LeishMANIAdb
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AN1-like_Zinc_finger_containing_protein_putative/ Pfam:PF01428

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
AN1-like_Zinc_finger_containing_protein_putative/ Pfam:PF01428
Gene product:
AN1-like zinc finger, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IGQ3_LEIDO
TriTrypDb:
LdBPK_281280.1 , LdCL_280017400 , LDHU3_28.1610
Length:
100

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGQ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGQ3

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005488 binding 1 8
GO:0008270 zinc ion binding 6 8
GO:0043167 ion binding 2 8
GO:0043169 cation binding 3 8
GO:0046872 metal ion binding 4 8
GO:0046914 transition metal ion binding 5 8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 60 62 PF00675 0.553
CLV_NRD_NRD_1 63 65 PF00675 0.576
CLV_NRD_NRD_1 86 88 PF00675 0.553
CLV_PCSK_FUR_1 61 65 PF00082 0.630
CLV_PCSK_KEX2_1 60 62 PF00082 0.572
CLV_PCSK_KEX2_1 63 65 PF00082 0.591
CLV_PCSK_KEX2_1 73 75 PF00082 0.489
CLV_PCSK_KEX2_1 86 88 PF00082 0.498
CLV_PCSK_PC1ET2_1 73 75 PF00082 0.515
CLV_PCSK_SKI1_1 50 54 PF00082 0.477
DOC_USP7_UBL2_3 73 77 PF12436 0.461
LIG_14-3-3_CanoR_1 27 35 PF00244 0.321
LIG_BIR_II_1 1 5 PF00653 0.548
LIG_SH2_STAT5 28 31 PF00017 0.471
LIG_SH3_3 13 19 PF00018 0.356
MOD_PKA_1 87 93 PF00069 0.558
MOD_SUMO_for_1 19 22 PF00179 0.356
MOD_SUMO_rev_2 70 79 PF00179 0.568
TRG_ER_diArg_1 60 63 PF00400 0.621
TRG_NLS_Bipartite_1 72 92 PF00514 0.536
TRG_NLS_MonoExtC_3 86 91 PF00514 0.627
TRG_NLS_MonoExtN_4 86 92 PF00514 0.574
TRG_Pf-PMV_PEXEL_1 64 69 PF00026 0.631

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCY9 Leptomonas seymouri 80% 100%
A0A0S4KJP3 Bodo saltans 37% 100%
A0A1X0NYL9 Trypanosomatidae 62% 68%
A4HGG4 Leishmania braziliensis 88% 100%
A4I3J6 Leishmania infantum 100% 100%
E9AZT6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q4Q8E9 Leishmania major 95% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS