DNA mismatch repair protein MSH2, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA mismatch repair protein MSH2, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IGP6_LEIDO

TriTrypDb:

LdBPK_330420.1 , LdCL_330009600 , LDHU3_33.0630

Length:

939

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0032300	mismatch repair complex	2	12
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:0005737	cytoplasm	2	1
GO:0032301	MutSalpha complex	3	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

A0A3Q8IGP6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGP6

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006281	DNA repair	5	12
GO:0006298	mismatch repair	6	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	12
GO:0006974	DNA damage response	4	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0033554	cellular response to stress	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	12
GO:0051716	cellular response to stimulus	2	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006310	DNA recombination	5	1
GO:0006312	mitotic recombination	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003690	double-stranded DNA binding	5	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0030983	mismatched DNA binding	6	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140299	small molecule sensor activity	1	12
GO:0140612	DNA damage sensor activity	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:0140664	ATP-dependent DNA damage sensor activity	3	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.423
CLV_C14_Caspase3-7	3	7	PF00656	0.536
CLV_C14_Caspase3-7	545	549	PF00656	0.450
CLV_MEL_PAP_1	725	731	PF00089	0.250
CLV_NRD_NRD_1	217	219	PF00675	0.480
CLV_NRD_NRD_1	289	291	PF00675	0.562
CLV_NRD_NRD_1	295	297	PF00675	0.522
CLV_NRD_NRD_1	395	397	PF00675	0.271
CLV_NRD_NRD_1	400	402	PF00675	0.280
CLV_NRD_NRD_1	527	529	PF00675	0.250
CLV_NRD_NRD_1	565	567	PF00675	0.279
CLV_NRD_NRD_1	579	581	PF00675	0.261
CLV_NRD_NRD_1	89	91	PF00675	0.450
CLV_NRD_NRD_1	892	894	PF00675	0.586
CLV_PCSK_KEX2_1	217	219	PF00082	0.480
CLV_PCSK_KEX2_1	289	291	PF00082	0.562
CLV_PCSK_KEX2_1	295	297	PF00082	0.522
CLV_PCSK_KEX2_1	386	388	PF00082	0.257
CLV_PCSK_KEX2_1	400	402	PF00082	0.229
CLV_PCSK_KEX2_1	565	567	PF00082	0.336
CLV_PCSK_KEX2_1	579	581	PF00082	0.336
CLV_PCSK_KEX2_1	654	656	PF00082	0.503
CLV_PCSK_KEX2_1	89	91	PF00082	0.449
CLV_PCSK_KEX2_1	900	902	PF00082	0.501
CLV_PCSK_PC1ET2_1	386	388	PF00082	0.336
CLV_PCSK_PC1ET2_1	579	581	PF00082	0.355
CLV_PCSK_PC1ET2_1	654	656	PF00082	0.316
CLV_PCSK_PC1ET2_1	900	902	PF00082	0.501
CLV_PCSK_PC7_1	396	402	PF00082	0.261
CLV_PCSK_SKI1_1	162	166	PF00082	0.291
CLV_PCSK_SKI1_1	188	192	PF00082	0.409
CLV_PCSK_SKI1_1	289	293	PF00082	0.557
CLV_PCSK_SKI1_1	377	381	PF00082	0.274
CLV_PCSK_SKI1_1	434	438	PF00082	0.336
CLV_PCSK_SKI1_1	510	514	PF00082	0.274
CLV_Separin_Metazoa	253	257	PF03568	0.510
DEG_APCC_DBOX_1	656	664	PF00400	0.382
DEG_APCC_DBOX_1	931	939	PF00400	0.589
DOC_CYCLIN_RxL_1	159	170	PF00134	0.522
DOC_CYCLIN_RxL_1	396	408	PF00134	0.536
DOC_CYCLIN_yClb5_NLxxxL_5	182	191	PF00134	0.410
DOC_MAPK_gen_1	396	405	PF00069	0.450
DOC_MAPK_gen_1	535	543	PF00069	0.453
DOC_MAPK_gen_1	654	663	PF00069	0.516
DOC_MAPK_gen_1	790	797	PF00069	0.490
DOC_MAPK_HePTP_8	651	663	PF00069	0.511
DOC_MAPK_MEF2A_6	222	229	PF00069	0.508
DOC_MAPK_MEF2A_6	363	371	PF00069	0.461
DOC_MAPK_MEF2A_6	654	663	PF00069	0.516
DOC_MAPK_MEF2A_6	697	705	PF00069	0.450
DOC_PP1_RVXF_1	160	167	PF00149	0.468
DOC_PP2B_LxvP_1	255	258	PF13499	0.391
DOC_USP7_MATH_1	102	106	PF00917	0.520
DOC_USP7_MATH_1	136	140	PF00917	0.462
DOC_USP7_MATH_1	18	22	PF00917	0.455
DOC_USP7_MATH_1	197	201	PF00917	0.677
DOC_USP7_MATH_1	878	882	PF00917	0.688
DOC_USP7_MATH_2	258	264	PF00917	0.472
DOC_USP7_UBL2_3	47	51	PF12436	0.483
DOC_WW_Pin1_4	110	115	PF00397	0.393
DOC_WW_Pin1_4	169	174	PF00397	0.476
DOC_WW_Pin1_4	193	198	PF00397	0.577
LIG_14-3-3_CanoR_1	162	167	PF00244	0.377
LIG_14-3-3_CanoR_1	212	219	PF00244	0.490
LIG_14-3-3_CanoR_1	261	265	PF00244	0.469
LIG_14-3-3_CanoR_1	295	299	PF00244	0.468
LIG_14-3-3_CanoR_1	363	367	PF00244	0.450
LIG_14-3-3_CanoR_1	400	404	PF00244	0.503
LIG_14-3-3_CanoR_1	532	541	PF00244	0.531
LIG_14-3-3_CanoR_1	551	560	PF00244	0.343
LIG_14-3-3_CanoR_1	769	775	PF00244	0.450
LIG_14-3-3_CanoR_1	790	796	PF00244	0.536
LIG_14-3-3_CanoR_1	831	837	PF00244	0.461
LIG_14-3-3_CanoR_1	89	95	PF00244	0.400
LIG_14-3-3_CanoR_1	893	902	PF00244	0.512
LIG_Actin_WH2_2	391	408	PF00022	0.510
LIG_Actin_WH2_2	519	537	PF00022	0.536
LIG_Actin_WH2_2	75	91	PF00022	0.393
LIG_Actin_WH2_2	816	833	PF00022	0.461
LIG_APCC_ABBA_1	367	372	PF00400	0.536
LIG_BIR_III_2	646	650	PF00653	0.521
LIG_BRCT_BRCA1_1	138	142	PF00533	0.491
LIG_BRCT_BRCA1_1	20	24	PF00533	0.498
LIG_BRCT_BRCA1_1	797	801	PF00533	0.444
LIG_CaM_IQ_9	232	248	PF13499	0.547
LIG_CaM_IQ_9	379	395	PF13499	0.453
LIG_Clathr_ClatBox_1	124	128	PF01394	0.470
LIG_CtBP_PxDLS_1	686	692	PF00389	0.450
LIG_deltaCOP1_diTrp_1	869	873	PF00928	0.586
LIG_FHA_1	170	176	PF00498	0.369
LIG_FHA_1	379	385	PF00498	0.512
LIG_FHA_1	51	57	PF00498	0.414
LIG_FHA_1	535	541	PF00498	0.561
LIG_FHA_1	600	606	PF00498	0.536
LIG_FHA_1	629	635	PF00498	0.679
