Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IGF8_LEIDO

TriTrypDb:

LdCL_250008600 , LDHU3_25.0420

Length:

330

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGF8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGF8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	175	179	PF00656	0.457
CLV_NRD_NRD_1	194	196	PF00675	0.467
CLV_NRD_NRD_1	247	249	PF00675	0.476
CLV_PCSK_FUR_1	245	249	PF00082	0.476
CLV_PCSK_KEX2_1	247	249	PF00082	0.476
CLV_PCSK_KEX2_1	317	319	PF00082	0.479
CLV_PCSK_PC1ET2_1	317	319	PF00082	0.478
CLV_PCSK_SKI1_1	122	126	PF00082	0.467
CLV_PCSK_SKI1_1	16	20	PF00082	0.405
DEG_Nend_Nbox_1	1	3	PF02207	0.441
DOC_CDC14_PxL_1	83	91	PF14671	0.404
DOC_CYCLIN_RxL_1	119	130	PF00134	0.442
DOC_CYCLIN_yCln2_LP_2	137	143	PF00134	0.404
DOC_MAPK_gen_1	108	116	PF00069	0.395
DOC_MAPK_gen_1	159	167	PF00069	0.414
DOC_MAPK_MEF2A_6	128	137	PF00069	0.439
DOC_MAPK_MEF2A_6	159	167	PF00069	0.414
DOC_MAPK_MEF2A_6	70	78	PF00069	0.387
DOC_PP1_RVXF_1	120	127	PF00149	0.424
DOC_PP1_RVXF_1	162	168	PF00149	0.425
DOC_PP2B_LxvP_1	141	144	PF13499	0.408
DOC_USP7_MATH_1	147	151	PF00917	0.693
DOC_USP7_MATH_1	179	183	PF00917	0.549
DOC_USP7_MATH_1	274	278	PF00917	0.528
DOC_USP7_UBL2_3	81	85	PF12436	0.381
DOC_WW_Pin1_4	25	30	PF00397	0.362
LIG_14-3-3_CanoR_1	122	127	PF00244	0.471
LIG_14-3-3_CanoR_1	16	24	PF00244	0.411
LIG_14-3-3_CanoR_1	195	199	PF00244	0.459
LIG_14-3-3_CanoR_1	247	252	PF00244	0.476
LIG_14-3-3_CanoR_1	40	49	PF00244	0.502
LIG_14-3-3_CanoR_1	51	56	PF00244	0.604
LIG_14-3-3_CterR_2	326	330	PF00244	0.536
LIG_APCC_ABBAyCdc20_2	183	189	PF00400	0.445
LIG_BRCT_BRCA1_1	254	258	PF00533	0.493
LIG_deltaCOP1_diTrp_1	10	19	PF00928	0.402
LIG_FHA_1	155	161	PF00498	0.385
LIG_FHA_1	18	24	PF00498	0.410
LIG_FHA_1	48	54	PF00498	0.376
LIG_FHA_2	277	283	PF00498	0.586
LIG_LIR_Gen_1	205	214	PF02991	0.402
LIG_LIR_Gen_1	255	266	PF02991	0.694
LIG_LIR_Gen_1	33	42	PF02991	0.452
LIG_LIR_Nem_3	10	15	PF02991	0.388
LIG_LIR_Nem_3	205	209	PF02991	0.391
LIG_LIR_Nem_3	255	261	PF02991	0.695
LIG_LIR_Nem_3	3	7	PF02991	0.635
LIG_LIR_Nem_3	33	37	PF02991	0.416
LIG_MYND_3	86	90	PF01753	0.407
LIG_MYND_3	92	96	PF01753	0.417
LIG_PDZ_Class_1	325	330	PF00595	0.536
LIG_Pex14_2	227	231	PF04695	0.435
LIG_PTB_Apo_2	77	84	PF02174	0.376
