Ribose-phosphate diphosphokinase family protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphoribosylpyrophosphate synthetase, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IHV7_LEIDO

TriTrypDb:

LdBPK_365630.1 , LdCL_360063700 , LDHU3_36.7500

Length:

358

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 75

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 30
NetGPI	no	yes: 0, no: 30

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	4
GO:0002189	ribose phosphate diphosphokinase complex	5	3
GO:0005737	cytoplasm	2	3
GO:0032991	protein-containing complex	1	3
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	3
GO:1902494	catalytic complex	2	3
GO:1990234	transferase complex	3	3

Expansion

Sequence features

A0A3Q8IHV7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHV7

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	31
GO:0006725	cellular aromatic compound metabolic process	3	31
GO:0006753	nucleoside phosphate metabolic process	4	31
GO:0006793	phosphorus metabolic process	3	31
GO:0006796	phosphate-containing compound metabolic process	4	31
GO:0006807	nitrogen compound metabolic process	2	31
GO:0008152	metabolic process	1	31
GO:0009058	biosynthetic process	2	31
GO:0009117	nucleotide metabolic process	5	31
GO:0009165	nucleotide biosynthetic process	6	31
GO:0009987	cellular process	1	31
GO:0016310	phosphorylation	5	4
GO:0018130	heterocycle biosynthetic process	4	31
GO:0019438	aromatic compound biosynthetic process	4	31
GO:0019637	organophosphate metabolic process	3	31
GO:0034641	cellular nitrogen compound metabolic process	3	31
GO:0034654	nucleobase-containing compound biosynthetic process	4	31
GO:0044237	cellular metabolic process	2	31
GO:0044238	primary metabolic process	2	31
GO:0044249	cellular biosynthetic process	3	31
GO:0044271	cellular nitrogen compound biosynthetic process	4	31
GO:0044281	small molecule metabolic process	2	31
GO:0046483	heterocycle metabolic process	3	31
GO:0055086	nucleobase-containing small molecule metabolic process	3	31
GO:0071704	organic substance metabolic process	2	31
GO:0090407	organophosphate biosynthetic process	4	31
GO:1901293	nucleoside phosphate biosynthetic process	5	31
GO:1901360	organic cyclic compound metabolic process	3	31
GO:1901362	organic cyclic compound biosynthetic process	4	31
GO:1901576	organic substance biosynthetic process	3	31
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	6	3
GO:0006163	purine nucleotide metabolic process	5	3
GO:0006164	purine nucleotide biosynthetic process	6	3
GO:0019693	ribose phosphate metabolic process	4	3
GO:0046390	ribose phosphate biosynthetic process	5	3
GO:0046391	5-phosphoribose 1-diphosphate metabolic process	5	3
GO:0072521	purine-containing compound metabolic process	4	3
GO:0072522	purine-containing compound biosynthetic process	5	3
GO:1901135	carbohydrate derivative metabolic process	3	3
GO:1901137	carbohydrate derivative biosynthetic process	4	3
GO:1901564	organonitrogen compound metabolic process	3	3
GO:1901566	organonitrogen compound biosynthetic process	4	3

Molecular functions
Term	Name	Level	Count
GO:0000287	magnesium ion binding	5	31
GO:0003824	catalytic activity	1	31
GO:0004749	ribose phosphate diphosphokinase activity	5	31
GO:0005488	binding	1	31
GO:0016301	kinase activity	4	4
GO:0016740	transferase activity	2	31
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	31
GO:0016778	diphosphotransferase activity	4	31
GO:0043167	ion binding	2	31
GO:0043169	cation binding	3	31
GO:0046872	metal ion binding	4	31

