Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IGF1_LEIDO

TriTrypDb:

LdBPK_313020.1 , LdCL_310038500 , LDHU3_31.5190

Length:

247

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGF1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGF1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.746
CLV_NRD_NRD_1	108	110	PF00675	0.581
CLV_NRD_NRD_1	214	216	PF00675	0.625
CLV_NRD_NRD_1	245	247	PF00675	0.727
CLV_NRD_NRD_1	91	93	PF00675	0.492
CLV_PCSK_FUR_1	105	109	PF00082	0.521
CLV_PCSK_KEX2_1	105	107	PF00082	0.577
CLV_PCSK_KEX2_1	108	110	PF00082	0.581
CLV_PCSK_KEX2_1	214	216	PF00082	0.625
CLV_PCSK_KEX2_1	245	247	PF00082	0.727
CLV_PCSK_KEX2_1	91	93	PF00082	0.492
CLV_PCSK_SKI1_1	42	46	PF00082	0.438
DEG_APCC_DBOX_1	41	49	PF00400	0.441
DEG_SCF_FBW7_1	142	149	PF00400	0.689
DEG_SPOP_SBC_1	184	188	PF00917	0.670
DOC_MAPK_MEF2A_6	147	154	PF00069	0.579
DOC_WW_Pin1_4	142	147	PF00397	0.649
DOC_WW_Pin1_4	170	175	PF00397	0.683
DOC_WW_Pin1_4	185	190	PF00397	0.645
DOC_WW_Pin1_4	4	9	PF00397	0.739
DOC_WW_Pin1_4	53	58	PF00397	0.647
LIG_14-3-3_CanoR_1	17	26	PF00244	0.459
LIG_14-3-3_CanoR_1	50	58	PF00244	0.563
LIG_14-3-3_CanoR_1	99	105	PF00244	0.570
LIG_14-3-3_CterR_2	245	247	PF00244	0.666
LIG_BRCT_BRCA1_1	65	69	PF00533	0.709
LIG_eIF4E_1	41	47	PF01652	0.438
LIG_FHA_2	88	94	PF00498	0.531
LIG_MYND_1	142	146	PF01753	0.614
LIG_SH2_STAT5	51	54	PF00017	0.481
LIG_SH3_2	210	215	PF14604	0.623
LIG_SH3_3	207	213	PF00018	0.643
LIG_SUMO_SIM_par_1	148	155	PF11976	0.574
LIG_SUMO_SIM_par_1	180	188	PF11976	0.671
MOD_CDK_SPK_2	142	147	PF00069	0.690
MOD_CDK_SPK_2	170	175	PF00069	0.640
MOD_CDK_SPxK_1	4	10	PF00069	0.683
MOD_CK1_1	170	176	PF00069	0.712
MOD_CK1_1	228	234	PF00069	0.746
MOD_CK1_1	33	39	PF00069	0.466
MOD_CK1_1	56	62	PF00069	0.698
MOD_CK1_1	67	73	PF00069	0.595
MOD_CK2_1	67	73	PF00069	0.686
MOD_CK2_1	87	93	PF00069	0.491
MOD_Cter_Amidation	243	246	PF01082	0.732
MOD_GlcNHglycan	115	118	PF01048	0.640
MOD_GlcNHglycan	165	168	PF01048	0.735
MOD_GlcNHglycan	19	22	PF01048	0.451
MOD_GlcNHglycan	205	208	PF01048	0.554
MOD_GlcNHglycan	230	233	PF01048	0.642
MOD_GlcNHglycan	66	69	PF01048	0.619
MOD_GSK3_1	142	149	PF00069	0.750
MOD_GSK3_1	163	170	PF00069	0.620
MOD_GSK3_1	180	187	PF00069	0.499
MOD_GSK3_1	52	59	PF00069	0.585
MOD_GSK3_1	63	70	PF00069	0.625
MOD_N-GLC_1	184	189	PF02516	0.668
MOD_NEK2_1	163	168	PF00069	0.710
MOD_NEK2_1	52	57	PF00069	0.502
MOD_NEK2_1	84	89	PF00069	0.547
MOD_NEK2_2	100	105	PF00069	0.559
MOD_PIKK_1	236	242	PF00454	0.673
MOD_PKA_1	108	114	PF00069	0.533
MOD_PKA_2	108	114	PF00069	0.569
MOD_PKA_2	30	36	PF00069	0.483
MOD_PKB_1	106	114	PF00069	0.530
MOD_Plk_1	158	164	PF00069	0.641
MOD_ProDKin_1	142	148	PF00069	0.649
MOD_ProDKin_1	170	176	PF00069	0.685
MOD_ProDKin_1	185	191	PF00069	0.647
MOD_ProDKin_1	4	10	PF00069	0.736
MOD_ProDKin_1	53	59	PF00069	0.655
TRG_ER_diArg_1	104	107	PF00400	0.579
TRG_ER_diArg_1	213	215	PF00400	0.623
TRG_ER_diArg_1	217	220	PF00400	0.630
TRG_Pf-PMV_PEXEL_1	235	240	PF00026	0.642

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCN9	Leptomonas seymouri	39%	99%
A4HJT0	Leishmania braziliensis	72%	100%
A4I796	Leishmania infantum	99%	100%
E9B291	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q5W7	Leishmania major	94%	100%