Serine/threonine-protein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein phosphatase 2A catalytic subunit, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IH18_LEIDO

TriTrypDb:

LdBPK_323230.1 , LdCL_320038300 , LDHU3_32.4090

Length:

308

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Annotations by Jardim et al.

Phosphatase, Serine/threonine- phosphatase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 12
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 28

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IH18

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IH18

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006281	DNA repair	5	1
GO:0006302	double-strand break repair	6	1
GO:0006310	DNA recombination	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0046483	heterocycle metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0004721	phosphoprotein phosphatase activity	3	12
GO:0004722	protein serine/threonine phosphatase activity	4	12
GO:0016787	hydrolase activity	2	12
GO:0016788	hydrolase activity, acting on ester bonds	3	12
GO:0016791	phosphatase activity	5	12
GO:0017018	myosin phosphatase activity	5	12
GO:0042578	phosphoric ester hydrolase activity	4	12
GO:0140096	catalytic activity, acting on a protein	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	202	206	PF00656	0.433
CLV_NRD_NRD_1	107	109	PF00675	0.520
CLV_NRD_NRD_1	132	134	PF00675	0.399
CLV_NRD_NRD_1	182	184	PF00675	0.402
CLV_PCSK_KEX2_1	107	109	PF00082	0.520
CLV_PCSK_KEX2_1	182	184	PF00082	0.402
CLV_PCSK_KEX2_1	27	29	PF00082	0.571
CLV_PCSK_PC1ET2_1	27	29	PF00082	0.571
CLV_PCSK_SKI1_1	108	112	PF00082	0.415
CLV_PCSK_SKI1_1	119	123	PF00082	0.399
CLV_PCSK_SKI1_1	247	251	PF00082	0.449
CLV_PCSK_SKI1_1	282	286	PF00082	0.476
CLV_PCSK_SKI1_1	34	38	PF00082	0.474
DEG_Nend_Nbox_1	1	3	PF02207	0.702
DOC_MAPK_gen_1	102	111	PF00069	0.399
DOC_MAPK_gen_1	133	140	PF00069	0.399
DOC_USP7_MATH_1	152	156	PF00917	0.520
DOC_WW_Pin1_4	166	171	PF00397	0.399
DOC_WW_Pin1_4	207	212	PF00397	0.399
LIG_14-3-3_CanoR_1	119	128	PF00244	0.395
LIG_14-3-3_CanoR_1	142	151	PF00244	0.399
LIG_14-3-3_CanoR_1	87	93	PF00244	0.484
LIG_eIF4E_1	61	67	PF01652	0.484
LIG_FHA_1	1	7	PF00498	0.675
LIG_FHA_1	227	233	PF00498	0.433
LIG_FHA_1	74	80	PF00498	0.456
LIG_FHA_2	36	42	PF00498	0.548
LIG_LIR_Apic_2	195	201	PF02991	0.399
LIG_LIR_Apic_2	256	261	PF02991	0.407
LIG_LIR_Gen_1	145	156	PF02991	0.387
LIG_LIR_Gen_1	75	85	PF02991	0.399
LIG_LIR_Gen_1	86	97	PF02991	0.399
LIG_LIR_Nem_3	122	128	PF02991	0.399
LIG_LIR_Nem_3	145	151	PF02991	0.387
LIG_LIR_Nem_3	86	92	PF02991	0.442
LIG_LIR_Nem_3	93	98	PF02991	0.340
LIG_PCNA_yPIPBox_3	247	258	PF02747	0.476
LIG_PDZ_Class_2	303	308	PF00595	0.576
LIG_Pex14_2	80	84	PF04695	0.484
LIG_SH2_CRK	135	139	PF00017	0.399
LIG_SH2_STAP1	105	109	PF00017	0.456
LIG_SH2_STAP1	128	132	PF00017	0.399
LIG_SH2_STAT5	143	146	PF00017	0.399
LIG_SH2_STAT5	216	219	PF00017	0.399
LIG_SH2_STAT5	263	266	PF00017	0.457
LIG_SH2_STAT5	78	81	PF00017	0.399
LIG_SUMO_SIM_anti_2	93	100	PF11976	0.399
LIG_SUMO_SIM_par_1	252	259	PF11976	0.424
LIG_SUMO_SIM_par_1	272	278	PF11976	0.434
LIG_SUMO_SIM_par_1	3	10	PF11976	0.634
LIG_TRAF2_1	38	41	PF00917	0.602
LIG_TRFH_1	148	152	PF08558	0.415
LIG_UBA3_1	96	104	PF00899	0.400
LIG_WRC_WIRS_1	92	97	PF05994	0.399
MOD_CDK_SPK_2	207	212	PF00069	0.399
MOD_CK1_1	171	177	PF00069	0.405
MOD_CK1_1	91	97	PF00069	0.484
MOD_CK2_1	152	158	PF00069	0.504
MOD_CK2_1	196	202	PF00069	0.415
MOD_CK2_1	269	275	PF00069	0.419
MOD_CK2_1	35	41	PF00069	0.572
MOD_GlcNHglycan	258	261	PF01048	0.407
MOD_GSK3_1	115	122	PF00069	0.387
MOD_N-GLC_1	226	231	PF02516	0.484
MOD_N-GLC_1	250	255	PF02516	0.509
MOD_N-GLC_2	16	18	PF02516	0.555
MOD_N-GLC_2	262	264	PF02516	0.439
MOD_NEK2_1	226	231	PF00069	0.396
MOD_NEK2_1	250	255	PF00069	0.509
MOD_PIKK_1	119	125	PF00454	0.399
MOD_PK_1	134	140	PF00069	0.399
MOD_Plk_1	250	256	PF00069	0.503
MOD_Plk_4	152	158	PF00069	0.504
MOD_Plk_4	250	256	PF00069	0.448
MOD_Plk_4	269	275	PF00069	0.433
MOD_Plk_4	48	54	PF00069	0.399
MOD_Plk_4	91	97	PF00069	0.399
MOD_ProDKin_1	166	172	PF00069	0.399
MOD_ProDKin_1	207	213	PF00069	0.399
MOD_SUMO_rev_2	155	162	PF00179	0.520
MOD_SUMO_rev_2	19	29	PF00179	0.523
TRG_DiLeu_BaEn_1	93	98	PF01217	0.399
TRG_ENDOCYTIC_2	135	138	PF00928	0.399
TRG_ENDOCYTIC_2	246	249	PF00928	0.456
TRG_ENDOCYTIC_2	61	64	PF00928	0.467
TRG_ENDOCYTIC_2	78	81	PF00928	0.216
TRG_ENDOCYTIC_2	89	92	PF00928	0.399
TRG_ER_diArg_1	107	109	PF00400	0.486
TRG_ER_diArg_1	181	183	PF00400	0.520
TRG_NES_CRM1_1	275	288	PF08389	0.471
TRG_Pf-PMV_PEXEL_1	119	123	PF00026	0.399