LIG_FHA_1	677	683	PF00498	0.418
LIG_FHA_1	730	736	PF00498	0.450
LIG_FHA_1	739	745	PF00498	0.450
LIG_FHA_1	758	764	PF00498	0.450
LIG_FHA_2	116	122	PF00498	0.455
LIG_FHA_2	163	169	PF00498	0.355
LIG_FHA_2	174	180	PF00498	0.417
LIG_FHA_2	204	210	PF00498	0.594
LIG_FHA_2	363	369	PF00498	0.510
LIG_FHA_2	454	460	PF00498	0.498
LIG_FHA_2	543	549	PF00498	0.485
LIG_GBD_Chelix_1	582	590	PF00786	0.355
LIG_LIR_Apic_2	427	431	PF02991	0.519
LIG_LIR_Apic_2	438	443	PF02991	0.416
LIG_LIR_Gen_1	300	310	PF02991	0.372
LIG_LIR_Gen_1	408	419	PF02991	0.512
LIG_LIR_Gen_1	798	808	PF02991	0.450
LIG_LIR_Gen_1	869	878	PF02991	0.595
LIG_LIR_Nem_3	165	169	PF02991	0.355
LIG_LIR_Nem_3	21	27	PF02991	0.481
LIG_LIR_Nem_3	300	305	PF02991	0.389
LIG_LIR_Nem_3	328	334	PF02991	0.450
LIG_LIR_Nem_3	408	414	PF02991	0.512
LIG_LIR_Nem_3	495	501	PF02991	0.536
LIG_LIR_Nem_3	519	523	PF02991	0.452
LIG_LIR_Nem_3	561	567	PF02991	0.474
LIG_LIR_Nem_3	588	592	PF02991	0.450
LIG_LIR_Nem_3	652	656	PF02991	0.490
LIG_LIR_Nem_3	771	777	PF02991	0.450
LIG_LIR_Nem_3	798	804	PF02991	0.536
LIG_LIR_Nem_3	844	848	PF02991	0.450
LIG_LIR_Nem_3	869	873	PF02991	0.572
LIG_NRBOX	186	192	PF00104	0.406
LIG_PCNA_yPIPBox_3	373	387	PF02747	0.536
LIG_PDZ_Class_3	934	939	PF00595	0.581
LIG_Pex14_2	777	781	PF04695	0.450
LIG_Pex14_2	797	801	PF04695	0.319
LIG_PTB_Apo_2	813	820	PF02174	0.450
LIG_SH2_CRK	428	432	PF00017	0.555
LIG_SH2_CRK	498	502	PF00017	0.499
LIG_SH2_CRK	520	524	PF00017	0.450
LIG_SH2_CRK	564	568	PF00017	0.474
LIG_SH2_PTP2	440	443	PF00017	0.458
LIG_SH2_SRC	589	592	PF00017	0.474
LIG_SH2_STAP1	898	902	PF00017	0.442
LIG_SH2_STAT3	834	837	PF00017	0.492
LIG_SH2_STAT5	106	109	PF00017	0.436
LIG_SH2_STAT5	169	172	PF00017	0.419
LIG_SH2_STAT5	293	296	PF00017	0.406
LIG_SH2_STAT5	36	39	PF00017	0.355
LIG_SH2_STAT5	428	431	PF00017	0.499
LIG_SH2_STAT5	440	443	PF00017	0.405
LIG_SH2_STAT5	49	52	PF00017	0.342
LIG_SH2_STAT5	522	525	PF00017	0.450
LIG_SH2_STAT5	589	592	PF00017	0.450
LIG_SH2_STAT5	834	837	PF00017	0.522
LIG_SH2_STAT5	848	851	PF00017	0.390
LIG_SH2_STAT5	934	937	PF00017	0.612
LIG_SH3_3	191	197	PF00018	0.529
LIG_SH3_3	280	286	PF00018	0.551
LIG_SH3_3	368	374	PF00018	0.461
LIG_SUMO_SIM_anti_2	631	636	PF11976	0.727
LIG_SUMO_SIM_anti_2	70	76	PF11976	0.400
LIG_SUMO_SIM_anti_2	759	766	PF11976	0.449
LIG_SUMO_SIM_par_1	539	546	PF11976	0.474
LIG_SUMO_SIM_par_1	70	76	PF11976	0.411
LIG_SUMO_SIM_par_1	759	766	PF11976	0.490
LIG_TRFH_1	834	838	PF08558	0.450
LIG_Vh1_VBS_1	746	764	PF01044	0.510
LIG_WRC_WIRS_1	650	655	PF05994	0.490
LIG_WRC_WIRS_1	739	744	PF05994	0.450
MOD_CK1_1	228	234	PF00069	0.552
MOD_CK1_1	28	34	PF00069	0.442
MOD_CK1_1	329	335	PF00069	0.471
MOD_CK1_1	61	67	PF00069	0.598
MOD_CK1_1	751	757	PF00069	0.516
MOD_CK1_1	826	832	PF00069	0.499
MOD_CK1_1	879	885	PF00069	0.561
MOD_CK2_1	115	121	PF00069	0.441
MOD_CK2_1	162	168	PF00069	0.382
MOD_CK2_1	228	234	PF00069	0.476
MOD_CK2_1	362	368	PF00069	0.461
MOD_CK2_1	453	459	PF00069	0.520
MOD_CK2_1	524	530	PF00069	0.467
MOD_CK2_1	533	539	PF00069	0.451
MOD_GlcNHglycan	136	139	PF01048	0.446
MOD_GlcNHglycan	199	202	PF01048	0.613
MOD_GlcNHglycan	306	309	PF01048	0.467
MOD_GlcNHglycan	60	63	PF01048	0.511
MOD_GlcNHglycan	640	643	PF01048	0.673
MOD_GlcNHglycan	65	68	PF01048	0.555
MOD_GlcNHglycan	748	751	PF01048	0.250
MOD_GlcNHglycan	811	814	PF01048	0.344
MOD_GlcNHglycan	824	828	PF01048	0.281
MOD_GlcNHglycan	881	884	PF01048	0.683
MOD_GlcNHglycan	895	898	PF01048	0.375
MOD_GSK3_1	169	176	PF00069	0.479
MOD_GSK3_1	193	200	PF00069	0.563
MOD_GSK3_1	294	301	PF00069	0.421
MOD_GSK3_1	322	329	PF00069	0.461
MOD_GSK3_1	426	433	PF00069	0.504
MOD_GSK3_1	458	465	PF00069	0.452
MOD_GSK3_1	539	546	PF00069	0.459
MOD_GSK3_1	57	64	PF00069	0.541
MOD_GSK3_1	691	698	PF00069	0.450
MOD_GSK3_1	791	798	PF00069	0.515
MOD_GSK3_1	826	833	PF00069	0.474
MOD_GSK3_1	98	105	PF00069	0.555
MOD_N-GLC_1	115	120	PF02516	0.457
MOD_N-GLC_1	157	162	PF02516	0.384
MOD_N-GLC_1	62	67	PF02516	0.452
MOD_N-GLC_2	335	337	PF02516	0.250
MOD_NEK2_1	120	125	PF00069	0.440
MOD_NEK2_1	134	139	PF00069	0.369
MOD_NEK2_1	157	162	PF00069	0.384
MOD_NEK2_1	294	299	PF00069	0.453
MOD_NEK2_1	379	384	PF00069	0.502
MOD_NEK2_1	405	410	PF00069	0.478
MOD_NEK2_1	487	492	PF00069	0.536
MOD_NEK2_1	524	529	PF00069	0.461
MOD_NEK2_1	582	587	PF00069	0.452
MOD_NEK2_1	673	678	PF00069	0.460
MOD_NEK2_1	682	687	PF00069	0.424
MOD_NEK2_1	746	751	PF00069	0.450
MOD_NEK2_1	795	800	PF00069	0.452
MOD_NEK2_1	830	835	PF00069	0.447
MOD_NEK2_2	649	654	PF00069	0.520
MOD_PIKK_1	142	148	PF00454	0.439
MOD_PIKK_1	18	24	PF00454	0.434
MOD_PIKK_1	379	385	PF00454	0.428
MOD_PIKK_1	405	411	PF00454	0.536
MOD_PIKK_1	487	493	PF00454	0.555
MOD_PIKK_1	674	680	PF00454	0.369
MOD_PIKK_1	754	760	PF00454	0.498
MOD_PIKK_1	802	808	PF00454	0.461
MOD_PK_1	90	96	PF00069	0.389
MOD_PKA_1	565	571	PF00069	0.555
MOD_PKA_1	57	63	PF00069	0.496
MOD_PKA_1	893	899	PF00069	0.574
MOD_PKA_2	211	217	PF00069	0.548
MOD_PKA_2	260	266	PF00069	0.474
MOD_PKA_2	28	34	PF00069	0.480
MOD_PKA_2	294	300	PF00069	0.466
MOD_PKA_2	322	328	PF00069	0.461
MOD_PKA_2	362	368	PF00069	0.450
MOD_PKA_2	399	405	PF00069	0.461
MOD_PKA_2	524	530	PF00069	0.455
MOD_PKA_2	534	540	PF00069	0.440
MOD_PKA_2	565	571	PF00069	0.536
