Ribosomal_protein_L24_putative/GeneDB:LmjF.36.107 0/GeneDB:LmjF.36.1100

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L24, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IH09_LEIDO

TriTrypDb:

LdCL_360016400 , LdCL_360016700 , LDHU3_36.1470 , LDHU3_36.1500

Length:

124

Annotations

Annotations by Jardim et al.

Ribosomal Protein, ribosomal L24

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	10
GO:0043226	organelle	2	10
GO:0043228	non-membrane-bounded organelle	3	10
GO:0043229	intracellular organelle	3	10
GO:0043232	intracellular non-membrane-bounded organelle	4	10
GO:0110165	cellular anatomical entity	1	11
GO:0005737	cytoplasm	2	1
GO:0015934	large ribosomal subunit	4	1
GO:0022625	cytosolic large ribosomal subunit	5	1
GO:0032991	protein-containing complex	1	1
GO:0044391	ribosomal subunit	3	1
GO:1990904	ribonucleoprotein complex	2	1

Phosphorylation

Promastigote: 92

Expansion

Sequence features

A0A3Q8IH09

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IH09

Function

Biological processes
Term	Name	Level	Count
GO:0002181	cytoplasmic translation	5	1
GO:0006412	translation	4	1
GO:0006518	peptide metabolic process	4	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0009987	cellular process	1	1
GO:0019538	protein metabolic process	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	1
GO:0043043	peptide biosynthetic process	5	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043603	amide metabolic process	3	1
GO:0043604	amide biosynthetic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0003729	mRNA binding	5	1
GO:0003735	structural constituent of ribosome	2	1
GO:0005198	structural molecule activity	1	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	100	102	PF00675	0.667
CLV_NRD_NRD_1	118	120	PF00675	0.401
CLV_NRD_NRD_1	19	21	PF00675	0.320
CLV_NRD_NRD_1	45	47	PF00675	0.320
CLV_NRD_NRD_1	60	62	PF00675	0.320
CLV_NRD_NRD_1	63	65	PF00675	0.320
CLV_NRD_NRD_1	74	76	PF00675	0.589
CLV_PCSK_KEX2_1	19	21	PF00082	0.320
CLV_PCSK_KEX2_1	60	62	PF00082	0.320
CLV_PCSK_KEX2_1	73	75	PF00082	0.598
CLV_PCSK_PC7_1	70	76	PF00082	0.597
CLV_PCSK_SKI1_1	105	109	PF00082	0.541
CLV_PCSK_SKI1_1	120	124	PF00082	0.565
CLV_PCSK_SKI1_1	30	34	PF00082	0.320
DEG_Nend_UBRbox_1	1	4	PF02207	0.520
DOC_MAPK_gen_1	73	82	PF00069	0.672
DOC_PP4_FxxP_1	35	38	PF00568	0.534
DOC_USP7_UBL2_3	120	124	PF12436	0.565
LIG_14-3-3_CanoR_1	64	71	PF00244	0.534
LIG_FHA_1	27	33	PF00498	0.522
LIG_FHA_1	66	72	PF00498	0.543
LIG_FHA_2	64	70	PF00498	0.534
LIG_LIR_Apic_2	34	38	PF02991	0.534
LIG_LIR_Gen_1	5	15	PF02991	0.526
LIG_LIR_Nem_3	5	11	PF02991	0.526
LIG_LIR_Nem_3	56	62	PF02991	0.528
LIG_Pex14_1	55	59	PF04695	0.537
LIG_PTB_Apo_2	46	53	PF02174	0.520
LIG_SH2_CRK	59	63	PF00017	0.520
LIG_SH2_STAT5	21	24	PF00017	0.533
LIG_SH2_STAT5	93	96	PF00017	0.485
LIG_WRC_WIRS_1	32	37	PF05994	0.533
MOD_Cter_Amidation	17	20	PF01082	0.320
MOD_GlcNHglycan	103	108	PF01048	0.580
MOD_LATS_1	63	69	PF00433	0.534
MOD_NEK2_1	26	31	PF00069	0.521
MOD_NEK2_1	33	38	PF00069	0.537
MOD_PKA_1	64	70	PF00069	0.534
MOD_PKA_2	63	69	PF00069	0.534
MOD_Plk_1	6	12	PF00069	0.534
MOD_Plk_1	89	95	PF00069	0.472
MOD_Plk_4	89	95	PF00069	0.472
MOD_SUMO_rev_2	115	122	PF00179	0.543
TRG_ENDOCYTIC_2	21	24	PF00928	0.533
TRG_ENDOCYTIC_2	59	62	PF00928	0.533
TRG_ER_diArg_1	19	21	PF00400	0.520
TRG_ER_diArg_1	59	61	PF00400	0.520
TRG_ER_diArg_1	73	75	PF00400	0.598
TRG_NLS_MonoExtC_3	45	50	PF00514	0.520

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYL9	Leptomonas seymouri	96%	100%
A0A0S4JCV0	Bodo saltans	84%	99%
A0A1X0P816	Trypanosomatidae	87%	99%
A0A3R7KJR7	Trypanosoma rangeli	86%	99%
A4HNW7	Leishmania braziliensis	98%	100%
A4ICM4	Leishmania infantum	100%	100%
D0A2T5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	86%	99%
E9ASM7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
O01868	Caenorhabditis elegans	33%	78%
O65743	Cicer arietinum	32%	76%
O74884	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	83%
P04449	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	80%
P0DJ54	Tetrahymena thermophila (strain SB210)	32%	78%
P24000	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	80%
P38665	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	39%	80%
P38666	Arabidopsis thaliana	36%	76%
P50888	Hordeum vulgare	32%	77%
P61122	Macaca fascicularis	40%	79%
P83731	Homo sapiens	40%	79%
P83732	Rattus norvegicus	40%	79%
Q42347	Arabidopsis thaliana	36%	76%
Q4Q1W6	Leishmania major	99%	100%
Q54VN6	Dictyostelium discoideum	37%	98%
Q5A6A1	Candida albicans (strain SC5314 / ATCC MYA-2876)	37%	80%
Q66WF5	Felis catus	40%	79%
Q6BNC2	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	36%	79%
Q6C4U6	Yarrowia lipolytica (strain CLIB 122 / E 150)	39%	80%
Q6F444	Plutella xylostella	35%	80%
Q6FXY9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	39%	80%
Q6Y263	Pagrus major	43%	79%
Q752U6	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	40%	80%
Q7SDU2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	79%
Q7Z0T8	Schistosoma japonicum	32%	79%
Q862I1	Bos taurus	40%	79%
Q8BP67	Mus musculus	40%	79%
Q8ISQ3	Branchiostoma belcheri	38%	81%
Q8JGR4	Danio rerio	43%	79%
Q90YU3	Ictalurus punctatus	41%	79%
Q92354	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	83%
Q962T5	Spodoptera frugiperda	36%	80%
Q9DFQ7	Gillichthys mirabilis	43%	79%
Q9FUL4	Prunus avium	32%	67%
Q9VJY6	Drosophila melanogaster	39%	80%