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	43%	100%
A0A0N1HSR2	Leptomonas seymouri	39%	83%
A0A0N1I0V3	Leptomonas seymouri	40%	78%
A0A0N1IBK9	Leptomonas seymouri	97%	100%
A0A0N1ILH2	Leptomonas seymouri	33%	72%
A0A0N1P9X9	Leptomonas seymouri	59%	100%
A0A0N1PAV9	Leptomonas seymouri	47%	85%
A0A0N1PCC5	Leptomonas seymouri	50%	100%
A0A0N1PDK9	Leptomonas seymouri	59%	97%
A0A0S4IIW0	Bodo saltans	37%	78%
A0A0S4ILF8	Bodo saltans	85%	100%
A0A0S4J1J1	Bodo saltans	38%	79%
A0A0S4JDD1	Bodo saltans	42%	68%
A0A0S4JJ52	Bodo saltans	47%	81%
A0A0S4JJ96	Bodo saltans	41%	98%
A0A0S4JJH3	Bodo saltans	43%	98%
A0A0S4KGD7	Bodo saltans	61%	100%
A0A0S4KKU2	Bodo saltans	49%	100%
A0A0S4KLF4	Bodo saltans	29%	75%
A0A0S4KM73	Bodo saltans	40%	77%
A0A1X0NK88	Trypanosomatidae	43%	89%
A0A1X0NNN6	Trypanosomatidae	60%	92%
A0A1X0NS37	Trypanosomatidae	63%	100%
A0A1X0NS65	Trypanosomatidae	75%	100%
A0A1X0NUA6	Trypanosomatidae	37%	77%
A0A1X0NYR5	Trypanosomatidae	43%	100%
A0A1X0P6J3	Trypanosomatidae	40%	81%
A0A1X0P7H9	Trypanosomatidae	41%	69%
A0A1X0P7Q5	Trypanosomatidae	41%	80%
A0A1X0P982	Trypanosomatidae	41%	93%
A0A1X0P9R6	Trypanosomatidae	33%	68%
A0A1X0PA67	Trypanosomatidae	44%	100%
A0A1X0PAK9	Trypanosomatidae	42%	100%
A0A1X0PBJ2	Trypanosomatidae	48%	100%
A0A3Q8I8M6	Leishmania donovani	37%	71%
A0A3Q8IFB2	Leishmania donovani	43%	100%
A0A3Q8IHY7	Leishmania donovani	44%	100%
A0A3R7KQR6	Trypanosoma rangeli	60%	91%
A0A3R7M399	Trypanosoma rangeli	34%	71%
A0A3R7MBA3	Trypanosoma rangeli	40%	69%
A0A3R7MFZ7	Trypanosoma rangeli	40%	93%
A0A3R7MM48	Trypanosoma rangeli	38%	77%
A0A3R7N275	Trypanosoma rangeli	44%	100%
A0A3R7NP99	Trypanosoma rangeli	46%	100%
A0A3S5H6T9	Leishmania donovani	40%	82%
A0A3S5H7Q6	Leishmania donovani	46%	100%
A0A3S7WZ39	Leishmania donovani	59%	97%
A0A3S7X190	Leishmania donovani	43%	100%
A0A3S7X1Y0	Leishmania donovani	60%	100%
A0A3S7X7I6	Leishmania donovani	44%	100%
A0A3S7X7J8	Leishmania donovani	41%	100%
A0A3S7X7K2	Leishmania donovani	42%	100%
A0A3S7X8K6	Leishmania donovani	51%	100%
A0A3S7XAY3	Leishmania donovani	31%	76%
A0A422N8P1	Trypanosoma rangeli	43%	100%
A0A422N9D5	Trypanosoma rangeli	38%	78%
A0A422NKG0	Trypanosoma rangeli	60%	100%
A0A422NPG1	Trypanosoma rangeli	43%	89%
A0A422NYN7	Trypanosoma rangeli	72%	100%
A0A422P483	Trypanosoma rangeli	36%	72%
A0C1E4	Paramecium tetraurelia	70%	100%
A0CCD2	Paramecium tetraurelia	70%	100%
A0CNL9	Paramecium tetraurelia	55%	98%
A0DJ90	Paramecium tetraurelia	65%	100%
A2X2G3	Oryza sativa subsp. indica	59%	100%
A2XN40	Oryza sativa subsp. indica	59%	100%
A2YEB4	Oryza sativa subsp. indica	60%	100%
A3C4N5	Oryza sativa subsp. japonica	60%	98%
A4H6S0	Leishmania braziliensis	24%	73%
A4H7Z3	Leishmania braziliensis	39%	100%
A4HAI7	Leishmania braziliensis	43%	100%
A4HAI8	Leishmania braziliensis	43%	100%
A4HAI9	Leishmania braziliensis	44%	100%
A4HAJ8	Leishmania braziliensis	41%	100%
A4HBE2	Leishmania braziliensis	48%	100%
A4HE75	Leishmania braziliensis	60%	100%
A4HGA9	Leishmania braziliensis	45%	100%
A4HGX0	Leishmania braziliensis	65%	100%
A4HJQ1	Leishmania braziliensis	46%	100%
A4HKU9	Leishmania braziliensis	99%	100%
A4HP65	Leishmania braziliensis	32%	100%
A4HVT0	Leishmania infantum	37%	71%
A4HWC1	Leishmania infantum	40%	100%
A4I1H6	Leishmania infantum	58%	100%
A4I3E3	Leishmania infantum	44%	100%
A4I400	Leishmania infantum	60%	100%
A4I768	Leishmania infantum	46%	100%
A4I8C8	Leishmania infantum	100%	100%
A4I9P2	Leishmania infantum	41%	100%
A4IAJ0	Leishmania infantum	51%	100%
A4IDH0	Leishmania infantum	31%	100%
A6H772	Bos taurus	69%	100%
A8WGP3	Danio rerio	68%	99%
A8XE00	Caenorhabditis briggsae	68%	92%
