Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IHI7_LEIDO

TriTrypDb:

LdCL_110016700

Length:

238

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHI7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHI7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	191	195	PF00656	0.501
CLV_NRD_NRD_1	20	22	PF00675	0.700
CLV_PCSK_KEX2_1	19	21	PF00082	0.702
CLV_PCSK_SKI1_1	21	25	PF00082	0.748
DEG_APCC_DBOX_1	31	39	PF00400	0.571
DEG_SCF_FBW7_1	96	103	PF00400	0.518
DOC_MAPK_gen_1	19	28	PF00069	0.695
DOC_MAPK_MEF2A_6	150	158	PF00069	0.597
DOC_USP7_MATH_1	109	113	PF00917	0.671
DOC_USP7_MATH_1	87	91	PF00917	0.646
DOC_USP7_UBL2_3	85	89	PF12436	0.653
DOC_WW_Pin1_4	150	155	PF00397	0.675
DOC_WW_Pin1_4	214	219	PF00397	0.525
DOC_WW_Pin1_4	96	101	PF00397	0.657
LIG_14-3-3_CanoR_1	102	106	PF00244	0.653
LIG_14-3-3_CanoR_1	222	226	PF00244	0.640
LIG_14-3-3_CanoR_1	41	47	PF00244	0.641
LIG_14-3-3_CanoR_1	95	99	PF00244	0.637
LIG_BIR_II_1	1	5	PF00653	0.685
LIG_FHA_1	102	108	PF00498	0.714
LIG_FHA_1	151	157	PF00498	0.722
LIG_FHA_1	204	210	PF00498	0.710
LIG_FHA_1	22	28	PF00498	0.660
LIG_FHA_1	43	49	PF00498	0.684
LIG_FHA_2	189	195	PF00498	0.503
LIG_FHA_2	72	78	PF00498	0.706
LIG_Integrin_RGD_1	32	34	PF01839	0.533
LIG_LIR_Nem_3	97	101	PF02991	0.618
LIG_SH2_CRK	98	102	PF00017	0.657
LIG_SH2_STAT5	98	101	PF00017	0.559
LIG_SH3_3	142	148	PF00018	0.708
LIG_SUMO_SIM_par_1	205	211	PF11976	0.609
LIG_TRAF2_1	111	114	PF00917	0.661
LIG_TRAF2_1	126	129	PF00917	0.537
LIG_TRAF2_1	164	167	PF00917	0.690
LIG_TRAF2_1	59	62	PF00917	0.610
LIG_TYR_ITIM	96	101	PF00017	0.657
MOD_CDK_SPxK_1	96	102	PF00069	0.658
MOD_CDK_SPxxK_3	150	157	PF00069	0.653
MOD_CK1_1	140	146	PF00069	0.697
MOD_CK1_1	224	230	PF00069	0.637
MOD_CK1_1	90	96	PF00069	0.658
MOD_CK2_1	1	7	PF00069	0.643
MOD_CK2_1	109	115	PF00069	0.667
MOD_CK2_1	140	146	PF00069	0.697
MOD_CK2_1	71	77	PF00069	0.704
MOD_GlcNHglycan	139	142	PF01048	0.688
MOD_GlcNHglycan	194	197	PF01048	0.618
MOD_GlcNHglycan	226	230	PF01048	0.642
MOD_GlcNHglycan	68	71	PF01048	0.754
MOD_GlcNHglycan	88	92	PF01048	0.650
MOD_GSK3_1	146	153	PF00069	0.786
MOD_GSK3_1	188	195	PF00069	0.573
MOD_GSK3_1	221	228	PF00069	0.713
MOD_GSK3_1	90	97	PF00069	0.640
MOD_NEK2_1	1	6	PF00069	0.682
MOD_NEK2_1	137	142	PF00069	0.688
MOD_NEK2_1	225	230	PF00069	0.638
MOD_PIKK_1	208	214	PF00454	0.614
MOD_PIKK_1	231	237	PF00454	0.632
MOD_PKA_2	101	107	PF00069	0.656
MOD_PKA_2	221	227	PF00069	0.662
MOD_PKA_2	94	100	PF00069	0.635
MOD_PKB_1	19	27	PF00069	0.611
MOD_Plk_2-3	221	227	PF00069	0.638
MOD_Plk_4	34	40	PF00069	0.530
MOD_ProDKin_1	150	156	PF00069	0.677
MOD_ProDKin_1	214	220	PF00069	0.524
MOD_ProDKin_1	96	102	PF00069	0.658
MOD_SUMO_rev_2	123	132	PF00179	0.668
TRG_DiLeu_BaEn_1	181	186	PF01217	0.519
TRG_ENDOCYTIC_2	98	101	PF00928	0.668
TRG_ER_diArg_1	19	21	PF00400	0.722

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9ANQ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4QGX3	Leishmania major	85%	100%