Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IG32_LEIDO

TriTrypDb:

LdBPK_310970.1 , LdCL_310016300 , LDHU3_31.1650

Length:

893

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IG32

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IG32

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	452	456	PF00656	0.606
CLV_C14_Caspase3-7	49	53	PF00656	0.589
CLV_C14_Caspase3-7	531	535	PF00656	0.785
CLV_C14_Caspase3-7	594	598	PF00656	0.783
CLV_C14_Caspase3-7	689	693	PF00656	0.643
CLV_NRD_NRD_1	191	193	PF00675	0.710
CLV_NRD_NRD_1	339	341	PF00675	0.654
CLV_NRD_NRD_1	362	364	PF00675	0.527
CLV_NRD_NRD_1	566	568	PF00675	0.703
CLV_NRD_NRD_1	603	605	PF00675	0.802
CLV_NRD_NRD_1	607	609	PF00675	0.741
CLV_NRD_NRD_1	68	70	PF00675	0.571
CLV_NRD_NRD_1	724	726	PF00675	0.701
CLV_NRD_NRD_1	747	749	PF00675	0.812
CLV_NRD_NRD_1	763	765	PF00675	0.527
CLV_NRD_NRD_1	778	780	PF00675	0.497
CLV_NRD_NRD_1	837	839	PF00675	0.629
CLV_NRD_NRD_1	859	861	PF00675	0.769
CLV_NRD_NRD_1	881	883	PF00675	0.687
CLV_PCSK_KEX2_1	191	193	PF00082	0.749
CLV_PCSK_KEX2_1	362	364	PF00082	0.488
CLV_PCSK_KEX2_1	566	568	PF00082	0.703
CLV_PCSK_KEX2_1	578	580	PF00082	0.796
CLV_PCSK_KEX2_1	603	605	PF00082	0.802
CLV_PCSK_KEX2_1	607	609	PF00082	0.741
CLV_PCSK_KEX2_1	724	726	PF00082	0.701
CLV_PCSK_KEX2_1	747	749	PF00082	0.812
CLV_PCSK_KEX2_1	763	765	PF00082	0.527
CLV_PCSK_KEX2_1	881	883	PF00082	0.687
CLV_PCSK_PC1ET2_1	578	580	PF00082	0.640
CLV_PCSK_PC7_1	187	193	PF00082	0.704
CLV_PCSK_PC7_1	603	609	PF00082	0.749
CLV_PCSK_SKI1_1	336	340	PF00082	0.503
CLV_PCSK_SKI1_1	362	366	PF00082	0.660
CLV_PCSK_SKI1_1	424	428	PF00082	0.682
CLV_PCSK_SKI1_1	458	462	PF00082	0.597
CLV_PCSK_SKI1_1	558	562	PF00082	0.647
CLV_PCSK_SKI1_1	566	570	PF00082	0.624
CLV_PCSK_SKI1_1	579	583	PF00082	0.637
CLV_PCSK_SKI1_1	608	612	PF00082	0.735
CLV_PCSK_SKI1_1	70	74	PF00082	0.631
CLV_PCSK_SKI1_1	748	752	PF00082	0.811
CLV_Separin_Metazoa	481	485	PF03568	0.626
DEG_APCC_DBOX_1	335	343	PF00400	0.547
DEG_APCC_DBOX_1	471	479	PF00400	0.627
DEG_COP1_1	367	375	PF00400	0.519
DEG_SCF_FBW7_1	176	181	PF00400	0.591
DEG_SIAH_1	171	179	PF03145	0.606
DEG_SPOP_SBC_1	222	226	PF00917	0.630
DEG_SPOP_SBC_1	229	233	PF00917	0.607
DEG_SPOP_SBC_1	502	506	PF00917	0.541
DEG_SPOP_SBC_1	728	732	PF00917	0.628
DOC_CKS1_1	716	721	PF01111	0.779
DOC_CYCLIN_yCln2_LP_2	631	637	PF00134	0.505
DOC_MAPK_gen_1	340	347	PF00069	0.648
DOC_MAPK_gen_1	472	479	PF00069	0.629
