LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

p-nitrophenylphosphatase, putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
p-nitrophenylphosphatase, putative
Gene product:
p-nitrophenylphosphatase, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IFQ8_LEIDO
TriTrypDb:
LdBPK_312410.1 , LdCL_310032200 , LDHU3_31.4300
Length:
413

Annotations

Annotations by Jardim et al.

Phosphatase, p-nitrophenylphosphatase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3Q8IFQ8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFQ8

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 3
GO:0016787 hydrolase activity 2 3
GO:0016788 hydrolase activity, acting on ester bonds 3 2
GO:0016791 phosphatase activity 5 2
GO:0042578 phosphoric ester hydrolase activity 4 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 219 221 PF00082 0.624
CLV_PCSK_KEX2_1 323 325 PF00082 0.558
CLV_PCSK_PC1ET2_1 219 221 PF00082 0.526
CLV_PCSK_PC1ET2_1 323 325 PF00082 0.504
CLV_PCSK_SKI1_1 145 149 PF00082 0.425
CLV_PCSK_SKI1_1 395 399 PF00082 0.487
CLV_PCSK_SKI1_1 44 48 PF00082 0.599
CLV_PCSK_SKI1_1 68 72 PF00082 0.448
DEG_APCC_DBOX_1 43 51 PF00400 0.494
DEG_ODPH_VHL_1 180 191 PF01847 0.469
DOC_CYCLIN_RxL_1 142 152 PF00134 0.542
DOC_CYCLIN_yCln2_LP_2 25 31 PF00134 0.571
DOC_MAPK_DCC_7 17 27 PF00069 0.530
DOC_MAPK_gen_1 331 341 PF00069 0.415
DOC_PP1_RVXF_1 98 105 PF00149 0.538
DOC_PP2B_LxvP_1 214 217 PF13499 0.468
DOC_PP4_FxxP_1 20 23 PF00568 0.550
DOC_USP7_MATH_1 204 208 PF00917 0.602
DOC_USP7_MATH_1 266 270 PF00917 0.488
DOC_WW_Pin1_4 2 7 PF00397 0.551
DOC_WW_Pin1_4 282 287 PF00397 0.641
DOC_WW_Pin1_4 62 67 PF00397 0.575
LIG_14-3-3_CanoR_1 359 366 PF00244 0.387
LIG_14-3-3_CanoR_1 44 54 PF00244 0.604
LIG_Actin_WH2_2 249 266 PF00022 0.417
LIG_Actin_WH2_2 55 70 PF00022 0.477
LIG_BIR_III_4 203 207 PF00653 0.516
LIG_Clathr_ClatBox_1 71 75 PF01394 0.546
LIG_FHA_1 137 143 PF00498 0.561
LIG_FHA_1 184 190 PF00498 0.493
LIG_FHA_1 200 206 PF00498 0.587
LIG_FHA_1 283 289 PF00498 0.650
LIG_FHA_1 359 365 PF00498 0.425
LIG_FHA_1 53 59 PF00498 0.588
LIG_FHA_2 127 133 PF00498 0.621
LIG_FHA_2 290 296 PF00498 0.484
LIG_GBD_Chelix_1 403 411 PF00786 0.415
LIG_LIR_Apic_2 18 23 PF02991 0.523
LIG_LIR_Apic_2 207 212 PF02991 0.605
LIG_LIR_Gen_1 257 267 PF02991 0.447
LIG_LIR_Nem_3 257 263 PF02991 0.455
LIG_MYND_1 212 216 PF01753 0.558
LIG_NRBOX 143 149 PF00104 0.542
LIG_PTB_Apo_2 335 342 PF02174 0.388
LIG_SH2_CRK 267 271 PF00017 0.488
LIG_SH2_NCK_1 134 138 PF00017 0.627
LIG_SH2_PTP2 69 72 PF00017 0.384
LIG_SH2_STAP1 138 142 PF00017 0.573
LIG_SH2_STAP1 200 204 PF00017 0.565
LIG_SH2_STAT5 138 141 PF00017 0.594
LIG_SH2_STAT5 36 39 PF00017 0.559
LIG_SH2_STAT5 402 405 PF00017 0.507
LIG_SH2_STAT5 69 72 PF00017 0.365
LIG_SH2_STAT5 94 97 PF00017 0.543
LIG_SH3_3 176 182 PF00018 0.618
LIG_SH3_3 209 215 PF00018 0.618
LIG_SH3_3 26 32 PF00018 0.546
LIG_SH3_3 293 299 PF00018 0.523
LIG_SH3_3 60 66 PF00018 0.541
LIG_SUMO_SIM_par_1 374 379 PF11976 0.414
LIG_SUMO_SIM_par_1 70 75 PF11976 0.546
LIG_TRAF2_1 129 132 PF00917 0.615
LIG_TRAF2_1 154 157 PF00917 0.600
LIG_TRAF2_1 349 352 PF00917 0.545
LIG_TYR_ITIM 265 270 PF00017 0.488
LIG_TYR_ITIM 67 72 PF00017 0.414
LIG_UBA3_1 116 123 PF00899 0.600
MOD_CDC14_SPxK_1 65 68 PF00782 0.523
MOD_CDK_SPxK_1 62 68 PF00069 0.522
MOD_CK1_1 136 142 PF00069 0.642
MOD_CK1_1 15 21 PF00069 0.531
MOD_CK1_1 312 318 PF00069 0.519
MOD_CK2_1 126 132 PF00069 0.621
MOD_CK2_1 376 382 PF00069 0.404
MOD_Cter_Amidation 321 324 PF01082 0.566
MOD_GlcNHglycan 135 138 PF01048 0.349
MOD_GlcNHglycan 206 209 PF01048 0.554
MOD_GlcNHglycan 237 240 PF01048 0.680
MOD_GlcNHglycan 314 317 PF01048 0.455
MOD_GlcNHglycan 378 381 PF01048 0.427
MOD_GlcNHglycan 47 50 PF01048 0.556
MOD_GSK3_1 103 110 PF00069 0.546
MOD_GSK3_1 11 18 PF00069 0.551
MOD_GSK3_1 23 30 PF00069 0.525
MOD_GSK3_1 312 319 PF00069 0.474
MOD_N-GLC_1 107 112 PF02516 0.343
MOD_NEK2_1 116 121 PF00069 0.623
MOD_NEK2_1 376 381 PF00069 0.398
MOD_OFUCOSY 224 229 PF10250 0.498
MOD_PKA_2 358 364 PF00069 0.389
MOD_Plk_1 107 113 PF00069 0.543
MOD_Plk_2-3 126 132 PF00069 0.600
MOD_Plk_2-3 240 246 PF00069 0.553
MOD_Plk_4 302 308 PF00069 0.735
MOD_Plk_4 309 315 PF00069 0.524
MOD_Plk_4 371 377 PF00069 0.448
MOD_ProDKin_1 2 8 PF00069 0.552
MOD_ProDKin_1 282 288 PF00069 0.631
MOD_ProDKin_1 62 68 PF00069 0.577
TRG_ENDOCYTIC_2 267 270 PF00928 0.488
TRG_ENDOCYTIC_2 69 72 PF00928 0.397
TRG_ER_diArg_1 142 145 PF00400 0.601
TRG_Pf-PMV_PEXEL_1 277 281 PF00026 0.559

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P266 Leptomonas seymouri 41% 100%
A0A0S4IZ46 Bodo saltans 46% 100%
A0A422N412 Trypanosoma rangeli 56% 100%
A4HJL7 Leishmania braziliensis 87% 100%
A4I739 Leishmania infantum 100% 100%
A4I740 Leishmania infantum 42% 97%
A6NDG6 Homo sapiens 30% 100%
C9ZWP3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 52% 100%
D3ZDK7 Rattus norvegicus 31% 100%
E9B234 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
P0DKC3 Arabidopsis thaliana 31% 100%
P0DKC4 Arabidopsis thaliana 31% 100%
P19881 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 100%
P34492 Caenorhabditis elegans 27% 79%
Q00472 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
Q2T9S4 Bos taurus 29% 100%
Q3ZBF9 Bos taurus 31% 100%
Q4Q627 Leishmania major 93% 100%
Q5F4B1 Gallus gallus 29% 100%
Q8CHP8 Mus musculus 31% 100%
Q8GWU0 Arabidopsis thaliana 31% 100%
Q96GD0 Homo sapiens 31% 100%
V5D2X9 Trypanosoma cruzi 54% 95%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS