Proteophosphoglycan ppg4

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IHG2_LEIDO

TriTrypDb:

LdBPK_341580.1 , LdCL_340022100 , LDHU3_34.2410

Length:

1001

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHG2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHG2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	232	236	PF00656	0.527
CLV_C14_Caspase3-7	390	394	PF00656	0.596
CLV_C14_Caspase3-7	490	494	PF00656	0.632
CLV_C14_Caspase3-7	767	771	PF00656	0.679
CLV_C14_Caspase3-7	805	809	PF00656	0.562
CLV_C14_Caspase3-7	984	988	PF00656	0.611
CLV_NRD_NRD_1	179	181	PF00675	0.527
CLV_NRD_NRD_1	303	305	PF00675	0.694
CLV_NRD_NRD_1	441	443	PF00675	0.597
CLV_NRD_NRD_1	471	473	PF00675	0.614
CLV_NRD_NRD_1	523	525	PF00675	0.642
CLV_NRD_NRD_1	563	565	PF00675	0.624
CLV_NRD_NRD_1	643	645	PF00675	0.696
CLV_NRD_NRD_1	668	670	PF00675	0.596
CLV_NRD_NRD_1	68	70	PF00675	0.651
CLV_NRD_NRD_1	822	824	PF00675	0.576
CLV_NRD_NRD_1	833	835	PF00675	0.560
CLV_NRD_NRD_1	847	849	PF00675	0.670
CLV_NRD_NRD_1	9	11	PF00675	0.660
CLV_NRD_NRD_1	974	976	PF00675	0.572
CLV_PCSK_FUR_1	820	824	PF00082	0.576
CLV_PCSK_FUR_1	972	976	PF00082	0.573
CLV_PCSK_KEX2_1	179	181	PF00082	0.527
CLV_PCSK_KEX2_1	303	305	PF00082	0.716
CLV_PCSK_KEX2_1	441	443	PF00082	0.597
CLV_PCSK_KEX2_1	471	473	PF00082	0.614
CLV_PCSK_KEX2_1	523	525	PF00082	0.642
CLV_PCSK_KEX2_1	563	565	PF00082	0.641
CLV_PCSK_KEX2_1	575	577	PF00082	0.621
CLV_PCSK_KEX2_1	615	617	PF00082	0.569
CLV_PCSK_KEX2_1	642	644	PF00082	0.698
CLV_PCSK_KEX2_1	822	824	PF00082	0.581
CLV_PCSK_KEX2_1	847	849	PF00082	0.682
CLV_PCSK_KEX2_1	972	974	PF00082	0.578
CLV_PCSK_PC1ET2_1	575	577	PF00082	0.671
CLV_PCSK_PC1ET2_1	615	617	PF00082	0.569
CLV_PCSK_SKI1_1	304	308	PF00082	0.587
CLV_PCSK_SKI1_1	399	403	PF00082	0.645
CLV_PCSK_SKI1_1	548	552	PF00082	0.607
CLV_PCSK_SKI1_1	702	706	PF00082	0.616
CLV_PCSK_SKI1_1	81	85	PF00082	0.653
CLV_PCSK_SKI1_1	823	827	PF00082	0.554
CLV_PCSK_SKI1_1	996	1000	PF00082	0.582
DEG_APCC_DBOX_1	547	555	PF00400	0.617
DEG_APCC_DBOX_1	656	664	PF00400	0.615
DEG_APCC_DBOX_1	697	705	PF00400	0.616
DEG_APCC_DBOX_1	972	980	PF00400	0.531
DEG_COP1_1	235	243	PF00400	0.598
DEG_Kelch_actinfilin_1	12	16	PF01344	0.637
DEG_SPOP_SBC_1	251	255	PF00917	0.608
DOC_CYCLIN_RxL_1	367	381	PF00134	0.679
DOC_MAPK_gen_1	10	17	PF00069	0.669
DOC_MAPK_MEF2A_6	10	17	PF00069	0.636
DOC_PP1_RVXF_1	277	283	PF00149	0.644
DOC_PP1_RVXF_1	371	378	PF00149	0.682
DOC_USP7_MATH_1	145	149	PF00917	0.642
DOC_USP7_MATH_1	156	160	PF00917	0.656
DOC_USP7_MATH_1	183	187	PF00917	0.624
DOC_USP7_MATH_1	252	256	PF00917	0.659
DOC_USP7_MATH_1	265	269	PF00917	0.601
DOC_USP7_MATH_1	314	318	PF00917	0.621
DOC_USP7_MATH_1	320	324	PF00917	0.609
DOC_USP7_MATH_1	412	416	PF00917	0.635
DOC_USP7_MATH_1	437	441	PF00917	0.675
DOC_USP7_MATH_1	495	499	PF00917	0.552
DOC_USP7_MATH_1	538	542	PF00917	0.667
DOC_USP7_MATH_1	556	560	PF00917	0.498
DOC_USP7_MATH_1	611	615	PF00917	0.558
DOC_USP7_MATH_1	759	763	PF00917	0.670
DOC_USP7_MATH_1	87	91	PF00917	0.603
DOC_USP7_MATH_1	870	874	PF00917	0.589
DOC_WW_Pin1_4	109	114	PF00397	0.540
DOC_WW_Pin1_4	115	120	PF00397	0.588
DOC_WW_Pin1_4	128	133	PF00397	0.506
DOC_WW_Pin1_4	162	167	PF00397	0.708
DOC_WW_Pin1_4	221	226	PF00397	0.639
DOC_WW_Pin1_4	234	239	PF00397	0.598
DOC_WW_Pin1_4	283	288	PF00397	0.671
DOC_WW_Pin1_4	295	300	PF00397	0.585
DOC_WW_Pin1_4	306	311	PF00397	0.594
DOC_WW_Pin1_4	331	336	PF00397	0.661
DOC_WW_Pin1_4	36	41	PF00397	0.643
DOC_WW_Pin1_4	4	9	PF00397	0.650
DOC_WW_Pin1_4	428	433	PF00397	0.646
DOC_WW_Pin1_4	446	451	PF00397	0.566
DOC_WW_Pin1_4	493	498	PF00397	0.633
DOC_WW_Pin1_4	50	55	PF00397	0.573
DOC_WW_Pin1_4	637	642	PF00397	0.594
DOC_WW_Pin1_4	679	684	PF00397	0.651
DOC_WW_Pin1_4	908	913	PF00397	0.756
DOC_WW_Pin1_4	91	96	PF00397	0.686
DOC_WW_Pin1_4	940	945	PF00397	0.767
LIG_14-3-3_CanoR_1	271	276	PF00244	0.686
LIG_14-3-3_CanoR_1	279	287	PF00244	0.613
LIG_14-3-3_CanoR_1	303	307	PF00244	0.591
LIG_14-3-3_CanoR_1	616	621	PF00244	0.673
LIG_14-3-3_CanoR_1	625	633	PF00244	0.635
LIG_14-3-3_CanoR_1	636	641	PF00244	0.536
LIG_14-3-3_CanoR_1	643	649	PF00244	0.616
LIG_14-3-3_CanoR_1	657	661	PF00244	0.494
LIG_14-3-3_CanoR_1	69	73	PF00244	0.649
LIG_14-3-3_CanoR_1	822	831	PF00244	0.652
LIG_14-3-3_CanoR_1	848	858	PF00244	0.687
LIG_14-3-3_CanoR_1	869	879	PF00244	0.666
LIG_14-3-3_CanoR_1	951	956	PF00244	0.573
LIG_14-3-3_CanoR_1	980	989	PF00244	0.551
LIG_BIR_III_2	587	591	PF00653	0.639
LIG_BRCT_BRCA1_1	173	177	PF00533	0.697
LIG_BRCT_BRCA1_1	258	262	PF00533	0.697
LIG_BRCT_BRCA1_1	361	365	PF00533	0.623
LIG_BRCT_BRCA1_1	681	685	PF00533	0.661
LIG_BRCT_BRCA1_2	258	264	PF00533	0.693
LIG_Clathr_ClatBox_1	660	664	PF01394	0.607
LIG_Clathr_ClatBox_1	965	969	PF01394	0.536
LIG_DCNL_PONY_1	1	4	PF03556	0.661
LIG_FHA_1	603	609	PF00498	0.613
LIG_FHA_1	78	84	PF00498	0.650
LIG_FHA_1	857	863	PF00498	0.782
LIG_FHA_1	874	880	PF00498	0.624
LIG_FHA_1	921	927	PF00498	0.671
LIG_FHA_1	943	949	PF00498	0.621
LIG_FHA_1	98	104	PF00498	0.547
LIG_FHA_1	988	994	PF00498	0.454
LIG_FHA_2	193	199	PF00498	0.641
LIG_FHA_2	30	36	PF00498	0.634
LIG_FHA_2	379	385	PF00498	0.634
LIG_FHA_2	472	478	PF00498	0.573
LIG_FHA_2	488	494	PF00498	0.583
LIG_FHA_2	723	729	PF00498	0.636
LIG_FHA_2	881	887	PF00498	0.579
LIG_FHA_2	941	947	PF00498	0.745
LIG_FHA_2	951	957	PF00498	0.675
LIG_LIR_Apic_2	431	436	PF02991	0.608
LIG_LIR_Gen_1	31	41	PF02991	0.660
LIG_LIR_Nem_3	31	36	PF02991	0.662
LIG_LIR_Nem_3	474	479	PF02991	0.547
LIG_LIR_Nem_3	64	68	PF02991	0.621
LIG_LIR_Nem_3	992	998	PF02991	0.502
LIG_PALB2_WD40_1	471	479	PF16756	0.597
LIG_RPA_C_Fungi	664	676	PF08784	0.551
LIG_RPA_C_Fungi	806	818	PF08784	0.557
LIG_SH2_NCK_1	813	817	PF00017	0.580
LIG_SH2_PTP2	433	436	PF00017	0.556
LIG_SH2_SRC	813	816	PF00017	0.581
LIG_SH2_STAP1	577	581	PF00017	0.636
LIG_SH2_STAP1	813	817	PF00017	0.580
LIG_SH2_STAT3	577	580	PF00017	0.679
LIG_SH2_STAT5	391	394	PF00017	0.674
LIG_SH2_STAT5	433	436	PF00017	0.574
LIG_SH2_STAT5	509	512	PF00017	0.527
LIG_SH2_STAT5	632	635	PF00017	0.707
LIG_SH3_1	160	166	PF00018	0.644
LIG_SH3_3	110	116	PF00018	0.683
LIG_SH3_3	131	137	PF00018	0.604
LIG_SH3_3	160	166	PF00018	0.644
LIG_SH3_3	235	241	PF00018	0.640
LIG_SH3_3	284	290	PF00018	0.690
LIG_SH3_3	431	437	PF00018	0.629
LIG_SH3_3	444	450	PF00018	0.554
LIG_SH3_3	455	461	PF00018	0.555
LIG_SH3_3	481	487	PF00018	0.617
LIG_SH3_3	505	511	PF00018	0.625
LIG_SH3_3	514	520	PF00018	0.590
LIG_SH3_3	531	537	PF00018	0.539
LIG_SH3_3	677	683	PF00018	0.580
LIG_SH3_3	777	783	PF00018	0.636
LIG_SH3_3	790	796	PF00018	0.548
LIG_SH3_3	862	868	PF00018	0.636
LIG_SH3_4	835	842	PF00018	0.658
LIG_SUMO_SIM_par_1	12	19	PF11976	0.669
LIG_SUMO_SIM_par_1	962	970	PF11976	0.484
LIG_TRAF2_1	381	384	PF00917	0.611
LIG_TRAF2_1	765	768	PF00917	0.551
LIG_UBA3_1	660	667	PF00899	0.544
LIG_WRPW_2	995	998	PF00400	0.549
LIG_WW_2	793	796	PF00397	0.537
LIG_WW_3	589	593	PF00397	0.681
LIG_WW_3	866	870	PF00397	0.631
MOD_CDC14_SPxK_1	133	136	PF00782	0.618
MOD_CDC14_SPxK_1	298	301	PF00782	0.648
MOD_CDC14_SPxK_1	640	643	PF00782	0.592
MOD_CDK_SPK_2	223	228	PF00069	0.594
MOD_CDK_SPK_2	637	642	PF00069	0.585
MOD_CDK_SPxK_1	130	136	PF00069	0.607
MOD_CDK_SPxK_1	295	301	PF00069	0.652
MOD_CDK_SPxK_1	4	10	PF00069	0.652
MOD_CDK_SPxK_1	637	643	PF00069	0.587
MOD_CDK_SPxxK_3	221	228	PF00069	0.628
MOD_CDK_SPxxK_3	4	11	PF00069	0.654
MOD_CDK_SPxxK_3	637	644	PF00069	0.589
MOD_CK1_1	104	110	PF00069	0.660
MOD_CK1_1	130	136	PF00069	0.668
MOD_CK1_1	167	173	PF00069	0.709
MOD_CK1_1	250	256	PF00069	0.702
MOD_CK1_1	283	289	PF00069	0.671
MOD_CK1_1	309	315	PF00069	0.659
MOD_CK1_1	31	37	PF00069	0.637
MOD_CK1_1	405	411	PF00069	0.568
MOD_CK1_1	423	429	PF00069	0.569
MOD_CK1_1	462	468	PF00069	0.622
MOD_CK1_1	47	53	PF00069	0.586
MOD_CK1_1	55	61	PF00069	0.657
MOD_CK1_1	579	585	PF00069	0.585
MOD_CK1_1	626	632	PF00069	0.681
MOD_CK1_1	762	768	PF00069	0.737
MOD_CK1_1	873	879	PF00069	0.799
MOD_CK1_1	880	886	PF00069	0.658
MOD_CK1_1	890	896	PF00069	0.635
MOD_CK2_1	103	109	PF00069	0.650
MOD_CK2_1	183	189	PF00069	0.608
MOD_CK2_1	29	35	PF00069	0.668
MOD_CK2_1	378	384	PF00069	0.634
MOD_CK2_1	722	728	PF00069	0.654
MOD_CK2_1	761	767	PF00069	0.663
MOD_CK2_1	950	956	PF00069	0.715
MOD_Cter_Amidation	970	973	PF01082	0.443
MOD_GlcNHglycan	103	106	PF01048	0.617
MOD_GlcNHglycan	154	157	PF01048	0.680
MOD_GlcNHglycan	214	218	PF01048	0.677
MOD_GlcNHglycan	231	234	PF01048	0.532
MOD_GlcNHglycan	249	252	PF01048	0.653
MOD_GlcNHglycan	283	286	PF01048	0.652
MOD_GlcNHglycan	322	325	PF01048	0.587
MOD_GlcNHglycan	343	346	PF01048	0.769
MOD_GlcNHglycan	361	364	PF01048	0.634
MOD_GlcNHglycan	404	407	PF01048	0.633
MOD_GlcNHglycan	422	425	PF01048	0.538
MOD_GlcNHglycan	443	446	PF01048	0.582
MOD_GlcNHglycan	484	487	PF01048	0.569
MOD_GlcNHglycan	493	496	PF01048	0.536
MOD_GlcNHglycan	50	53	PF01048	0.686
MOD_GlcNHglycan	505	508	PF01048	0.577
MOD_GlcNHglycan	540	543	PF01048	0.650
MOD_GlcNHglycan	558	561	PF01048	0.489
MOD_GlcNHglycan	567	570	PF01048	0.569
MOD_GlcNHglycan	57	60	PF01048	0.651
MOD_GlcNHglycan	625	628	PF01048	0.638
MOD_GlcNHglycan	646	649	PF01048	0.668
