Sperm-tail PG-rich repeat, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IFZ9_LEIDO

TriTrypDb:

LdBPK_350420.1 , LdCL_350009300 , LDHU3_35.0580

Length:

491

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IFZ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFZ9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	138	140	PF00675	0.703
CLV_NRD_NRD_1	167	169	PF00675	0.384
CLV_NRD_NRD_1	184	186	PF00675	0.644
CLV_NRD_NRD_1	218	220	PF00675	0.777
CLV_NRD_NRD_1	258	260	PF00675	0.645
CLV_NRD_NRD_1	351	353	PF00675	0.391
CLV_NRD_NRD_1	487	489	PF00675	0.716
CLV_PCSK_FUR_1	167	171	PF00082	0.365
CLV_PCSK_KEX2_1	138	140	PF00082	0.743
CLV_PCSK_KEX2_1	167	169	PF00082	0.324
CLV_PCSK_KEX2_1	184	186	PF00082	0.508
CLV_PCSK_KEX2_1	218	220	PF00082	0.790
CLV_PCSK_KEX2_1	351	353	PF00082	0.388
CLV_PCSK_KEX2_1	487	489	PF00082	0.753
CLV_PCSK_PC1ET2_1	169	171	PF00082	0.327
CLV_PCSK_SKI1_1	169	173	PF00082	0.361
CLV_PCSK_SKI1_1	439	443	PF00082	0.593
CLV_PCSK_SKI1_1	98	102	PF00082	0.627
CLV_Separin_Metazoa	124	128	PF03568	0.707
DEG_SCF_FBW7_1	38	44	PF00400	0.598
DOC_ANK_TNKS_1	234	241	PF00023	0.565
DOC_CKS1_1	38	43	PF01111	0.599
DOC_CYCLIN_RxL_1	166	176	PF00134	0.557
DOC_USP7_MATH_1	10	14	PF00917	0.721
DOC_USP7_MATH_1	246	250	PF00917	0.656
DOC_USP7_MATH_1	288	292	PF00917	0.678
DOC_USP7_UBL2_3	204	208	PF12436	0.692
DOC_WW_Pin1_4	144	149	PF00397	0.659
DOC_WW_Pin1_4	240	245	PF00397	0.597
DOC_WW_Pin1_4	294	299	PF00397	0.705
DOC_WW_Pin1_4	305	310	PF00397	0.746
DOC_WW_Pin1_4	37	42	PF00397	0.620
DOC_WW_Pin1_4	58	63	PF00397	0.653
LIG_14-3-3_CanoR_1	170	178	PF00244	0.591
LIG_14-3-3_CanoR_1	225	229	PF00244	0.726
LIG_14-3-3_CanoR_1	352	358	PF00244	0.591
LIG_14-3-3_CanoR_1	360	367	PF00244	0.621
LIG_14-3-3_CanoR_1	450	454	PF00244	0.593
LIG_BIR_II_1	1	5	PF00653	0.621
LIG_BRCT_BRCA1_1	290	294	PF00533	0.736
LIG_FHA_1	201	207	PF00498	0.727
LIG_FHA_1	440	446	PF00498	0.602
LIG_FHA_1	460	466	PF00498	0.368
LIG_FHA_2	306	312	PF00498	0.758
LIG_Pex14_2	178	182	PF04695	0.561
LIG_Pex14_2	254	258	PF04695	0.688
LIG_SH2_CRK	116	120	PF00017	0.525
LIG_SH2_CRK	197	201	PF00017	0.658
LIG_SH2_CRK	67	71	PF00017	0.602
LIG_SH2_GRB2like	427	430	PF00017	0.603
LIG_SH2_NCK_1	153	157	PF00017	0.508
LIG_SH2_NCK_1	197	201	PF00017	0.512
LIG_SH2_NCK_1	67	71	PF00017	0.608
LIG_SH2_SRC	153	156	PF00017	0.508
LIG_SH2_STAP1	32	36	PF00017	0.650
LIG_SH2_STAP1	427	431	PF00017	0.645
LIG_SH2_STAP1	469	473	PF00017	0.661
LIG_SH2_STAT5	72	75	PF00017	0.674
LIG_SH3_3	236	242	PF00018	0.754
LIG_SH3_3	245	251	PF00018	0.691