DOC_MAPK_gen_1	860	868	PF00069	0.665
DOC_MAPK_MEF2A_6	286	293	PF00069	0.720
DOC_MAPK_MEF2A_6	472	479	PF00069	0.629
DOC_MAPK_MEF2A_6	860	868	PF00069	0.726
DOC_MAPK_MEF2A_6	870	879	PF00069	0.594
DOC_MAPK_NFAT4_5	472	480	PF00069	0.630
DOC_PP1_RVXF_1	3	9	PF00149	0.726
DOC_PP1_RVXF_1	799	805	PF00149	0.678
DOC_USP7_MATH_1	15	19	PF00917	0.622
DOC_USP7_MATH_1	161	165	PF00917	0.685
DOC_USP7_MATH_1	180	184	PF00917	0.721
DOC_USP7_MATH_1	222	226	PF00917	0.645
DOC_USP7_MATH_1	230	234	PF00917	0.643
DOC_USP7_MATH_1	460	464	PF00917	0.735
DOC_USP7_MATH_1	525	529	PF00917	0.815
DOC_USP7_MATH_1	598	602	PF00917	0.745
DOC_USP7_MATH_1	700	704	PF00917	0.686
DOC_USP7_MATH_1	752	756	PF00917	0.815
DOC_USP7_UBL2_3	645	649	PF12436	0.544
DOC_WW_Pin1_4	157	162	PF00397	0.702
DOC_WW_Pin1_4	174	179	PF00397	0.521
DOC_WW_Pin1_4	285	290	PF00397	0.723
DOC_WW_Pin1_4	37	42	PF00397	0.598
DOC_WW_Pin1_4	371	376	PF00397	0.706
DOC_WW_Pin1_4	444	449	PF00397	0.568
DOC_WW_Pin1_4	559	564	PF00397	0.687
DOC_WW_Pin1_4	579	584	PF00397	0.507
DOC_WW_Pin1_4	625	630	PF00397	0.785
DOC_WW_Pin1_4	669	674	PF00397	0.654
DOC_WW_Pin1_4	715	720	PF00397	0.779
LIG_14-3-3_CanoR_1	105	115	PF00244	0.636
LIG_14-3-3_CanoR_1	14	24	PF00244	0.734
LIG_14-3-3_CanoR_1	205	213	PF00244	0.517
LIG_14-3-3_CanoR_1	418	426	PF00244	0.703
LIG_14-3-3_CanoR_1	450	454	PF00244	0.778
LIG_14-3-3_CanoR_1	507	514	PF00244	0.705
LIG_14-3-3_CanoR_1	607	613	PF00244	0.725
LIG_14-3-3_CanoR_1	681	690	PF00244	0.769
LIG_14-3-3_CanoR_1	729	738	PF00244	0.787
LIG_14-3-3_CanoR_1	763	769	PF00244	0.684
LIG_14-3-3_CanoR_1	838	845	PF00244	0.598
LIG_14-3-3_CanoR_1	867	877	PF00244	0.725
LIG_14-3-3_CanoR_1	91	98	PF00244	0.678
LIG_BIR_III_2	136	140	PF00653	0.726
LIG_BIR_III_2	151	155	PF00653	0.710
LIG_BIR_III_4	692	696	PF00653	0.569
LIG_BRCT_BRCA1_1	230	234	PF00533	0.788
LIG_BRCT_BRCA1_1	238	242	PF00533	0.585
LIG_BRCT_BRCA1_1	39	43	PF00533	0.637
LIG_BRCT_BRCA1_1	520	524	PF00533	0.829
LIG_Clathr_ClatBox_1	290	294	PF01394	0.709
LIG_Clathr_ClatBox_1	387	391	PF01394	0.667
LIG_Clathr_ClatBox_1	492	496	PF01394	0.545
LIG_CtBP_PxDLS_1	375	379	PF00389	0.603
LIG_eIF4E_1	487	493	PF01652	0.638
LIG_FHA_1	153	159	PF00498	0.760
LIG_FHA_1	184	190	PF00498	0.730
LIG_FHA_1	230	236	PF00498	0.592
LIG_FHA_1	625	631	PF00498	0.685
LIG_FHA_1	8	14	PF00498	0.682
LIG_FHA_2	594	600	PF00498	0.798
LIG_FHA_2	609	615	PF00498	0.750
LIG_FHA_2	703	709	PF00498	0.702
LIG_FHA_2	763	769	PF00498	0.635
LIG_FHA_2	822	828	PF00498	0.695
LIG_FHA_2	94	100	PF00498	0.641
LIG_Integrin_RGD_1	50	52	PF01839	0.587
LIG_LIR_Gen_1	109	120	PF02991	0.762
LIG_LIR_Gen_1	215	222	PF02991	0.653
LIG_LIR_Gen_1	389	397	PF02991	0.644
LIG_LIR_Gen_1	473	483	PF02991	0.529
LIG_LIR_Gen_1	606	616	PF02991	0.687
LIG_LIR_Gen_1	771	777	PF02991	0.531
LIG_LIR_Gen_1	82	90	PF02991	0.635
LIG_LIR_Nem_3	109	115	PF02991	0.750
LIG_LIR_Nem_3	177	182	PF02991	0.586
LIG_LIR_Nem_3	215	220	PF02991	0.653
LIG_LIR_Nem_3	389	393	PF02991	0.639
LIG_LIR_Nem_3	420	426	PF02991	0.589
LIG_LIR_Nem_3	473	479	PF02991	0.530
LIG_LIR_Nem_3	606	612	PF02991	0.697
LIG_LIR_Nem_3	614	619	PF02991	0.701
LIG_LIR_Nem_3	771	775	PF02991	0.529
LIG_LIR_Nem_3	82	86	PF02991	0.567
LIG_LYPXL_yS_3	848	851	PF13949	0.738
LIG_NRBOX	474	480	PF00104	0.627
LIG_Pex14_1	16	20	PF04695	0.627
LIG_Pex14_2	800	804	PF04695	0.615
LIG_PTAP_UEV_1	138	143	PF05743	0.769
LIG_SH2_CRK	265	269	PF00017	0.713
LIG_SH2_CRK	609	613	PF00017	0.756
LIG_SH2_CRK	83	87	PF00017	0.636
LIG_SH2_GRB2like	404	407	PF00017	0.590
LIG_SH2_GRB2like	83	86	PF00017	0.682
LIG_SH2_NCK_1	609	613	PF00017	0.756
LIG_SH2_SRC	83	86	PF00017	0.682
LIG_SH2_STAP1	640	644	PF00017	0.673
LIG_SH2_STAP1	83	87	PF00017	0.636
LIG_SH2_STAT5	20	23	PF00017	0.646
LIG_SH2_STAT5	395	398	PF00017	0.725
LIG_SH2_STAT5	487	490	PF00017	0.598
LIG_SH2_STAT5	491	494	PF00017	0.481
LIG_SH2_STAT5	640	643	PF00017	0.675
LIG_SH2_STAT5	850	853	PF00017	0.749
LIG_SH3_2	33	38	PF14604	0.634
LIG_SH3_2	583	588	PF14604	0.832
LIG_SH3_3	136	142	PF00018	0.669
LIG_SH3_3	30	36	PF00018	0.610
LIG_SH3_3	367	373	PF00018	0.712
LIG_SH3_3	394	400	PF00018	0.550
LIG_SH3_3	580	586	PF00018	0.827
LIG_SH3_3	880	886	PF00018	0.698
LIG_SUMO_SIM_anti_2	771	778	PF11976	0.537
LIG_SUMO_SIM_par_1	374	379	PF11976	0.520
LIG_SUMO_SIM_par_1	771	778	PF11976	0.537
LIG_TRAF2_1	60	63	PF00917	0.626
LIG_TRAF2_1	611	614	PF00917	0.747
LIG_TRAF2_1	824	827	PF00917	0.709
LIG_WRC_WIRS_1	387	392	PF05994	0.682
MOD_CDC14_SPxK_1	447	450	PF00782	0.579
MOD_CDK_SPK_2	669	674	PF00069	0.637
MOD_CDK_SPxK_1	444	450	PF00069	0.574
MOD_CDK_SPxK_1	715	721	PF00069	0.748
MOD_CDK_SPxxK_3	285	292	PF00069	0.717
MOD_CDK_SPxxK_3	37	44	PF00069	0.561
MOD_CDK_SPxxK_3	559	566	PF00069	0.759
MOD_CK1_1	146	152	PF00069	0.691
MOD_CK1_1	160	166	PF00069	0.708
MOD_CK1_1	183	189	PF00069	0.746
MOD_CK1_1	223	229	PF00069	0.773
MOD_CK1_1	374	380	PF00069	0.657