A9JRC7	Danio rerio	68%	100%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	95%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	72%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	89%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	94%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	89%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	71%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	79%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	61%	100%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
E9AHS8	Leishmania infantum	43%	100%
E9AHS9	Leishmania infantum	42%	100%
E9AHT0	Leishmania infantum	43%	100%
E9AHT1	Leishmania infantum	43%	100%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	58%	100%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
G5EGK8	Caenorhabditis elegans	60%	97%
O00743	Homo sapiens	58%	100%
O02658	Caenorhabditis elegans	37%	100%
O04856	Nicotiana tabacum	44%	97%
O04857	Nicotiana tabacum	44%	99%
O04858	Nicotiana tabacum	44%	100%
O04860	Nicotiana tabacum	60%	98%
O04951	Arabidopsis thaliana	59%	100%
O15757	Dictyostelium discoideum	46%	96%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	55%	89%
O76932	Drosophila melanogaster	66%	100%
O82733	Arabidopsis thaliana	45%	93%
O82734	Arabidopsis thaliana	45%	95%
P0C5D7	Oryza sativa subsp. indica	60%	98%
P11084	Oryctolagus cuniculus	69%	100%
P11493	Sus scrofa	60%	100%
P11611	Oryctolagus cuniculus	59%	100%
P11612	Drosophila melanogaster	40%	98%
P12982	Drosophila melanogaster	48%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	46%	94%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	57%	99%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	47%	95%
P22198	Zea mays	43%	97%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	83%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	57%	82%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	57%	96%
P23696	Drosophila melanogaster	59%	100%
P23733	Trypanosoma brucei brucei	45%	89%
P23734	Trypanosoma brucei brucei	46%	89%
P23777	Brassica napus	47%	100%
P23778	Brassica napus	60%	100%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	45%	96%
P30366	Arabidopsis thaliana	46%	97%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	60%	100%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	99%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	84%
P34350	Caenorhabditis elegans	29%	81%
P34430	Caenorhabditis elegans	29%	100%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
P36873	Homo sapiens	48%	95%
P36874	Xenopus laevis	48%	95%
P48458	Caenorhabditis elegans	38%	85%
P48459	Caenorhabditis elegans	37%	68%
P48460	Caenorhabditis elegans	36%	68%
P48461	Drosophila melanogaster	45%	94%
P48462	Drosophila melanogaster	47%	93%
P48463	Gallus gallus	59%	100%
P48480	Acetabularia peniculus	45%	97%
P48481	Acetabularia peniculus	46%	97%
P48482	Arabidopsis thaliana	47%	99%
P48483	Arabidopsis thaliana	47%	96%
P48484	Arabidopsis thaliana	45%	96%
P48485	Arabidopsis thaliana	45%	99%
P48486	Arabidopsis thaliana	46%	96%
P48487	Brassica oleracea	45%	97%
P48488	Medicago sativa subsp. varia	48%	96%
P48489	Oryza sativa subsp. japonica	46%	96%
P48490	Phaseolus vulgaris	43%	98%
P48528	Arabidopsis thaliana	70%	100%
P48529	Arabidopsis thaliana	69%	100%
P48577	Acetabularia peniculus	57%	100%
P48578	Arabidopsis thaliana	60%	98%
P48579	Helianthus annuus	58%	100%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	58%	94%
P48726	Paramecium tetraurelia	55%	98%
P48727	Caenorhabditis elegans	49%	92%
P49576	Paramecium tetraurelia	65%	100%
P60510	Homo sapiens	69%	100%
P61287	Bos taurus	48%	95%
P61292	Sus scrofa	48%	94%
P62136	Homo sapiens	48%	93%
P62137	Mus musculus	48%	93%
P62138	Rattus norvegicus	48%	93%
P62139	Oryctolagus cuniculus	48%	93%
P62140	Homo sapiens	48%	94%