MOD_PKA_2	768	774	PF00069	0.462
MOD_PKA_2	791	797	PF00069	0.533
MOD_PKA_2	830	836	PF00069	0.461
MOD_PKA_2	98	104	PF00069	0.501
MOD_Plk_1	120	126	PF00069	0.449
MOD_Plk_1	157	163	PF00069	0.370
MOD_Plk_1	203	209	PF00069	0.650
MOD_Plk_1	458	464	PF00069	0.467
MOD_Plk_1	802	808	PF00069	0.461
MOD_Plk_2-3	260	266	PF00069	0.474
MOD_Plk_2-3	869	875	PF00069	0.561
MOD_Plk_4	102	108	PF00069	0.590
MOD_Plk_4	120	126	PF00069	0.340
MOD_Plk_4	136	142	PF00069	0.300
MOD_Plk_4	298	304	PF00069	0.396
MOD_Plk_4	326	332	PF00069	0.450
MOD_Plk_4	362	368	PF00069	0.450
MOD_Plk_4	40	46	PF00069	0.427
MOD_Plk_4	453	459	PF00069	0.555
MOD_Plk_4	585	591	PF00069	0.458
MOD_Plk_4	691	697	PF00069	0.450
MOD_Plk_4	738	744	PF00069	0.450
MOD_Plk_4	748	754	PF00069	0.450
MOD_Plk_4	791	797	PF00069	0.510
MOD_Plk_4	855	861	PF00069	0.524
MOD_ProDKin_1	110	116	PF00069	0.393
MOD_ProDKin_1	169	175	PF00069	0.470
MOD_ProDKin_1	193	199	PF00069	0.591
MOD_SUMO_for_1	436	439	PF00179	0.536
MOD_SUMO_for_1	512	515	PF00179	0.450
MOD_SUMO_for_1	635	638	PF00179	0.706
MOD_SUMO_for_1	921	924	PF00179	0.538
MOD_SUMO_rev_2	594	599	PF00179	0.450
TRG_DiLeu_BaEn_1	311	316	PF01217	0.536
TRG_DiLeu_BaEn_4	259	265	PF01217	0.490
TRG_ENDOCYTIC_2	302	305	PF00928	0.473
TRG_ENDOCYTIC_2	498	501	PF00928	0.536
TRG_ENDOCYTIC_2	520	523	PF00928	0.450
TRG_ENDOCYTIC_2	564	567	PF00928	0.474
TRG_ENDOCYTIC_2	589	592	PF00928	0.450
TRG_ENDOCYTIC_2	774	777	PF00928	0.450
TRG_ER_diArg_1	216	218	PF00400	0.478
TRG_ER_diArg_1	294	296	PF00400	0.525
TRG_ER_diArg_1	564	566	PF00400	0.536
TRG_ER_diArg_1	789	792	PF00400	0.527
TRG_ER_diArg_1	88	90	PF00400	0.447
TRG_NES_CRM1_1	358	372	PF08389	0.461
TRG_NES_CRM1_1	733	748	PF08389	0.450
TRG_NLS_Bipartite_1	565	583	PF00514	0.536
TRG_NLS_MonoExtC_3	578	584	PF00514	0.510
TRG_Pf-PMV_PEXEL_1	217	221	PF00026	0.409
TRG_Pf-PMV_PEXEL_1	230	234	PF00026	0.463
TRG_Pf-PMV_PEXEL_1	455	459	PF00026	0.290
TRG_Pf-PMV_PEXEL_1	565	569	PF00026	0.330
TRG_Pf-PMV_PEXEL_1	580	584	PF00026	0.348
TRG_Pf-PMV_PEXEL_1	903	907	PF00026	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6N3	Leptomonas seymouri	80%	99%
A0A0S4J224	Bodo saltans	50%	100%
A0A1X0P1A3	Trypanosomatidae	59%	98%
A0A3R7KEP9	Trypanosoma rangeli	59%	98%
A1R0M2	Borrelia turicatae (strain 91E135)	29%	100%
A4HL76	Leishmania braziliensis	88%	100%
A4I8Q5	Leishmania infantum	100%	100%
A6LLR1	Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429)	26%	100%
A7HMG4	Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)	28%	100%
A9NGL6	Acholeplasma laidlawii (strain PG-8A)	27%	100%
A9WFZ9	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)	31%	97%
