Transcription like protein nupm1, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription like protein nupm1, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IGF6_LEIDO

TriTrypDb:

LdBPK_311980.1 , LdCL_310027600 , LDHU3_31.3550

Length:

478

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3Q8IGF6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGF6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	373	377	PF00656	0.639
CLV_NRD_NRD_1	105	107	PF00675	0.416
CLV_NRD_NRD_1	111	113	PF00675	0.407
CLV_NRD_NRD_1	234	236	PF00675	0.405
CLV_NRD_NRD_1	284	286	PF00675	0.475
CLV_NRD_NRD_1	48	50	PF00675	0.481
CLV_NRD_NRD_1	51	53	PF00675	0.470
CLV_PCSK_FUR_1	231	235	PF00082	0.407
CLV_PCSK_FUR_1	49	53	PF00082	0.442
CLV_PCSK_KEX2_1	103	105	PF00082	0.396
CLV_PCSK_KEX2_1	111	113	PF00082	0.404
CLV_PCSK_KEX2_1	233	235	PF00082	0.409
CLV_PCSK_KEX2_1	283	285	PF00082	0.482
CLV_PCSK_KEX2_1	413	415	PF00082	0.482
CLV_PCSK_KEX2_1	48	50	PF00082	0.478
CLV_PCSK_KEX2_1	51	53	PF00082	0.468
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.396
CLV_PCSK_PC1ET2_1	413	415	PF00082	0.461
CLV_PCSK_PC7_1	229	235	PF00082	0.390
CLV_Separin_Metazoa	92	96	PF03568	0.597
DEG_Kelch_Keap1_1	62	67	PF01344	0.733
DEG_SCF_FBW7_2	85	92	PF00400	0.615
DEG_SPOP_SBC_1	159	163	PF00917	0.692
DEG_SPOP_SBC_1	265	269	PF00917	0.648
DOC_CKS1_1	429	434	PF01111	0.649
DOC_PP2B_LxvP_1	173	176	PF13499	0.654
DOC_PP2B_LxvP_1	36	39	PF13499	0.613
DOC_PP2B_LxvP_1	458	461	PF13499	0.706
DOC_PP4_FxxP_1	429	432	PF00568	0.660
DOC_USP7_MATH_1	141	145	PF00917	0.738
DOC_USP7_MATH_1	289	293	PF00917	0.752
DOC_USP7_MATH_1	300	304	PF00917	0.662
DOC_USP7_MATH_1	355	359	PF00917	0.745
DOC_USP7_MATH_1	443	447	PF00917	0.697
DOC_USP7_MATH_1	454	458	PF00917	0.664
DOC_USP7_MATH_1	464	468	PF00917	0.646
DOC_USP7_MATH_1	79	83	PF00917	0.644
DOC_USP7_UBL2_3	413	417	PF12436	0.675
DOC_USP7_UBL2_3	97	101	PF12436	0.563
DOC_WW_Pin1_4	344	349	PF00397	0.674
DOC_WW_Pin1_4	361	366	PF00397	0.649
DOC_WW_Pin1_4	376	381	PF00397	0.676
DOC_WW_Pin1_4	428	433	PF00397	0.660
DOC_WW_Pin1_4	53	58	PF00397	0.676
DOC_WW_Pin1_4	85	90	PF00397	0.620
LIG_14-3-3_CanoR_1	149	159	PF00244	0.689
LIG_14-3-3_CanoR_1	160	166	PF00244	0.700
LIG_14-3-3_CanoR_1	169	173	PF00244	0.613
LIG_14-3-3_CanoR_1	209	217	PF00244	0.642
LIG_14-3-3_CanoR_1	302	307	PF00244	0.708
LIG_BRCT_BRCA1_1	176	180	PF00533	0.636
LIG_BRCT_BRCA1_1	323	327	PF00533	0.675
LIG_BRCT_BRCA1_1	425	429	PF00533	0.676
LIG_Clathr_ClatBox_1	328	332	PF01394	0.670
LIG_FHA_1	160	166	PF00498	0.689
LIG_FHA_1	179	185	PF00498	0.608
LIG_FHA_2	318	324	PF00498	0.663
LIG_FHA_2	413	419	PF00498	0.650
LIG_LIR_Apic_2	170	175	PF02991	0.725
LIG_LIR_Apic_2	426	432	PF02991	0.660
LIG_LIR_Nem_3	323	328	PF02991	0.719
LIG_LIR_Nem_3	415	419	PF02991	0.650
LIG_LIR_Nem_3	72	78	PF02991	0.748
LIG_LYPXL_yS_3	325	328	PF13949	0.719
LIG_MLH1_MIPbox_1	425	429	PF16413	0.676
LIG_MYND_1	85	89	PF01753	0.619
LIG_PCNA_yPIPBox_3	417	429	PF02747	0.666
LIG_Pex14_2	21	25	PF04695	0.301
LIG_SH2_GRB2like	370	373	PF00017	0.660
LIG_SH2_STAP1	249	253	PF00017	0.605
LIG_SH2_STAT5	172	175	PF00017	0.675
LIG_SH2_STAT5	223	226	PF00017	0.581
LIG_SH2_STAT5	32	35	PF00017	0.589
LIG_SH3_3	458	464	PF00018	0.716
LIG_SH3_3	468	474	PF00018	0.640
LIG_Sin3_3	7	14	PF02671	0.244
LIG_TRAF2_1	107	110	PF00917	0.597
LIG_TRAF2_1	89	92	PF00917	0.611
LIG_WW_3	83	87	PF00397	0.533
MOD_CK1_1	144	150	PF00069	0.640
MOD_CK1_1	154	160	PF00069	0.659
MOD_CK1_1	195	201	PF00069	0.635
MOD_CK1_1	204	210	PF00069	0.614
MOD_CK1_1	213	219	PF00069	0.597
MOD_CK1_1	256	262	PF00069	0.576
MOD_CK1_1	264	270	PF00069	0.618
MOD_CK1_1	305	311	PF00069	0.620
MOD_CK1_1	354	360	PF00069	0.583
MOD_CK1_1	371	377	PF00069	0.699
MOD_CK1_1	439	445	PF00069	0.733
MOD_CK1_1	62	68	PF00069	0.586
MOD_CK2_1	133	139	PF00069	0.637
MOD_CK2_1	251	257	PF00069	0.488
MOD_CK2_1	317	323	PF00069	0.575
MOD_CK2_1	331	337	PF00069	0.497
MOD_CK2_1	61	67	PF00069	0.688
MOD_GlcNHglycan	14	17	PF01048	0.338
MOD_GlcNHglycan	153	156	PF01048	0.663
MOD_GlcNHglycan	176	179	PF01048	0.642
MOD_GlcNHglycan	197	200	PF01048	0.667
MOD_GlcNHglycan	206	209	PF01048	0.586
MOD_GlcNHglycan	274	278	PF01048	0.622
MOD_GlcNHglycan	3	6	PF01048	0.461
MOD_GlcNHglycan	302	305	PF01048	0.657
MOD_GlcNHglycan	308	311	PF01048	0.594
MOD_GlcNHglycan	353	356	PF01048	0.628
MOD_GlcNHglycan	357	360	PF01048	0.586
MOD_GlcNHglycan	383	386	PF01048	0.622
MOD_GlcNHglycan	395	398	PF01048	0.599
MOD_GlcNHglycan	425	428	PF01048	0.593
MOD_GlcNHglycan	458	461	PF01048	0.631
MOD_GlcNHglycan	64	67	PF01048	0.585
MOD_GSK3_1	141	148	PF00069	0.611
MOD_GSK3_1	150	157	PF00069	0.624
MOD_GSK3_1	174	181	PF00069	0.731
MOD_GSK3_1	200	207	PF00069	0.657
MOD_GSK3_1	252	259	PF00069	0.547
MOD_GSK3_1	261	268	PF00069	0.620
MOD_GSK3_1	285	292	PF00069	0.624
MOD_GSK3_1	302	309	PF00069	0.638
MOD_GSK3_1	317	324	PF00069	0.599
MOD_GSK3_1	340	347	PF00069	0.654
MOD_GSK3_1	351	358	PF00069	0.600
MOD_GSK3_1	368	375	PF00069	0.527
MOD_GSK3_1	393	400	PF00069	0.572
MOD_GSK3_1	439	446	PF00069	0.725
MOD_N-GLC_1	355	360	PF02516	0.607
MOD_N-GLC_1	371	376	PF02516	0.531
MOD_NEK2_1	1	6	PF00069	0.480
MOD_NEK2_1	258	263	PF00069	0.740
MOD_NEK2_1	465	470	PF00069	0.564
MOD_NEK2_1	60	65	PF00069	0.681
MOD_NEK2_2	155	160	PF00069	0.578
MOD_NEK2_2	178	183	PF00069	0.580
MOD_PIKK_1	110	116	PF00454	0.501
MOD_PIKK_1	210	216	PF00454	0.574
MOD_PIKK_1	266	272	PF00454	0.692
MOD_PIKK_1	340	346	PF00454	0.614
MOD_PK_1	302	308	PF00069	0.637
MOD_PKA_1	283	289	PF00069	0.594
MOD_PKA_2	110	116	PF00069	0.501
MOD_PKA_2	148	154	PF00069	0.613
MOD_PKA_2	159	165	PF00069	0.628
MOD_PKA_2	168	174	PF00069	0.504
MOD_PKA_2	192	198	PF00069	0.691
MOD_PKA_2	201	207	PF00069	0.577
MOD_PKA_2	210	216	PF00069	0.466
MOD_PKA_2	283	289	PF00069	0.594
MOD_PKB_1	283	291	PF00069	0.665
MOD_Plk_1	178	184	PF00069	0.580
MOD_Plk_1	465	471	PF00069	0.594
MOD_Plk_4	168	174	PF00069	0.671
MOD_Plk_4	219	225	PF00069	0.470
MOD_ProDKin_1	344	350	PF00069	0.586
MOD_ProDKin_1	361	367	PF00069	0.557
MOD_ProDKin_1	376	382	PF00069	0.594
MOD_ProDKin_1	428	434	PF00069	0.573
MOD_ProDKin_1	53	59	PF00069	0.592
MOD_ProDKin_1	85	91	PF00069	0.510
TRG_DiLeu_BaEn_2	322	328	PF01217	0.571
TRG_DiLeu_BaEn_4	236	242	PF01217	0.482
TRG_ENDOCYTIC_2	249	252	PF00928	0.562
TRG_ENDOCYTIC_2	325	328	PF00928	0.582
TRG_ER_diArg_1	104	106	PF00400	0.500
TRG_ER_diArg_1	224	227	PF00400	0.495
TRG_ER_diArg_1	229	232	PF00400	0.493
TRG_ER_diArg_1	233	235	PF00400	0.499
TRG_ER_diArg_1	283	285	PF00400	0.696
TRG_ER_diArg_1	48	50	PF00400	0.626
TRG_NLS_MonoCore_2	102	107	PF00514	0.447
TRG_NLS_MonoExtN_4	101	107	PF00514	0.476
TRG_Pf-PMV_PEXEL_1	312	316	PF00026	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGX0	Leptomonas seymouri	47%	98%
A4HJH6	Leishmania braziliensis	61%	97%
A4HJX3	Leishmania braziliensis	61%	97%
A4I6W9	Leishmania infantum	98%	100%
E9B1Z3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q668	Leishmania major	89%	100%