Meiotic_recombination_protein_DMC1_putative/GeneD B:LmjF.35.4890

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

meiotic recombination protein DMC1, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IGQ5_LEIDO

TriTrypDb:

LdBPK_354950.1 , LdCL_350054500 , LDHU3_35.6480

Length:

362

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	12
GO:0000228	nuclear chromosome	6	1
GO:0000793	condensed chromosome	6	1
GO:0000794	condensed nuclear chromosome	7	1
GO:0005694	chromosome	5	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3Q8IGQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGQ5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006281	DNA repair	5	11
GO:0006310	DNA recombination	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	11
GO:0006974	DNA damage response	4	11
GO:0007131	reciprocal meiotic recombination	3	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0022402	cell cycle process	2	12
GO:0022414	reproductive process	1	12
GO:0033554	cellular response to stress	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0035825	homologous recombination	6	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	11
GO:0051716	cellular response to stimulus	2	11
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:0140527	reciprocal homologous recombination	7	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1903046	meiotic cell cycle process	2	12
GO:0000730	DNA recombinase assembly	7	1
GO:0006312	mitotic recombination	6	1
GO:0006996	organelle organization	4	1
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0042148	strand invasion	5	1
GO:0043933	protein-containing complex organization	4	1
GO:0051276	chromosome organization	5	1
GO:0065003	protein-containing complex assembly	5	1
GO:0065004	protein-DNA complex assembly	6	1
GO:0070192	chromosome organization involved in meiotic cell cycle	3	1
GO:0071824	protein-DNA complex subunit organization	5	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0090735	DNA repair complex assembly	6	1

Molecular functions
Term	Name	Level	Count
GO:0000150	DNA strand exchange activity	4	12
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140299	small molecule sensor activity	1	12
GO:0140612	DNA damage sensor activity	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:0140664	ATP-dependent DNA damage sensor activity	3	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0003690	double-stranded DNA binding	5	1
GO:0003697	single-stranded DNA binding	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	207	211	PF00656	0.448
CLV_MEL_PAP_1	197	203	PF00089	0.215
CLV_NRD_NRD_1	101	103	PF00675	0.348
CLV_NRD_NRD_1	325	327	PF00675	0.204
CLV_NRD_NRD_1	78	80	PF00675	0.228
CLV_PCSK_KEX2_1	101	103	PF00082	0.490
CLV_PCSK_SKI1_1	143	147	PF00082	0.310
CLV_PCSK_SKI1_1	267	271	PF00082	0.215
DEG_APCC_DBOX_1	78	86	PF00400	0.428
DOC_MAPK_gen_1	101	108	PF00069	0.513
DOC_MAPK_gen_1	79	85	PF00069	0.471
DOC_PP1_RVXF_1	250	256	PF00149	0.411
DOC_PP4_FxxP_1	25	28	PF00568	0.564
DOC_PP4_FxxP_1	338	341	PF00568	0.508
DOC_PP4_FxxP_1	69	72	PF00568	0.502
DOC_USP7_MATH_1	316	320	PF00917	0.404
DOC_WW_Pin1_4	337	342	PF00397	0.404
LIG_14-3-3_CanoR_1	101	109	PF00244	0.320
LIG_14-3-3_CanoR_1	123	131	PF00244	0.410
LIG_14-3-3_CanoR_1	143	152	PF00244	0.319
LIG_14-3-3_CanoR_1	153	163	PF00244	0.374
LIG_14-3-3_CanoR_1	322	326	PF00244	0.404
LIG_BRCT_BRCA1_1	9	13	PF00533	0.590
LIG_Clathr_ClatBox_1	241	245	PF01394	0.404
LIG_Clathr_ClatBox_1	250	254	PF01394	0.404
LIG_Clathr_ClatBox_1	44	48	PF01394	0.486
LIG_CtBP_PxDLS_1	170	174	PF00389	0.446
LIG_FHA_1	124	130	PF00498	0.469
LIG_FHA_1	160	166	PF00498	0.411
LIG_FHA_1	287	293	PF00498	0.404
LIG_FHA_1	318	324	PF00498	0.404
LIG_GBD_Chelix_1	268	276	PF00786	0.192
LIG_Integrin_RGD_1	329	331	PF01839	0.215
LIG_LIR_Gen_1	236	247	PF02991	0.472
LIG_LIR_LC3C_4	240	244	PF02991	0.446
LIG_LIR_Nem_3	146	152	PF02991	0.412
LIG_LIR_Nem_3	236	242	PF02991	0.441
LIG_MYND_3	343	347	PF01753	0.448
LIG_NRBOX	130	136	PF00104	0.404
LIG_PCNA_yPIPBox_3	258	272	PF02747	0.404
LIG_Pex14_2	251	255	PF04695	0.404
LIG_SH2_STAT5	182	185	PF00017	0.404
LIG_SH2_STAT5	218	221	PF00017	0.422
LIG_SH2_STAT5	287	290	PF00017	0.410
LIG_SH3_3	290	296	PF00018	0.404
LIG_SH3_3	300	306	PF00018	0.404
LIG_SH3_3	338	344	PF00018	0.440
LIG_SUMO_SIM_anti_2	240	246	PF11976	0.446
LIG_SUMO_SIM_par_1	240	246	PF11976	0.404
LIG_SUMO_SIM_par_1	43	48	PF11976	0.468
LIG_UBA3_1	226	233	PF00899	0.238
LIG_UBA3_1	271	277	PF00899	0.238
LIG_UBA3_1	82	86	PF00899	0.260
MOD_CK1_1	125	131	PF00069	0.357
MOD_CK2_1	141	147	PF00069	0.253
MOD_CK2_1	339	345	PF00069	0.261
MOD_CK2_1	348	354	PF00069	0.307
MOD_GlcNHglycan	254	258	PF01048	0.256
MOD_GSK3_1	139	146	PF00069	0.398
MOD_GSK3_1	159	166	PF00069	0.262
MOD_GSK3_1	317	324	PF00069	0.238
MOD_NEK2_1	122	127	PF00069	0.463
MOD_NEK2_1	163	168	PF00069	0.241
MOD_NEK2_1	31	36	PF00069	0.583
MOD_NEK2_2	297	302	PF00069	0.238
MOD_PIKK_1	154	160	PF00454	0.238
MOD_PIKK_1	270	276	PF00454	0.383
MOD_PKA_1	101	107	PF00069	0.446
MOD_PKA_2	101	107	PF00069	0.560
MOD_PKA_2	117	123	PF00069	0.183
MOD_PKA_2	321	327	PF00069	0.238
MOD_Plk_2-3	141	147	PF00069	0.253
MOD_Plk_2-3	204	210	PF00069	0.300
MOD_Plk_2-3	339	345	PF00069	0.242
MOD_Plk_4	117	123	PF00069	0.280
MOD_Plk_4	204	210	PF00069	0.412
MOD_Plk_4	225	231	PF00069	0.259
MOD_Plk_4	297	303	PF00069	0.244
MOD_ProDKin_1	337	343	PF00069	0.238
MOD_SUMO_rev_2	300	309	PF00179	0.273
MOD_SUMO_rev_2	89	93	PF00179	0.238
TRG_DiLeu_BaLyEn_6	40	45	PF01217	0.515
TRG_ER_diArg_1	101	103	PF00400	0.481
TRG_ER_diArg_1	193	196	PF00400	0.383
TRG_NES_CRM1_1	192	204	PF08389	0.253
TRG_NES_CRM1_1	266	281	PF08389	0.221
TRG_NLS_MonoExtC_3	325	331	PF00514	0.238
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.383
TRG_Pf-PMV_PEXEL_1	195	199	PF00026	0.383
TRG_Pf-PMV_PEXEL_1	86	90	PF00026	0.272