B0B918	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)	27%	100%
B0BAP7	Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)	27%	100%
B0VAU7	Acinetobacter baumannii (strain AYE)	29%	100%
B2HX50	Acinetobacter baumannii (strain ACICU)	29%	100%
B3E6P2	Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)	31%	100%
B3EEE1	Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)	31%	100%
B7GW85	Acinetobacter baumannii (strain AB307-0294)	29%	100%
B7IBV9	Acinetobacter baumannii (strain AB0057)	29%	100%
B9LB04	Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)	31%	97%
C5D9H5	Geobacillus sp. (strain WCH70)	31%	100%
D0A4P2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	99%
E9B3L9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
O13396	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	100%
O24617	Arabidopsis thaliana	33%	100%
O74502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	75%
O74773	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	96%
P25847	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	97%
P43246	Homo sapiens	33%	100%
P43247	Mus musculus	33%	100%
P43248	Drosophila melanogaster	31%	100%
P54275	Rattus norvegicus	33%	100%
P61672	Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)	29%	100%
Q03R33	Levilactobacillus brevis (strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG 11437 / NCIMB 947 / NCTC 947)	30%	100%
Q07V29	Rhodopseudomonas palustris (strain BisA53)	30%	100%
Q1WT15	Ligilactobacillus salivarius (strain UCC118)	30%	100%
Q24X61	Desulfitobacterium hafniense (strain Y51)	31%	100%
Q2JT35	Synechococcus sp. (strain JA-3-3Ab)	30%	100%
Q3JYM3	Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)	28%	100%
Q3M892	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	28%	100%
Q3MHE4	Bos taurus	33%	100%
Q49X88	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	29%	100%
Q4Q4J6	Leishmania major	96%	100%
Q553L4	Dictyostelium discoideum	33%	100%
Q5NYP9	Aromatoleum aromaticum (strain EbN1)	31%	100%
Q5UZG9	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	27%	100%
Q5XXB5	Chlorocebus aethiops	33%	100%
Q60BA1	Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)	30%	100%
Q65JE2	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	31%	100%
Q6G542	Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)	28%	100%
Q8DWW1	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	28%	100%
Q8E2R3	Streptococcus agalactiae serotype III (strain NEM316)	28%	100%
Q9XGC9	Zea mays	31%	100%
V5BB82	Trypanosoma cruzi	58%	98%
V5BK71	Trypanosoma cruzi	28%	100%