LeishMANIAdb
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Hydrophilic acylated surface protein b

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hydrophilic acylated surface protein b
Gene product:
hydrophilic acylated surface protein b
Species:
Leishmania donovani
UniProt:
A0A3Q8IFV6_LEIDO
TriTrypDb:
LdCL_230019500 , LDHU3_23.1640
Length:
186

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IFV6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFV6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 15 17 PF00082 0.577
CLV_PCSK_PC1ET2_1 15 17 PF00082 0.577
DOC_USP7_UBL2_3 7 11 PF12436 0.626
LIG_SH2_STAT5 4 7 PF00017 0.537
MOD_GlcNHglycan 45 48 PF01048 0.745
MOD_GlcNHglycan 8 11 PF01048 0.692
MOD_N-GLC_1 43 48 PF02516 0.580
MOD_NEK2_1 43 48 PF00069 0.580
MOD_NMyristoyl 1 7 PF02799 0.621
MOD_PIKK_1 51 57 PF00454 0.581
MOD_PIKK_1 78 84 PF00454 0.568

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IB23 Leishmania donovani 60% 68%
A4I0F4 Leishmania infantum 62% 100%
E9AWB7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 94%
Q4QB56 Leishmania major 57% 94%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS