Ankyrin repeats (3 copies)/Ankyrin repeat, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Ankyrin repeats (3 copies), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IHJ7_LEIDO

TriTrypDb:

LdBPK_330150.1 , LdCL_330006400 , LDHU3_33.0170

Length:

408

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHJ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHJ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	339	343	PF00656	0.559
CLV_C14_Caspase3-7	370	374	PF00656	0.522
CLV_NRD_NRD_1	377	379	PF00675	0.497
CLV_NRD_NRD_1	384	386	PF00675	0.533
CLV_NRD_NRD_1	61	63	PF00675	0.529
CLV_PCSK_KEX2_1	376	378	PF00082	0.502
CLV_PCSK_KEX2_1	384	386	PF00082	0.530
CLV_PCSK_KEX2_1	61	63	PF00082	0.560
CLV_PCSK_SKI1_1	209	213	PF00082	0.429
CLV_PCSK_SKI1_1	21	25	PF00082	0.448
CLV_PCSK_SKI1_1	272	276	PF00082	0.498
DOC_ANK_TNKS_1	236	243	PF00023	0.468
DOC_CYCLIN_yCln2_LP_2	193	199	PF00134	0.407
DOC_MAPK_MEF2A_6	225	233	PF00069	0.402
DOC_PP2B_LxvP_1	193	196	PF13499	0.454
DOC_USP7_MATH_1	334	338	PF00917	0.553
DOC_USP7_MATH_1	364	368	PF00917	0.543
DOC_WW_Pin1_4	128	133	PF00397	0.300
DOC_WW_Pin1_4	398	403	PF00397	0.582
DOC_WW_Pin1_4	45	50	PF00397	0.517
LIG_14-3-3_CanoR_1	176	180	PF00244	0.517
LIG_14-3-3_CanoR_1	207	215	PF00244	0.511
LIG_14-3-3_CanoR_1	237	241	PF00244	0.401
LIG_14-3-3_CanoR_1	272	277	PF00244	0.396
LIG_14-3-3_CanoR_1	306	316	PF00244	0.479
LIG_14-3-3_CanoR_1	376	382	PF00244	0.529
LIG_14-3-3_CanoR_1	384	388	PF00244	0.426
LIG_14-3-3_CanoR_1	55	61	PF00244	0.562
LIG_14-3-3_CterR_2	404	408	PF00244	0.685
LIG_APCC_ABBA_1	195	200	PF00400	0.479
LIG_BIR_II_1	1	5	PF00653	0.636
LIG_BIR_III_3	1	5	PF00653	0.609
LIG_BIR_III_4	92	96	PF00653	0.399
LIG_BRCT_BRCA1_1	103	107	PF00533	0.319
LIG_BRCT_BRCA1_1	246	250	PF00533	0.536
LIG_EH_1	42	46	PF12763	0.528
LIG_FHA_1	176	182	PF00498	0.360
LIG_FHA_1	27	33	PF00498	0.440
LIG_FHA_1	292	298	PF00498	0.524
LIG_FHA_1	308	314	PF00498	0.456
LIG_FHA_1	82	88	PF00498	0.457
LIG_FHA_2	208	214	PF00498	0.523
LIG_FHA_2	218	224	PF00498	0.604
LIG_FHA_2	300	306	PF00498	0.456
LIG_Integrin_RGD_1	340	342	PF01839	0.570
LIG_Integrin_RGD_1	40	42	PF01839	0.524
LIG_LIR_Apic_2	159	163	PF02991	0.445
LIG_LIR_Gen_1	104	115	PF02991	0.319
LIG_LIR_Gen_1	22	32	PF02991	0.383
LIG_LIR_Gen_1	254	264	PF02991	0.496
LIG_LIR_Nem_3	22	27	PF02991	0.385
LIG_LIR_Nem_3	254	260	PF02991	0.499
LIG_LIR_Nem_3	386	391	PF02991	0.483
LIG_NRBOX	226	232	PF00104	0.419
LIG_PCNA_PIPBox_1	273	282	PF02747	0.392
LIG_PCNA_yPIPBox_3	17	27	PF02747	0.558
LIG_PCNA_yPIPBox_3	185	194	PF02747	0.428
