PF00069	0.684
MOD_PKA_2	572	578	PF00069	0.715
MOD_PKA_2	678	684	PF00069	0.539
MOD_PKB_1	27	35	PF00069	0.687
MOD_Plk_1	341	347	PF00069	0.399
MOD_Plk_1	426	432	PF00069	0.647
MOD_Plk_1	615	621	PF00069	0.601
MOD_Plk_4	101	107	PF00069	0.759
MOD_Plk_4	144	150	PF00069	0.846
MOD_Plk_4	239	245	PF00069	0.562
MOD_Plk_4	537	543	PF00069	0.838
MOD_Plk_4	594	600	PF00069	0.810
MOD_Plk_4	678	684	PF00069	0.539
MOD_ProDKin_1	1	7	PF00069	0.779
MOD_ProDKin_1	130	136	PF00069	0.833
MOD_ProDKin_1	27	33	PF00069	0.718
MOD_ProDKin_1	315	321	PF00069	0.474
MOD_ProDKin_1	40	46	PF00069	0.628
MOD_ProDKin_1	445	451	PF00069	0.678
MOD_ProDKin_1	47	53	PF00069	0.542
MOD_ProDKin_1	484	490	PF00069	0.785
MOD_ProDKin_1	88	94	PF00069	0.734
MOD_SUMO_for_1	683	686	PF00179	0.670
MOD_SUMO_rev_2	68	74	PF00179	0.672
TRG_DiLeu_BaEn_3	677	683	PF01217	0.666
TRG_DiLeu_BaLyEn_6	556	561	PF01217	0.666
TRG_ENDOCYTIC_2	345	348	PF00928	0.526
TRG_ER_diArg_1	140	143	PF00400	0.657
TRG_ER_diArg_1	189	191	PF00400	0.707
TRG_ER_diArg_1	368	371	PF00400	0.804
TRG_ER_diArg_1	44	46	PF00400	0.789
TRG_ER_diArg_1	453	456	PF00400	0.857
TRG_Pf-PMV_PEXEL_1	641	645	PF00026	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AHR0	Leishmania infantum	99%	100%
E9B481	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	98%
Q4Q3U5	Leishmania major	84%	100%