P62141	Mus musculus	48%	94%
P62142	Rattus norvegicus	48%	94%
P62143	Oryctolagus cuniculus	48%	94%
P62207	Gallus gallus	48%	94%
P62714	Homo sapiens	59%	100%
P62715	Mus musculus	59%	100%
P62716	Rattus norvegicus	59%	100%
P63087	Mus musculus	48%	95%
P63088	Rattus norvegicus	48%	95%
P63330	Mus musculus	59%	100%
P63331	Rattus norvegicus	59%	100%
P67774	Bos taurus	59%	100%
P67775	Homo sapiens	59%	100%
P67776	Sus scrofa	59%	100%
P67777	Oryctolagus cuniculus	59%	100%
P91420	Caenorhabditis elegans	36%	100%
P97470	Mus musculus	69%	100%
Q05547	Drosophila melanogaster	47%	100%
Q06009	Medicago sativa	60%	98%
Q07098	Arabidopsis thaliana	59%	100%
Q07099	Arabidopsis thaliana	60%	100%
Q07100	Arabidopsis thaliana	60%	98%
Q09496	Caenorhabditis elegans	50%	93%
Q0DBD3	Oryza sativa subsp. japonica	60%	100%
Q0E2S4	Oryza sativa subsp. japonica	59%	100%
Q0P594	Bos taurus	59%	100%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	54%	100%
Q10BT5	Oryza sativa subsp. japonica	59%	100%
Q27497	Caenorhabditis elegans	47%	94%
Q27884	Drosophila melanogaster	55%	100%
Q3SWW9	Bos taurus	48%	94%
Q3T0E7	Bos taurus	48%	93%
Q4Q1M5	Leishmania major	31%	100%
Q4Q2C2	Leishmania major	51%	100%
Q4Q3C0	Leishmania major	42%	100%
Q4Q3C5	Leishmania major	44%	100%
Q4Q3C6	Leishmania major	42%	100%
Q4Q3C7	Leishmania major	42%	100%
Q4Q3C8	Leishmania major	42%	100%
Q4Q4W8	Leishmania major	100%	100%
Q4Q5Z8	Leishmania major	46%	100%
Q4Q7Z5	Leishmania major	60%	100%
Q4Q8K1	Leishmania major	44%	100%
Q4Q9W1	Leishmania major	58%	100%
Q4QFG0	Leishmania major	40%	100%
Q4QG03	Leishmania major	41%	71%
Q4QGT8	Leishmania major	22%	73%
Q4WM22	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	57%	79%
Q54RD6	Dictyostelium discoideum	52%	99%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	56%	98%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	55%	74%
Q5BJ92	Rattus norvegicus	68%	100%
Q5I085	Xenopus tropicalis	48%	94%
Q5R6K8	Pongo abelii	69%	100%
Q5R740	Pongo abelii	48%	94%
Q61JR3	Caenorhabditis briggsae	47%	94%
Q627N3	Caenorhabditis briggsae	49%	92%
Q64620	Rattus norvegicus	58%	100%
Q6BFF6	Paramecium tetraurelia	54%	98%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	56%	100%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	58%	100%
Q6GQL2	Xenopus laevis	48%	94%
Q6IP91	Xenopus laevis	69%	100%
Q6NVU2	Xenopus tropicalis	48%	95%
Q6P861	Xenopus tropicalis	69%	100%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	59%	99%
Q7SZ10	Xenopus laevis	48%	95%
Q8LSN3	Pisum sativum	58%	100%
Q8MJ46	Canis lupus familiaris	48%	95%
Q8MJ47	Canis lupus familiaris	48%	94%
Q8SRZ0	Encephalitozoon cuniculi (strain GB-M1)	43%	67%
Q8WMS6	Canis lupus familiaris	48%	93%
Q8X178	Blumeria hordei	59%	94%
Q9CQR6	Mus musculus	58%	100%
Q9FN02	Arabidopsis thaliana	34%	75%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	59%	94%
Q9LHE7	Arabidopsis thaliana	58%	100%
Q9M9W3	Arabidopsis thaliana	46%	97%
Q9SX52	Arabidopsis thaliana	57%	100%
Q9U9A3	Dictyostelium discoideum	60%	100%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	47%	100%
Q9XGH7	Nicotiana tabacum	60%	99%
Q9XTT8	Caenorhabditis elegans	61%	96%
Q9XW79	Caenorhabditis elegans	68%	92%
Q9XZE5	Dictyostelium discoideum	56%	100%
Q9Y0B7	Dictyostelium discoideum	68%	100%
Q9ZSE4	Hevea brasiliensis	59%	100%
V5AUW3	Trypanosoma cruzi	40%	93%
V5B3V2	Trypanosoma cruzi	40%	81%
V5B5K9	Trypanosoma cruzi	75%	92%
V5B8G5	Trypanosoma cruzi	60%	91%
V5BBR3	Trypanosoma cruzi	36%	79%
V5BGM0	Trypanosoma cruzi	36%	77%
V5BKU4	Trypanosoma cruzi	45%	100%
V5BQD7	Trypanosoma cruzi	34%	70%
V5D2G9	Trypanosoma cruzi	43%	88%
V5DAX7	Trypanosoma cruzi	44%	100%
V5DCW3	Trypanosoma cruzi	60%	100%
V5DIG8	Trypanosoma cruzi	34%	71%
V5DMS5	Trypanosoma cruzi	47%	100%