LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8IGU3_LEIDO
TriTrypDb:
LdBPK_322180.1 , LdCL_320027200 , LDHU3_32.2700
Length:
91

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGU3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGU3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 32 36 PF00656 0.621
CLV_NRD_NRD_1 24 26 PF00675 0.420
CLV_PCSK_KEX2_1 24 26 PF00082 0.423
DEG_Nend_UBRbox_1 1 4 PF02207 0.275
DOC_PP1_RVXF_1 5 11 PF00149 0.312
LIG_14-3-3_CanoR_1 2 10 PF00244 0.312
LIG_14-3-3_CanoR_1 24 34 PF00244 0.610
LIG_FHA_1 25 31 PF00498 0.663
LIG_FHA_2 30 36 PF00498 0.637
LIG_IBAR_NPY_1 76 78 PF08397 0.615
LIG_Pex14_2 18 22 PF04695 0.388
LIG_SH2_STAT3 78 81 PF00017 0.617
LIG_SH2_STAT5 9 12 PF00017 0.326
LIG_SUMO_SIM_anti_2 13 18 PF11976 0.299
MOD_CK1_1 67 73 PF00069 0.758
MOD_GlcNHglycan 59 62 PF01048 0.517
MOD_GlcNHglycan 85 88 PF01048 0.424
MOD_GSK3_1 25 32 PF00069 0.583
MOD_GSK3_1 63 70 PF00069 0.713
MOD_NEK2_1 1 6 PF00069 0.277
MOD_NEK2_1 10 15 PF00069 0.362
MOD_NEK2_1 64 69 PF00069 0.745
MOD_PIKK_1 25 31 PF00454 0.566
MOD_PKA_1 24 30 PF00069 0.605
MOD_PKA_2 1 7 PF00069 0.275
MOD_PKA_2 23 29 PF00069 0.596
MOD_SUMO_for_1 37 40 PF00179 0.603

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I632 Leptomonas seymouri 73% 100%
A4HKJ5 Leishmania braziliensis 77% 100%
A4I827 Leishmania infantum 100% 100%
E9B2Y5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q571 Leishmania major 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS