OTT_1508-like_deaminase_putative/Pfam:PF14441

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

OTT_1508-like deaminase, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IHJ6_LEIDO

TriTrypDb:

LdBPK_331860.1 , LdCL_330025400 , LDHU3_33.2750

Length:

271

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHJ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHJ6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	37	43	PF00089	0.684
CLV_NRD_NRD_1	119	121	PF00675	0.503
CLV_NRD_NRD_1	267	269	PF00675	0.648
CLV_PCSK_KEX2_1	119	121	PF00082	0.503
CLV_PCSK_KEX2_1	267	269	PF00082	0.733
CLV_PCSK_SKI1_1	166	170	PF00082	0.502
CLV_PCSK_SKI1_1	267	271	PF00082	0.624
DOC_CYCLIN_RxL_1	160	170	PF00134	0.518
DOC_PP2B_LxvP_1	261	264	PF13499	0.704
DOC_PP4_FxxP_1	251	254	PF00568	0.535
DOC_USP7_MATH_1	103	107	PF00917	0.567
DOC_USP7_MATH_1	210	214	PF00917	0.529
DOC_USP7_MATH_1	238	242	PF00917	0.574
DOC_WW_Pin1_4	250	255	PF00397	0.654
DOC_WW_Pin1_4	47	52	PF00397	0.678
LIG_BRCT_BRCA1_1	48	52	PF00533	0.771
LIG_deltaCOP1_diTrp_1	141	148	PF00928	0.683
LIG_FHA_1	172	178	PF00498	0.511
LIG_FHA_1	24	30	PF00498	0.725
LIG_FHA_1	242	248	PF00498	0.662
LIG_FHA_1	9	15	PF00498	0.658
LIG_FHA_2	123	129	PF00498	0.511
LIG_LIR_Gen_1	152	159	PF02991	0.473
LIG_LIR_Nem_3	152	156	PF02991	0.475
LIG_NRP_CendR_1	268	271	PF00754	0.662
LIG_Pex14_2	207	211	PF04695	0.607
LIG_SH2_CRK	38	42	PF00017	0.798
LIG_SH2_NCK_1	6	10	PF00017	0.759
LIG_SH2_STAT5	122	125	PF00017	0.472
LIG_SH2_STAT5	225	228	PF00017	0.588
LIG_SH2_STAT5	57	60	PF00017	0.577
LIG_SH2_STAT5	72	75	PF00017	0.547
LIG_SH3_3	180	186	PF00018	0.596
LIG_SH3_3	213	219	PF00018	0.501
LIG_SH3_3	38	44	PF00018	0.717
LIG_SUMO_SIM_anti_2	212	218	PF11976	0.496
LIG_SUMO_SIM_par_1	93	100	PF11976	0.603
LIG_UBA3_1	168	173	PF00899	0.458
MOD_CK1_1	106	112	PF00069	0.639
MOD_CK1_1	241	247	PF00069	0.611
MOD_CK2_1	122	128	PF00069	0.488
MOD_CK2_1	250	256	PF00069	0.603
MOD_GlcNHglycan	114	117	PF01048	0.619
MOD_GlcNHglycan	240	243	PF01048	0.690
MOD_GSK3_1	103	110	PF00069	0.612
MOD_GSK3_1	122	129	PF00069	0.587
MOD_GSK3_1	171	178	PF00069	0.508
MOD_GSK3_1	20	27	PF00069	0.668
MOD_N-GLC_1	126	131	PF02516	0.531
MOD_NEK2_1	224	229	PF00069	0.520
MOD_NEK2_1	29	34	PF00069	0.660
MOD_NEK2_1	8	13	PF00069	0.679
MOD_NEK2_2	75	80	PF00069	0.681
MOD_PIKK_1	128	134	PF00454	0.582
MOD_PIKK_1	171	177	PF00454	0.549
MOD_Plk_1	126	132	PF00069	0.531
MOD_ProDKin_1	250	256	PF00069	0.653
MOD_ProDKin_1	47	53	PF00069	0.674
MOD_SUMO_rev_2	159	169	PF00179	0.477
MOD_SUMO_rev_2	27	32	PF00179	0.684
TRG_DiLeu_BaEn_1	256	261	PF01217	0.640
TRG_ENDOCYTIC_2	38	41	PF00928	0.804
TRG_ER_diArg_1	118	120	PF00400	0.534
TRG_ER_diArg_1	267	269	PF00400	0.683
TRG_Pf-PMV_PEXEL_1	166	170	PF00026	0.502

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P844	Leptomonas seymouri	61%	71%
A4HLN6	Leishmania braziliensis	79%	96%
A4I972	Leishmania infantum	100%	100%
E9B413	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4Q411	Leishmania major	96%	100%