Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IHV8_LEIDO

TriTrypDb:

LdCL_130005700 , LDHU3_13.0090

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHV8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHV8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	104	106	PF00675	0.616
CLV_NRD_NRD_1	151	153	PF00675	0.563
CLV_NRD_NRD_1	75	77	PF00675	0.683
CLV_PCSK_FUR_1	73	77	PF00082	0.577
CLV_PCSK_KEX2_1	103	105	PF00082	0.643
CLV_PCSK_KEX2_1	151	153	PF00082	0.563
CLV_PCSK_KEX2_1	75	77	PF00082	0.683
CLV_PCSK_SKI1_1	137	141	PF00082	0.742
CLV_PCSK_SKI1_1	98	102	PF00082	0.604
DEG_Nend_UBRbox_2	1	3	PF02207	0.721
DOC_CKS1_1	68	73	PF01111	0.610
DOC_PP4_FxxP_1	186	189	PF00568	0.732
DOC_USP7_MATH_1	166	170	PF00917	0.661
DOC_USP7_MATH_1	192	196	PF00917	0.703
DOC_USP7_MATH_1	38	42	PF00917	0.732
DOC_WW_Pin1_4	130	135	PF00397	0.717
DOC_WW_Pin1_4	172	177	PF00397	0.630
DOC_WW_Pin1_4	185	190	PF00397	0.665
DOC_WW_Pin1_4	49	54	PF00397	0.778
DOC_WW_Pin1_4	67	72	PF00397	0.620
DOC_WW_Pin1_4	8	13	PF00397	0.613
LIG_14-3-3_CanoR_1	75	82	PF00244	0.596
LIG_BRCT_BRCA1_1	182	186	PF00533	0.630
LIG_Clathr_ClatBox_1	29	33	PF01394	0.514
LIG_FHA_2	32	38	PF00498	0.715
LIG_FHA_2	94	100	PF00498	0.648
LIG_LIR_Apic_2	183	189	PF02991	0.726
LIG_PDZ_Class_1	191	196	PF00595	0.766
LIG_Pex14_2	182	186	PF04695	0.630
LIG_SH2_STAT3	184	187	PF00017	0.634
LIG_SH2_STAT5	114	117	PF00017	0.754
LIG_SH2_STAT5	164	167	PF00017	0.658
LIG_SH3_3	173	179	PF00018	0.618
LIG_SH3_3	4	10	PF00018	0.615
LIG_SH3_3	65	71	PF00018	0.639
LIG_SUMO_SIM_par_1	28	34	PF11976	0.514
MOD_CDK_SPK_2	172	177	PF00069	0.623
MOD_CDK_SPK_2	49	54	PF00069	0.651
MOD_CDK_SPxK_1	67	73	PF00069	0.618
MOD_CDK_SPxxK_3	130	137	PF00069	0.715
MOD_CDK_SPxxK_3	8	15	PF00069	0.729
MOD_CK1_1	169	175	PF00069	0.646
MOD_CK1_1	180	186	PF00069	0.625
MOD_CK1_1	188	194	PF00069	0.652
MOD_CK1_1	8	14	PF00069	0.750
MOD_CK2_1	31	37	PF00069	0.636
MOD_CK2_1	93	99	PF00069	0.596
MOD_DYRK1A_RPxSP_1	67	71	PF00069	0.628
MOD_GlcNHglycan	190	193	PF01048	0.664
MOD_GlcNHglycan	77	80	PF01048	0.663
MOD_GSK3_1	104	111	PF00069	0.654
MOD_GSK3_1	160	167	PF00069	0.642
MOD_GSK3_1	188	195	PF00069	0.688
MOD_GSK3_1	43	50	PF00069	0.771
MOD_GSK3_1	63	70	PF00069	0.745
MOD_N-GLC_1	43	48	PF02516	0.742
MOD_NEK2_1	147	152	PF00069	0.552
MOD_NEK2_1	20	25	PF00069	0.687
MOD_NEK2_2	31	36	PF00069	0.617
MOD_PK_1	108	114	PF00069	0.665
MOD_PKA_1	104	110	PF00069	0.624
MOD_PKA_1	75	81	PF00069	0.676
MOD_PKA_2	104	110	PF00069	0.624
MOD_PKA_2	75	81	PF00069	0.676
MOD_PKB_1	73	81	PF00069	0.567
MOD_Plk_1	108	114	PF00069	0.665
MOD_Plk_1	47	53	PF00069	0.654
MOD_ProDKin_1	130	136	PF00069	0.716
MOD_ProDKin_1	172	178	PF00069	0.627
MOD_ProDKin_1	185	191	PF00069	0.668
MOD_ProDKin_1	49	55	PF00069	0.775
MOD_ProDKin_1	67	73	PF00069	0.618
MOD_ProDKin_1	8	14	PF00069	0.613
MOD_SUMO_rev_2	93	102	PF00179	0.702
TRG_ENDOCYTIC_2	16	19	PF00928	0.632
TRG_ENDOCYTIC_2	82	85	PF00928	0.543
TRG_ER_diArg_1	102	105	PF00400	0.648
TRG_ER_diArg_1	73	76	PF00400	0.583
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.638

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0F4	Leptomonas seymouri	52%	92%
A4HVE3	Leishmania infantum	100%	100%
E9AP41	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%