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	110	112	PF00675	0.344
CLV_NRD_NRD_1	192	194	PF00675	0.440
CLV_NRD_NRD_1	209	211	PF00675	0.566
CLV_NRD_NRD_1	95	97	PF00675	0.332
CLV_PCSK_FUR_1	190	194	PF00082	0.434
CLV_PCSK_KEX2_1	192	194	PF00082	0.471
CLV_PCSK_KEX2_1	208	210	PF00082	0.527
CLV_PCSK_KEX2_1	95	97	PF00082	0.314
CLV_PCSK_PC1ET2_1	208	210	PF00082	0.520
CLV_PCSK_SKI1_1	126	130	PF00082	0.337
CLV_PCSK_SKI1_1	171	175	PF00082	0.474
CLV_PCSK_SKI1_1	202	206	PF00082	0.455
CLV_PCSK_SKI1_1	300	304	PF00082	0.380
DEG_Nend_UBRbox_2	1	3	PF02207	0.776
DOC_CYCLIN_yCln2_LP_2	30	36	PF00134	0.489
DOC_MAPK_gen_1	111	119	PF00069	0.523
DOC_MAPK_gen_1	296	304	PF00069	0.531
DOC_PP2B_LxvP_1	30	33	PF13499	0.514
DOC_PP4_FxxP_1	267	270	PF00568	0.624
DOC_WW_Pin1_4	156	161	PF00397	0.486
DOC_WW_Pin1_4	171	176	PF00397	0.567
LIG_14-3-3_CanoR_1	116	124	PF00244	0.542
LIG_14-3-3_CanoR_1	126	133	PF00244	0.547
LIG_14-3-3_CanoR_1	274	282	PF00244	0.553
LIG_14-3-3_CanoR_1	317	324	PF00244	0.547
LIG_Actin_WH2_2	75	92	PF00022	0.528
LIG_BRCT_BRCA1_1	160	164	PF00533	0.503
LIG_FHA_1	112	118	PF00498	0.538
LIG_FHA_1	136	142	PF00498	0.376
LIG_FHA_1	261	267	PF00498	0.538
LIG_FHA_1	285	291	PF00498	0.516
LIG_FHA_1	86	92	PF00498	0.539
LIG_FHA_2	274	280	PF00498	0.569
LIG_Integrin_RGD_1	56	58	PF01839	0.323
LIG_LIR_LC3C_4	176	180	PF02991	0.472
LIG_LIR_Nem_3	161	167	PF02991	0.448
LIG_MAD2	12	20	PF02301	0.523
LIG_PCNA_yPIPBox_3	76	90	PF02747	0.534
LIG_SH2_STAT3	106	109	PF00017	0.538
LIG_SH2_STAT3	167	170	PF00017	0.594
LIG_SH2_STAT5	167	170	PF00017	0.503
LIG_SH2_STAT5	29	32	PF00017	0.624
LIG_SH3_3	177	183	PF00018	0.467
LIG_SH3_3	324	330	PF00018	0.695
LIG_SH3_3	59	65	PF00018	0.534
LIG_SUMO_SIM_anti_2	176	182	PF11976	0.389
LIG_SUMO_SIM_anti_2	81	88	PF11976	0.534
LIG_SUMO_SIM_par_1	81	88	PF11976	0.528
LIG_TRAF2_1	291	294	PF00917	0.620
LIG_UBA3_1	82	90	PF00899	0.536
MOD_CK1_1	159	165	PF00069	0.430
MOD_CK1_1	3	9	PF00069	0.671
MOD_CK1_1	320	326	PF00069	0.551
MOD_CK2_1	343	349	PF00069	0.826
MOD_GlcNHglycan	119	122	PF01048	0.335
MOD_GlcNHglycan	92	95	PF01048	0.322
MOD_GSK3_1	198	205	PF00069	0.442
MOD_GSK3_1	28	35	PF00069	0.595
MOD_GSK3_1	3	10	PF00069	0.697
MOD_GSK3_1	85	92	PF00069	0.549
MOD_N-GLC_1	171	176	PF02516	0.616
MOD_N-GLC_1	7	12	PF02516	0.595
MOD_NEK2_1	236	241	PF00069	0.542
MOD_NEK2_1	89	94	PF00069	0.541
MOD_PIKK_1	273	279	PF00454	0.603
MOD_PK_1	28	34	PF00069	0.608
MOD_PK_1	303	309	PF00069	0.521
MOD_PKA_1	111	117	PF00069	0.556
MOD_PKA_2	273	279	PF00069	0.525
MOD_Plk_1	320	326	PF00069	0.538
MOD_Plk_4	202	208	PF00069	0.445
MOD_Plk_4	343	349	PF00069	0.568
MOD_Plk_4	44	50	PF00069	0.644
MOD_ProDKin_1	156	162	PF00069	0.488
MOD_ProDKin_1	171	177	PF00069	0.563
MOD_SUMO_for_1	335	338	PF00179	0.546
TRG_DiLeu_BaEn_1	217	222	PF01217	0.608
TRG_ENDOCYTIC_2	29	32	PF00928	0.624
TRG_ER_diArg_1	190	193	PF00400	0.444
TRG_ER_diArg_1	209	211	PF00400	0.559
TRG_ER_diArg_1	95	97	PF00400	0.514
TRG_NES_CRM1_1	220	235	PF08389	0.590
TRG_NLS_Bipartite_1	192	212	PF00514	0.551
TRG_NLS_MonoExtN_4	298	304	PF00514	0.624

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8G4	Leptomonas seymouri	55%	100%
A0A0N1I914	Leptomonas seymouri	90%	100%
A0A0N1PE41	Leptomonas seymouri	48%	97%
A0A0S4ILS7	Bodo saltans	24%	100%
A0A0S4IME5	Bodo saltans	58%	100%
A0A0S4IQW2	Bodo saltans	44%	78%
A0A0S4IW81	Bodo saltans	74%	97%
A0A1X0NFA8	Trypanosomatidae	49%	92%
A0A1X0P0G5	Trypanosomatidae	77%	92%
A0A1X0P3L9	Trypanosomatidae	57%	100%
A0A3R7KT84	Trypanosoma rangeli	56%	99%
A0A422NFU4	Trypanosoma rangeli	45%	84%
A0A422NKU6	Trypanosoma rangeli	77%	91%
A2VDS0	Bos taurus	31%	97%
A4H5F1	Leishmania braziliensis	50%	100%
A4HLQ5	Leishmania braziliensis	54%	100%
A4HQ54	Leishmania braziliensis	95%	100%
A4HTP6	Leishmania infantum	49%	100%
A4I955	Leishmania infantum	55%	100%
A4IDV3	Leishmania infantum	99%	100%
A5UNK4	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	30%	100%
A6W1C7	Marinomonas sp. (strain MWYL1)	42%	100%
B0R7B4	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	26%	100%
B7IFM5	Thermosipho africanus (strain TCF52B)	42%	100%
B8GZV1	Caulobacter vibrioides (strain NA1000 / CB15N)	44%	100%
B9KPJ0	Cereibacter sphaeroides (strain KD131 / KCTC 12085)	41%	100%
C9ZPE9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	93%
D0A464	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	74%	95%
D0A6B7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	81%
E0Z5R2	Leishmania donovani	55%	100%
E9AMI3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9ATX4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9B430	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
O08618	Rattus norvegicus	32%	97%
O26877	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	28%	100%
O28853	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	26%	100%
O29666	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	29%	100%
O33924	Corynebacterium ammoniagenes	41%	100%
O52958	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	32%	100%
O59586	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	31%	100%
O60256	Homo sapiens	32%	97%
O64888	Arabidopsis thaliana	40%	91%
O67556	Aquifex aeolicus (strain VF5)	42%	100%
O94413	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	100%
P09330	Rattus norvegicus	42%	100%
P0A1V6	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	44%	100%
P0A1V7	Salmonella typhi	44%	100%
P0A717	Escherichia coli (strain K12)	44%	100%
P0A718	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	44%	100%
P0A719	Escherichia coli O157:H7	44%	100%
P0DB98	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	41%	100%
P0DB99	Streptococcus pyogenes serotype M3 (strain SSI-1)	41%	100%
P0DC00	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	32%	100%
P0DC01	Streptococcus pyogenes serotype M3 (strain SSI-1)	32%	100%
P11908	Homo sapiens	42%	100%
P14193	Bacillus subtilis (strain 168)	41%	100%
P21108	Homo sapiens	40%	100%
P38063	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	100%
P38620	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	100%
P38689	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	100%
P42816	Bacillus caldolyticus	44%	100%
P44328	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	44%	100%
P46585	Candida albicans	40%	100%
P47304	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	39%	100%
P56184	Helicobacter pylori (strain ATCC 700392 / 26695)	44%	100%
P57266	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	43%	100%
P59512	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	42%	100%
P60891	Homo sapiens	41%	100%
P60892	Rattus norvegicus	41%	100%
P65233	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	43%	100%
P65234	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	45%	100%
P65235	Neisseria meningitidis serogroup B (strain MC58)	45%	100%
P65236	Staphylococcus aureus (strain Mu50 / ATCC 700699)	42%	100%
P65237	Staphylococcus aureus (strain N315)	42%	100%
P65238	Staphylococcus aureus (strain MW2)	42%	100%
P65239	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	43%	100%
P65240	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	43%	100%
P65241	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	33%	100%
P65242	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	33%	100%
P65243	Streptococcus pyogenes serotype M1	41%	100%
P65245	Streptococcus pyogenes serotype M18 (strain MGAS8232)	41%	100%
P75044	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	40%	100%
P87171	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P9WKE2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	43%	100%
P9WKE3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	43%	100%
Q08DW2	Bos taurus	34%	100%
