Glycosylation, Dolicholphosphate-mannose synthase DPMS
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 18 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | 5 | 12 |
| GO:0016020 | membrane | 2 | 10 |
| GO:0043226 | organelle | 2 | 12 |
| GO:0043227 | membrane-bounded organelle | 3 | 12 |
| GO:0043229 | intracellular organelle | 3 | 12 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 12 |
| GO:0110165 | cellular anatomical entity | 1 | 12 |
| GO:0005635 | nuclear envelope | 4 | 1 |
| GO:0005789 | endoplasmic reticulum membrane | 4 | 1 |
| GO:0031090 | organelle membrane | 3 | 1 |
| GO:0031967 | organelle envelope | 3 | 1 |
| GO:0031975 | envelope | 2 | 1 |
Related structures:
AlphaFold database: A0A3Q8IGV1
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006486 | protein glycosylation | 4 | 12 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 12 |
| GO:0008152 | metabolic process | 1 | 12 |
| GO:0019538 | protein metabolic process | 3 | 12 |
| GO:0036211 | protein modification process | 4 | 12 |
| GO:0043170 | macromolecule metabolic process | 3 | 12 |
| GO:0043412 | macromolecule modification | 4 | 12 |
| GO:0043413 | macromolecule glycosylation | 3 | 12 |
| GO:0044238 | primary metabolic process | 2 | 12 |
| GO:0070085 | glycosylation | 2 | 12 |
| GO:0071704 | organic substance metabolic process | 2 | 12 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 12 |
| GO:0006066 | alcohol metabolic process | 3 | 1 |
| GO:0006493 | protein O-linked glycosylation | 5 | 1 |
| GO:0006497 | protein lipidation | 5 | 1 |
| GO:0006505 | GPI anchor metabolic process | 6 | 1 |
| GO:0006506 | GPI anchor biosynthetic process | 6 | 1 |
| GO:0006629 | lipid metabolic process | 3 | 1 |
| GO:0006643 | membrane lipid metabolic process | 4 | 1 |
| GO:0006644 | phospholipid metabolic process | 4 | 1 |
| GO:0006650 | glycerophospholipid metabolic process | 5 | 1 |
| GO:0006661 | phosphatidylinositol biosynthetic process | 6 | 1 |
| GO:0006664 | glycolipid metabolic process | 5 | 1 |
| GO:0006720 | isoprenoid metabolic process | 4 | 1 |
| GO:0006793 | phosphorus metabolic process | 3 | 1 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 1 |
| GO:0008610 | lipid biosynthetic process | 4 | 1 |
| GO:0008654 | phospholipid biosynthetic process | 5 | 1 |
| GO:0009058 | biosynthetic process | 2 | 1 |
| GO:0009247 | glycolipid biosynthetic process | 5 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0016093 | polyprenol metabolic process | 4 | 1 |
| GO:0019348 | dolichol metabolic process | 5 | 1 |
| GO:0019637 | organophosphate metabolic process | 3 | 1 |
| GO:0035268 | protein mannosylation | 4 | 1 |
| GO:0035269 | protein O-linked mannosylation | 5 | 1 |
| GO:0044237 | cellular metabolic process | 2 | 1 |
| GO:0044249 | cellular biosynthetic process | 3 | 1 |
| GO:0044255 | cellular lipid metabolic process | 3 | 1 |
| GO:0044281 | small molecule metabolic process | 2 | 1 |
| GO:0045017 | glycerolipid biosynthetic process | 4 | 1 |
| GO:0046467 | membrane lipid biosynthetic process | 4 | 1 |
| GO:0046474 | glycerophospholipid biosynthetic process | 5 | 1 |
| GO:0046486 | glycerolipid metabolic process | 4 | 1 |
| GO:0046488 | phosphatidylinositol metabolic process | 6 | 1 |
| GO:0090407 | organophosphate biosynthetic process | 4 | 1 |
| GO:0097502 | mannosylation | 3 | 1 |
| GO:1901135 | carbohydrate derivative metabolic process | 3 | 1 |
| GO:1901137 | carbohydrate derivative biosynthetic process | 4 | 1 |
| GO:1901576 | organic substance biosynthetic process | 3 | 1 |
| GO:1901615 | organic hydroxy compound metabolic process | 3 | 1 |
| GO:1903509 | liposaccharide metabolic process | 4 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000030 | mannosyltransferase activity | 5 | 12 |
| GO:0003824 | catalytic activity | 1 | 12 |
| GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity | 6 | 12 |
| GO:0016740 | transferase activity | 2 | 12 |
| GO:0016757 | glycosyltransferase activity | 3 | 12 |
| GO:0016758 | hexosyltransferase activity | 4 | 12 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 139 | 141 | PF00675 | 0.206 |
| CLV_NRD_NRD_1 | 21 | 23 | PF00675 | 0.310 |
| CLV_PCSK_KEX2_1 | 139 | 141 | PF00082 | 0.206 |
| CLV_PCSK_KEX2_1 | 172 | 174 | PF00082 | 0.281 |
| CLV_PCSK_KEX2_1 | 21 | 23 | PF00082 | 0.248 |
| CLV_PCSK_PC1ET2_1 | 172 | 174 | PF00082 | 0.310 |
| CLV_PCSK_SKI1_1 | 151 | 155 | PF00082 | 0.206 |
| CLV_PCSK_SKI1_1 | 184 | 188 | PF00082 | 0.261 |
| CLV_PCSK_SKI1_1 | 21 | 25 | PF00082 | 0.240 |
| CLV_PCSK_SKI1_1 | 218 | 222 | PF00082 | 0.348 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.574 |
| DOC_MAPK_gen_1 | 234 | 243 | PF00069 | 0.421 |
| DOC_MAPK_MEF2A_6 | 184 | 191 | PF00069 | 0.420 |
| DOC_MAPK_MEF2A_6 | 237 | 245 | PF00069 | 0.497 |
| DOC_MAPK_NFAT4_5 | 184 | 192 | PF00069 | 0.430 |
| DOC_PP1_RVXF_1 | 138 | 145 | PF00149 | 0.417 |
| DOC_PP1_RVXF_1 | 216 | 222 | PF00149 | 0.588 |
| DOC_USP7_UBL2_3 | 214 | 218 | PF12436 | 0.514 |
| LIG_14-3-3_CanoR_1 | 139 | 145 | PF00244 | 0.414 |
| LIG_14-3-3_CanoR_1 | 151 | 157 | PF00244 | 0.463 |
| LIG_14-3-3_CanoR_1 | 69 | 75 | PF00244 | 0.409 |
| LIG_14-3-3_CanoR_1 | 84 | 92 | PF00244 | 0.397 |
| LIG_APCC_ABBA_1 | 62 | 67 | PF00400 | 0.405 |
| LIG_BRCT_BRCA1_1 | 160 | 164 | PF00533 | 0.406 |
| LIG_FHA_1 | 214 | 220 | PF00498 | 0.510 |
| LIG_FHA_1 | 32 | 38 | PF00498 | 0.493 |
| LIG_FHA_2 | 153 | 159 | PF00498 | 0.452 |
| LIG_FHA_2 | 207 | 213 | PF00498 | 0.548 |
| LIG_GBD_Chelix_1 | 253 | 261 | PF00786 | 0.395 |
| LIG_HCF-1_HBM_1 | 225 | 228 | PF13415 | 0.458 |
| LIG_LIR_Nem_3 | 161 | 166 | PF02991 | 0.450 |
| LIG_LIR_Nem_3 | 225 | 231 | PF02991 | 0.555 |
| LIG_LIR_Nem_3 | 87 | 93 | PF02991 | 0.450 |
| LIG_MLH1_MIPbox_1 | 160 | 164 | PF16413 | 0.417 |
| LIG_PDZ_Class_1 | 257 | 262 | PF00595 | 0.410 |
| LIG_REV1ctd_RIR_1 | 161 | 171 | PF16727 | 0.417 |
| LIG_SH2_CRK | 258 | 262 | PF00017 | 0.302 |
| LIG_SH2_CRK | 3 | 7 | PF00017 | 0.417 |
| LIG_SH2_CRK | 90 | 94 | PF00017 | 0.510 |
| LIG_SH2_PTP2 | 240 | 243 | PF00017 | 0.347 |
| LIG_SH2_SRC | 223 | 226 | PF00017 | 0.490 |
| LIG_SH2_STAP1 | 228 | 232 | PF00017 | 0.486 |
| LIG_SH2_STAP1 | 3 | 7 | PF00017 | 0.417 |
| LIG_SH2_STAT5 | 223 | 226 | PF00017 | 0.465 |
| LIG_SH2_STAT5 | 231 | 234 | PF00017 | 0.454 |
| LIG_SH2_STAT5 | 240 | 243 | PF00017 | 0.240 |
| LIG_SH2_STAT5 | 252 | 255 | PF00017 | 0.315 |
| LIG_SUMO_SIM_par_1 | 38 | 44 | PF11976 | 0.407 |
| LIG_TYR_ITIM | 238 | 243 | PF00017 | 0.354 |
| MOD_CK1_1 | 213 | 219 | PF00069 | 0.369 |
| MOD_CK2_1 | 206 | 212 | PF00069 | 0.435 |
| MOD_GlcNHglycan | 160 | 163 | PF01048 | 0.240 |
| MOD_GlcNHglycan | 76 | 79 | PF01048 | 0.240 |
| MOD_GlcNHglycan | 86 | 89 | PF01048 | 0.240 |
| MOD_GSK3_1 | 154 | 161 | PF00069 | 0.237 |
| MOD_GSK3_1 | 206 | 213 | PF00069 | 0.434 |
| MOD_GSK3_1 | 43 | 50 | PF00069 | 0.240 |
| MOD_LATS_1 | 138 | 144 | PF00433 | 0.240 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.394 |
| MOD_NEK2_1 | 257 | 262 | PF00069 | 0.449 |
| MOD_NEK2_1 | 83 | 88 | PF00069 | 0.334 |
| MOD_PIKK_1 | 31 | 37 | PF00454 | 0.357 |
| MOD_PKA_2 | 68 | 74 | PF00069 | 0.276 |
| MOD_PKA_2 | 83 | 89 | PF00069 | 0.276 |
| MOD_Plk_4 | 1 | 7 | PF00069 | 0.240 |
| TRG_DiLeu_BaLyEn_6 | 137 | 142 | PF01217 | 0.310 |
| TRG_DiLeu_BaLyEn_6 | 144 | 149 | PF01217 | 0.235 |
| TRG_DiLeu_BaLyEn_6 | 15 | 20 | PF01217 | 0.239 |
| TRG_ENDOCYTIC_2 | 240 | 243 | PF00928 | 0.354 |
| TRG_ENDOCYTIC_2 | 258 | 261 | PF00928 | 0.313 |
| TRG_ENDOCYTIC_2 | 3 | 6 | PF00928 | 0.255 |
| TRG_ENDOCYTIC_2 | 90 | 93 | PF00928 | 0.300 |
| TRG_ER_diArg_1 | 139 | 141 | PF00400 | 0.240 |
| TRG_ER_diArg_1 | 20 | 22 | PF00400 | 0.388 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1HYX9 | Leptomonas seymouri | 84% | 100% |
| A0A0S4KKX1 | Bodo saltans | 67% | 100% |
| A0A1X0P8C1 | Trypanosomatidae | 67% | 100% |
| A0A422P2H6 | Trypanosoma rangeli | 65% | 100% |
| A0QZ12 | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | 32% | 99% |
| A1ADA6 | Escherichia coli O1:K1 / APEC | 27% | 81% |
| A1JPP5 | Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) | 27% | 80% |
| A4HNN0 | Leishmania braziliensis | 84% | 100% |
| A4ICW5 | Leishmania infantum | 100% | 100% |
| A4WAM4 | Enterobacter sp. (strain 638) | 26% | 80% |
| A5GFZ5 | Sus scrofa | 33% | 100% |
| A7ZP72 | Escherichia coli O139:H28 (strain E24377A / ETEC) | 26% | 81% |
| A8A2C1 | Escherichia coli O9:H4 (strain HS) | 27% | 81% |
| A8GDR6 | Serratia proteamaculans (strain 568) | 26% | 80% |
| B1IXT3 | Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) | 27% | 81% |
| B1LLK8 | Escherichia coli (strain SMS-3-5 / SECEC) | 27% | 81% |
| B1X8W7 | Escherichia coli (strain K12 / DH10B) | 27% | 81% |
| B4ETL6 | Proteus mirabilis (strain HI4320) | 26% | 80% |
| B5YX45 | Escherichia coli O157:H7 (strain EC4115 / EHEC) | 27% | 81% |
| B6I7J7 | Escherichia coli (strain SE11) | 27% | 81% |
| B7LAR9 | Escherichia coli (strain 55989 / EAEC) | 27% | 81% |
| B7LM77 | Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73) | 26% | 80% |
| B7M5T6 | Escherichia coli O8 (strain IAI1) | 26% | 81% |
| B7MG21 | Escherichia coli O45:K1 (strain S88 / ExPEC) | 27% | 81% |
| B7MXT5 | Escherichia coli O81 (strain ED1a) | 27% | 81% |
| B7N5L9 | Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) | 27% | 81% |
| B7NNT3 | Escherichia coli O7:K1 (strain IAI39 / ExPEC) | 27% | 81% |
| B7UFR6 | Escherichia coli O127:H6 (strain E2348/69 / EPEC) | 27% | 81% |
| C3KAD3 | Pseudomonas fluorescens (strain SBW25) | 31% | 77% |
| C4ZU96 | Escherichia coli (strain K12 / MC4100 / BW2952) | 27% | 81% |
| C5CBV8 | Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230) | 32% | 100% |
| D0A2I4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 69% | 100% |
| E9ASD9 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 95% | 100% |
| O14466 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 33% | 100% |
| O60762 | Homo sapiens | 33% | 100% |
| O70152 | Mus musculus | 34% | 100% |
| P14020 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 48% | 98% |
| P54856 | Ustilago maydis (strain 521 / FGSC 9021) | 55% | 89% |
| P77757 | Escherichia coli (strain K12) | 27% | 81% |
| Q0T2M9 | Shigella flexneri serotype 5b (strain 8401) | 27% | 81% |
| Q0TFI8 | Escherichia coli O6:K15:H31 (strain 536 / UPEC) | 27% | 81% |
| Q1JQ93 | Bos taurus | 33% | 100% |
| Q1R9G1 | Escherichia coli (strain UTI89 / UPEC) | 27% | 81% |
| Q31YK3 | Shigella boydii serotype 4 (strain Sb227) | 27% | 81% |
| Q32DT4 | Shigella dysenteriae serotype 1 (strain Sd197) | 27% | 81% |
| Q3YZV2 | Shigella sonnei (strain Ss046) | 27% | 81% |
| Q4Q256 | Leishmania major | 96% | 100% |
| Q4ZSZ3 | Pseudomonas syringae pv. syringae (strain B728a) | 29% | 78% |
| Q54LP3 | Dictyostelium discoideum | 31% | 100% |
| Q7UC63 | Shigella flexneri | 27% | 81% |
| Q8FFM2 | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) | 27% | 81% |
| Q8XDZ5 | Escherichia coli O157:H7 | 27% | 81% |
| Q9LM93 | Arabidopsis thaliana | 33% | 100% |
| Q9VIU7 | Drosophila melanogaster | 33% | 100% |
| Q9WU83 | Cricetulus griseus | 33% | 98% |
| V5C000 | Trypanosoma cruzi | 64% | 100% |