Calphotin-like_protein/GeneDB:LmjF.36.6860

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IGY1_LEIDO

TriTrypDb:

LdBPK_367190.1 , LdCL_360084500 , LDHU3_36.9560

Length:

429

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGY1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGY1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	245	249	PF00656	0.685
CLV_NRD_NRD_1	282	284	PF00675	0.584
CLV_NRD_NRD_1	299	301	PF00675	0.534
CLV_PCSK_KEX2_1	188	190	PF00082	0.772
CLV_PCSK_KEX2_1	282	284	PF00082	0.587
CLV_PCSK_KEX2_1	298	300	PF00082	0.565
CLV_PCSK_KEX2_1	305	307	PF00082	0.552
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.772
CLV_PCSK_PC1ET2_1	282	284	PF00082	0.577
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.470
CLV_PCSK_PC1ET2_1	305	307	PF00082	0.543
CLV_PCSK_SKI1_1	17	21	PF00082	0.724
CLV_PCSK_SKI1_1	185	189	PF00082	0.627
CLV_PCSK_SKI1_1	221	225	PF00082	0.703
CLV_PCSK_SKI1_1	351	355	PF00082	0.636
DEG_APCC_DBOX_1	410	418	PF00400	0.659
DEG_SCF_FBW7_1	392	399	PF00400	0.570
DOC_CKS1_1	393	398	PF01111	0.636
DOC_MAPK_MEF2A_6	330	338	PF00069	0.531
DOC_PP1_RVXF_1	15	22	PF00149	0.722
DOC_PP1_RVXF_1	199	205	PF00149	0.537
DOC_PP2B_LxvP_1	56	59	PF13499	0.723
DOC_PP4_FxxP_1	270	273	PF00568	0.566
DOC_USP7_MATH_1	384	388	PF00917	0.695
DOC_USP7_MATH_1	397	401	PF00917	0.547
DOC_WW_Pin1_4	117	122	PF00397	0.706
DOC_WW_Pin1_4	269	274	PF00397	0.600
DOC_WW_Pin1_4	3	8	PF00397	0.728
DOC_WW_Pin1_4	31	36	PF00397	0.685
DOC_WW_Pin1_4	317	322	PF00397	0.497
DOC_WW_Pin1_4	392	397	PF00397	0.674
DOC_WW_Pin1_4	409	414	PF00397	0.792
DOC_WW_Pin1_4	63	68	PF00397	0.658
DOC_WW_Pin1_4	9	14	PF00397	0.694
LIG_14-3-3_CanoR_1	143	150	PF00244	0.645
LIG_14-3-3_CanoR_1	178	184	PF00244	0.628
LIG_14-3-3_CanoR_1	189	197	PF00244	0.523
LIG_14-3-3_CanoR_1	228	234	PF00244	0.797
LIG_14-3-3_CanoR_1	73	80	PF00244	0.703
LIG_BIR_II_1	1	5	PF00653	0.791
LIG_EVH1_2	121	125	PF00568	0.714
LIG_FHA_1	18	24	PF00498	0.774
LIG_FHA_1	188	194	PF00498	0.615
LIG_FHA_1	241	247	PF00498	0.676
LIG_FHA_1	26	32	PF00498	0.652
LIG_FHA_1	308	314	PF00498	0.523
LIG_FHA_2	243	249	PF00498	0.682
LIG_FHA_2	73	79	PF00498	0.819
LIG_LIR_Gen_1	160	169	PF02991	0.590
LIG_LIR_Nem_3	160	164	PF02991	0.640
LIG_LIR_Nem_3	291	297	PF02991	0.628
LIG_LIR_Nem_3	344	350	PF02991	0.519
LIG_LYPXL_S_1	108	112	PF13949	0.672
LIG_LYPXL_yS_3	109	112	PF13949	0.678
LIG_MYND_1	39	43	PF01753	0.620
LIG_PCNA_PIPBox_1	208	217	PF02747	0.581
LIG_PDZ_Class_1	424	429	PF00595	0.576
LIG_Pex14_1	265	269	PF04695	0.542
LIG_SH2_CRK	98	102	PF00017	0.571
LIG_SH2_STAT5	161	164	PF00017	0.689
LIG_SH2_STAT5	215	218	PF00017	0.623
LIG_SH2_STAT5	269	272	PF00017	0.558
LIG_SH2_STAT5	294	297	PF00017	0.618
LIG_SH3_3	1	7	PF00018	0.723
LIG_SH3_3	174	180	PF00018	0.663
LIG_SH3_3	30	36	PF00018	0.664
LIG_SH3_3	362	368	PF00018	0.567
LIG_SH3_3	390	396	PF00018	0.612
LIG_SH3_3	40	46	PF00018	0.766
LIG_SH3_3	56	62	PF00018	0.745
LIG_SH3_3	64	70	PF00018	0.585
LIG_SUMO_SIM_anti_2	332	340	PF11976	0.541
LIG_SUMO_SIM_par_1	179	184	PF11976	0.708
LIG_SUMO_SIM_par_1	332	340	PF11976	0.541
LIG_TRAF2_1	74	77	PF00917	0.742
LIG_Vh1_VBS_1	324	342	PF01044	0.481
LIG_WW_1	158	161	PF00397	0.643
MOD_CK1_1	117	123	PF00069	0.720
MOD_CK1_1	170	176	PF00069	0.666
MOD_CK1_1	229	235	PF00069	0.718
MOD_CK1_1	3	9	PF00069	0.703
MOD_CK1_1	317	323	PF00069	0.491
MOD_CK1_1	355	361	PF00069	0.566
MOD_CK2_1	142	148	PF00069	0.729
MOD_CK2_1	275	281	PF00069	0.424
MOD_CK2_1	72	78	PF00069	0.770
MOD_GlcNHglycan	116	119	PF01048	0.745
MOD_GlcNHglycan	137	140	PF01048	0.554
MOD_GlcNHglycan	169	172	PF01048	0.574
MOD_GlcNHglycan	23	26	PF01048	0.751
MOD_GlcNHglycan	290	293	PF01048	0.580
MOD_GlcNHglycan	339	342	PF01048	0.567
MOD_GlcNHglycan	354	357	PF01048	0.381
MOD_GSK3_1	113	120	PF00069	0.701
MOD_GSK3_1	17	24	PF00069	0.744
MOD_GSK3_1	227	234	PF00069	0.724
MOD_GSK3_1	240	247	PF00069	0.560
MOD_GSK3_1	392	399	PF00069	0.674
MOD_NEK2_1	113	118	PF00069	0.687
MOD_NEK2_1	181	186	PF00069	0.655
MOD_NEK2_1	21	26	PF00069	0.706
MOD_NEK2_1	337	342	PF00069	0.554
MOD_PK_1	330	336	PF00069	0.435
MOD_PKA_1	17	23	PF00069	0.724
MOD_PKA_1	188	194	PF00069	0.580
MOD_PKA_2	142	148	PF00069	0.651
MOD_PKA_2	167	173	PF00069	0.577
MOD_PKA_2	188	194	PF00069	0.634
MOD_PKA_2	227	233	PF00069	0.686
MOD_PKA_2	342	348	PF00069	0.579
MOD_PKA_2	72	78	PF00069	0.708
MOD_Plk_1	343	349	PF00069	0.451
MOD_Plk_4	275	281	PF00069	0.467
MOD_Plk_4	307	313	PF00069	0.478
MOD_Plk_4	330	336	PF00069	0.474
MOD_Plk_4	361	367	PF00069	0.494
MOD_ProDKin_1	117	123	PF00069	0.708
MOD_ProDKin_1	269	275	PF00069	0.598
MOD_ProDKin_1	3	9	PF00069	0.726
MOD_ProDKin_1	31	37	PF00069	0.686
MOD_ProDKin_1	317	323	PF00069	0.491
MOD_ProDKin_1	392	398	PF00069	0.677
MOD_ProDKin_1	409	415	PF00069	0.791
MOD_ProDKin_1	63	69	PF00069	0.659
MOD_SUMO_for_1	216	219	PF00179	0.600
MOD_SUMO_for_1	91	94	PF00179	0.588
TRG_DiLeu_BaLyEn_6	67	72	PF01217	0.681
TRG_ENDOCYTIC_2	109	112	PF00928	0.659
TRG_ENDOCYTIC_2	161	164	PF00928	0.665
TRG_ENDOCYTIC_2	215	218	PF00928	0.623
TRG_ENDOCYTIC_2	98	101	PF00928	0.670
TRG_NLS_Bipartite_1	282	302	PF00514	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HQK7	Leishmania braziliensis	68%	100%
A4ICC7	Leishmania infantum	100%	100%
E9AUC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q068	Leishmania major	87%	100%