LIG_SH3_3	295	301	PF00018	0.679
LIG_SH3_3	306	312	PF00018	0.550
LIG_SH3_3	35	41	PF00018	0.652
LIG_SH3_3	370	376	PF00018	0.643
LIG_SH3_3	473	479	PF00018	0.648
MOD_CK1_1	249	255	PF00069	0.714
MOD_CK1_1	278	284	PF00069	0.756
MOD_CK1_1	3	9	PF00069	0.699
MOD_CK1_1	363	369	PF00069	0.691
MOD_CK1_1	387	393	PF00069	0.753
MOD_CK2_1	224	230	PF00069	0.683
MOD_CK2_1	405	411	PF00069	0.730
MOD_GlcNHglycan	12	15	PF01048	0.711
MOD_GlcNHglycan	288	291	PF01048	0.783
MOD_GlcNHglycan	362	365	PF01048	0.721
MOD_GlcNHglycan	367	370	PF01048	0.731
MOD_GlcNHglycan	386	389	PF01048	0.719
MOD_GlcNHglycan	4	8	PF01048	0.701
MOD_GlcNHglycan	402	405	PF01048	0.662
MOD_GlcNHglycan	407	410	PF01048	0.679
MOD_GlcNHglycan	56	59	PF01048	0.651
MOD_GlcNHglycan	86	89	PF01048	0.684
MOD_GSK3_1	170	177	PF00069	0.485
MOD_GSK3_1	196	203	PF00069	0.686
MOD_GSK3_1	37	44	PF00069	0.601
MOD_GSK3_1	54	61	PF00069	0.504
MOD_LATS_1	398	404	PF00433	0.760
MOD_LATS_1	437	443	PF00433	0.605
MOD_NEK2_1	272	277	PF00069	0.808
MOD_NEK2_1	358	363	PF00069	0.692
MOD_PIKK_1	170	176	PF00454	0.485
MOD_PIKK_1	278	284	PF00454	0.729
MOD_PKA_2	134	140	PF00069	0.759
MOD_PKA_2	224	230	PF00069	0.701
MOD_PKA_2	327	333	PF00069	0.686
MOD_PKA_2	449	455	PF00069	0.611
MOD_PKB_1	168	176	PF00069	0.408
MOD_Plk_1	422	428	PF00069	0.635
MOD_Plk_2-3	224	230	PF00069	0.766
MOD_Plk_4	353	359	PF00069	0.485
MOD_Plk_4	387	393	PF00069	0.598
MOD_Plk_4	422	428	PF00069	0.669
MOD_ProDKin_1	144	150	PF00069	0.401
MOD_ProDKin_1	240	246	PF00069	0.595
MOD_ProDKin_1	294	300	PF00069	0.704
MOD_ProDKin_1	305	311	PF00069	0.739
MOD_ProDKin_1	37	43	PF00069	0.621
MOD_ProDKin_1	58	64	PF00069	0.657
MOD_SUMO_for_1	49	52	PF00179	0.683
TRG_DiLeu_BaLyEn_6	128	133	PF01217	0.673
TRG_DiLeu_BaLyEn_6	481	486	PF01217	0.621
TRG_ENDOCYTIC_2	116	119	PF00928	0.630
TRG_ENDOCYTIC_2	197	200	PF00928	0.605
TRG_ENDOCYTIC_2	379	382	PF00928	0.706
TRG_ER_diArg_1	126	129	PF00400	0.661
TRG_ER_diArg_1	138	141	PF00400	0.748
TRG_ER_diArg_1	166	168	PF00400	0.480
TRG_ER_diArg_1	217	219	PF00400	0.789
TRG_ER_diArg_1	351	353	PF00400	0.485
TRG_ER_diArg_1	486	488	PF00400	0.750
TRG_NLS_MonoExtN_4	167	172	PF00514	0.408

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBL9	Leptomonas seymouri	59%	87%
A0A1X0NJC7	Trypanosomatidae	34%	98%
A0A3R7RG79	Trypanosoma rangeli	35%	98%
A4HM79	Leishmania braziliensis	81%	100%
A4IAU2	Leishmania infantum	100%	100%
D0A2A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AEM0	Leishmania major	96%	100%
E9B5S9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%