LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IGG6_LEIDO
TriTrypDb:
LdBPK_364630.1 , LdCL_360053400 , LDHU3_36.6250
Length:
194

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 5
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGG6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGG6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 181 185 PF00656 0.627
CLV_NRD_NRD_1 109 111 PF00675 0.581
CLV_NRD_NRD_1 148 150 PF00675 0.622
CLV_NRD_NRD_1 2 4 PF00675 0.625
CLV_NRD_NRD_1 65 67 PF00675 0.523
CLV_NRD_NRD_1 73 75 PF00675 0.485
CLV_PCSK_KEX2_1 108 110 PF00082 0.607
CLV_PCSK_KEX2_1 123 125 PF00082 0.373
CLV_PCSK_KEX2_1 131 133 PF00082 0.444
CLV_PCSK_KEX2_1 2 4 PF00082 0.625
CLV_PCSK_KEX2_1 72 74 PF00082 0.454
CLV_PCSK_PC1ET2_1 123 125 PF00082 0.495
CLV_PCSK_PC1ET2_1 131 133 PF00082 0.408
CLV_PCSK_PC1ET2_1 72 74 PF00082 0.454
CLV_PCSK_SKI1_1 117 121 PF00082 0.464
CLV_PCSK_SKI1_1 7 11 PF00082 0.497
DEG_Nend_UBRbox_1 1 4 PF02207 0.628
DOC_PP2B_LxvP_1 25 28 PF13499 0.505
DOC_USP7_MATH_1 26 30 PF00917 0.597
DOC_WW_Pin1_4 7 12 PF00397 0.517
LIG_14-3-3_CanoR_1 164 172 PF00244 0.530
LIG_BIR_III_4 184 188 PF00653 0.615
LIG_FHA_1 10 16 PF00498 0.723
LIG_FHA_1 165 171 PF00498 0.606
LIG_FHA_2 59 65 PF00498 0.501
LIG_FHA_2 84 90 PF00498 0.536
LIG_LIR_Apic_2 90 96 PF02991 0.514
LIG_SH2_STAT5 41 44 PF00017 0.524
LIG_TRAF2_1 95 98 PF00917 0.496
MOD_CK1_1 29 35 PF00069 0.566
MOD_CK1_1 40 46 PF00069 0.604
MOD_CK2_1 165 171 PF00069 0.553
MOD_DYRK1A_RPxSP_1 7 11 PF00069 0.497
MOD_GlcNHglycan 29 32 PF01048 0.574
MOD_GlcNHglycan 42 45 PF01048 0.486
MOD_GSK3_1 186 193 PF00069 0.681
MOD_GSK3_1 26 33 PF00069 0.598
MOD_NEK2_1 55 60 PF00069 0.510
MOD_PKA_2 58 64 PF00069 0.530
MOD_Plk_1 37 43 PF00069 0.583
MOD_Plk_4 37 43 PF00069 0.471
MOD_ProDKin_1 7 13 PF00069 0.517
MOD_SUMO_rev_2 180 188 PF00179 0.552
TRG_DiLeu_BaEn_4 97 103 PF01217 0.553
TRG_ER_diArg_1 1 3 PF00400 0.637
TRG_ER_diArg_1 108 110 PF00400 0.513
TRG_ER_diArg_1 57 60 PF00400 0.634
TRG_ER_diArg_1 73 76 PF00400 0.404
TRG_Pf-PMV_PEXEL_1 73 77 PF00026 0.535

Homologs

Protein Taxonomy Sequence identity Coverage
A4HPV8 Leishmania braziliensis 68% 100%
A4IDM0 Leishmania infantum 98% 100%
D0A4A7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 50% 100%
E9ATM5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 99%
Q4Q0X3 Leishmania major 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS