SDA1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IH03_LEIDO

TriTrypDb:

LdBPK_321880.1 , LdCL_320024300 , LDHU3_32.2370

Length:

233

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IH03

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IH03

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	108	112	PF00656	0.633
CLV_NRD_NRD_1	143	145	PF00675	0.673
CLV_NRD_NRD_1	183	185	PF00675	0.598
CLV_NRD_NRD_1	19	21	PF00675	0.556
CLV_NRD_NRD_1	224	226	PF00675	0.677
CLV_NRD_NRD_1	45	47	PF00675	0.523
CLV_NRD_NRD_1	66	68	PF00675	0.541
CLV_PCSK_KEX2_1	142	144	PF00082	0.677
CLV_PCSK_KEX2_1	183	185	PF00082	0.813
CLV_PCSK_KEX2_1	19	21	PF00082	0.556
CLV_PCSK_KEX2_1	31	33	PF00082	0.449
CLV_PCSK_KEX2_1	38	40	PF00082	0.443
CLV_PCSK_KEX2_1	66	68	PF00082	0.541
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.551
CLV_PCSK_PC1ET2_1	38	40	PF00082	0.443
CLV_PCSK_SKI1_1	23	27	PF00082	0.555
DEG_Nend_UBRbox_1	1	4	PF02207	0.704
DOC_MAPK_gen_1	26	36	PF00069	0.541
DOC_USP7_MATH_1	12	16	PF00917	0.618
DOC_USP7_MATH_1	228	232	PF00917	0.658
DOC_USP7_MATH_1	84	88	PF00917	0.704
DOC_USP7_MATH_1	99	103	PF00917	0.715
DOC_USP7_UBL2_3	77	81	PF12436	0.693
LIG_14-3-3_CanoR_1	118	125	PF00244	0.589
LIG_14-3-3_CanoR_1	211	220	PF00244	0.737
LIG_BRCT_BRCA1_1	6	10	PF00533	0.707
LIG_FHA_1	227	233	PF00498	0.662
LIG_FHA_1	28	34	PF00498	0.545
LIG_RPA_C_Fungi	138	150	PF08784	0.655
LIG_SH2_STAT5	63	66	PF00017	0.547
LIG_TRAF2_1	49	52	PF00917	0.556
MOD_CK1_1	110	116	PF00069	0.695
MOD_CK1_1	54	60	PF00069	0.542
MOD_CK2_1	12	18	PF00069	0.581
MOD_CK2_1	216	222	PF00069	0.595
MOD_CK2_1	94	100	PF00069	0.665
MOD_Cter_Amidation	181	184	PF01082	0.600
MOD_GlcNHglycan	120	123	PF01048	0.758
MOD_GlcNHglycan	192	195	PF01048	0.758
MOD_GlcNHglycan	200	203	PF01048	0.720
MOD_GlcNHglycan	85	89	PF01048	0.714
MOD_GlcNHglycan	96	99	PF01048	0.732
MOD_GSK3_1	107	114	PF00069	0.635
MOD_GSK3_1	212	219	PF00069	0.712
MOD_LATS_1	209	215	PF00433	0.744
MOD_N-GLC_1	212	217	PF02516	0.815
MOD_NEK2_1	27	32	PF00069	0.554
MOD_NEK2_1	59	64	PF00069	0.546
MOD_NEK2_2	228	233	PF00069	0.665
MOD_PKA_2	198	204	PF00069	0.790
MOD_PKA_2	205	211	PF00069	0.701
MOD_Plk_1	110	116	PF00069	0.664
MOD_Plk_1	51	57	PF00069	0.549
MOD_Plk_4	59	65	PF00069	0.547
TRG_ER_diArg_1	142	144	PF00400	0.774
TRG_ER_diArg_1	65	67	PF00400	0.542
TRG_NLS_Bipartite_1	19	41	PF00514	0.554
TRG_NLS_MonoExtN_4	35	41	PF00514	0.477

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFN4	Leptomonas seymouri	52%	100%
A4HKG7	Leishmania braziliensis	60%	95%
A4I7Z4	Leishmania infantum	94%	100%
E9B2V6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q5A0	Leishmania major	82%	100%