Kinetoplast-associated_protein_p18-2_putative/Gen eDB:LmjF.32.3770

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast-associated protein p18-2, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IGK7_LEIDO

TriTrypDb:

LdBPK_323920.1 , LdCL_320045200 , LDHU3_32.5050

Length:

132

Annotations

Annotations by Jardim et al.

Kinetoplastid proteins, kinetoplast-associated p18-2

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3Q8IGK7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGK7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	7	13	PF00089	0.377
CLV_NRD_NRD_1	119	121	PF00675	0.505
CLV_NRD_NRD_1	130	132	PF00675	0.500
CLV_NRD_NRD_1	3	5	PF00675	0.574
CLV_NRD_NRD_1	54	56	PF00675	0.388
CLV_NRD_NRD_1	72	74	PF00675	0.326
CLV_NRD_NRD_1	76	78	PF00675	0.413
CLV_PCSK_KEX2_1	3	5	PF00082	0.574
CLV_PCSK_KEX2_1	54	56	PF00082	0.423
CLV_PCSK_KEX2_1	72	74	PF00082	0.326

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NSD7	Trypanosomatidae	35%	73%
A0A3Q8ITR1	Leishmania donovani	38%	97%
A0A422P329	Trypanosoma rangeli	33%	69%
A4HL14	Leishmania braziliensis	57%	100%
A4HL15	Leishmania braziliensis	40%	100%
A4I8J5	Leishmania infantum	100%	100%
A4I8J6	Leishmania infantum	38%	100%
E9B3F5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
E9B3F6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
Q4Q4P4	Leishmania major	42%	100%

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