MOD_GlcNHglycan	692	695	PF01048	0.634
MOD_GlcNHglycan	737	740	PF01048	0.620
MOD_GlcNHglycan	85	88	PF01048	0.615
MOD_GlcNHglycan	872	875	PF01048	0.612
MOD_GlcNHglycan	97	100	PF01048	0.632
MOD_GSK3_1	103	110	PF00069	0.558
MOD_GSK3_1	152	159	PF00069	0.683
MOD_GSK3_1	162	169	PF00069	0.639
MOD_GSK3_1	219	226	PF00069	0.645
MOD_GSK3_1	246	253	PF00069	0.703
MOD_GSK3_1	25	32	PF00069	0.658
MOD_GSK3_1	302	309	PF00069	0.620
MOD_GSK3_1	343	350	PF00069	0.621
MOD_GSK3_1	437	444	PF00069	0.695
MOD_GSK3_1	44	51	PF00069	0.607
MOD_GSK3_1	459	466	PF00069	0.656
MOD_GSK3_1	487	494	PF00069	0.632
MOD_GSK3_1	565	572	PF00069	0.637
MOD_GSK3_1	611	618	PF00069	0.566
MOD_GSK3_1	68	75	PF00069	0.670
MOD_GSK3_1	759	766	PF00069	0.662
MOD_GSK3_1	83	90	PF00069	0.575
MOD_GSK3_1	873	880	PF00069	0.712
MOD_GSK3_1	91	98	PF00069	0.602
MOD_GSK3_1	938	945	PF00069	0.636
MOD_GSK3_1	947	954	PF00069	0.556
MOD_GSK3_1	981	988	PF00069	0.508
MOD_N-GLC_1	314	319	PF02516	0.587
MOD_N-GLC_1	538	543	PF02516	0.622
MOD_N-GLC_1	593	598	PF02516	0.687
MOD_NEK2_1	103	108	PF00069	0.672
MOD_NEK2_1	168	173	PF00069	0.699
MOD_NEK2_1	212	217	PF00069	0.624
MOD_NEK2_1	336	341	PF00069	0.722
MOD_NEK2_1	347	352	PF00069	0.563
MOD_NEK2_1	503	508	PF00069	0.644
MOD_NEK2_1	663	668	PF00069	0.545
MOD_NEK2_1	704	709	PF00069	0.624
MOD_NEK2_1	72	77	PF00069	0.680
MOD_NEK2_1	784	789	PF00069	0.667
MOD_NEK2_1	939	944	PF00069	0.631
MOD_NEK2_2	302	307	PF00069	0.589
MOD_NEK2_2	343	348	PF00069	0.606
MOD_PIKK_1	135	141	PF00454	0.652
MOD_PIKK_1	265	271	PF00454	0.673
MOD_PIKK_1	309	315	PF00454	0.661
MOD_PIKK_1	379	385	PF00454	0.635
MOD_PIKK_1	405	411	PF00454	0.590
MOD_PIKK_1	576	582	PF00454	0.678
MOD_PIKK_1	722	728	PF00454	0.680
MOD_PIKK_1	823	829	PF00454	0.589
MOD_PIKK_1	880	886	PF00454	0.640
MOD_PIKK_1	97	103	PF00454	0.645
MOD_PK_1	271	277	PF00069	0.635
MOD_PK_1	543	549	PF00069	0.576
MOD_PK_1	616	622	PF00069	0.628
MOD_PKA_1	441	447	PF00069	0.596
MOD_PKA_1	471	477	PF00069	0.563
MOD_PKA_1	543	549	PF00069	0.576
MOD_PKA_1	615	621	PF00069	0.571
MOD_PKA_1	642	648	PF00069	0.642
MOD_PKA_2	107	113	PF00069	0.709
MOD_PKA_2	127	133	PF00069	0.489
MOD_PKA_2	135	141	PF00069	0.670
MOD_PKA_2	145	151	PF00069	0.585
MOD_PKA_2	171	177	PF00069	0.634
MOD_PKA_2	212	218	PF00069	0.657
MOD_PKA_2	302	308	PF00069	0.631
MOD_PKA_2	357	363	PF00069	0.633
MOD_PKA_2	441	447	PF00069	0.651
MOD_PKA_2	471	477	PF00069	0.574
MOD_PKA_2	487	493	PF00069	0.581
MOD_PKA_2	615	621	PF00069	0.638
MOD_PKA_2	642	648	PF00069	0.703
MOD_PKA_2	656	662	PF00069	0.508
MOD_PKA_2	68	74	PF00069	0.678
MOD_PKA_2	877	883	PF00069	0.632
MOD_PKA_2	950	956	PF00069	0.581
MOD_PKA_2	985	991	PF00069	0.607
MOD_PKB_1	271	279	PF00069	0.644
MOD_PKB_1	642	650	PF00069	0.595
MOD_Plk_1	265	271	PF00069	0.599
MOD_Plk_1	466	472	PF00069	0.558
MOD_Plk_1	759	765	PF00069	0.658
MOD_Plk_4	343	349	PF00069	0.734
MOD_Plk_4	471	477	PF00069	0.563
MOD_Plk_4	656	662	PF00069	0.622
MOD_ProDKin_1	109	115	PF00069	0.536
MOD_ProDKin_1	128	134	PF00069	0.506
MOD_ProDKin_1	162	168	PF00069	0.709
MOD_ProDKin_1	221	227	PF00069	0.639
MOD_ProDKin_1	234	240	PF00069	0.597
MOD_ProDKin_1	283	289	PF00069	0.671
MOD_ProDKin_1	295	301	PF00069	0.585
MOD_ProDKin_1	306	312	PF00069	0.596
MOD_ProDKin_1	331	337	PF00069	0.661
MOD_ProDKin_1	36	42	PF00069	0.642
MOD_ProDKin_1	4	10	PF00069	0.652
MOD_ProDKin_1	428	434	PF00069	0.648
MOD_ProDKin_1	446	452	PF00069	0.566
MOD_ProDKin_1	493	499	PF00069	0.634
MOD_ProDKin_1	50	56	PF00069	0.570
MOD_ProDKin_1	637	643	PF00069	0.596
MOD_ProDKin_1	679	685	PF00069	0.654
MOD_ProDKin_1	908	914	PF00069	0.755
MOD_ProDKin_1	91	97	PF00069	0.686
MOD_ProDKin_1	940	946	PF00069	0.765
MOD_SUMO_rev_2	147	156	PF00179	0.674
MOD_SUMO_rev_2	333	342	PF00179	0.616
MOD_SUMO_rev_2	393	401	PF00179	0.623
MOD_SUMO_rev_2	699	707	PF00179	0.613
TRG_DiLeu_BaLyEn_6	517	522	PF01217	0.636
TRG_ENDOCYTIC_2	33	36	PF00928	0.663
TRG_ENDOCYTIC_2	509	512	PF00928	0.551
TRG_ER_diArg_1	179	181	PF00400	0.527
TRG_ER_diArg_1	270	273	PF00400	0.624
TRG_ER_diArg_1	302	304	PF00400	0.690
TRG_ER_diArg_1	441	443	PF00400	0.597
TRG_ER_diArg_1	470	472	PF00400	0.560
TRG_ER_diArg_1	522	524	PF00400	0.638
TRG_ER_diArg_1	641	644	PF00400	0.687
TRG_ER_diArg_1	846	848	PF00400	0.668
TRG_ER_diArg_1	972	975	PF00400	0.578
TRG_Pf-PMV_PEXEL_1	829	833	PF00026	0.621

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H7S6	Leishmania braziliensis	52%	99%
A4I9W0	Leishmania infantum	99%	100%
E9B4X3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4Q354	Leishmania major	86%	100%