LIG_PCNA_yPIPBox_3	272	280	PF02747	0.353
LIG_SH2_CRK	16	20	PF00017	0.633
LIG_SH2_CRK	160	164	PF00017	0.520
LIG_SH2_STAT5	160	163	PF00017	0.689
LIG_SH2_STAT5	290	293	PF00017	0.465
LIG_SH2_STAT5	358	361	PF00017	0.501
LIG_SH2_STAT5	73	76	PF00017	0.635
LIG_SH3_3	152	158	PF00018	0.461
LIG_SH3_3	2	8	PF00018	0.652
LIG_SUMO_SIM_anti_2	226	232	PF11976	0.450
LIG_SUMO_SIM_anti_2	34	40	PF11976	0.439
LIG_SUMO_SIM_par_1	228	235	PF11976	0.401
LIG_SUMO_SIM_par_1	244	249	PF11976	0.388
MOD_CDC14_SPxK_1	401	404	PF00782	0.655
MOD_CDK_SPxK_1	398	404	PF00069	0.623
MOD_CK1_1	128	134	PF00069	0.369
MOD_CK1_1	299	305	PF00069	0.562
MOD_CK1_1	94	100	PF00069	0.437
MOD_CK2_1	207	213	PF00069	0.521
MOD_CK2_1	299	305	PF00069	0.429
MOD_CK2_1	341	347	PF00069	0.571
MOD_CK2_1	364	370	PF00069	0.600
MOD_GlcNHglycan	127	130	PF01048	0.369
MOD_GlcNHglycan	143	146	PF01048	0.171
MOD_GlcNHglycan	165	168	PF01048	0.533
MOD_GlcNHglycan	92	96	PF01048	0.399
MOD_GSK3_1	101	108	PF00069	0.366
MOD_GSK3_1	263	270	PF00069	0.513
MOD_GSK3_1	292	299	PF00069	0.504
MOD_LATS_1	375	381	PF00433	0.488
MOD_N-GLC_1	125	130	PF02516	0.418
MOD_NEK2_1	105	110	PF00069	0.369
MOD_NEK2_1	201	206	PF00069	0.401
MOD_NEK2_2	175	180	PF00069	0.424
MOD_NEK2_2	56	61	PF00069	0.512
MOD_PKA_1	376	382	PF00069	0.529
MOD_PKA_2	175	181	PF00069	0.521
MOD_PKA_2	236	242	PF00069	0.513
MOD_PKA_2	376	382	PF00069	0.530
MOD_PKA_2	383	389	PF00069	0.441
MOD_PKB_1	89	97	PF00069	0.346
MOD_Plk_1	291	297	PF00069	0.505
MOD_Plk_4	175	181	PF00069	0.417
MOD_Plk_4	225	231	PF00069	0.426
MOD_Plk_4	236	242	PF00069	0.509
MOD_Plk_4	263	269	PF00069	0.477
MOD_Plk_4	292	298	PF00069	0.563
MOD_Plk_4	299	305	PF00069	0.415
MOD_Plk_4	31	37	PF00069	0.461
MOD_Plk_4	377	383	PF00069	0.618
MOD_ProDKin_1	128	134	PF00069	0.300
MOD_ProDKin_1	398	404	PF00069	0.593
MOD_ProDKin_1	45	51	PF00069	0.510
MOD_SUMO_rev_2	353	357	PF00179	0.473
TRG_DiLeu_BaEn_1	347	352	PF01217	0.473
TRG_DiLeu_BaLyEn_6	143	148	PF01217	0.346
TRG_ENDOCYTIC_2	198	201	PF00928	0.447
TRG_ER_diArg_1	376	378	PF00400	0.471
TRG_ER_diArg_1	60	62	PF00400	0.520
TRG_ER_diArg_1	88	91	PF00400	0.346
TRG_Pf-PMV_PEXEL_1	146	150	PF00026	0.395
TRG_Pf-PMV_PEXEL_1	21	25	PF00026	0.448
TRG_Pf-PMV_PEXEL_1	317	321	PF00026	0.396
TRG_Pf-PMV_PEXEL_1	349	353	PF00026	0.461

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBF8	Leptomonas seymouri	52%	100%
A0A0S4JPA5	Bodo saltans	28%	100%
A4HL51	Leishmania braziliensis	75%	100%
A4I8N0	Leishmania infantum	100%	100%
E9B3J2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q4K9	Leishmania major	93%	100%