MOD_CK1_1	402	408	PF00069	0.757
MOD_CK1_1	416	422	PF00069	0.711
MOD_CK1_1	442	448	PF00069	0.763
MOD_CK1_1	527	533	PF00069	0.771
MOD_CK1_1	53	59	PF00069	0.571
MOD_CK1_1	617	623	PF00069	0.642
MOD_CK1_1	643	649	PF00069	0.777
MOD_CK1_1	688	694	PF00069	0.726
MOD_CK1_1	755	761	PF00069	0.778
MOD_CK1_1	837	843	PF00069	0.746
MOD_CK2_1	111	117	PF00069	0.574
MOD_CK2_1	376	382	PF00069	0.598
MOD_CK2_1	386	392	PF00069	0.433
MOD_CK2_1	525	531	PF00069	0.721
MOD_CK2_1	608	614	PF00069	0.758
MOD_CK2_1	821	827	PF00069	0.689
MOD_CK2_1	93	99	PF00069	0.643
MOD_Cter_Amidation	745	748	PF01082	0.748
MOD_Cter_Amidation	879	882	PF01082	0.574
MOD_DYRK1A_RPxSP_1	579	583	PF00069	0.773
MOD_GlcNHglycan	108	111	PF01048	0.557
MOD_GlcNHglycan	127	130	PF01048	0.677
MOD_GlcNHglycan	139	142	PF01048	0.638
MOD_GlcNHglycan	145	148	PF01048	0.574
MOD_GlcNHglycan	163	166	PF01048	0.574
MOD_GlcNHglycan	252	255	PF01048	0.630
MOD_GlcNHglycan	444	447	PF01048	0.613
MOD_GlcNHglycan	457	461	PF01048	0.655
MOD_GlcNHglycan	463	466	PF01048	0.634
MOD_GlcNHglycan	52	55	PF01048	0.551
MOD_GlcNHglycan	520	523	PF01048	0.736
MOD_GlcNHglycan	527	530	PF01048	0.627
MOD_GlcNHglycan	579	582	PF01048	0.819
MOD_GlcNHglycan	616	619	PF01048	0.672
MOD_GlcNHglycan	642	645	PF01048	0.698
MOD_GlcNHglycan	702	705	PF01048	0.685
MOD_GlcNHglycan	731	734	PF01048	0.760
MOD_GlcNHglycan	839	842	PF01048	0.719
MOD_GlcNHglycan	870	873	PF01048	0.752
MOD_GSK3_1	152	159	PF00069	0.677
MOD_GSK3_1	160	167	PF00069	0.724
MOD_GSK3_1	174	181	PF00069	0.610
MOD_GSK3_1	243	250	PF00069	0.530
MOD_GSK3_1	400	407	PF00069	0.672
MOD_GSK3_1	413	420	PF00069	0.765
MOD_GSK3_1	456	463	PF00069	0.641
MOD_GSK3_1	502	509	PF00069	0.702
MOD_GSK3_1	639	646	PF00069	0.638
MOD_GSK3_1	681	688	PF00069	0.844
MOD_GSK3_1	711	718	PF00069	0.807
MOD_GSK3_1	748	755	PF00069	0.824
MOD_GSK3_1	804	811	PF00069	0.745
MOD_LATS_1	89	95	PF00433	0.579
MOD_N-GLC_1	442	447	PF02516	0.737
MOD_N-GLC_1	795	800	PF02516	0.717
MOD_N-GLC_1	854	859	PF02516	0.624
MOD_NEK2_1	243	248	PF00069	0.624
MOD_NEK2_1	309	314	PF00069	0.445
MOD_NEK2_1	376	381	PF00069	0.476
MOD_NEK2_1	417	422	PF00069	0.661
MOD_NEK2_1	449	454	PF00069	0.741
MOD_NEK2_1	623	628	PF00069	0.707
MOD_NEK2_1	639	644	PF00069	0.533
MOD_NEK2_1	720	725	PF00069	0.842
MOD_NEK2_1	819	824	PF00069	0.672
MOD_NEK2_1	868	873	PF00069	0.735
MOD_NEK2_1	93	98	PF00069	0.710
MOD_NEK2_2	598	603	PF00069	0.742
MOD_NEK2_2	9	14	PF00069	0.762