LIG_SH2_CRK	211	215	PF00017	0.416
LIG_SH2_GRB2like	172	175	PF00017	0.442
LIG_SH2_NCK_1	153	157	PF00017	0.392
LIG_SH2_NCK_1	211	215	PF00017	0.416
LIG_SH2_STAP1	206	210	PF00017	0.397
LIG_SH2_STAT5	148	151	PF00017	0.461
LIG_SH2_STAT5	211	214	PF00017	0.512
LIG_SH2_STAT5	34	37	PF00017	0.603
LIG_SH3_1	317	323	PF00018	0.468
LIG_SH3_2	321	326	PF14604	0.495
LIG_SH3_3	316	322	PF00018	0.494
LIG_SH3_3	46	52	PF00018	0.410
LIG_SH3_3	76	82	PF00018	0.397
LIG_SH3_4	81	88	PF00018	0.387
LIG_SUMO_SIM_par_1	50	58	PF11976	0.430
LIG_UBA3_1	74	81	PF00899	0.382
LIG_WRC_WIRS_1	15	20	PF05994	0.478
MOD_CK1_1	154	160	PF00069	0.415
MOD_CK1_1	17	23	PF00069	0.425
MOD_CK1_1	252	258	PF00069	0.637
MOD_CK1_1	267	273	PF00069	0.449
MOD_CK1_1	301	307	PF00069	0.492
MOD_CK2_1	112	118	PF00069	0.403
MOD_CK2_1	276	282	PF00069	0.639
MOD_CK2_1	51	57	PF00069	0.603
MOD_GlcNHglycan	149	152	PF01048	0.641
MOD_GlcNHglycan	240	243	PF01048	0.536
MOD_GlcNHglycan	42	45	PF01048	0.463
MOD_GSK3_1	122	129	PF00069	0.504
MOD_GSK3_1	147	154	PF00069	0.555
MOD_GSK3_1	190	197	PF00069	0.503
MOD_GSK3_1	249	256	PF00069	0.522
MOD_GSK3_1	272	279	PF00069	0.750
MOD_GSK3_1	284	291	PF00069	0.558
MOD_GSK3_1	297	304	PF00069	0.510
MOD_GSK3_1	47	54	PF00069	0.373
MOD_NEK2_1	19	24	PF00069	0.459
MOD_NEK2_1	209	214	PF00069	0.418
MOD_NEK2_1	240	245	PF00069	0.618
MOD_NEK2_1	261	266	PF00069	0.551
MOD_NEK2_1	297	302	PF00069	0.494
MOD_PIKK_1	17	23	PF00454	0.407
MOD_PIKK_1	209	215	PF00454	0.423
MOD_PIKK_1	65	71	PF00454	0.592
MOD_PK_1	247	253	PF00069	0.478
MOD_PKA_1	247	253	PF00069	0.478
MOD_PKA_2	194	200	PF00069	0.450
MOD_PKA_2	247	253	PF00069	0.478
MOD_PKB_1	245	253	PF00069	0.477
MOD_Plk_2-3	112	118	PF00069	0.566
MOD_Plk_4	112	118	PF00069	0.613
MOD_Plk_4	19	25	PF00069	0.478
MOD_Plk_4	30	36	PF00069	0.424
MOD_Plk_4	51	57	PF00069	0.504
MOD_Plk_4	8	14	PF00069	0.568
MOD_ProDKin_1	25	31	PF00069	0.357
MOD_SUMO_rev_2	129	137	PF00179	0.438
TRG_DiLeu_BaLyEn_6	37	42	PF01217	0.460
TRG_ENDOCYTIC_2	15	18	PF00928	0.369
TRG_ENDOCYTIC_2	206	209	PF00928	0.391
TRG_ENDOCYTIC_2	34	37	PF00928	0.381
TRG_ENDOCYTIC_2	4	7	PF00928	0.461
TRG_ER_diArg_1	245	248	PF00400	0.478

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3R7NA09	Trypanosoma rangeli	29%	71%
V5DPA4	Trypanosoma cruzi	31%	71%