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P957	Leptomonas seymouri	93%	100%
A0A0N1IA48	Leptomonas seymouri	50%	96%
A0A0S4J9C6	Bodo saltans	75%	100%
A0A0S4JEJ8	Bodo saltans	52%	100%
A0A1X0NV67	Trypanosomatidae	27%	91%
A0A1X0NYJ1	Trypanosomatidae	50%	96%
A0A1X0P517	Trypanosomatidae	81%	100%
A0A3Q8ID02	Leishmania donovani	52%	100%
A0A3R7M9F0	Trypanosoma rangeli	79%	100%
A0A422P1N0	Trypanosoma rangeli	50%	100%
A0JUY4	Arthrobacter sp. (strain FB24)	26%	100%
A1R548	Paenarthrobacter aurescens (strain TC1)	27%	100%
A2SR54	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	39%	100%
A3CWU4	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	41%	100%
A3MXX9	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	46%	100%
A3PLJ2	Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)	29%	100%
A4FWV5	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	43%	100%
A4HG95	Leishmania braziliensis	50%	100%
A4HNF3	Leishmania braziliensis	95%	100%
A4I3C9	Leishmania infantum	52%	100%
A4IC25	Leishmania infantum	100%	100%
A4WN87	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	46%	100%
A4WV48	Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)	28%	100%
A4YCN4	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	45%	100%
A5ICV8	Legionella pneumophila (strain Corby)	30%	100%
A5IL83	Thermotoga petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1)	30%	100%
A5UMW0	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	43%	100%
A6VGG2	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	42%	100%
A8AB83	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	44%	100%
A9AA90	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	42%	100%
A9M5L8	Brucella canis (strain ATCC 23365 / NCTC 10854)	30%	100%
B0CH00	Brucella suis (strain ATCC 23445 / NCTC 10510)	30%	100%
B0R7Y4	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	37%	100%
B0TW17	Francisella philomiragia subsp. philomiragia (strain ATCC 25017 / FSC 153 / O#319-036)	26%	100%
B1I8Q1	Streptococcus pneumoniae (strain Hungary19A-6)	28%	93%
B1LAG3	Thermotoga sp. (strain RQ2)	30%	100%
B1LWT6	Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)	29%	100%
B1YC14	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	47%	100%
B1YMB9	Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 / 255-15)	28%	100%
B2IM28	Streptococcus pneumoniae (strain CGSP14)	28%	93%
B2RZJ7	Borrelia hermsii (strain HS1 / DAH)	27%	100%
B2S648	Brucella abortus (strain S19)	30%	100%
B5E2E0	Streptococcus pneumoniae serotype 19F (strain G54)	28%	93%
B7J164	Borreliella burgdorferi (strain ZS7)	28%	99%
B8BM09	Oryza sativa subsp. indica	67%	100%
B8D610	Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)	45%	100%
B8HG89	Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6)	26%	100%
B8ZNU7	Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)	28%	93%
B9K7N7	Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)	31%	100%
B9KHJ1	Anaplasma marginale (strain Florida)	27%	100%
C0RJG9	Brucella melitensis biotype 2 (strain ATCC 23457)	30%	100%
C1C9K8	Streptococcus pneumoniae (strain 70585)	28%	93%
C1CGM4	Streptococcus pneumoniae (strain JJA)	28%	93%
C1CMP5	Streptococcus pneumoniae (strain P1031)	28%	93%
C1CTH6	Streptococcus pneumoniae (strain Taiwan19F-14)	28%	93%
C3MRI1	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	45%	100%
C3MY77	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	45%	100%
C3MZK6	Sulfolobus islandicus (strain M.16.27)	45%	100%
C3N7M8	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	45%	100%
C3NFU5	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	45%	100%
C4KIT6	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	45%	100%
C9ZYH4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
E9AZL6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
E9B717	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
O15315	Homo sapiens	30%	94%
O27436	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	44%	100%
O29269	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	45%	100%
O35719	Mus musculus	30%	100%
O42634	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
O43502	Homo sapiens	31%	96%
O43542	Homo sapiens	27%	100%
O61127	Leishmania major	51%	100%
O61128	Leishmania major	98%	100%
O73948	Methanococcus voltae	44%	100%
O74036	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	49%	100%
O77507	Oryctolagus cuniculus	56%	100%
O93748	Cenarchaeum symbiosum (strain A)	45%	91%
P0A451	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	28%	93%
P0A452	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	28%	93%
P0CW58	Methanococcus maripaludis	42%	100%
P0CW59	Methanococcus maripaludis (strain S2 / LL)	42%	100%
P0CW91	Aeropyrum pernix	44%	100%
P0CW92	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	45%	100%
P0DN85	Brucella abortus biovar 1 (strain 9-941)	30%	100%
P25453	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	55%	100%
P25454	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	90%
P36203	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	30%	100%
P36601	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	55%	99%
P37383	Gallus gallus	57%	100%
P37384	Lilium longiflorum	67%	100%
P42441	Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)	29%	100%
P49985	Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)	26%	91%
P50265	Candida albicans	56%	100%
P58254	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	28%	100%
P65975	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	30%	100%
P65976	Brucella suis biovar 1 (strain 1330)	30%	100%
P65981	Tropheryma whipplei (strain Twist)	28%	83%
P65982	Tropheryma whipplei (strain TW08/27)	28%	83%
P70099	Cricetulus griseus	56%	100%
P94102	Arabidopsis thaliana	55%	100%
P95846	Streptomyces rimosus	28%	96%
Q04BJ8	Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365 / Lb-18)	29%	98%
Q04IM6	Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)	28%	93%
Q05358	Legionella pneumophila	30%	100%
Q06609	Homo sapiens	57%	100%
Q08297	Mus musculus	56%	100%
Q08DH8	Bos taurus	30%	100%
Q12UG7	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	43%	100%
Q14565	Homo sapiens	61%	100%
Q18EU1	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	40%	100%
Q1LTQ3	Baumannia cicadellinicola subsp. Homalodisca coagulata	29%	100%
Q27297	Drosophila melanogaster	50%	100%
Q2KJ94	Bos taurus	56%	100%
Q2NE95	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	44%	100%
Q2RQH9	Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)	28%	99%
Q2YRU7	Brucella abortus (strain 2308)	30%	100%
Q31F89	Hydrogenovibrio crunogenus (strain DSM 25203 / XCL-2)	30%	100%
Q39009	Arabidopsis thaliana	64%	100%
Q40134	Solanum lycopersicum	56%	100%
Q46A31	Methanosarcina barkeri (strain Fusaro / DSM 804)	42%	100%
Q48328	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	39%	100%
Q49593	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	44%	100%
Q4JAT5	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	44%	100%
Q54PJ7	Dictyostelium discoideum	31%	95%
Q55075	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	45%	100%
Q59180	Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)	28%	99%
Q5PBT6	Anaplasma marginale (strain St. Maries)	27%	100%
Q5WVQ0	Legionella pneumophila (strain Lens)	30%	100%
Q5X4B5	Legionella pneumophila (strain Paris)	30%	100%
Q5YT00	Nocardia farcinica (strain IFM 10152)	29%	100%
Q5ZUJ7	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	30%	100%
Q61880	Mus musculus	61%	100%
Q67EU8	Zea mays	55%	100%
Q6L126	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	44%	100%
Q74MX9	Nanoarchaeum equitans (strain Kin4-M)	45%	100%
Q7EAG4	Oryza sativa subsp. indica	67%	100%
Q7GBF7	Oryza sativa subsp. japonica	67%	100%
Q7GBF8	Oryza sativa subsp. japonica	67%	100%
Q7NXL9	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	28%	100%
Q895I5	Clostridium tetani (strain Massachusetts / E88)	29%	100%
Q8GXF0	Arabidopsis thaliana	34%	100%
Q8MKI8	Canis lupus familiaris	56%	100%
Q8PZN5	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	42%	100%
Q8R2J9	Cricetulus griseus	29%	99%
Q8TK71	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	43%	100%
Q8VS69	Borrelia hermsii	27%	100%
Q8ZYR9	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	47%	100%
Q91917	Xenopus laevis	57%	100%
Q91918	Xenopus laevis	57%	100%
Q924H5	Mus musculus	30%	99%
Q96449	Glycine max	65%	100%
Q975Y1	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	44%	100%
Q97BJ9	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	44%	100%
Q99133	Ustilago maydis (strain 521 / FGSC 9021)	54%	100%
Q9CXE6	Mus musculus	30%	100%
Q9HJ68	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	44%	100%
Q9HMM4	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	37%	100%
Q9SK02	Arabidopsis thaliana	30%	98%
Q9UUL2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
Q9UWR5	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	47%	100%
Q9V233	Pyrococcus abyssi (strain GE5 / Orsay)	49%	100%
Q9XED7	Zea mays	58%	100%
Q9Y8J4	Desulfurococcus amylolyticus	45%	100%
V5B714	Trypanosoma cruzi	79%	100%
V5BKV4	Trypanosoma cruzi	51%	98%