LeishMANIAdb
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CUB domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CUB domain-containing protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3Q8IGD5_LEIDO
TriTrypDb:
LdCL_250005600 , LDHU3_25.0080
Length:
118

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IGD5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IGD5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 6 8 PF00675 0.507
CLV_PCSK_SKI1_1 69 73 PF00082 0.461
DEG_Nend_UBRbox_2 1 3 PF02207 0.481
DOC_MAPK_MEF2A_6 79 86 PF00069 0.481
DOC_PP2B_LxvP_1 115 118 PF13499 0.436
DOC_PP4_FxxP_1 41 44 PF00568 0.391
DOC_SPAK_OSR1_1 22 26 PF12202 0.478
DOC_USP7_MATH_1 15 19 PF00917 0.438
DOC_WW_Pin1_4 110 115 PF00397 0.542
DOC_WW_Pin1_4 48 53 PF00397 0.539
LIG_14-3-3_CanoR_1 22 28 PF00244 0.428
LIG_BRCT_BRCA1_1 19 23 PF00533 0.504
LIG_BRCT_BRCA1_1 50 54 PF00533 0.569
LIG_CSL_BTD_1 115 118 PF09270 0.436
LIG_FHA_1 34 40 PF00498 0.452
LIG_FHA_1 54 60 PF00498 0.195
LIG_FHA_1 70 76 PF00498 0.444
LIG_FHA_1 81 87 PF00498 0.362
LIG_FHA_2 30 36 PF00498 0.535
LIG_FHA_2 56 62 PF00498 0.435
LIG_FXI_DFP_1 92 96 PF00024 0.507
LIG_LIR_Gen_1 35 44 PF02991 0.465
LIG_LIR_Gen_1 51 59 PF02991 0.407
LIG_LIR_Nem_3 35 40 PF02991 0.416
LIG_LIR_Nem_3 51 57 PF02991 0.367
LIG_LIR_Nem_3 70 74 PF02991 0.440
LIG_Pex14_2 37 41 PF04695 0.482
LIG_SH2_STAT5 91 94 PF00017 0.299
LIG_SH3_3 46 52 PF00018 0.592
LIG_SUMO_SIM_par_1 55 61 PF11976 0.473
LIG_SUMO_SIM_par_1 82 89 PF11976 0.470
LIG_WRC_WIRS_1 34 39 PF05994 0.321
MOD_CK1_1 42 48 PF00069 0.460
MOD_CK2_1 55 61 PF00069 0.462
MOD_GlcNHglycan 87 91 PF01048 0.450
MOD_GSK3_1 29 36 PF00069 0.462
MOD_GSK3_1 53 60 PF00069 0.403
MOD_N-GLC_1 23 28 PF02516 0.487
MOD_NEK2_1 16 21 PF00069 0.441
MOD_NEK2_1 23 28 PF00069 0.374
MOD_NEK2_2 17 22 PF00069 0.520
MOD_Plk_1 23 29 PF00069 0.513
MOD_Plk_4 50 56 PF00069 0.564
MOD_Plk_4 80 86 PF00069 0.523
MOD_ProDKin_1 110 116 PF00069 0.545
MOD_ProDKin_1 48 54 PF00069 0.531
TRG_DiLeu_BaEn_2 49 55 PF01217 0.559

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7Y0 Leptomonas seymouri 61% 96%
A0A1X0NV93 Trypanosomatidae 28% 100%
A0A3R7RDZ1 Trypanosoma rangeli 29% 100%
C9ZQ63 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 98%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS