Ig-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IHA0_LEIDO

TriTrypDb:

LdBPK_342120.1 , LdCL_340028900 , LDHU3_34.3550

Length:

206

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IHA0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IHA0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	182	184	PF00675	0.471
CLV_NRD_NRD_1	48	50	PF00675	0.486
CLV_NRD_NRD_1	80	82	PF00675	0.515
CLV_PCSK_FUR_1	46	50	PF00082	0.492
CLV_PCSK_KEX2_1	182	184	PF00082	0.471
CLV_PCSK_KEX2_1	48	50	PF00082	0.624
CLV_PCSK_SKI1_1	38	42	PF00082	0.522
DOC_CYCLIN_RxL_1	167	178	PF00134	0.434
DOC_MAPK_gen_1	99	108	PF00069	0.611
DOC_USP7_MATH_1	12	16	PF00917	0.524
DOC_USP7_MATH_1	161	165	PF00917	0.381
DOC_USP7_MATH_1	26	30	PF00917	0.516
DOC_USP7_MATH_1	80	84	PF00917	0.538
LIG_14-3-3_CanoR_1	101	107	PF00244	0.524
LIG_14-3-3_CanoR_1	95	99	PF00244	0.646
LIG_BIR_II_1	1	5	PF00653	0.579
LIG_eIF4E_1	199	205	PF01652	0.549
LIG_FHA_1	103	109	PF00498	0.600
LIG_FHA_1	113	119	PF00498	0.460
LIG_FHA_1	121	127	PF00498	0.584
LIG_FHA_1	186	192	PF00498	0.590
LIG_FHA_2	187	193	PF00498	0.496
LIG_LIR_Gen_1	59	68	PF02991	0.461
LIG_LIR_Nem_3	192	196	PF02991	0.522
LIG_LIR_Nem_3	59	63	PF02991	0.432
LIG_SH2_NCK_1	199	203	PF00017	0.567
LIG_SH2_STAP1	96	100	PF00017	0.607
LIG_SH2_STAT5	96	99	PF00017	0.571
LIG_SH3_3	85	91	PF00018	0.761
LIG_SUMO_SIM_anti_2	104	110	PF11976	0.594
LIG_SUMO_SIM_anti_2	62	67	PF11976	0.389
MOD_CK1_1	14	20	PF00069	0.563
MOD_GSK3_1	11	18	PF00069	0.645
MOD_LATS_1	9	15	PF00433	0.570
MOD_N-GLC_1	118	123	PF02516	0.558
MOD_N-GLC_1	185	190	PF02516	0.507
MOD_NEK2_1	118	123	PF00069	0.535
MOD_NEK2_1	185	190	PF00069	0.560
MOD_NEK2_1	19	24	PF00069	0.564
MOD_NEK2_1	191	196	PF00069	0.547
MOD_PK_1	48	54	PF00069	0.481
MOD_PKA_1	48	54	PF00069	0.481
MOD_PKA_2	48	54	PF00069	0.499
MOD_PKA_2	80	86	PF00069	0.534
MOD_PKA_2	91	97	PF00069	0.503
MOD_PKB_1	46	54	PF00069	0.485
MOD_PKB_1	99	107	PF00069	0.717
MOD_Plk_1	191	197	PF00069	0.588
MOD_Plk_1	61	67	PF00069	0.455
MOD_Plk_4	104	110	PF00069	0.701
MOD_Plk_4	161	167	PF00069	0.439
MOD_Plk_4	61	67	PF00069	0.486
TRG_ER_diArg_1	182	184	PF00400	0.471
TRG_ER_diArg_1	47	49	PF00400	0.491

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IC33	Leptomonas seymouri	32%	100%
A4HAU7	Leishmania braziliensis	60%	100%
A4IA14	Leishmania infantum	99%	100%
E9B521	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q2W5	Leishmania major	90%	100%