Q0ARN5	Maricaulis maris (strain MCS10)	42%	100%
Q0BPP0	Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)	41%	100%
Q0C5A1	Hyphomonas neptunium (strain ATCC 15444)	42%	100%
Q14558	Homo sapiens	34%	100%
Q1LTH2	Baumannia cicadellinicola subsp. Homalodisca coagulata	42%	100%
Q27680	Leishmania donovani	49%	96%
Q28DH0	Xenopus tropicalis	31%	100%
Q2HJ58	Bos taurus	41%	100%
Q42581	Arabidopsis thaliana	40%	89%
Q42583	Arabidopsis thaliana	40%	90%
Q48793	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	41%	100%
Q49V09	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	42%	100%
Q4J9A6	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	27%	100%
Q4L3F7	Staphylococcus haemolyticus (strain JCSC1435)	41%	100%
Q4Q0M2	Leishmania major	98%	100%
Q4Q3Z4	Leishmania major	55%	100%
Q4QI56	Leishmania major	49%	100%
Q4R4R7	Macaca fascicularis	42%	100%
Q4R4U3	Macaca fascicularis	41%	100%
Q54PA9	Dictyostelium discoideum	43%	100%
Q54QU9	Dictyostelium discoideum	35%	100%
Q55848	Synechocystis sp. (strain PCC 6803 / Kazusa)	42%	100%
Q58761	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	28%	100%
Q59988	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	42%	100%
Q5HIH5	Staphylococcus aureus (strain COL)	42%	100%
Q5HRQ5	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	41%	100%
Q5R8F8	Pongo abelii	42%	100%
Q5RBA8	Pongo abelii	32%	97%
Q5RFJ7	Pongo abelii	41%	100%
Q5XC85	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	32%	100%
Q5XEL0	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	41%	100%
Q5XGI0	Xenopus tropicalis	42%	100%
Q5ZI49	Gallus gallus	42%	100%
Q5ZL26	Gallus gallus	32%	97%
Q63468	Rattus norvegicus	34%	100%
Q63XL8	Burkholderia pseudomallei (strain K96243)	45%	100%
Q680A5	Arabidopsis thaliana	25%	100%
Q69XQ6	Oryza sativa subsp. japonica	39%	90%
Q6AJL7	Desulfotalea psychrophila (strain LSv54 / DSM 12343)	46%	100%
Q6GBY8	Staphylococcus aureus (strain MSSA476)	42%	100%
Q6GJH1	Staphylococcus aureus (strain MRSA252)	42%	100%
Q6Z2L5	Oryza sativa subsp. japonica	40%	90%
Q6ZFT5	Oryza sativa subsp. japonica	24%	100%
Q723E1	Listeria monocytogenes serotype 4b (strain F2365)	38%	100%
Q724L4	Listeria monocytogenes serotype 4b (strain F2365)	41%	100%
Q72V73	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	42%	100%
Q75JN8	Dictyostelium discoideum	38%	100%
Q7M8J0	Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)	45%	100%
Q7MMZ1	Vibrio vulnificus (strain YJ016)	43%	100%
Q7MT83	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)	41%	100%
Q7N590	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	44%	100%
Q7NM67	Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)	43%	100%
Q7NQS9	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	46%	100%
Q7U7L5	Parasynechococcus marenigrum (strain WH8102)	42%	100%
Q7UPM4	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	41%	100%
Q7V111	Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)	42%	100%
Q7V6S2	Prochlorococcus marinus (strain MIT 9313)	41%	100%
Q7VBH4	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	43%	100%
Q7VFY9	Helicobacter hepaticus (strain ATCC 51449 / 3B1)	46%	100%
Q7VL55	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	44%	100%
Q7VR76	Blochmannia floridanus	42%	100%
Q7VUH1	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	46%	100%
Q7W181	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	47%	100%
Q7WNY4	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	47%	100%
Q7ZXC9	Xenopus laevis	42%	100%
Q81J97	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	41%	100%
Q81VZ0	Bacillus anthracis	41%	100%
Q82HE7	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	43%	100%
Q82TQ4	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	45%	100%
Q82ZA5	Enterococcus faecalis (strain ATCC 700802 / V583)	42%	100%
Q832Z5	Enterococcus faecalis (strain ATCC 700802 / V583)	37%	100%
Q83AQ1	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	42%	100%
Q83TK1	Listeria welshimeri	41%	100%
Q83YI7	Listeria ivanovii	41%	100%
Q87A22	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	43%	100%
Q87RN8	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	44%	100%
Q888C6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	45%	100%
Q88PX6	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	45%	100%
Q88VA5	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	38%	100%
Q88Z84	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	39%	100%
Q899I8	Clostridium tetani (strain Massachusetts / E88)	43%	100%
Q89DJ1	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	43%	100%
Q8CQU7	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	41%	100%