MOD_OFUCOSY	818	823	PF10250	0.724
MOD_PIKK_1	152	158	PF00454	0.617
MOD_PIKK_1	180	186	PF00454	0.726
MOD_PIKK_1	506	512	PF00454	0.755
MOD_PIKK_1	91	97	PF00454	0.717
MOD_PKA_1	603	609	PF00069	0.615
MOD_PKA_2	1	7	PF00069	0.597
MOD_PKA_2	125	131	PF00069	0.774
MOD_PKA_2	417	423	PF00069	0.725
MOD_PKA_2	449	455	PF00069	0.800
MOD_PKA_2	502	508	PF00069	0.701
MOD_PKA_2	587	593	PF00069	0.842
MOD_PKA_2	603	609	PF00069	0.615
MOD_PKA_2	680	686	PF00069	0.782
MOD_PKA_2	720	726	PF00069	0.841
MOD_PKA_2	728	734	PF00069	0.759
MOD_PKA_2	762	768	PF00069	0.693
MOD_PKA_2	778	784	PF00069	0.594
MOD_PKA_2	804	810	PF00069	0.643
MOD_PKA_2	837	843	PF00069	0.669
MOD_PKB_1	501	509	PF00069	0.701
MOD_Plk_1	294	300	PF00069	0.716
MOD_Plk_1	598	604	PF00069	0.741
MOD_Plk_1	711	717	PF00069	0.795
MOD_Plk_2-3	111	117	PF00069	0.757
MOD_Plk_2-3	386	392	PF00069	0.675
MOD_Plk_4	230	236	PF00069	0.668
MOD_Plk_4	247	253	PF00069	0.408
MOD_Plk_4	309	315	PF00069	0.469
MOD_Plk_4	768	774	PF00069	0.540
MOD_ProDKin_1	157	163	PF00069	0.703
MOD_ProDKin_1	174	180	PF00069	0.515
MOD_ProDKin_1	285	291	PF00069	0.717
MOD_ProDKin_1	37	43	PF00069	0.599
MOD_ProDKin_1	371	377	PF00069	0.699
MOD_ProDKin_1	444	450	PF00069	0.574
MOD_ProDKin_1	559	565	PF00069	0.687
MOD_ProDKin_1	579	585	PF00069	0.504
MOD_ProDKin_1	625	631	PF00069	0.787
MOD_ProDKin_1	669	675	PF00069	0.654
MOD_ProDKin_1	715	721	PF00069	0.780
MOD_SUMO_for_1	347	350	PF00179	0.526
TRG_DiLeu_BaEn_2	391	397	PF01217	0.732
TRG_DiLeu_BaLyEn_6	286	291	PF01217	0.724
TRG_DiLeu_BaLyEn_6	626	631	PF01217	0.493
TRG_ENDOCYTIC_2	112	115	PF00928	0.754
TRG_ENDOCYTIC_2	609	612	PF00928	0.754
TRG_ENDOCYTIC_2	83	86	PF00928	0.639
TRG_ENDOCYTIC_2	848	851	PF00928	0.738
TRG_ER_diArg_1	191	193	PF00400	0.749
TRG_ER_diArg_1	323	326	PF00400	0.573
TRG_ER_diArg_1	362	364	PF00400	0.472
TRG_ER_diArg_1	483	486	PF00400	0.544
TRG_ER_diArg_1	566	568	PF00400	0.703
TRG_ER_diArg_1	602	604	PF00400	0.741
TRG_ER_diArg_1	607	609	PF00400	0.690
TRG_ER_diArg_1	762	764	PF00400	0.615
TRG_ER_diArg_1	791	794	PF00400	0.714
TRG_ER_diArg_1	881	883	PF00400	0.774
TRG_Pf-PMV_PEXEL_1	191	195	PF00026	0.708
TRG_Pf-PMV_PEXEL_1	363	367	PF00026	0.472
TRG_Pf-PMV_PEXEL_1	621	625	PF00026	0.754

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJ59	Leptomonas seymouri	31%	100%
A4I6M1	Leishmania infantum	99%	100%
E9B1P4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%
Q4Q6G6	Leishmania major	85%	100%