Kelch motif/Galactose oxidase, central domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kelch motif containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IH28_LEIDO

TriTrypDb:

LdBPK_361530.1 , LdCL_360020800 , LDHU3_36.1960

Length:

1129

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3Q8IH28

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IH28

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	244	248	PF00656	0.489
CLV_C14_Caspase3-7	346	350	PF00656	0.613
CLV_C14_Caspase3-7	690	694	PF00656	0.540
CLV_C14_Caspase3-7	818	822	PF00656	0.542
CLV_C14_Caspase3-7	854	858	PF00656	0.557
CLV_C14_Caspase3-7	944	948	PF00656	0.555
CLV_NRD_NRD_1	1003	1005	PF00675	0.664
CLV_NRD_NRD_1	1013	1015	PF00675	0.533
CLV_NRD_NRD_1	1031	1033	PF00675	0.418
CLV_NRD_NRD_1	297	299	PF00675	0.428

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5A7	Leptomonas seymouri	42%	93%
A4HP07	Leishmania braziliensis	68%	100%
A4IDB6	Leishmania infantum	100%	100%
E9ASR7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4Q1S9	Leishmania major	88%	100%

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