Q8DFF5	Vibrio vulnificus (strain CMCP6)	43%	100%
Q8DU94	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	34%	100%
Q8DWM2	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	40%	100%
Q8DZK4	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	35%	100%
Q8E2H0	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	41%	100%
Q8E568	Streptococcus agalactiae serotype III (strain NEM316)	35%	100%
Q8E7X8	Streptococcus agalactiae serotype III (strain NEM316)	41%	100%
Q8EAQ9	Shewanella oneidensis (strain MR-1)	44%	100%
Q8EU34	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	41%	100%
Q8EZN0	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	42%	100%
Q8FQV2	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	43%	100%
Q8FZF0	Brucella suis biovar 1 (strain 1330)	43%	100%
Q8G5P2	Bifidobacterium longum (strain NCC 2705)	41%	100%
Q8K9X2	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	43%	100%
Q8KCQ2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	42%	100%
Q8NRU9	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	42%	100%
Q8P137	Streptococcus pyogenes serotype M18 (strain MGAS8232)	32%	100%
Q8PC63	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	42%	100%
Q8PNU0	Xanthomonas axonopodis pv. citri (strain 306)	43%	100%
Q8PUX3	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	28%	100%
Q8R574	Mus musculus	32%	97%
Q8R753	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)	47%	100%
Q8RHM2	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	42%	100%
Q8S2E5	Oryza sativa subsp. japonica	23%	88%
Q8TRK8	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	27%	100%
Q8TUT6	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	28%	100%
Q8U458	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	34%	100%
Q8UDA9	Agrobacterium fabrum (strain C58 / ATCC 33970)	43%	100%
Q8XHJ4	Clostridium perfringens (strain 13 / Type A)	44%	100%
Q8Y2E1	Ralstonia solanacearum (strain GMI1000)	48%	100%
Q8Y9L8	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	38%	100%
Q8YIG1	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	43%	100%
Q8YN97	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	41%	100%
Q8ZEY2	Yersinia pestis	43%	100%
Q8ZU24	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	30%	100%
Q92EF1	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	38%	100%
Q92F68	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	42%	100%
Q92N73	Rhizobium meliloti (strain 1021)	44%	100%
Q93Z66	Arabidopsis thaliana	24%	87%
Q973F3	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	28%	100%
Q97CA5	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	28%	100%
Q97E93	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	43%	100%
Q97Z86	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	28%	100%
Q98HW3	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	44%	100%
Q98R83	Mycoplasmopsis pulmonis (strain UAB CTIP)	36%	100%
Q99ZR0	Streptococcus pyogenes serotype M1	32%	100%
Q9AAV6	Caulobacter vibrioides (strain ATCC 19089 / CB15)	44%	100%
Q9CD45	Mycobacterium leprae (strain TN)	44%	100%
Q9CEI4	Lactococcus lactis subsp. lactis (strain IL1403)	35%	100%
Q9CHB8	Lactococcus lactis subsp. lactis (strain IL1403)	43%	100%
Q9CP22	Pasteurella multocida (strain Pm70)	45%	100%
Q9CS42	Mus musculus	42%	100%
Q9D0M1	Mus musculus	34%	100%
Q9D7G0	Mus musculus	41%	100%
Q9EWS0	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	32%	100%
Q9HLV6	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	23%	100%
Q9HN88	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	26%	100%
Q9HVC5	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	46%	100%
Q9K3U0	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	43%	100%
Q9KGJ5	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	42%	100%
Q9KQ22	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	44%	100%
Q9PA76	Xylella fastidiosa (strain 9a5c)	43%	100%
Q9PP15	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	45%	100%
Q9PQV0	Ureaplasma parvum serovar 3 (strain ATCC 700970)	37%	100%
Q9RUD2	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	38%	100%
Q9UY08	Pyrococcus abyssi (strain GE5 / Orsay)	31%	100%
Q9X1W3	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	46%	100%
Q9XG98	Spinacia oleracea	40%	100%
Q9XG99	Spinacia oleracea	41%	91%
Q9XGA0	Spinacia oleracea	24%	88%
Q9XGA1	Spinacia oleracea	27%	100%
Q9YAW0	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	24%	100%
Q9ZLA1	Helicobacter pylori (strain J99 / ATCC 700824)	44%	100%
V5BEF5	Trypanosoma cruzi	49%	89%
V5BQA6	Trypanosoma cruzi	78%	92%
V5DQE3	Trypanosoma cruzi	55%	99%