Nsp1_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IH13_LEIDO

TriTrypDb:

LdCL_280038100

Length:

634

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IH13

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IH13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	5	9	PF00656	0.672
CLV_C14_Caspase3-7	85	89	PF00656	0.643
CLV_NRD_NRD_1	106	108	PF00675	0.764
CLV_NRD_NRD_1	29	31	PF00675	0.579
CLV_NRD_NRD_1	34	36	PF00675	0.523
CLV_NRD_NRD_1	43	45	PF00675	0.394
CLV_PCSK_KEX2_1	106	108	PF00082	0.748
CLV_PCSK_KEX2_1	29	31	PF00082	0.579
CLV_PCSK_SKI1_1	608	612	PF00082	0.743
DEG_SPOP_SBC_1	111	115	PF00917	0.737
DOC_PP4_MxPP_1	1	4	PF00568	0.716
DOC_USP7_MATH_1	105	109	PF00917	0.587
DOC_USP7_MATH_1	110	114	PF00917	0.501
DOC_USP7_MATH_1	130	134	PF00917	0.593
DOC_USP7_MATH_1	147	151	PF00917	0.802
DOC_USP7_MATH_1	451	455	PF00917	0.787
DOC_USP7_MATH_1	48	52	PF00917	0.545
DOC_USP7_MATH_1	485	489	PF00917	0.779
DOC_USP7_MATH_1	519	523	PF00917	0.775
DOC_USP7_MATH_1	589	593	PF00917	0.578
DOC_USP7_MATH_1	76	80	PF00917	0.671
DOC_USP7_MATH_1	94	98	PF00917	0.436
DOC_USP7_UBL2_3	68	72	PF12436	0.532
DOC_WW_Pin1_4	121	126	PF00397	0.741
DOC_WW_Pin1_4	148	153	PF00397	0.599
DOC_WW_Pin1_4	456	461	PF00397	0.785
DOC_WW_Pin1_4	490	495	PF00397	0.781
DOC_WW_Pin1_4	524	529	PF00397	0.782
DOC_WW_Pin1_4	578	583	PF00397	0.553
LIG_14-3-3_CanoR_1	164	174	PF00244	0.742
LIG_Actin_WH2_2	20	37	PF00022	0.481
LIG_BRCT_BRCA1_1	183	187	PF00533	0.603
LIG_BRCT_BRCA1_1	208	212	PF00533	0.543
LIG_BRCT_BRCA1_1	233	237	PF00533	0.528
LIG_BRCT_BRCA1_1	258	262	PF00533	0.636
LIG_BRCT_BRCA1_1	283	287	PF00533	0.629
LIG_BRCT_BRCA1_1	308	312	PF00533	0.533
LIG_BRCT_BRCA1_1	333	337	PF00533	0.635
LIG_BRCT_BRCA1_1	358	362	PF00533	0.538
LIG_BRCT_BRCA1_1	383	387	PF00533	0.545
LIG_BRCT_BRCA1_1	409	413	PF00533	0.571
LIG_BRCT_BRCA1_1	434	438	PF00533	0.728
LIG_BRCT_BRCA1_1	442	446	PF00533	0.757
LIG_BRCT_BRCA1_1	452	456	PF00533	0.630
LIG_BRCT_BRCA1_1	476	480	PF00533	0.774
LIG_BRCT_BRCA1_1	510	514	PF00533	0.772
LIG_BRCT_BRCA1_1	544	548	PF00533	0.734
LIG_BRCT_BRCA1_1	563	567	PF00533	0.480
LIG_BRCT_BRCA1_2	442	448	PF00533	0.791
LIG_BRCT_BRCA1_2	476	482	PF00533	0.777
LIG_BRCT_BRCA1_2	510	516	PF00533	0.774
LIG_BRCT_BRCA1_2	544	550	PF00533	0.732
LIG_CaM_IQ_9	21	37	PF13499	0.591
LIG_EH1_1	77	85	PF00400	0.658
LIG_FHA_1	16	22	PF00498	0.555
LIG_FHA_2	17	23	PF00498	0.650
LIG_FHA_2	65	71	PF00498	0.663
LIG_LIR_Gen_1	624	633	PF02991	0.695
LIG_LIR_Nem_3	624	629	PF02991	0.700
LIG_NRBOX	60	66	PF00104	0.681
LIG_Pex14_2	590	594	PF04695	0.748
LIG_SH2_PTP2	137	140	PF00017	0.561
LIG_SH2_SRC	137	140	PF00017	0.736
LIG_SH2_STAT5	137	140	PF00017	0.556
LIG_SH3_3	481	487	PF00018	0.596
LIG_SH3_3	515	521	PF00018	0.594
LIG_SH3_3	580	586	PF00018	0.545
MOD_CDK_SPxxK_3	148	155	PF00069	0.603
MOD_CK1_1	113	119	PF00069	0.737
MOD_CK1_1	124	130	PF00069	0.586
MOD_CK1_1	569	575	PF00069	0.726
MOD_CK1_1	578	584	PF00069	0.609
MOD_CK1_1	588	594	PF00069	0.494
MOD_CK1_1	609	615	PF00069	0.608
MOD_CK1_1	624	630	PF00069	0.632
MOD_CK2_1	106	112	PF00069	0.751
MOD_CK2_1	16	22	PF00069	0.658
MOD_CK2_1	48	54	PF00069	0.671
MOD_GlcNHglycan	108	111	PF01048	0.747
MOD_GlcNHglycan	183	186	PF01048	0.637
MOD_GlcNHglycan	208	211	PF01048	0.528
MOD_GlcNHglycan	233	236	PF01048	0.530
MOD_GlcNHglycan	258	261	PF01048	0.532
MOD_GlcNHglycan	283	286	PF01048	0.534
MOD_GlcNHglycan	308	311	PF01048	0.543
MOD_GlcNHglycan	333	336	PF01048	0.540
MOD_GlcNHglycan	358	361	PF01048	0.548
MOD_GlcNHglycan	383	386	PF01048	0.554
MOD_GlcNHglycan	409	412	PF01048	0.581
MOD_GlcNHglycan	434	437	PF01048	0.633
MOD_GlcNHglycan	453	456	PF01048	0.714
MOD_GlcNHglycan	487	490	PF01048	0.789
MOD_GlcNHglycan	521	524	PF01048	0.783
MOD_GlcNHglycan	558	561	PF01048	0.713
MOD_GlcNHglycan	563	566	PF01048	0.661
MOD_GlcNHglycan	568	571	PF01048	0.592
MOD_GlcNHglycan	577	580	PF01048	0.491
MOD_GlcNHglycan	587	590	PF01048	0.484
MOD_GlcNHglycan	591	594	PF01048	0.520
MOD_GlcNHglycan	608	611	PF01048	0.524
MOD_GlcNHglycan	618	621	PF01048	0.582
MOD_GSK3_1	106	113	PF00069	0.748
MOD_GSK3_1	12	19	PF00069	0.668
MOD_GSK3_1	177	184	PF00069	0.735
MOD_GSK3_1	202	209	PF00069	0.748
MOD_GSK3_1	227	234	PF00069	0.571
MOD_GSK3_1	252	259	PF00069	0.774
MOD_GSK3_1	277	284	PF00069	0.569
MOD_GSK3_1	302	309	PF00069	0.748
MOD_GSK3_1	327	334	PF00069	0.577
MOD_GSK3_1	352	359	PF00069	0.759
MOD_GSK3_1	377	384	PF00069	0.587
MOD_GSK3_1	428	435	PF00069	0.625
MOD_GSK3_1	566	573	PF00069	0.726
MOD_GSK3_1	584	591	PF00069	0.494
MOD_GSK3_1	602	609	PF00069	0.515
MOD_GSK3_1	621	628	PF00069	0.458
MOD_N-GLC_1	95	100	PF02516	0.686
MOD_NEK2_1	165	170	PF00069	0.609
MOD_NEK2_1	56	61	PF00069	0.563
MOD_NEK2_1	621	626	PF00069	0.712
MOD_NEK2_1	82	87	PF00069	0.640
MOD_PIKK_1	95	101	PF00454	0.686
MOD_PKA_1	106	112	PF00069	0.698
MOD_PKA_2	105	111	PF00069	0.710
MOD_PKA_2	160	166	PF00069	0.767
MOD_Plk_1	130	136	PF00069	0.570
MOD_Plk_1	49	55	PF00069	0.644
MOD_Plk_4	114	120	PF00069	0.593
MOD_Plk_4	124	130	PF00069	0.662
MOD_ProDKin_1	121	127	PF00069	0.738
MOD_ProDKin_1	148	154	PF00069	0.601
MOD_ProDKin_1	456	462	PF00069	0.785
MOD_ProDKin_1	490	496	PF00069	0.781
MOD_ProDKin_1	524	530	PF00069	0.783
MOD_ProDKin_1	578	584	PF00069	0.553
TRG_DiLeu_BaLyEn_6	60	65	PF01217	0.504
TRG_ER_diArg_1	29	31	PF00400	0.579

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B0C4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	72%